{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T10:33:11Z","timestamp":1793183591964,"version":"4.5.0"},"reference-count":157,"publisher":"Informa UK Limited","issue":"1","license":[{"start":{"date-parts":[[2020,11,10]],"date-time":"2020-11-10T00:00:00Z","timestamp":1604966400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Critical Reviews in Biochemistry and Molecular Biology"],"published-print":{"date-parts":[[2021,1,2]]},"DOI":"10.1080\/10409238.2020.1841726","type":"journal-article","created":{"date-parts":[[2020,11,11]],"date-time":"2020-11-11T02:28:08Z","timestamp":1605061688000},"page":"31-53","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":40,"title":["Repeat RNA expansion disorders of the nervous system: post-transcriptional mechanisms and therapeutic strategies"],"prefix":"10.1080","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4263-2829","authenticated-orcid":false,"given":"Joshua L.","family":"Schwartz","sequence":"first","affiliation":[{"name":"Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krysten Leigh","family":"Jones","sequence":"additional","affiliation":[{"name":"Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0799-6037","authenticated-orcid":false,"given":"Gene W.","family":"Yeo","sequence":"additional","affiliation":[{"name":"Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2020,11,10]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1038\/nature24049"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1901484116"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2014.11.058"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1007\/s13311-019-00790-9"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1021\/acs.langmuir.6b02499"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1038\/s41374-019-0241-x"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.3390\/ncrna5010011"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2014.08.027"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2017.07.010"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-020-00607-7"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1089\/scd.2017.0085"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2018.05.002"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-89689-2_4"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddw073"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.3727\/000000006781510705"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1177\/1759091419899782"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1038\/nphys3532"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20236041"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.1016\/j.dnarep.2013.04.019"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.08881"},{"issue":"4","key":"CIT0021","first-page":"1584","volume":"45","author":"Cammas A","year":"2017","journal-title":"Nucleic Acids Res"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1111\/cns.12841"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-018-0326-x"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.20703"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1111\/febs.12375"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2017.01.013"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2005.09.002"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-biophys-121219-081629"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1038\/s41593-019-0397-0"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.R118.003237"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1016\/j.gde.2014.03.002"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1126\/science.1245831"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaq0180"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1038\/s41431-018-0156-9"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1000600"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.a.38494"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2013.10.015"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.1007\/s13311-019-00777-6"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2013.04.019"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/11.7.805"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.REV119.007895"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.4161\/rna.8.6.17907"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.1038\/nchembio.577"},{"issue":"4","key":"CIT0044","first-page":"759","volume":"63","author":"Fiszer A","year":"2016","journal-title":"Acta Biochim