{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T19:19:05Z","timestamp":1771874345413,"version":"3.50.1"},"reference-count":51,"publisher":"Informa UK Limited","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Radiation Biology"],"published-print":{"date-parts":[[1988,1]]},"DOI":"10.1080\/09553008814551241","type":"journal-article","created":{"date-parts":[[2007,7,7]],"date-time":"2007-07-07T04:09:57Z","timestamp":1183781397000},"page":"875-890","source":"Crossref","is-referenced-by-count":62,"title":["Modulation of Radiation-induced Chromosome Aberrations by DMSO, an OH Radical Scavenger. 1: Dose\u2014response Studies in Human Lymphocytes Exposed to 220 kV X-rays"],"prefix":"10.1080","volume":"53","author":[{"given":"L.G.","family":"Littlefield","sequence":"first","affiliation":[{"name":"Radiation Emergency Assistance Center\/Training Site (REAC\/TS), Oak Ridge Associated Universities, PO. Box 117, Oak Ridge, TN, 37831, U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.E.","family":"Joiner","sequence":"additional","affiliation":[{"name":"Mathematic Sciences, Oak Ridge National Laboratory, Oak Ridge, TN, 37831, U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.P.","family":"Colyer","sequence":"additional","affiliation":[{"name":"Radiation Emergency Assistance Center\/Training Site (REAC\/TS), Oak Ridge Associated Universities, PO. Box 117, Oak Ridge, TN, 37831, U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.M.","family":"Sayer","sequence":"additional","affiliation":[{"name":"Mathematic Sciences, Oak Ridge National Laboratory, Oak Ridge, TN, 37831, U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.L.","family":"Frome","sequence":"additional","affiliation":[{"name":"Radiation Emergency Assistance Center\/Training Site (REAC\/TS), Oak Ridge Associated Universities, PO. Box 117, Oak Ridge, TN, 37831, U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2009,7,3]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"21","article-title":"Lack of genetic damage in mammalian cells after cryopreservation at -196\u00b0C","volume":"7","author":"Ashwood-Smith M.J","year":"1979","unstructured":"Ashwood-Smith M.J. Lack of genetic damage in mammalian cells after cryopreservation at -196\u00b0C. Experimental Hematology 1979; 7: 21\u201326","journal-title":"Experimental Hematology"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1975.tb25363.x"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1967.tb34865.x"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/09553006114550051"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-4076(81)90072-5"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01214638"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01214637"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0027-5107(73)90007-9"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-81519-5"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-035409-2.50010-2"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01326894"},{"key":"e_1_2_1_13_1","volume-title":"Fifth Symposium on Microdosimetry","author":"Chapman J.D.","year":"1976","unstructured":"Chapman J.D., Reuvers A.P., Doern S.D., Gillespie C.J., Dugle D.L. Radiation chemical probes in the study of mammalian cell inactivation and their influence on radiobiological effectiveness. Fifth Symposium on Microdosimetry, J. Booz, H.G. Epert, B.G.R. Smith. Commission of the European Communities. 