{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T06:25:41Z","timestamp":1793514341629,"version":"4.5.0"},"reference-count":57,"publisher":"Informa UK Limited","issue":"11","funder":[{"name":"Penelitian Fundamental Kolaboratif, Hasanuddin University, Makassar, Indonesia"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biomaterials Science, Polymer Edition"],"published-print":{"date-parts":[[2024,7,23]]},"DOI":"10.1080\/09205063.2024.2349414","type":"journal-article","created":{"date-parts":[[2024,5,21]],"date-time":"2024-05-21T03:45:21Z","timestamp":1716263121000},"page":"1726-1749","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":6,"title":["Specific delivery of metronidazole using microparticles and thermosensitive\n            <i>in situ<\/i>\n            hydrogel for intrapocket administration as an alternative in periodontitis treatment"],"prefix":"10.1080","volume":"35","author":[{"given":"Nurul Muhlisah","family":"Maddeppungeng","sequence":"first","affiliation":[{"name":"Department of Pharmacy, Faculty of Medicine and Health Sciences, Alauddin Islamic State University, Samata Gowa, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nor Atikah","family":"Syahirah","sequence":"additional","affiliation":[{"name":"Faculty of Pharmacy, Hasanuddin University, Makassar, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nasyrah","family":"Hidayati","sequence":"additional","affiliation":[{"name":"Department of Orthodontic, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fadhlil U. A.","family":"Rahman","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karima Qurnia","family":"Mansjur","sequence":"additional","affiliation":[{"name":"Department of Orthodontic, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irene E.","family":"Rieuwpassa","sequence":"additional","affiliation":[{"name":"Department of Oral Biology, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dian","family":"Setiawati","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Fadhlullah","sequence":"additional","affiliation":[{"name":"Veterinary Paramedic Study Program, Faculty of Vocational Study, Hasanuddin University, Makassar, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anugerah Yaumil Ramadhani","family":"Aziz","sequence":"additional","affiliation":[{"name":"Faculty of Pharmacy, Hasanuddin University, Makassar, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azimah","family":"Salsabila","sequence":"additional","affiliation":[{"name":"Faculty of Pharmacy, Hasanuddin University, Makassar, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad R.","family":"Alsayed","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy and Therapeutics, Applied Science Private University, Amman, Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boonnada","family":"Pamornpathomkul","sequence":"additional","affiliation":[{"name":"Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, Thailand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andi Dian","family":"Permana","sequence":"additional","affiliation":[{"name":"Faculty of Pharmacy, Hasanuddin University, Makassar, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafikah","family":"Hasyim","sequence":"additional","affiliation":[{"name":"Department of Oral Biology, Faculty of Dentistry, Hasanuddin University, Makassar, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2024,5,20]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro2873"},{"key":"e_1_3_3_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051x.1998.tb02419.x"},{"key":"e_1_3_3_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro2337"},{"key":"e_1_3_3_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/1721727X1301100217"},{"key":"e_1_3_3_6_1","doi-asserted-by":"crossref","unstructured":"Ababneh KT Faisal M Hwaij A et\u00a0al. Prevalence and risk indicators of gingivitis and periodontitis in a multi-centre study in North Jordan: a cross sectional study. BMC Oral Health. 2012;12:1. http:\/\/www.biomedcentral.com\/1472-6831\/12\/1.","DOI":"10.1186\/1472-6831-12-1"},{"key":"e_1_3_3_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.adaj.2018.04.023"},{"key":"e_1_3_3_8_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2000.0087"},{"key":"e_1_3_3_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.23-0063"},{"key":"e_1_3_3_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/idj.12146"},{"key":"e_1_3_3_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12441"},{"key":"e_1_3_3_12_1","doi-asserted-by":"crossref","unstructured":"Loesche WJ Grossman N Giordano J et\u00a0al. Metronidazole in periodontitis. J. Clin.Periodontol. 1993;20(2) 96\u2013104.","DOI":"10.1111\/j.1600-051X.1993.tb00336.x"},{"key":"e_1_3_3_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.1992.tb02533.x"},{"key":"e_1_3_3_14_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja211279u"},{"key":"e_1_3_3_15_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S84108"},{"key":"e_1_3_3_16_1","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines9080975"},{"key":"e_1_3_3_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2012.02.016"},{"key":"e_1_3_3_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/jps.20843"},{"key":"e_1_3_3_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2004.01.019"},{"key":"e_1_3_3_20_1","doi-asserted-by":"crossref","unstructured":"Jones DS Woolfson AD Brown AF et\u00a0al. Design characterisation and preliminary clinical evaluation of a novel mucoadhesive topical formulation containing tetracycline for the treatment of periodontal disease. 