Pol"},{"key":"CIT0045","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-biochem-061909-093311"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.1038\/srep01016"},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1038\/nature14974"},{"key":"CIT0048","doi-asserted-by":"publisher","DOI":"10.3389\/fnmol.2017.00035"},{"key":"CIT0049","doi-asserted-by":"publisher","DOI":"10.1038\/s41593-018-0221-2"},{"key":"CIT0050","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-13469-8"},{"key":"CIT0051","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1206506109"},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2017.03.027"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a024224"},{"key":"CIT0054","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2014.09.029"},{"key":"CIT0055","doi-asserted-by":"publisher","DOI":"10.4161\/rna.26706"},{"key":"CIT0056","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-02200-0"},{"key":"CIT0057","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2017.03.023"},{"key":"CIT0058","doi-asserted-by":"publisher","DOI":"10.1038\/nrn.2016.38"},{"key":"CIT0059","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-013-1138-1"},{"key":"CIT0060","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2017.65"},{"key":"CIT0061","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbagrm.2019.07.006"},{"key":"CIT0062","doi-asserted-by":"publisher","DOI":"10.1038\/nrg.2017.115"},{"key":"CIT0063","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms16063"},{"key":"CIT0064","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2016.1210368"},{"key":"CIT0065","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddy018"},{"key":"CIT0066","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2009.08.037"},{"key":"CIT0067","doi-asserted-by":"publisher","DOI":"10.1016\/j.omtm.2020.05.024"},{"key":"CIT0068","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2017.02.046"},{"key":"CIT0069","doi-asserted-by":"publisher","DOI":"10.1007\/s13311-019-00804-6"},{"key":"CIT0070","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awh650"},{"key":"CIT0071","doi-asserted-by":"publisher","DOI":"10.1038\/nature22386"},{"key":"CIT0072","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a024240"},{"key":"CIT0073","doi-asserted-by":"publisher","DOI":"10.1038\/nn.4085"},{"key":"CIT0074","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-biochem-010909-095056"},{"key":"CIT0075","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.02.033"},{"key":"CIT0076","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms4216"},{"key":"CIT0077","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2012.05.009"},{"key":"CIT0078","doi-asserted-by":"publisher","DOI":"10.1016\/j.omtn.2019.12.012"},{"key":"CIT0079","doi-asserted-by":"publisher","DOI":"10.1038\/s41588-018-0070-7"},{"key":"CIT0080","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddu378"},{"key":"CIT0081","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddw215"},{"key":"CIT0082","doi-asserted-by":"publisher","DOI":"10.1038\/352077a0"},{"key":"CIT0083","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddm293"},{"key":"CIT0084","doi-asserted-by":"publisher","DOI":"10.1126\/science.aba4624"},{"key":"CIT0085","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2013.10.049"},{"key":"CIT0086","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2017.06.002"},{"key":"CIT0087","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pathmechdis-012418-012857"},{"key":"CIT0088","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0909740107"},{"key":"CIT0089","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.01.012"},{"key":"CIT0090","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2016.09.015"},{"key":"CIT0091","doi-asserted-by":"publisher","DOI":"10.1186\/s40478-019-0796-1"},{"key":"CIT0092","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/10.19.2165"},{"key":"CIT0093","doi-asserted-by":"publisher","DOI":"10.1186\/2051-5960-1-68"},{"key":"CIT0094","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2017.12.032"},{"key":"CIT0095","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-vision-091718-014852"},{"key":"CIT0096","doi-asserted-by":"publisher","DOI":"10.3389\/fnmol.2017.00089"},{"key":"CIT0097","doi-asserted-by":"publisher","DOI":"10.1038\/ejhg.2013.32"},{"key":"CIT0098","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20215434"},{"key":"CIT0099","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2019.104635"},{"key":"CIT0100","doi-asserted-by":"publisher","DOI":"10.1038\/nrg2828"},{"key":"CIT0101","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-89689-2_8"},{"key":"CIT0102","doi-asserted-by":"publisher","DOI":"10.1038\/ng1827"},{"key":"CIT0103","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2016.02.054"},{"key":"CIT0104","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2013.02.022"},{"key":"CIT0105","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-neuro-070918-050405"},{"key":"CIT0106","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2019.03.014"},{"key":"CIT0107","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuint.2015.10.004"},{"key":"CIT0108","doi-asserted-by":"publisher","DOI":"10.1002\/jnr.21655"},{"key":"CIT0109","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.neuro.29.051605.113042"},{"key":"CIT0110","doi-asserted-by":"publisher","DOI":"10.1038\/s41582-020-0330-x"},{"key":"CIT0111","doi-asserted-by":"publisher","DOI":"10.1016\/j.bj.2019.10.005"},{"key":"CIT0112","