1976"},{"key":"e_1_2_1_14_1","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1016\/B978-0-12-523350-7.50073-0","volume-title":"Radiation Research","author":"Chapman J.D.","year":"1975","unstructured":"Chapman J.D., Dugle D.L., Reuvers A.P., Gillespie C.J., Borsa J. Chemical radiosensitization studies with mammalian cells growing in vitro. Radiation Research. Academic Press, Inc. 1975 a; 752\u2013760"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.2307\/3574272"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.2307\/3573667"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.2307\/3576871"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/276629a0"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.2307\/3573230"},{"key":"e_1_2_1_20_1","first-page":"611","volume-title":"Advances in Physical and Biological Radiation Detectors. Proceedings of a Symposium","author":"Dolphin G.W.","year":"1970","unstructured":"Dolphin G.W., Purrott R.J. Use of radiation-induced chromosome aberrations in human lymphocytes for dosimetry. Advances in Physical and Biological Radiation Detectors. Proceedings of a Symposium. International Atomic Energy Agency, Vienna, Austria 1970; 611\u2013622"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.2307\/2531244"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.2307\/3574271"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01190145"},{"key":"e_1_2_1_24_1","first-page":"665","article-title":"Temperature and the formation of radiation-induced chromosome aberrations. I. The effect of irradiation temperature","volume":"49","author":"Gumrich K.","year":"1986","unstructured":"Gumrich K., Virsik-Peuckert R.P., Harder D. Temperature and the formation of radiation-induced chromosome aberrations. I. The effect of irradiation temperature. International Journal of Radiation Biology 1986; 49: 665\u2013672","journal-title":"International Journal of Radiation Biology"},{"key":"e_1_2_1_25_1","volume-title":"Quantitative concepts and dosimetry in radiobiology","author":"ICRU","year":"1979","unstructured":"ICRU. Quantitative concepts and dosimetry in radiobiology. Report No. 30, International Commission on Radiation Units and Measurements, Washington, D.C. 1979"},{"key":"e_1_2_1_26_1","doi-asserted-by":"publisher","DOI":"10.2307\/3571727"},{"key":"e_1_2_1_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0033-7560(69)80077-3"},{"key":"e_1_2_1_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02982830"},{"issue":"8","key":"e_1_2_1_29_1","first-page":"61","article-title":"Modulation of radiation-induced chromosome aberrations by DMSO\u2014an OH radical scavenger","volume":"9","author":"Littlefield L.G.","year":"1987","unstructured":"Littlefield L.G., Joiner E.E., Frome E.L., Colyer S.P. Modulation of radiation-induced chromosome aberrations by DMSO\u2014an OH radical scavenger. Environmental Mutagenesis 1987 a; 9(8)61\u201361","journal-title":"Environmental Mutagenesis"},{"key":"e_1_2_1_30_1","unstructured":"Littlefield L.G. Joiner E.E. Frome E.L. Colyer S.P. Sayer A.M. Modification of X-ray induced chromosome aberrations-radioprotection by DMSO. Radiation Research: Proceedings of the 8th International Congress of Radiation Research EdinburghScotland July 1987 E.M. Fielden J.F. Fowler J.H. Hendry D. Scott. Taylor & Francis Ltd. London 1987 b; 1: 146\u2013146"},{"key":"e_1_2_1_31_1","first-page":"25","article-title":"Effects of cryopreservation on the recovery of radiation-induced chromosome aberrations in human lymphocytes","volume":"18","author":"Littlefield L.G.","year":"1987","unstructured":"Littlefield L.G., Joiner E.E., Colyer S.P., Frome E.L. Effects of cryopreservation on the recovery of radiation-induced chromosome aberrations in human lymphocytes. Radiation Protection Dosimetry 1987 c; 18: 25\u201329","journal-title":"Radiation Protection Dosimetry"},{"key":"e_1_2_1_32_1","doi-asserted-by":"publisher","DOI":"10.1080\/09553007514550781"},{"key":"e_1_2_1_33_1","doi-asserted-by":"publisher","DOI":"10.2307\/3576105"},{"key":"e_1_2_1_34_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.116.3007.172"},{"key":"e_1_2_1_35_1","first-page":"339","volume-title":"Radioprotectors and Anticarcinogens","author":"Okada S.","year":"1983","unstructured":"Okada S., Nakamura N., Sakai K. Radioprotection of intracellular genetic material. Radioprotectors and Anticarcinogens, O.F. Nygaard, M.G. Simic. Academic Press, New York 1983; 