{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T17:41:54Z","timestamp":1783705314649,"version":"3.55.0"},"reference-count":56,"publisher":"Informa UK Limited","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Platelets"],"published-print":{"date-parts":[[2005,11]]},"DOI":"10.1080\/09537100500163424","type":"journal-article","created":{"date-parts":[[2005,10,19]],"date-time":"2005-10-19T18:32:47Z","timestamp":1129746767000},"page":"415-429","source":"Crossref","is-referenced-by-count":15,"title":["Evidence that the purinergic receptor P2Y<sub>12<\/sub>potentiates platelet shape change by a Rho kinase-dependent mechanism"],"prefix":"10.1080","volume":"16","author":[{"given":"Adam R.","family":"Hardy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Darryl J.","family":"Hill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alastair W.","family":"Poole","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2009,7,7]]},"reference":[{"key":"CIT0001","volume-title":"Cerebrovascular Diseases","author":"Easton JD."},{"issue":"4","key":"CIT0003","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1055\/s-0037-1615655","volume":"85","author":"Eckly A","year":"2001","journal-title":"Thromb Haemost"},{"issue":"3","key":"CIT0004","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/S0031-6997(24)01373-5","volume":"50","author":"Ralevic V","year":"1998","journal-title":"Pharmacol Rev"},{"issue":"12","key":"CIT0005","doi-asserted-by":"crossref","first-page":"1731","DOI":"10.1172\/JCI8399","volume":"104","author":"Leon C","year":"1999","journal-title":"J Clin Invest"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1038\/35051599"},{"issue":"10","key":"CIT0007","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1038\/13522","volume":"5","author":"Fabre JE","year":"1999","journal-title":"Nature Medicine"},{"issue":"5","key":"CIT0009","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1080\/09537100050129305","volume":"11","author":"Wilde JI","year":"2000","journal-title":"Platelets"},{"issue":"23","key":"CIT0011","doi-asserted-by":"crossref","first-page":"5878","DOI":"10.1046\/j.1432-1033.2002.03305.x","volume":"269","author":"Riondino S","year":"2002","journal-title":"Eur J Biochem"},{"issue":"5","key":"CIT0012","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1182\/blood.V94.5.1665","volume":"94","author":"Bauer M","year":"1999","journal-title":"Blood"},{"issue":"3","key":"CIT0013","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1080\/0953710031000092794","volume":"14","author":"Paul BZ","year":"2003","journal-title":"Platelets"},{"issue":"42","key":"CIT0014","doi-asserted-by":"crossref","first-page":"39493","DOI":"10.1074\/jbc.M207256200","volume":"277","author":"Nieswandt B","year":"2002","journal-title":"J Biol Chem"},{"issue":"12","key":"CIT0015","doi-asserted-by":"crossref","first-page":"3513","DOI":"10.1046\/j.1432-1327.2001.02252.x","volume":"268","author":"Jung SM","year":"2001","journal-title":"Eur J Biochem"},{"issue":"48","key":"CIT0016","first-page":"46035","author":"Yang J","journal-title":"Redundancy and specificity in the regulation of adenylyl cyclase and other effectors. J Biol Chem"},{"issue":"2","key":"CIT0017","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1097\/00001721-199603000-00035","volume":"7","author":"Savi P","year":"1996","journal-title":"Blood Coagul Fibrinolysis"},{"issue":"11","key":"CIT0018","doi-asserted-by":"crossref","first-page":"2019","DOI":"10.1096\/fj.00-0810fje","author":"Hirsch E","journal-title":"FASEB J"},{"issue":"2","key":"CIT0019","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0014-5793(01)02824-1","volume":"505","author":"Kauffenstein G","year":"2001","journal-title":"FEBS