{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T18:34:38Z","timestamp":1778870078607,"version":"3.51.4"},"reference-count":106,"publisher":"Informa UK Limited","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Radiation Biology"],"published-print":{"date-parts":[[1990,1]]},"DOI":"10.1080\/09553009014552281","type":"journal-article","created":{"date-parts":[[2007,7,26]],"date-time":"2007-07-26T03:58:05Z","timestamp":1185422285000},"page":"925-973","source":"Crossref","is-referenced-by-count":235,"title":["A Comprehensive Study of the Radiobiological Response of the Murine (BDF1) Small Intestine"],"prefix":"10.1080","volume":"58","author":[{"given":"C.S.","family":"Potten","sequence":"first","affiliation":[{"name":"Cancer Research Campaign Department of Epithelial Biology, Paterson Institute for Cancer Research, Christie Hospital and Holt Radium Institute, Manchester, M20 9BX, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2009,7,3]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1007\/BF02889250","article-title":"Cell population kinetics in the mouse jejunal crypt","volume":"18","author":"Al-Dewachi H.S.","year":"1975","unstructured":"Al-Dewachi H.S., Wright N.A., Appleton D.R., Watson A.J. Cell population kinetics in the mouse jejunal crypt. Virchows Archives B, Cell Pathology 1975; 18: 225\u2013242","journal-title":"Virchows Archives B, Cell Pathology"},{"key":"e_1_2_1_3_1","first-page":"203","article-title":"The effect of a single injection of hydroxyurea on cell population kinetics in the small bowel mucosa of the rat","volume":"10","author":"Al-Dewachi H.S.","year":"1977","unstructured":"Al-Dewachi H.S., Wright N.A., Appleton D.R., Watson A.J. The effect of a single injection of hydroxyurea on cell population kinetics in the small bowel mucosa of the rat. Cell and Tissue Kinetics 1977; 10: 203\u2013213","journal-title":"Cell and Tissue Kinetics"},{"key":"e_1_2_1_4_1","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/BF02889921","article-title":"Variation in the cell cycle time in the crypts of Lieberkuhn of the mouse","volume":"31","author":"Al-Dewachi H.S.","year":"1979","unstructured":"Al-Dewachi H.S., Appleton D.R., Watson A.J., Wright N.A. Variation in the cell cycle time in the crypts of Lieberkuhn of the mouse. Virchows Archives B, Cell Pathology 1979; 31: 37\u201344","journal-title":"Virchows Archives B, Cell Pathology"},{"key":"e_1_2_1_5_1","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1007\/BF02892427","article-title":"The effects of a single injection of cytosine arabinoside on cell population kinetics in the mouse jejunal crypt","volume":"34","author":"Al-Dewachi H.S.","year":"1980","unstructured":"Al-Dewachi H.S., Wright N.A., Appleton D.R., Watson A.J. The effects of a single injection of cytosine arabinoside on cell population kinetics in the mouse jejunal crypt. Virchows Archives B, Cell Pathology 1980; 34: 299\u2013309","journal-title":"Virchows Archives B, Cell Pathology"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.3109\/02841868209134001"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.3109\/02841868309134046"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1001600105"},{"key":"e_1_2_1_9_1","first-page":"589","article-title":"The proliferative status of intestinal epithelial clonogenic cells: sensitivity to S-phase specific cytotoxic agents","volume":"9","author":"Boarder T.A.","year":"1976","unstructured":"Boarder T.A., Blackett N.M. The proliferative status of intestinal epithelial clonogenic cells: sensitivity to S-phase specific cytotoxic agents. Cell and Tissue Kinetics 1976; 9: 589\u2013596","journal-title":"Cell and Tissue Kinetics"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.2307\/3572221"},{"key":"e_1_2_1_11_1","doi-asserted-by":"crossref","first-page":"82","DOI":"10.2307\/3572712","article-title":"Further studies on the response of the small intestine to continuous irradiation","volume":"38","author":"Cairnie A.B","year":"1969","unstructured":"Cairnie A.B. Further studies on the response of the small intestine to continuous irradiation. Radiation Research 1969; 38: 82\u201394","journal-title":"Radiation Research"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4827(65)90055-8"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4827(65)90056-X"},{"key":"e_1_2_1_14_1","first-page":"189","article-title":"Fission of crypts in the small intestine of the irradiated mouse","volume":"8","author":"Cairnie