{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T22:26:06Z","timestamp":1793658366680,"version":"4.5.1"},"reference-count":97,"publisher":"Informa UK Limited","issue":"20","license":[{"start":{"date-parts":[[2021,12,6]],"date-time":"2021-12-06T00:00:00Z","timestamp":1638748800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1080\/policies-text-data-mining"}],"funder":[{"name":"Shandong Provincial Natural Science Foundation","award":["ZR2019MH020"],"award-info":[{"award-number":["ZR2019MH020"]}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Critical Reviews in Food Science and Nutrition"],"published-print":{"date-parts":[[2023,8,7]]},"DOI":"10.1080\/10408398.2021.2006137","type":"journal-article","created":{"date-parts":[[2021,12,6]],"date-time":"2021-12-06T12:07:56Z","timestamp":1638792476000},"page":"4675-4686","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":14,"title":["Phytosterols as bioactive food components against nonalcoholic fatty liver disease"],"prefix":"10.1080","volume":"63","author":[{"given":"Jing-Wen","family":"Yang","sequence":"first","affiliation":[{"name":"Institute of Biomedical Research, Shandong University of Technology","place":["Zibo, People\u2019s Republic of China"]},{"name":"Shandong Provincial Research Center for Bioinformatic Engineering and Technique, Zibo Key Laboratory of New Drug Development of Neurodegenerative diseases, School of Life Sciences, Shandong University of Technology","place":["Zibo, People\u2019s Republic of China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong-Fang","family":"Ji","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Research, Shandong University of Technology","place":["Zibo, People\u2019s Republic of China"]},{"name":"Shandong Provincial Research Center for Bioinformatic Engineering and Technique, Zibo Key Laboratory of New Drug Development of Neurodegenerative diseases, School of Life Sciences, Shandong University of Technology","place":["Zibo, People\u2019s Republic of China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2021,12,6]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0523.2008.01531.x"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2017.10.018"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2015.05.015"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41575-020-0269-9"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.plefa.2003.11.005"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M704391200"},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2005.08.024"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20734"},{"key":"e_1_3_2_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2275(20)38881-7"},{"key":"e_1_3_2_11_1","doi-asserted-by":"publisher","DOI":"10.3945\/jn.111.157198"},{"key":"e_1_3_2_12_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0021576"},{"key":"e_1_3_2_13_1","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.M700470-JLR200"},{"key":"e_1_3_2_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2008.07.048"},{"key":"e_1_3_2_15_1","doi-asserted-by":"publisher","DOI":"10.1203\/PDR.0b013e3181256492"},{"key":"e_1_3_2_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.201700055"},{"key":"e_1_3_2_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2275(20)37835-4"},{"key":"e_1_3_2_18_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M803702200"},{"key":"e_1_3_2_19_1","doi-asserted-by":"publisher","DOI":"10.1017\/S000711451400350X"},{"key":"e_1_3_2_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.201100722"},{"key":"e_1_3_2_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00394-011-0297-x"},{"key":"e_1_3_2_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.alcohol.2006.12.006"},{"key":"e_1_3_2_23_1","doi-asserted-by":"publisher","DOI":"10.1159\/000479734"},{"issue":"34","key":"e_1_3_2_24_1","first-page":"5077","article-title":"The lipid-lowering effects and associated mechanisms of dietary phytosterol supplementation","volume":"23","author":"Dumolt J. H.","year":"2017","unstructured":"Dumolt, J. H., and T. C. Rideout. 2017. The lipid-lowering effects and associated mechanisms of dietary phytosterol supplementation. Current Pharmaceutical Design 23 (34):5077\u201385.","journal-title":"Current Pharmaceutical Design"},{"key":"e_1_3_2_25_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13073-015-0179-6"},{"key":"e_1_3_2_26_1","doi-asserted-by":"publisher","DOI":"10.1021\/jf403900q"},{"key":"e_1_3_2_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20973"},{"key":"e_1_3_2_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbalip.2018.08.004"},{"key":"e_1_3_2_29_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jafc.7b06146"},{"key":"e_1_3_2_30_1","doi-asserted-by":"publisher","DOI":"10.1080\/10408398.2021.1888692"},{"key":"e_1_3_2_31_1","doi-asserted-by":"publisher","DOI":"10.1042\/BJ20011777"},{"key":"e_1_3_2_32_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M204887200"},{"key":"e_1_3_2_33_1","doi-asserted-by":"publisher","DOI":"10.1007\/s003940200008"},{"key":"e_1_3_2_34_1","doi-asserted-by":"publisher","DOI":"10.1139\/cjpp-2019-0295"},{"key":"e_1_3_2_35_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/130.4.767"},{"key":"e_1_3_2_36_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature10809"},{"key":"e_1_3_2_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-6915(99)00030-7"},{"key":"e_1_3_2_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2005.01.031"},{"key":"e_1_3_2_39_1","doi-asserted-by":"publisher","DOI":"10.3177\/jnsv.35.361"},{"key":"e_1_3_2_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.201600828"},{"key":"e_1_3_2_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nutres.2009.10.016"},{"key":"e_1_3_2_42_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI76738"},{"key":"e_1_3_2_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2275(20)32378-6"},{"key":"e_1_3_2_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2275(20)38365-6"},{"key":"e_1_3_2_45_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M304153200"},{"key":"e_1_3_2_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sjbs.2020.11.045"},{"key":"e_1_3_2_47_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejcn.1602765"},{"key":"e_1_3_2_48_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