Lett"},{"issue":"19","key":"CIT0020","doi-asserted-by":"crossref","first-page":"11358","DOI":"10.1074\/jbc.270.19.11358","volume":"270","author":"Kovacsovics TJ","year":"1995","journal-title":"J Biol Chem"},{"issue":"12","key":"CIT0021","doi-asserted-by":"crossref","first-page":"4156","DOI":"10.1182\/blood.V94.12.4156","volume":"94","author":"Trumel C","year":"1999","journal-title":"Blood"},{"issue":"14","key":"CIT0022","doi-asserted-by":"crossref","first-page":"12009","DOI":"10.1074\/jbc.M111803200","volume":"277","author":"Lova P","year":"2002","journal-title":"J Biol Chem"},{"issue":"26","key":"CIT0023","doi-asserted-by":"crossref","first-page":"23382","DOI":"10.1074\/jbc.M202212200","volume":"277","author":"Woulfe D","year":"2002","journal-title":"J Biol Chem"},{"issue":"4","key":"CIT0024","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1182\/blood-2002-05-1533","author":"Larson MK","journal-title":"Blood"},{"issue":"1","key":"CIT0025","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1111\/j.1538-7836.2004.00556.x","volume":"2","author":"Soulet C","year":"2004","journal-title":"J Thromb Haemost"},{"issue":"1","key":"CIT0027","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1080\/0953710021000062914","volume":"14","author":"Jagroop IA","year":"2003","journal-title":"Platelets"},{"issue":"2","key":"CIT0028","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1080\/09537105310001645960","volume":"15","author":"Jagroop IA","year":"2004","journal-title":"Platelets"},{"issue":"4","key":"CIT0029","first-page":"2024","volume":"273","author":"Daniel JL","year":"1998","journal-title":"I. Evidence for three distinct ADP receptors on human platelets. J Biol Chem"},{"issue":"1","key":"CIT0031","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1111\/j.1476-5381.1995.tb16326.x","volume":"115","author":"Poole AW","year":"1995","journal-title":"Brit J Pharmacol"},{"issue":"4","key":"CIT0032","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1046\/j.1365-2141.2003.04166.x","volume":"120","author":"Contreres JO","year":"2003","journal-title":"Brit J Haematol"},{"issue":"6","key":"CIT0033","doi-asserted-by":"crossref","first-page":"2113","DOI":"10.1182\/blood.V100.6.2113","volume":"100","author":"Falet H","year":"2002","journal-title":"Blood"},{"key":"CIT0034","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1182\/blood.V70.1.307.307","volume":"70","author":"Shattil SJ","year":"1987","journal-title":"Blood"},{"key":"CIT0035","doi-asserted-by":"crossref","first-page":"4219","DOI":"10.1128\/MCB.23.12.4219-4229.2003","volume":"23","author":"Riento K","year":"2003","journal-title":"Mol Cell Biol"},{"issue":"3","key":"CIT0037","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/S0014-2999(01)00733-6","volume":"412","author":"Baurand A","year":"2001","journal-title":"Eur J Pharmacol"},{"issue":"4","key":"CIT0038","first-page":"346","volume":"86","author":"Cattaneo M","year":"2001","journal-title":"Haematologica"},{"issue":"1","key":"CIT0039","first-page":"222","volume":"86","author":"Gachet C.","year":"2001","journal-title":"Thromb Haemost"},{"issue":"2","key":"CIT0040","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S1471-4892(03)00007-9","author":"Kunapuli SP","journal-title":"Curr Opin Pharmacol"},{"issue":"3","key":"CIT0041","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1124\/mol.63.3.639","volume":"63","author":"Resendiz JC","year":"2003","journal-title":"Molec Pharmacol"},{"issue":"6","key":"CIT0042","doi-asserted-by":"crossref","first-page":"1745","DOI":"10.1182\/blood-2004-02-0534","author":"Hardy AR","journal-title":"Blood"},{"key":"CIT0043","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/S0165-6147(00)01596-0","volume":"22","author":"Fukata Y","year":"2001","journal-title":"Trends Pharmacol