A.B.","year":"1975","unstructured":"Cairnie A.B., Millen B.H. Fission of crypts in the small intestine of the irradiated mouse. Cell and Tissue Kinetics 1975; 8: 189\u2013196","journal-title":"Cell and Tissue Kinetics"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1001410407"},{"key":"e_1_2_1_16_1","first-page":"809","article-title":"Radiation induced mitotic delay: duration, dose and cell position dependence in the crypts of the small intestine in the mouse","volume":"49","author":"Chwalinski S.","year":"1986","unstructured":"Chwalinski S., Potten C.S. Radiation induced mitotic delay: duration, dose and cell position dependence in the crypts of the small intestine in the mouse. International Journal of Radiation Biology 1986; 49: 809\u2013819","journal-title":"International Journal of Radiation Biology"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1001860409"},{"key":"e_1_2_1_18_1","doi-asserted-by":"crossref","DOI":"10.1111\/j.1365-2184.1991.tb01508.x","article-title":"The decay of autoradiographic grain number over crypt base columnar cells in murine ileum as a measure of their generation time","author":"Chwalinski S.","year":"1991","unstructured":"Chwalinski, S., Potten, C.S. The decay of autoradiographic grain number over crypt base columnar cells in murine ileum as a measure of their generation time. Cell Proliferation, in press, 1991","journal-title":"Cell Proliferation"},{"key":"e_1_2_1_19_1","first-page":"317","article-title":"Double labelling with bromodeoxyuridine (BrdUrd) and 3Hthymidine (3HTdR) of proliferative cells in small intestinal epithelium in steady state and after irradiation","volume":"21","author":"Chwalinski S.","year":"1988","unstructured":"Chwalinski S., Potten C.S., Evans G. Double labelling with bromodeoxyuridine (BrdUrd) and 3Hthymidine (3HTdR) of proliferative cells in small intestinal epithelium in steady state and after irradiation. Cell and Tissue Kinetics 1988; 21: 317\u2013329","journal-title":"Cell and Tissue Kinetics"},{"key":"e_1_2_1_20_1","first-page":"129","article-title":"Intestinal cell kinetics in irradiated mice. A quantitative investigation of the acute reaction to whole body roentgen irradiation","volume":"10","author":"Devik F","year":"1971","unstructured":"Devik F. Intestinal cell kinetics in irradiated mice. A quantitative investigation of the acute reaction to whole body roentgen irradiation. Acta Radiologica 1971; 10: 129\u2013149","journal-title":"Acta Radiologica"},{"key":"e_1_2_1_21_1","first-page":"705","article-title":"Radiation response of mammalian cells grown in culture. IV. Dose dependence of division delay and post-irradiation growth of surviving and non-surviving Chinese hamster cells","volume":"30","author":"Elkind M.M.","year":"1963","unstructured":"Elkind M.M., Han A., Volz K.W. Radiation response of mammalian cells grown in culture. IV. Dose dependence of division delay and post-irradiation growth of surviving and non-surviving Chinese hamster cells. Journal of the National Cancer Institute 1963; 30: 705\u2013721","journal-title":"Journal of the National Cancer Institute"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.2307\/3577660"},{"key":"e_1_2_1_23_1","first-page":"53","article-title":"The labelled mitosis curve and the estimation of the parameters of the cell cycle","volume":"5","author":"Gilbert C.S","year":"1972","unstructured":"Gilbert C.S. The labelled mitosis curve and the estimation of the parameters of the cell cycle. Cell and Tissue Kinetics 1972; 5: 53\u201363","journal-title":"Cell and Tissue Kinetics"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/333461a0"},{"key":"e_1_2_1_25_1","first-page":"3","article-title":"Fasting and refeeding: cell kinetics response of jejunum ileum and colon","volume":"10","author":"Hagemann R.F.","year":"1977","unstructured":"Hagemann R.F., Stragand J.J. Fasting and refeeding: cell kinetics response of jejunum ileum and colon. Cell and Tissue Kinetics 1977; 10: 3\u201314","journal-title":"Cell and Tissue Kinetics"},{"key":"e_1_2_1_26_1","first-page":"291","article-title":"Radiation LD50\/5 and its relation to surviving intestinal stem cells","volume":"16","author":"Hagemann R.F.","year":"1969","unstructured":"Hagemann R.F., Sigdestad C.P., Lesher S. Radiation LD50\/5 and its relation to surviving intestinal stem cells. International Journal of Radiation Biology 1969; 16: 291\u2013292","journal-title":"International Journal of Radiation