{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T06:32:18Z","timestamp":1792650738199,"version":"4.5.0"},"reference-count":41,"publisher":"Portico","issue":"1-2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["European Journal of Morphology"],"published-print":{"date-parts":[[2005,4,1]]},"DOI":"10.1080\/09243860500095117","type":"journal-article","created":{"date-parts":[[2005,9,7]],"date-time":"2005-09-07T17:29:56Z","timestamp":1126114196000},"page":"3-11","source":"Crossref","is-referenced-by-count":12,"title":["Microdamage in porcine alveolar bone due to functional and orthodontic loading"],"prefix":"10.3730","volume":"42","author":[{"given":"Carlalberta","family":"Verna","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Dalstra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T Clive","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Birte","family":"Melsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1320","reference":[{"key":"E00001","doi-asserted-by":"crossref","unstructured":"Bien, SM. Hydrodynamic damping of tooth movement J Dent Res, 1966; 45: 907\u200a\u2013\u200a914","DOI":"10.1177\/00220345660450036701"},{"key":"E00002","doi-asserted-by":"crossref","unstructured":"Bouvier, M, Hylander, WL. The mechanical or metabolic function of secondary osteonal bone in the monkey Macaca fascicularis Arch Oral Biol, 1996; 41: 941\u200a\u2013\u200a950","DOI":"10.1016\/S0003-9969(96)00047-7"},{"key":"E00003","doi-asserted-by":"crossref","unstructured":"Boyce, TM, Fyhrie, DP, Glotkowski, MC, Radin, EL, Schaffler, MB. Damage type and strain mode associations in human compact bone bending fatigue J Orthop Res, 1998; 16: 322\u200a\u2013\u200a329","DOI":"10.1002\/jor.1100160308"},{"key":"E00004","doi-asserted-by":"crossref","unstructured":"Burr, DB. Remodeling and the repair of fatigue damage Calcif Tissue Int, 1993; 53(Suppl. 1): S75\u200a\u2013\u200a80","DOI":"10.1007\/BF01673407"},{"key":"E00005","doi-asserted-by":"crossref","unstructured":"Burr, DB. Targeted and nontargeted remodeling Bone, 2002; 30: 2\u200a\u2013\u200a4","DOI":"10.1016\/S8756-3282(01)00619-6"},{"key":"E00006","doi-asserted-by":"crossref","unstructured":"Burr, DB, Martin, RB, Schaffler, MB, Radin, EL. Bone remodeling in response to in vivo fatigue microdamage J Biomech, 1985; 18: 189\u200a\u2013\u200a200","DOI":"10.1016\/0021-9290(85)90204-0"},{"key":"E00007","unstructured":"Dalstra, M, Cattaneo, PM, Beckmann, F, Hauge, EM. Microtomography of cortical bone using a synchrotron source 2003; p 283\u200a\u2013\u200a287 H.M.Hamza. Rhodes, ACTA PressProceedings on the IASTED International Conference on Biomechanics"},{"key":"E00008","doi-asserted-by":"crossref","unstructured":"Davidovitch, Z, Finkelson, MD, Steigman, S, Shanfeld, JL, Montgomery, PC, Korostoff, E. Electric currents, bone remodeling, and orthodontic tooth movement. I. The effect of electric currents on periodontal cyclic nucleotides Am J Orthodont, 1980; 77: 14\u200a\u2013\u200a32","DOI":"10.1016\/0002-9416(80)90221-3"},{"key":"E00009","doi-asserted-by":"crossref","unstructured":"Davidovitch, Z, Nicolay, OF, Ngan, PW, Shanfeld, JL. Neurotransmitters, cytokines, and the control of alveolar bone remodeling in orthodontics Dent Clin North Am, 1988; 32: 411\u200a\u2013\u200a435","DOI":"10.1016\/S0011-8532(22)00320-2"},{"key":"E00010","doi-asserted-by":"crossref","unstructured":"Epker, BN, Frost, HM. Correlation of bone resorption and formation with the physical behavior of loaded bone J Dent Res, 1965; 44: 33\u200a\u2013\u200a41","DOI":"10.1177\/00220345650440012801"},{"key":"E00011","doi-asserted-by":"crossref","unstructured":"Frost, HM. Presence of microscopic cracks in vivo in bone Henry Ford Hospital Med Bull, 1960; 8: 25\u200a\u2013\u200a35","DOI":"10.3109\/10520296009114729"},{"key":"E00012","doi-asserted-by":"crossref","unstructured":"Gerstner, GE. Intermittency in mastication and apomorphine-induced gnawing Physiol Behav, 1998; 65: 569\u200a\u2013\u200a574","DOI":"10.1016\/S0031-9384(98)00200-5"},{"key":"E00013","doi-asserted-by":"crossref","unstructured":"Gerstner, GE, Cianfarani, T. Temporal