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111.255224"},{"key":"CIT0113","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-444-63233-3.00009-9"},{"key":"CIT0114","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2010.11.012"},{"key":"CIT0115","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkv029"},{"key":"CIT0116","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2017.09.033"},{"key":"CIT0117","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcb.2010.09.013"},{"key":"CIT0118","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1901893116"},{"key":"CIT0119","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2017.148"},{"key":"CIT0120","doi-asserted-by":"publisher","DOI":"10.1038\/s41593-020-0590-1"},{"key":"CIT0121","doi-asserted-by":"publisher","DOI":"10.1186\/s40478-017-0468-y"},{"key":"CIT0122","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2014.12.063"},{"key":"CIT0123","doi-asserted-by":"publisher","DOI":"10.1002\/ana.21081"},{"key":"CIT0124","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1221891110"},{"key":"CIT0125","doi-asserted-by":"publisher","DOI":"10.1016\/j.dnarep.2015.11.008"},{"key":"CIT0126","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2013.02.004"},{"key":"CIT0127","doi-asserted-by":"publisher","DOI":"10.1038\/emboj.2010.21"},{"key":"CIT0128","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-02729-0"},{"key":"CIT0129","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1620293114"},{"key":"CIT0130","doi-asserted-by":"publisher","DOI":"10.1007\/s00438-016-1219-7"},{"key":"CIT0131","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2009.07.079"},{"key":"CIT0132","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2015.11.028"},{"key":"CIT0133","doi-asserted-by":"publisher","DOI":"10.1016\/j.omtm.2018.06.006"},{"key":"CIT0134","doi-asserted-by":"publisher","DOI":"10.1038\/s41556-019-0454-7"},{"key":"CIT0135","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gks885"},{"key":"CIT0136","doi-asserted-by":"publisher","DOI":"10.15252\/embj.2018101112"},{"key":"CIT0137","doi-asserted-by":"publisher","DOI":"10.4161\/rna.1.2.1035"},{"key":"CIT0138","doi-asserted-by":"publisher","DOI":"10.1016\/j.ncl.2014.04.011"},{"issue":"3","key":"CIT0139","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1002\/ana.21948","volume":"67","author":"Todd PK","year":"2010","journal-title":"Ann Neurol"},{"key":"CIT0140","doi-asserted-by":"publisher","DOI":"10.1016\/j.omtn.2017.06.019"},{"key":"CIT0141","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2017.00082"},{"key":"CIT0142","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymeth.2015.11.017"},{"key":"CIT0143","doi-asserted-by":"publisher","DOI":"10.1261\/rna.068940.118"},{"key":"CIT0144","doi-asserted-by":"publisher","DOI":"10.15252\/embr.201438534"},{"key":"CIT0145","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20140214"},{"key":"CIT0146","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2009.12.077"},{"key":"CIT0147","doi-asserted-by":"publisher","DOI":"10.1038\/nature11362"},{"key":"CIT0148","doi-asserted-by":"publisher","DOI":"10.1126\/science.1173110"},{"key":"CIT0149","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21093038"},{"key":"CIT0150","doi-asserted-by":"publisher","DOI":"10.1038\/s41593-019-0455-7"},{"key":"CIT0151","doi-asserted-by":"publisher","DOI":"10.1126\/science.aah6895"},{"key":"CIT0152","doi-asserted-by":"publisher","DOI":"10.1038\/gim.2012.34"},{"key":"CIT0153","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2015.09.017"},{"key":"CIT0154","doi-asserted-by":"publisher","DOI":"10.1038\/nature14973"},{"key":"CIT0155","doi-asserted-by":"publisher","DOI":"10.1016\/j.gde.2017.01.005"},{"key":"CIT0156","doi-asserted-by":"publisher","DOI":"10.1038\/nn.4272"},{"key":"CIT0157","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1013343108"}],"container-title":["Critical Reviews in Biochemistry and Molecular Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/10409238.2020.1841726","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,26]],"date-time":"2023-10-26T19:15:58Z","timestamp":1698347758000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/10409238.2020.1841726"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11,10]]},"references-count":157,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1,2]]}},"alternative-id":["10.1080\/10409238.2020.1841726"],"URL":"https:\/\/doi.org\/10.1080\/10409238.2020.1841726","relation":{},"ISSN":["1040-9238","1549-7798"],"issn-type":[{"value":"1040-9238","type":"print"},{"value":"1549-7798","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,11,10]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ibmg20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ibmg20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2020-06-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-01","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-10-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-11-10","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}