Biology"},{"key":"e_1_2_1_27_1","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1002\/aja.1001290104","article-title":"A quantitative description of the intestinal epithelium of the mouse","volume":"129","author":"Hagemann R.F.","year":"1970","unstructured":"Hagemann R.F., Sigdestad C.P., Lesher S. A quantitative description of the intestinal epithelium of the mouse. American Journal of Anatomy 1970a; 129: 41\u201352","journal-title":"American Journal of Anatomy"},{"key":"e_1_2_1_28_1","first-page":"21","article-title":"A method for quantitation of proliferative intestinal mucosal cells on a weight basis: some values for C57B1\/6","volume":"3","author":"Hagemann R.F.","year":"1970","unstructured":"Hagemann R.F., Sigdestad C.P., Lesher S. A method for quantitation of proliferative intestinal mucosal cells on a weight basis: some values for C57B1\/6. Cell and Tissue Kinetics 1970a; 3: 21\u201326","journal-title":"Cell and Tissue Kinetics"},{"key":"e_1_2_1_29_1","first-page":"423","article-title":"Cell proliferation and ageing in mouse colon. I. Repopulation after repeated X-ray injury in young and old mice","volume":"11","author":"Hamilton E","year":"1978","unstructured":"Hamilton E. Cell proliferation and ageing in mouse colon. I. Repopulation after repeated X-ray injury in young and old mice. Cell and Tissue Kinetics 1978; 11: 423\u2013431","journal-title":"Cell and Tissue Kinetics"},{"key":"e_1_2_1_30_1","first-page":"91","article-title":"Diurnal variation in proliferative compartments and their relation to cryptogenic cells in the mouse colon","volume":"12","author":"Hamilton E","year":"1979","unstructured":"Hamilton E. Diurnal variation in proliferative compartments and their relation to cryptogenic cells in the mouse colon. Cell and Tissue Kinetics 1979a; 12: 91\u2013100","journal-title":"Cell and Tissue Kinetics"},{"key":"e_1_2_1_31_1","first-page":"537","article-title":"Induction of radioresistance in mouse colon crypts by X-rays","volume":"36","author":"Hamilton E","year":"1979","unstructured":"Hamilton E. Induction of radioresistance in mouse colon crypts by X-rays. International Journal of Radiation Biology 1979b; 36: 537\u2013545","journal-title":"International Journal of Radiation Biology"},{"key":"e_1_2_1_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-2964(80)90207-8"},{"key":"e_1_2_1_33_1","first-page":"13","volume-title":"Gastrointestinal Radiation Injury","author":"Hampton J.C","year":"1968","unstructured":"Hampton J.C. Gastrointestinal Radiation Injury, M.F. Sullivan. Excerpta Medica, Amsterdam 1968; 13\u201326, In"},{"key":"e_1_2_1_34_1","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/0360-3016(83)90070-6","article-title":"Cytosar-U (ARA-C) induced changes in mouse jejunal crypt epithelial kinetics and radiosensitivity to gamma rays and fast neutrons","volume":"9","author":"Hanson W.R.","year":"1983","unstructured":"Hanson W.R., Boston D.L. Cytosar-U (ARA-C) induced changes in mouse jejunal crypt epithelial kinetics and radiosensitivity to gamma rays and fast neutrons. International Journal of Radiation Oncology, Biology, Physics 1983; 9: 515\u2013521","journal-title":"International Journal of Radiation Oncology, Biology, Physics"},{"key":"e_1_2_1_35_1","first-page":"198","volume-title":"Cell Proliferation in the Gastrointestinal Tract","author":"Hanson W.R.","year":"1980","unstructured":"Hanson W.R., Henninger D.L., Fry R.J.M., Sallese A.R. The response of small intestinal stem cells in the mouse to drug and irradiation treatment. Cell Proliferation in the Gastrointestinal Tract, D.R. Appleton, J.P. Sunter, A.J. Watson. Pitman Medical, Tunbridge Wells. 1980; 198\u2013212"},{"key":"e_1_2_1_36_1","doi-asserted-by":"publisher","DOI":"10.1259\/0007-1285-48-568-312"},{"key":"e_1_2_1_37_1","doi-asserted-by":"publisher","DOI":"10.2307\/3574968"},{"key":"e_1_2_1_38_1","first-page":"583","article-title":"Cryptogenic cells and proliferative cells in intestinal epithelium","volume":"25","author":"Hendry J.H.","year":"1974","unstructured":"Hendry J.H., Potten C.S. Cryptogenic cells and proliferative cells in intestinal epithelium. International Journal of Radiation Biology 1974; 25: 583\u2013588","journal-title":"International Journal of Radiation Biology"},{"key":"e_1_2_1_39_1","first-page":"621","article-title":"Intestinal cell radiosensitivity: a comparison for cell death assayed by apoptosis or by a loss of clonogenicity","volume":"42","author":"Hendry