2000. www.elsevier.com\/locate\/jconrel.","DOI":"10.1016\/S0168-3659(00)00231-5"},{"key":"e_1_3_3_21_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24076364"},{"key":"e_1_3_3_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.ACTBIO.2022.03.046"},{"key":"e_1_3_3_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smaim.2023.02.001"},{"key":"e_1_3_3_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2023.114688"},{"key":"e_1_3_3_25_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.2c16857"},{"key":"e_1_3_3_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2018.07.102"},{"key":"e_1_3_3_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2020.111786"},{"key":"e_1_3_3_28_1","doi-asserted-by":"publisher","DOI":"10.34172\/ajdr.2019.01"},{"key":"e_1_3_3_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2021.118001"},{"key":"e_1_3_3_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jddst.2019.101134"},{"key":"e_1_3_3_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2016.04.021"},{"key":"e_1_3_3_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2005.01217.x"},{"key":"e_1_3_3_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2019.10.004"},{"key":"e_1_3_3_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmpb.2010.01.007"},{"key":"e_1_3_3_35_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-017-2297-6"},{"key":"e_1_3_3_36_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302X.2007.00336.x"},{"key":"e_1_3_3_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/0471141755.ph13a08s50"},{"key":"e_1_3_3_38_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.7.2612-2617.2005"},{"key":"e_1_3_3_39_1","doi-asserted-by":"publisher","DOI":"10.1186\/s11671-017-2249-8"},{"key":"e_1_3_3_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2006.11.061"},{"key":"e_1_3_3_41_1","doi-asserted-by":"publisher","DOI":"10.3109\/10717544.2012.657718"},{"key":"e_1_3_3_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-814130-4.00011-7"},{"key":"e_1_3_3_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-77668-2_5"},{"key":"e_1_3_3_44_1","doi-asserted-by":"publisher","DOI":"10.3390\/polym11050820"},{"key":"e_1_3_3_45_1","doi-asserted-by":"publisher","DOI":"10.31838\/ijprt\/08.01.02"},{"key":"e_1_3_3_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2013.11.010"},{"key":"e_1_3_3_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2019.05.036"},{"key":"e_1_3_3_48_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmat4474"},{"key":"e_1_3_3_49_1","doi-asserted-by":"publisher","DOI":"10.1039\/d3tb02610h"},{"key":"e_1_3_3_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2014.08.035"},{"key":"e_1_3_3_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2019.12.040"},{"key":"e_1_3_3_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.CARBPOL.2021.118999"},{"key":"e_1_3_3_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2019.02.001"},{"key":"e_1_3_3_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpb.2008.09.028"},{"key":"e_1_3_3_55_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics9040053"},{"issue":"2","key":"e_1_3_3_56_1","first-page":"65","article-title":"Microencapsulation: a promising technique for controlled drug delivery","volume":"5","author":"Singh MN","year":"2010","unstructured":"Singh MN, Hemant KSY, Ram M, et\u00a0al. Microencapsulation: a promising technique for controlled drug delivery. Res Pharm Sci. 2010;5(2):65\u201377.","journal-title":"Res Pharm Sci"},{"key":"e_1_3_3_57_1","doi-asserted-by":"publisher","DOI":"10.5958\/0974-360X.2017.00323.7"},{"key":"e_1_3_3_58_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro.2016.94"}],"container-title":["Journal of Biomaterials Science, Polymer Edition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/09205063.2024.2349414","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,24]],"date-time":"2024-09-24T19:34:21Z","timestamp":1727206461000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/09205063.2024.2349414"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,20]]},"references-count":57,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2024,7,23]]}},"alternative-id":["10.1080\/09205063.2024.2349414"],"URL":"https:\/\/doi.org\/10.1080\/09205063.2024.2349414","relation":{},"ISSN":["0920-5063","1568-5624"],"issn-type":[{"value":"0920-5063","type":"print"},{"value":"1568-5624","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,20]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=tbsp20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=tbsp20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2024-01-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-04-25","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}