dynamics of human masticatory sequences Physiol Behav, 1998; 64: 457\u200a\u2013\u200a461","DOI":"10.1016\/S0031-9384(98)00107-3"},{"key":"E00014","doi-asserted-by":"crossref","unstructured":"Hamaya, M, Mizoguchi, I, Sakakura, Y, Yajima, T, Abiko, Y. Cell death of osteocytes occurs in rat alveolar bone during experimental tooth movement Calcif Tissue Int, 2002; 70: 117\u200a\u2013\u200a126","DOI":"10.1007\/s002230010021"},{"key":"E00015","doi-asserted-by":"crossref","unstructured":"Heller, IJ, Nanda, R. Effect of metabolic alteration of periodontal fibers on orthodontic tooth movement. An experimental study Am J Orthodont, 1979; 75: 239\u200a\u2013\u200a258","DOI":"10.1016\/0002-9416(79)90272-0"},{"key":"E00016","doi-asserted-by":"crossref","unstructured":"Herring, SW. The dynamics of mastication in pigs Arch Oral Biol, 1976; 21: 473\u200a\u2013\u200a480","DOI":"10.1016\/0003-9969(76)90105-9"},{"key":"E00017","doi-asserted-by":"crossref","unstructured":"Herring, SW, Rafferty, KL, Liu, ZJ, Marshall, CD. Jaw muscles and the skull in mammals: the biomechanics of mastication Comp Biochem Physiol A Mol Integr Physiol, 2001; 131: 207\u200a\u2013\u200a219","DOI":"10.1016\/S1095-6433(01)00472-X"},{"key":"E00018","doi-asserted-by":"crossref","unstructured":"Huja, SS, Katona, TR, Burr, DB, Garetto, LP, Roberts, WE. Microdamage adjacent to endosseous implants Bone, 1999; 25: 217\u200a\u2013\u200a222","DOI":"10.1016\/S8756-3282(99)00151-9"},{"key":"E00019","unstructured":"Kehoe, MJ, Cohen, SM, Zarrinnia, K, Cowan, A. The effect of acetaminophen, ibuprofen, and misoprostol on prostaglandin E2 synthesis and the degree and rate of orthodontic tooth movement Angle Orthodont, 1996; 66: 339\u200a\u2013\u200a349"},{"key":"E00020","doi-asserted-by":"crossref","unstructured":"Korioth, TW, Romilly, DP, Hannam, AG. Three-dimensional finite element stress analysis of the dentate human mandible Am J Phys Anthropol, 1992; 88: 69\u200a\u2013\u200a96","DOI":"10.1002\/ajpa.1330880107"},{"key":"E00021","doi-asserted-by":"crossref","unstructured":"Lee, TC, Myers, ER, Hayes, WC. Fluorescence-aided detection of microdamage in compact bone J Anat, 1998; 193(Pt 2): 179\u200a\u2013\u200a184","DOI":"10.1046\/j.1469-7580.1998.19320179.x"},{"key":"E00022","doi-asserted-by":"crossref","unstructured":"Lee, TC, O'Brien, FJ, Taylor, D. The nature of fatigue damage in bone Int J Fatigue, 2000; 22: 847\u200a\u2013\u200a853","DOI":"10.1016\/S0142-1123(00)00054-2"},{"key":"E00023","doi-asserted-by":"crossref","unstructured":"Lee, TC, Staines, A, Taylor, D. Bone adaptation to load: microdamage as a stimulus for bone remodelling J Anat, 2002; 201: 437\u200a\u2013\u200a446","DOI":"10.1046\/j.1469-7580.2002.00123.x"},{"key":"E00024","unstructured":"Marotti, G. The structure of bone tissues and the cellular control of their deposition Ital J Anat Embryol, 1996; 101: 25\u200a\u2013\u200a79"},{"key":"E00025","doi-asserted-by":"crossref","unstructured":"Martin, RB. Fatigue microdamage as an essential element of bone mechanics and biology Calcif Tissue Int, 2003; 73: 101\u200a\u2013\u200a107","DOI":"10.1007\/s00223-002-1059-9"},{"key":"E00026","doi-asserted-by":"crossref","unstructured":"Melsen, B. Tissue reaction to orthodontic tooth movement \u2013 a new paradigm Eur J Orthodont, 2001; 23: 671\u200a\u2013\u200a681","DOI":"10.1093\/ejo\/23.6.671"},{"key":"E00027","doi-asserted-by":"crossref","unstructured":"Miyamoto, K, Ishizuka, Y, Ueda, HM, Saifuddin, M, Shikata, N, Tanne, K. Masseter muscle activity during the whole day in children and young adults J Oral Rehab, 1999; 26: 858\u200a\u2013\u200a864","DOI":"10.1046\/j.1365-2842.1999.00478.x"},{"key":"E00028","doi-asserted-by":"crossref","unstructured":"Noble, B. Bone microdamage and cell apoptosis Eur Cell Mater, 2003; 6: 46\u200a\u2013\u200a55","DOI":"10.22203\/eCM.v006a05"},{"key":"E00029","doi-asserted-by":"crossref","unstructured":"Parfitt, AM. Targeted and nontargeted bone remodeling: relationship to basic multicellular