J.H.","year":"1982","unstructured":"Hendry J.H., Potten C.S. Intestinal cell radiosensitivity: a comparison for cell death assayed by apoptosis or by a loss of clonogenicity. International Journal of Radiation Biology 1982; 42: 621\u2013628","journal-title":"International Journal of Radiation Biology"},{"key":"e_1_2_1_40_1","first-page":"41","article-title":"The proliferative status of microcolony-forming cells in mouse small intestine","volume":"17","author":"Hendry J.H.","year":"1984","unstructured":"Hendry J.H., Moore J.V., Potten C.S. The proliferative status of microcolony-forming cells in mouse small intestine. Cell and Tissue Kinetics 1984; 17: 41\u201347","journal-title":"Cell and Tissue Kinetics"},{"key":"e_1_2_1_41_1","first-page":"611","article-title":"Cell death (apoptosis) in the mouse small intestine after low doses: effects of dose-rate 14\u00b77 MeV neutrons and 600 MeV (maximum energy) neutrons","volume":"42","author":"Hendry J.H.","year":"1982","unstructured":"Hendry J.H., Potten C.S., Chadwick C., Bianchi M. Cell death (apoptosis) in the mouse small intestine after low doses: effects of dose-rate 14\u00b77 MeV neutrons and 600 MeV (maximum energy) neutrons. International Journal of Radiation Biology 1982; 42: 611\u2013620","journal-title":"International Journal of Radiation Biology"},{"key":"e_1_2_1_42_1","doi-asserted-by":"publisher","DOI":"10.2307\/3577450"},{"key":"e_1_2_1_43_1","doi-asserted-by":"crossref","first-page":"110","DOI":"10.2307\/3576169","article-title":"The gastrointestinal syndrome and mucosal clonogenic cells: relationships between target cell sensitivites, LD50 and cell survival, and their modification by antibiotics","volume":"96","author":"Hendry J.H.","year":"1983","unstructured":"Hendry J.H., Potten C.S., Roberts N.P. The gastrointestinal syndrome and mucosal clonogenic cells: relationships between target cell sensitivites, LD50 and cell survival, and their modification by antibiotics. Radiation Research 1983; 96: 110\u2013112","journal-title":"Radiation Research"},{"key":"e_1_2_1_44_1","doi-asserted-by":"publisher","DOI":"10.2307\/3575138"},{"key":"e_1_2_1_45_1","first-page":"91","article-title":"Proliferation studies of the endothelial and smooth muscle cells of the mouse mesentery after irradiation","volume":"13","author":"Hirst D.G.","year":"1980","unstructured":"Hirst D.G., Denekamp J., Hobson B. Proliferation studies of the endothelial and smooth muscle cells of the mouse mesentery after irradiation. Cell and Tissue Kinetics 1980; 13: 91\u2013104","journal-title":"Cell and Tissue Kinetics"},{"key":"e_1_2_1_46_1","doi-asserted-by":"publisher","DOI":"10.2307\/3573811"},{"key":"e_1_2_1_47_1","first-page":"44","volume-title":"Cell Clones","author":"Hornsey S","year":"1985","unstructured":"Hornsey S. The macrocolony assay in small intestine. Cell Clones, C.S. Potten, J.H. Hendry. Churchill-Livingstone, Edinburgh 1985; 44\u201349"},{"key":"e_1_2_1_48_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1983.25"},{"key":"e_1_2_1_49_1","first-page":"609","article-title":"The re-establishment of hypersensitive cells in the crypts of irradiated mouse intestine","volume":"46","author":"Ijiri K.","year":"1984","unstructured":"Ijiri K., Potten C.S. The re-establishment of hypersensitive cells in the crypts of irradiated mouse intestine. International Journal of Radiation Biology 1984; 46: 609\u2013624","journal-title":"International Journal of Radiation Biology"},{"issue":"7","key":"e_1_2_1_50_1","first-page":"20","article-title":"Radiation hypersensitive cells in small intestinal crypts; their relationships to clonogenic cells","volume":"53","author":"Ijiri K.","year":"1986","unstructured":"Ijiri K., Potten C.S. Radiation hypersensitive cells in small intestinal crypts; their relationships to clonogenic cells. British Journal of Cancer 1986; 53(Suppl. 