Sci"},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.1126\/science.273.5272.245"},{"issue":"1","key":"CIT0045","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S0143-4160(03)00170-2","volume":"35","author":"Fox SC","year":"2004","journal-title":"Cell Calcium"},{"issue":"2","key":"CIT0046","first-page":"119","author":"Sage SO","journal-title":"Cell Calcium"},{"key":"CIT0047","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1055\/s-0037-1615614","volume":"85","author":"Missy K","year":"2001","journal-title":"Thromb Haemost"},{"issue":"2","key":"CIT0048","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1080\/09537100020032846","volume":"12","author":"Maayani S","year":"2001","journal-title":"Platelets"},{"issue":"12","key":"CIT0049","doi-asserted-by":"crossref","first-page":"1591","DOI":"10.1172\/JCI12242","volume":"107","author":"Foster CJ","year":"2001","journal-title":"J Clin Invest"},{"key":"CIT0050","doi-asserted-by":"crossref","first-page":"2256","DOI":"10.2337\/diabetes.51.7.2256","volume":"51","author":"Begum N","year":"2002","journal-title":"Diabetes"},{"issue":"4","key":"CIT0051","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1083\/jcb.144.4.745","volume":"144","author":"Klages B","year":"1999","journal-title":"J Cell Biol"},{"key":"CIT0052","doi-asserted-by":"crossref","first-page":"6543","DOI":"10.4049\/jimmunol.164.12.6543","volume":"164","author":"Essler M","year":"2000","journal-title":"J Immunol"},{"key":"CIT0053","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1006\/bbrc.2000.4194","volume":"280","author":"Sawada N","year":"2001","journal-title":"Biochem Biophys Res Commun"},{"key":"CIT0054","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1016\/S0024-3205(01)01189-4","volume":"69","author":"Ishii-Watabe A","year":"2001","journal-title":"Life Sci"},{"issue":"34","key":"CIT0055","doi-asserted-by":"crossref","first-page":"20246","DOI":"10.1074\/jbc.271.34.20246","volume":"271","author":"Amano M","year":"1996","journal-title":"J Biol Chem"},{"key":"CIT0056","doi-asserted-by":"publisher","DOI":"10.1021\/jm981072s"},{"issue":"12","key":"CIT0057","first-page":"9958","volume":"277","author":"Crosby D","year":"2002","journal-title":"Cross-talk between tyrosine and serine\/threonine kinases. J Biol Chem"},{"issue":"9","key":"CIT0058","doi-asserted-by":"crossref","first-page":"3552","DOI":"10.1182\/blood-2004-07-2893","volume":"105","author":"Hardy AR","year":"2005","journal-title":"Blood"},{"issue":"1","key":"CIT0059","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1080\/09537100075760","volume":"11","author":"Jagroop IA","year":"2000","journal-title":"Platelets"},{"key":"CIT0060","volume-title":"Biochem J","author":"Amano T"},{"issue":"4","key":"CIT0061","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1091\/mbc.12.4.1131","volume":"12","author":"Toshima J","year":"2001","journal-title":"Mol Biol Cell"},{"issue":"10","key":"CIT0062","doi-asserted-by":"crossref","first-page":"5749","DOI":"10.4049\/jimmunol.167.10.5749","volume":"167","author":"Lou Z","year":"2001","journal-title":"J Immunol"}],"container-title":["Platelets"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/09537100500163424","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,5]],"date-time":"2025-01-05T02:26:17Z","timestamp":1736043977000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.1080\/09537100500163424"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,11]]},"references-count":56,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2009,7,7]]},"published-print":{"date-parts":[[2005,11]]}},"alternative-id":["10.1080\/09537100500163424"],"URL":"https:\/\/doi.org\/10.1080\/09537100500163424","relation":{},"ISSN":["0953-7104","1369-1635"],"issn-type":[{"value":"0953-7104","type":"print"},{"value":"1369-1635","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,11]]}}}