unit origination and progression Bone, 2002; 30: 5\u200a\u2013\u200a7","DOI":"10.1016\/S8756-3282(01)00642-1"},{"key":"E00030","doi-asserted-by":"crossref","unstructured":"Reilly, GC, Currey, JD. The development of microcracking and failure in bone depends on the loading mode to which it is adapted J Exp Biol, 1999; 202(Pt 5): 543\u200a\u2013\u200a552","DOI":"10.1242\/jeb.202.5.543"},{"key":"E00031","doi-asserted-by":"crossref","unstructured":"Reitan, K. Clinical and histologic observations on tooth movement during and after orthodontic treatment Am J Orthodont, 1967; 53: 721\u200a\u2013\u200a745","DOI":"10.1016\/0002-9416(67)90118-2"},{"key":"E00032","unstructured":"Reitan, K, Rygh, P. Biomechanical principles and reactions 1994; p 96\u200a\u2013\u200a192 In: Graber TM, Vanarsdall RL, editors. Orthodontics: current orthodontic concept and techniquesSt. Louis, MO: CV Mosby"},{"key":"E00033","doi-asserted-by":"crossref","unstructured":"Saffar, JL, Lasfargues, JJ, Cherruau, M. Alveolar bone and the alveolar process: the socket that is never stable Periodontology, 1997; 13: 76\u200a\u2013\u200a90","DOI":"10.1111\/j.1600-0757.1997.tb00096.x"},{"key":"E00034","doi-asserted-by":"crossref","unstructured":"Sandy, JR, Farndale, RW, Meikle, MC. Recent advances in understanding mechanically induced bone remodeling and their relevance to orthodontic theory and practice Am J Orthodont Dentofacial Orthop, 1993; 103: 212\u200a\u2013\u200a222","DOI":"10.1016\/0889-5406(93)70002-6"},{"key":"E00035","unstructured":"Tricker, ND, Dixon, RB, Garetto, LP. Cortical bone turnover and mineral apposition in dentate dog mandible 1998; 1[1]. 28th International workshop on hard tissue biology"},{"key":"E00036","doi-asserted-by":"crossref","unstructured":"Tuncay, OC, Ho, D, Barker, MK. Oxygen tension regulates osteoblast function Am J Orthodont Dentofacial Orthop, 1994; 105: 457\u200a\u2013\u200a463","DOI":"10.1016\/S0889-5406(94)70006-0"},{"key":"E00037","doi-asserted-by":"crossref","unstructured":"Verborgt, O, Gibson, GJ, Schaffler, MB. Loss of osteocyte integrity in association with microdamage and bone remodeling after fatigue in vivo [In Process Citation] J Bone Miner Res, 2000; 15: 60\u200a\u2013\u200a67","DOI":"10.1359\/jbmr.2000.15.1.60"},{"key":"E00038","doi-asserted-by":"crossref","unstructured":"Verna, C, Melsen, B, Melsen, F. Differences in static cortical bone remodeling parameters in human mandible and iliac crest Bone, 1999; 25: 577\u200a\u2013\u200a583","DOI":"10.1016\/S8756-3282(99)00206-9"},{"key":"E00039","doi-asserted-by":"crossref","unstructured":"Weinbaum, S, Cowin, SC, Zeng, Y. A model for the excitation of osteocytes by mechanical loading-induced bone fluid shear stresses J Biomech, 1994; 27: 339\u200a\u2013\u200a360","DOI":"10.1016\/0021-9290(94)90010-8"},{"key":"E00040","doi-asserted-by":"crossref","unstructured":"Yamasaki, K, Shibata, Y, Imai, S, Tani, Y, Shibasaki, Y, Fukuhara, T. Clinical application of prostaglandin E1 (PGE1) upon orthodontic tooth movement Am J Orthod, 1984; 85: 508\u200a\u2013\u200a518","DOI":"10.1016\/0002-9416(84)90091-5"},{"key":"E00041","doi-asserted-by":"crossref","unstructured":"Zengo, AN, Pawluk, RJ, Bassett, CA. Stress-induced bioelectric potentials in the dentoalveolar complex Am J Orthodont, 1973; 64: 17\u200a\u2013\u200a27","DOI":"10.1016\/0002-9416(73)90277-7"}],"container-title":["European Journal of Morphology"],"original-title":[],"deposited":{"date-parts":[[2023,5,4]],"date-time":"2023-05-04T11:16:38Z","timestamp":1683198998000},"score":1,"resource":{"primary":{"URL":"http:\/\/access.portico.org\/stable?au=pggtrn2dgd"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,4,1]]},"references-count":41,"aliases":["10.1080\/ejom.42.1-2.0003"],"journal-issue":{"issue":"1-2","published-print":{"date-parts":[[2005,4,1]]}},"alternative-id":["K3126551T74J180H"],"URL":"https:\/\/doi.org\/10.1080\/09243860500095117","relation":{},"ISSN":["0924-3860"],"issn-type":[{"value":"0924-3860","type":"print"}],"subject":[],"published":{"date-parts":[[2005,4,1]]}}}