7)20\u201322","journal-title":"British Journal of Cancer"},{"key":"e_1_2_1_51_1","first-page":"326","volume-title":"Perspectives on Mammalian Cell Death","author":"Ijiri K.","year":"1987","unstructured":"Ijiri K., Potten C.S. Cell death in cell hierarchies in adult mammalian tissues. Perspectives on Mammalian Cell Death, C.S. Potten. Oxford University Press, Oxford 1987a; 326\u2013356"},{"key":"e_1_2_1_52_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1987.25"},{"key":"e_1_2_1_53_1","doi-asserted-by":"publisher","DOI":"10.1080\/09553008814551091"},{"key":"e_1_2_1_54_1","doi-asserted-by":"publisher","DOI":"10.1080\/09553009014551521"},{"key":"e_1_2_1_55_1","article-title":"Circadian rhythms in the response of murine intestinal crypt cells to cytotoxic drugs","author":"Ijiri K.","year":"1990","unstructured":"Ijiri, K., Potten, C.S. Circadian rhythms in the response of murine intestinal crypt cells to cytotoxic drugs. International Journal of Radiation Biology, in press, 1990b","journal-title":"International Journal of Radiation Biology"},{"key":"e_1_2_1_56_1","first-page":"49","article-title":"Macroscopic intestinal colonies of mice as a tool for studying differentiation of multipotential intestinal stem cells","volume":"132","author":"Inoue M.","year":"1988","unstructured":"Inoue M., Imada M., Fukushima Y., Matsuura N., Shiozaki H., Mori T., Kitamura Y., Fujita H. Macroscopic intestinal colonies of mice as a tool for studying differentiation of multipotential intestinal stem cells. American Journal of Pathology 1988; 132: 49\u201358","journal-title":"American Journal of Pathology"},{"key":"e_1_2_1_57_1","first-page":"591","article-title":"Circadian variation in migration in small intestinal epithelium","volume":"19","author":"Kaur P.","year":"1986","unstructured":"Kaur P., Potten C.S. Circadian variation in migration in small intestinal epithelium. Cell and Tissue Kinetics 1986a; 19: 591\u2013600","journal-title":"Cell and Tissue Kinetics"},{"key":"e_1_2_1_58_1","first-page":"601","article-title":"Cell migration velocities in the crypts after cytotoxic insult are not dependent on mitotic activity","volume":"19","author":"Kaur P.","year":"1986","unstructured":"Kaur P., Potten C.S. Cell migration velocities in the crypts after cytotoxic insult are not dependent on mitotic activity. Cell and Tissue Kinetics 1986b; 19: 601\u2013610","journal-title":"Cell and Tissue Kinetics"},{"key":"e_1_2_1_59_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1972.33"},{"key":"e_1_2_1_60_1","first-page":"125","article-title":"An estimation of proliferative population size in stomach, jejunum and colon of DBA-2 mice","volume":"6","author":"Kovacs L.","year":"1973","unstructured":"Kovacs L., Potten C.S. An estimation of proliferative population size in stomach, jejunum and colon of DBA-2 mice. Cell and Tissue Kinetics 1973; 6: 125\u2013134","journal-title":"Cell and Tissue Kinetics"},{"key":"e_1_2_1_61_1","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/B978-0-12-155050-9.50008-0","volume-title":"Stem Cells of Renewing Cell Populations","author":"Leblond C.P.","year":"1976","unstructured":"Leblond, C.P., Cheng, H. Identification of stem cells in the small intestine of the mouse. Stem Cells of Renewing Cell Populations, A.B. Cairnie, et al. Academic Press, New York 1976; 7\u201331"},{"key":"e_1_2_1_62_1","doi-asserted-by":"publisher","DOI":"10.2307\/3572263"},{"key":"e_1_2_1_63_1","first-page":"627","article-title":"Intestinal cell proliferation. I. A comprehensive model of steady state proliferation in the crypt","volume":"19","author":"Loeffler M.R.","year":"1986","unstructured":"Loeffler M.R., Stein R., Wichmann H.E., Potten C.S., Kaur P., Chwalinski S. Intestinal cell proliferation. I. A comprehensive model of steady state proliferation in the crypt. Cell and Tissue Kinetics 1986; 19: 627\u2013646","journal-title":"Cell and Tissue Kinetics"},{"key":"e_1_2_1_64_1","first-page":"247","article-title":"Intestinal crypt proliferation. II. Computer modelling of mitotic index data provides further evidence for lateral and vertical cell migration in the absence of mitotic activity","volume":"21","author":"Loeffler M.","year":"1988","unstructured":"Loeffler M., Potten C.S., Glatzer J., Chwalinski S. Intestinal crypt proliferation. II. Computer modelling of mitotic index data provides further evidence for lateral and vertical cell migration in the absence of mitotic activity. Cell and Tissue Kinetics 1988; 21: 247\u2013258","journal-title":"Cell and Tissue Kinetics"},{"key":"e_1_2_1_65_1","first-page":"255","article-title":"Radiobiology and stathmokinetics of intestinal crypts associated with patches of Peyer","volume":"51","author":"Maunda K.K.Y.","year":"1987","unstructured":"Maunda K.K.Y., Moore J.V. Radiobiology and stathmokinetics of intestinal crypts associated with patches of Peyer. International Journal of Radiation Biology 1987; 51: 255\u2013261","journal-title":"International Journal of Radiation Biology"},{"key":"e_1_2_1_66_1","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1038\/bjc.1979.28","article-title":"Ablation