0028-1091978"},{"key":"e_1_3_2_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9150(77)90180-0"},{"key":"e_1_3_2_50_1","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/6621644"},{"key":"e_1_3_2_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2011.06.004"},{"key":"e_1_3_2_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(95)00263-6"},{"key":"e_1_3_2_53_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12944-016-0194-7"},{"key":"e_1_3_2_54_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19082199"},{"key":"e_1_3_2_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nut.2012.05.002"},{"key":"e_1_3_2_56_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/35.4.697"},{"key":"e_1_3_2_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.plipres.2018.04.001"},{"key":"e_1_3_2_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5849(03)00465-9"},{"key":"e_1_3_2_59_1","doi-asserted-by":"publisher","DOI":"10.1111\/hepr.12887"},{"key":"e_1_3_2_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2012.02.026"},{"key":"e_1_3_2_61_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00250.2011"},{"key":"e_1_3_2_62_1","doi-asserted-by":"publisher","DOI":"10.1080\/07315724.2008.10719683"},{"key":"e_1_3_2_63_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-017-0806-8"},{"key":"e_1_3_2_64_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00328.2001"},{"key":"e_1_3_2_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2012.07.013"},{"key":"e_1_3_2_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rec.2014.07.035"},{"key":"e_1_3_2_67_1","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.119.256792"},{"key":"e_1_3_2_68_1","doi-asserted-by":"publisher","DOI":"10.1097\/TP.0000000000002480"},{"key":"e_1_3_2_69_1","doi-asserted-by":"publisher","DOI":"10.3945\/jn.108.103481"},{"key":"e_1_3_2_70_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0110758"},{"key":"e_1_3_2_71_1","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.M500272-JLR200"},{"key":"e_1_3_2_72_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.23229"},{"key":"e_1_3_2_73_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114514000750"},{"key":"e_1_3_2_74_1","doi-asserted-by":"publisher","DOI":"10.1186\/1476-511X-8-45"},{"key":"e_1_3_2_75_1","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.201000027"},{"key":"e_1_3_2_76_1","doi-asserted-by":"publisher","DOI":"10.3945\/jn.115.215061"},{"key":"e_1_3_2_77_1","doi-asserted-by":"publisher","DOI":"10.1186\/1476-511X-13-5"},{"key":"e_1_3_2_78_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-15684-0"},{"issue":"599959","key":"e_1_3_2_79_1","first-page":"599959","article-title":"Phytosterols: From preclinical evidence to potential clinical applications","volume":"11","author":"Salehi B.","year":"2020","unstructured":"Salehi, B., C. Quispe, J. Sharifi-Rad, N. Cruz-Martins, M. Nigam, A. P. Mishra, D. A. Konovalov, V. Orobinskaya, I. M. Abu-Reidah, W. Zam, et\u00a0al. 2020. Phytosterols: From preclinical evidence to potential clinical applications. Frontiers in Pharmacology 11 (599959):599959.","journal-title":"Frontiers in Pharmacology"},{"key":"e_1_3_2_80_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000116766.31036.03"},{"key":"e_1_3_2_81_1","doi-asserted-by":"publisher","DOI":"10.2174\/1389201020666190219122357"},{"key":"e_1_3_2_82_1","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.M052407"},{"key":"e_1_3_2_83_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.850400"},{"key":"e_1_3_2_84_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.numecd.2010.12.004"},{"key":"e_1_3_2_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2275(20)41732-8"},{"key":"e_1_3_2_86_1","doi-asserted-by":"publisher","DOI":"10.1039\/C9FO01570A"},{"key":"e_1_3_2_87_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep41604"},{"key":"e_1_3_2_88_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114520000495"},{"key":"e_1_3_2_89_1","doi-asserted-by":"publisher","DOI":"10.1089\/jmf.2019.4468"},{"key":"e_1_3_2_90_1","doi-asserted-by":"publisher","DOI":"10.3177\/jnsv.53.63"},{"key":"e_1_3_2_91_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11745-009-3367-6"},{"key":"e_1_3_2_92_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(01)02053-7"},{"key":"e_1_3_2_93_1","doi-asserted-by":"publisher","DOI":"10.1134\/S0006297916080046"},{"issue":"2","key":"e_1_3_2_94_1","first-page":"291","article-title":"The influence of phytosterols on the absorption of cholesterol","volume":"4","author":"Valkema A. J.","year":"1955","unstructured":"Valkema, A. J. 1955. The influence of phytosterols on the absorption of cholesterol. Acta physiologica et pharmacologica Neerlandica 4 (2):291\u20132.","journal-title":"Acta physiologica et pharmacologica Neerlandica"},{"key":"e_1_3_2_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2005.02.025"},{"key":"e_1_3_2_96_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114507876203"},{"key":"e_1_3_2_97_1","doi-asserted-by":"publisher","DOI":"10.5604\/01.3001.0010.5495"},{"key":"e_1_3_2_98_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI22186"}],"container-title":["Critical Reviews in Food Science and Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/10408398.2021.2006137","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/full-xml\/10.1080\/10408398.2021.2006137","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/10408398.2021.2006137","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T21:32:15Z","timestamp":1793655135000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/10408398.2021.2006137"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,6]]},"references-count":97,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2023,8,7]]}},"alternative-id":["10.1080\/10408398.2021.2006137"],"URL":"https:\/\/doi.org\/10.1080\/10408398.2021.2006137","relation":{},"ISSN":["1040-8398","1549-7852"],"issn-type":[{"value":"1040-8398","type":"print"},{"value":"1549-7852","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,6]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=bfsn20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=bfsn20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2021-12-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}