339\u2013356"},{"key":"e_1_2_1_36_1","doi-asserted-by":"publisher","DOI":"10.1038\/251156a0"},{"key":"e_1_2_1_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/0027-5107(81)90204-9"},{"key":"e_1_2_1_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/0027-5107(79)90134-9"},{"key":"e_1_2_1_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-035404-7.50014-0"},{"key":"e_1_2_1_40_1","doi-asserted-by":"publisher","DOI":"10.1080\/09553007314551431"},{"key":"e_1_2_1_41_1","doi-asserted-by":"publisher","DOI":"10.2307\/3574267"},{"key":"e_1_2_1_42_1","first-page":"329","article-title":"Protection of DNA molecules of cultured mammalian cells from radiation-induced single-strand scissions by various alcohols and SH compounds","volume":"21","author":"Roots S.","year":"1972","unstructured":"Roots S., Okada S. Protection of DNA molecules of cultured mammalian cells from radiation-induced single-strand scissions by various alcohols and SH compounds. International Journal of Radiation Biology 1972; 21: 329\u2013342","journal-title":"International Journal of Radiation Biology"},{"key":"e_1_2_1_43_1","first-page":"439","article-title":"Free radical scavenging in protection of human lymphocytes against chromosome aberration formation by gamma-ray irradiation","volume":"32","author":"Sasaki M.S.","year":"1977","unstructured":"Sasaki M.S., Matsubara S. Free radical scavenging in protection of human lymphocytes against chromosome aberration formation by gamma-ray irradiation. International Journal of Radiation Biology 1977; 32: 439\u2013445","journal-title":"International Journal of Radiation Biology"},{"key":"e_1_2_1_44_1","doi-asserted-by":"publisher","DOI":"10.1101\/SQB.1941.009.01.012"},{"key":"e_1_2_1_45_1","first-page":"129","article-title":"Sites of radiation-induced chromosome exchanges","volume":"6","author":"Savage J.R.K","year":"1970","unstructured":"Savage J.R.K. Sites of radiation-induced chromosome exchanges. Current Topics in Radiation Research 1970; 6: 129\u2013194","journal-title":"Current Topics in Radiation Research"},{"key":"e_1_2_1_46_1","doi-asserted-by":"crossref","unstructured":"Schwartz J.L. Giovanazzi S.M. Grdina D. (1987) 2-[(Aminopropyl)Amino] ethanethiol (WR1065)-mediated reduction in 60Co gamma ray and fission-spectrum neutron-induced chromosome damage in V79 cells. Radiation Research: Proceedings of the 8th International Congress of Radiation Research EdinburghScotland July 1987 E.M. Fielden J.F. Fowler J.H. Hendry D. Scott. Taylor & Francis London 1: 145\u2013145","DOI":"10.2307\/3577187"},{"key":"e_1_2_1_47_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01324376"},{"key":"e_1_2_1_48_1","first-page":"211","article-title":"Effect of L-cysteine on the dose-effect relationship for chromosome aberrations in irradiated human lymphocytes","volume":"42","author":"Virsik R.P.","year":"1982","unstructured":"Virsik R.P., Harder D. Effect of L-cysteine on the dose-effect relationship for chromosome aberrations in irradiated human lymphocytes. International Journal of Radiation Biology 1982; 42: 211\u2013214","journal-title":"International Journal of Radiation Biology"},{"key":"e_1_2_1_49_1","doi-asserted-by":"publisher","DOI":"10.2307\/3575500"},{"key":"e_1_2_1_50_1","doi-asserted-by":"publisher","DOI":"10.2307\/3576637"},{"key":"e_1_2_1_51_1","doi-asserted-by":"publisher","DOI":"10.2307\/3576760"},{"key":"e_1_2_1_52_1","doi-asserted-by":"publisher","DOI":"10.1093\/genetics\/39.3.356"}],"container-title":["International Journal of Radiation Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/09553008814551241","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T16:48:33Z","timestamp":1770914913000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/09553008814551241"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1988,1]]},"references-count":51,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1988,1]]}},"alternative-id":["10.1080\/09553008814551241"],"URL":"https:\/\/doi.org\/10.1080\/09553008814551241","relation":{},"ISSN":["0955-3002","1362-3095"],"issn-type":[{"value":"0955-3002","type":"print"},{"value":"1362-3095","type":"electronic"}],"subject":[],"published":{"date-parts":[[1988,1]]}}}