of murine jejunal crypts by alkylating agents","volume":"39","author":"Moore J.V","year":"1979","unstructured":"Moore J.V. Ablation of murine jejunal crypts by alkylating agents. British Journal of Cancer 1979; 39: 175\u2013181","journal-title":"British Journal of Cancer"},{"key":"e_1_2_1_67_1","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1038\/bjc.1984.5","article-title":"Death of intestinal crypts and of their constituent cells after treatment by chemotherapeutic drugs","volume":"49","author":"Moore J.V","year":"1984","unstructured":"Moore J.V. Death of intestinal crypts and of their constituent cells after treatment by chemotherapeutic drugs. British Journal of Cancer 1984; 49: 25\u201332","journal-title":"British Journal of Cancer"},{"key":"e_1_2_1_68_1","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/BF00257286","article-title":"Clonogenic response of cells of murine intestinal crypts to 12 cytotoxic drugs","volume":"15","author":"Moore J.V","year":"1985","unstructured":"Moore J.V. Clonogenic response of cells of murine intestinal crypts to 12 cytotoxic drugs. Cancer Chemotherapy Pharmacology 1985; 15: 11\u201315","journal-title":"Cancer Chemotherapy Pharmacology"},{"key":"e_1_2_1_69_1","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1038\/bjc.1980.303","article-title":"Survival of intestinal crypts after treatment by adriamycin alone or with radiation","volume":"42","author":"Moore J.V.","year":"1980","unstructured":"Moore J.V., Broadbent D.A. Survival of intestinal crypts after treatment by adriamycin alone or with radiation. British Journal of Cancer 1980; 42: 692\u2013696","journal-title":"British Journal of Cancer"},{"key":"e_1_2_1_70_1","doi-asserted-by":"publisher","DOI":"10.1259\/0007-1285-56-663-193"},{"key":"e_1_2_1_71_1","first-page":"175","article-title":"Effect of low-dose ionizing radiation on the murine pericryptal fibroblast sheath: radiation damage in a mesenchymal system in vivo","volume":"39","author":"Neal J.V.","year":"1981","unstructured":"Neal J.V., Potten C.S. Effect of low-dose ionizing radiation on the murine pericryptal fibroblast sheath: radiation damage in a mesenchymal system in vivo. International Journal of Radiation Biology 1981; 39: 175\u2013183","journal-title":"International Journal of Radiation Biology"},{"key":"e_1_2_1_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/0012-1606(83)90191-4"},{"key":"e_1_2_1_73_1","doi-asserted-by":"publisher","DOI":"10.1038\/313689a0"},{"key":"e_1_2_1_74_1","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/B978-0-12-155050-9.50013-4","volume-title":"Stem Cells of Renewing Cell Populations","author":"Potten C.S","year":"1976","unstructured":"Potten, C.S. Small intestinal crypt stem cells. Stem Cells of Renewing Cell Populations, A.B. Cairnie, et al. Academic Press, New York 1976; 79\u201384"},{"key":"e_1_2_1_75_1","doi-asserted-by":"publisher","DOI":"10.1038\/269518a0"},{"key":"e_1_2_1_76_1","first-page":"381","volume-title":"Tumor Viruses and Differentiation","author":"Potten C.S","year":"1983","unstructured":"Potten C.S. Stem cells in gastrointestinal mucosa. Tumor Viruses and Differentiation, E.M. Solnick, A.J. Levine. Alan R. Liss, New York 1983; 381\u2013389"},{"key":"e_1_2_1_77_1","first-page":"257","article-title":"Cell cycles in cell hierarchies","volume":"49","author":"Potten C.S","year":"1986","unstructured":"Potten C.S. Cell cycles in cell hierarchies. International Journal of Radiation Biology 1986; 49: 257\u2013278","journal-title":"International Journal of Radiation Biology"},{"key":"e_1_2_1_78_1","first-page":"557","article-title":"Circadian rhythms of presumptive stem cells in three different epithelia of the mouse","volume":"10","author":"Potten C.S.","year":"1977","unstructured":"Potten C.S., Al-Barwari S.E., Hume W.J., Searle J. Circadian rhythms of presumptive stem cells in three different epithelia of the mouse. Cell and Tissue Kinetics 1977; 10: 557\u2013568","journal-title":"Cell and Tissue Kinetics"},{"key":"e_1_2_1_79_1","doi-asserted-by":"publisher","DOI":"10.1002\/stem.5530020206"},{"key":"e_1_2_1_80_1","first-page":"285","volume-title":"The Functional Integration of Cells in Animal Tissues","author":"Potten C.S.","year":"1982","unstructured":"Potten C.S., Chwalinski S., Khokaar M.T. Spatial inter-relationships in surface epithelia: their significance in proliferation control. The Functional Integration of Cells in Animal Tissues, J.D. Pitts, M.E. Finbow. Cambridge University Press, Cambridge 1982a; 285\u2013300"},{"key":"e_1_2_1_81_1","first-page":"351","article-title":"The spatial organisation of the hierarchical proliferative cells of the small intestine into clusters of \u2018synchronised\u2019 cells","volume":"15","author":"Potten C.S.","year":"1982","unstructured":"Potten C.S., Chwalinski S., Swindell R., Palmer M. The spatial organisation of the hierarchical proliferative cells of the small intestine into clusters of \u2018synchronised\u2019 cells. Cell and Tissue Kinetics 1982b; 15: 351\u2013370","journal-title":"Cell and Tissue Kinetics"},{"key":"e_1_2_1_82_1","doi-asserted-by":"publisher","DOI":"10.1080\/09553009014550301"},{"key":"e_1_2_1_83_1","first-page":"413","article-title":"Differential regeneration of intestinal proliferative cells and cryptogenics cells after irradiation","volume":"27","author":"Potten C.S.","year":"1975","unstructured":"Potten C.S., Hendry J.H. Differential regeneration of intestinal proliferative cells and cryptogenics cells after irradiation. International Journal of Radiation Biology 1975; 27: 413\u2013424","journal-title":"International Journal of Radiation Biology"},{"key":"e_1_2_1_84_1","first-page":"155","volume-title":"Stem Cells: their Identification and Characterisation","author":"Potten C.S.","year":"1983","unstructured":"Potten C.S., Hendry J.H. Stem cells in murine small intestine. Stem Cells: their Identification and Characterisation, C.S. Potten. Churchill-Livingstone, Edinbrugh 1983; 155\u2013159"},{"key":"e_1_2_1_85_1","first-page":"50","volume-title":"Cell Clones: Manual of Mammalian Cell Techniques","author":"Potten C.S.","year":"1985","unstructured":"Potten C.S., Hendry J.H. The microcolony assay in mouse small intestine. Cell Clones: Manual of Mammalian Cell Techniques, C.S. Potten, J.H. Hendry. Churchill-Livingstone, Edinburgh 1985; 50\u201360"},{"key":"e_1_2_1_86_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02890247"},{"key":"e_1_2_1_87_1","first-page":"105","volume-title":"Cytotoxic Insult to Tissue: Effects on Cell Lineages","author":"Potten C.S.","year":"1983","unstructured":"Potten C.S., Hendry J.H., Moore J.V., Chwalinski S. Cytotoxic effects in gastro-intestinal epithelium (as exemplified by small intestine). Cytotoxic Insult to Tissue: Effects on Cell Lineages, C.S. Potten, J.H. Hendry. Churchill-Livingstone, Edinburgh 1983; 105\u2013152"},{"key":"e_1_2_1_88_1","first-page":"1041","article-title":"The doubling time of regenerating clonogenic cells in the crypts of the small intestine","volume":"54","author":"Potten C.S.","year":"1988","unstructured":"Potten C.S., Hendry J.H., Taylor Y. The doubling time of regenerating clonogenic cells in the crypts of the small intestine. International Journal of Radiology 1988b; 54: 1041\u20131051","journal-title":"International Journal of Radiology"},{"key":"e_1_2_1_89_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-5193(87)80136-4"},{"key":"e_1_2_1_90_1","article-title":"Stem cells: attributes, cycles, spirals, pitfalls and uncertainties","author":"Potten C.S.","year":"1990","unstructured":"Potten, C.S., Loeffler, M. Stem cells: attributes, cycles, spirals, pitfalls and uncertainties. Development, in press, 1990","journal-title":"Development"},{"key":"e_1_2_1_91_1","doi-asserted-by":"publisher","DOI":"10.1080\/09553009014550431"},{"key":"e_1_2_1_92_1","first-page":"321","article-title":"The correction of intestinal microcology counts for variation in size","volume":"40","author":"Potten C.S.","year":"1981","unstructured":"Potten C.S., Rezvani M., Hendry J.H., Moore J.V., Major D. The correction of intestinal microcology counts for variation in size. International Journal of Radiation Biology 1981; 40: 321\u2013326","journal-title":"International Journal of Radiation Biology"},{"key":"e_1_2_1_93_1","first-page":"231","article-title":"The reliability in scoring mitotic activity in longitudinal crypts of the small sections of intestine","volume":"21","author":"Potten C.S.","year":"1988","unstructured":"Potten C.S., Roberts S.A., Chwalinski S., Loeffler M., Paulus U. The reliability in scoring mitotic activity in longitudinal crypts of the small sections of intestine. Cell and Tissue Kinetics 1988a; 21: 231\u2013246","journal-title":"Cell and Tissue Kinetics"},{"key":"e_1_2_1_94_1","first-page":"305","article-title":"Evidence for discrete cell kinetic sub-populations in mouse epidermis based on mathematical analysis","volume":"15","author":"Potten C.S.","year":"1982","unstructured":"Potten C.S., Wichmann H.E., Loeffler M., Dobek K., Major D. Evidence for discrete cell kinetic sub-populations in mouse epidermis based on mathematical analysis. Cell and Tissue Kinetics 1982; 15: 305\u2013329","journal-title":"Cell and Tissue Kinetics"},{"key":"e_1_2_1_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4827(59)90063-1"},{"key":"e_1_2_1_96_1","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(81)90091-2"},{"key":"e_1_2_1_97_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(87)83215-0"},{"key":"e_1_2_1_98_1","first-page":"361","article-title":"Recruitment of cells in the small intestines into rapid cell cycle by small doses of external or internal radiation","volume":"48","author":"Tsubouchi S.","year":"1985","unstructured":"Tsubouchi S., Potten C.S. Recruitment of cells in the small intestines into rapid cell cycle by small doses of external or internal radiation. International Journal of Radiation Biology 1985; 48: 361\u2013369","journal-title":"International Journal of Radiation Biology"},{"key":"e_1_2_1_99_1","first-page":"59","article-title":"Studies on structure and function of the mucosal microvascular system of the gastrointestinal tract with special references to their relations to epithelial functions","volume":"92","author":"Tsuchihashi Y","year":"1983","unstructured":"Tsuchihashi Y. Studies on structure and function of the mucosal microvascular system of the gastrointestinal tract with special references to their relations to epithelial functions. Journal of the Kyoto Prefecture University of Medicine 1983; 92: 59\u201381, (in Japanese with English abstract)","journal-title":"Journal of the Kyoto Prefecture University of Medicine"},{"key":"e_1_2_1_100_1","article-title":"Probability of self-renewing divisions of sperhatogonial stem cells in colonies formed after fission neutron irradiation","volume":"22","author":"Van Beek M.E.A.B.","year":"1989","unstructured":"Van Beek, M.E.A.B., Meistrich, M.L., de Rooij, D.G. Probability of self-renewing divisions of sperhatogonial stem cells in colonies formed after fission neutron irradiation. Cell and Tissue Kinetics, in press, 1989; 22","journal-title":"Cell and Tissue Kinetics"},{"key":"e_1_2_1_101_1","doi-asserted-by":"publisher","DOI":"10.1038\/333463a0"},{"key":"e_1_2_1_102_1","doi-asserted-by":"publisher","DOI":"10.1093\/mutage\/4.5.404"},{"key":"e_1_2_1_103_1","doi-asserted-by":"publisher","DOI":"10.1148\/91.5.998"},{"key":"e_1_2_1_104_1","doi-asserted-by":"publisher","DOI":"10.2307\/3572619"},{"key":"e_1_2_1_105_1","first-page":"261","article-title":"Microcolony survival assay for cells of mouse intestinal mucosa exposed to radiation","volume":"17","author":"Withers H.R.","year":"1970","unstructured":"Withers H.R., Elkind M.M. Microcolony survival assay for cells of mouse intestinal mucosa exposed to radiation. International Journal of Radiation Biology 1970; 17: 261\u2013268","journal-title":"International Journal of Radiation Biology"},{"key":"e_1_2_1_106_1","first-page":"539","volume-title":"The Biology of Epithelial Cell Populations","author":"Wright N.A.","year":"1984","unstructured":"Wright N.A., Alison M. The Biology of Epithelial Cell Populations. Clarendon Press, Oxford 1984; 2: 539\u20131247"},{"key":"e_1_2_1_107_1","first-page":"63","article-title":"Response of mouse intestine to 14 MeV neutrons","volume":"35","author":"Zywietz F.","year":"1979","unstructured":"Zywietz F., Jung H., Hess A., Franke H.D. Response of mouse intestine to 14 MeV neutrons. International Journal of Radiation Biology 1979; 35: 63\u201372","journal-title":"International Journal of Radiation Biology"}],"container-title":["International Journal of Radiation Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/09553009014552281","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T23:49:00Z","timestamp":1770940140000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/09553009014552281"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,1]]},"references-count":106,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1990,1]]}},"alternative-id":["10.1080\/09553009014552281"],"URL":"https:\/\/doi.org\/10.1080\/09553009014552281","relation":{},"ISSN":["0955-3002","1362-3095"],"issn-type":[{"value":"0955-3002","type":"print"},{"value":"1362-3095","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,1]]}}}