{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T17:40:33Z","timestamp":1772732433015,"version":"3.50.1"},"reference-count":58,"publisher":"Informa UK Limited","issue":"11","funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["CA016672"],"award-info":[{"award-number":["CA016672"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Stephen L. and Lavinia Boyd"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Leukemia &amp; Lymphoma"],"published-print":{"date-parts":[[2017,11,2]]},"DOI":"10.1080\/10428194.2017.1306647","type":"journal-article","created":{"date-parts":[[2017,4,10]],"date-time":"2017-04-10T09:51:21Z","timestamp":1491817881000},"page":"2705-2716","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":8,"title":["The PARP inhibitor olaparib enhances the cytotoxicity of combined gemcitabine, busulfan and melphalan in lymphoma cells"],"prefix":"10.1080","volume":"58","author":[{"given":"Benigno C.","family":"Valdez","sequence":"first","affiliation":[{"name":",","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Li","sequence":"additional","affiliation":[{"name":",","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Murray","sequence":"additional","affiliation":[{"name":",","place":["Canada"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Liu","sequence":"additional","affiliation":[{"name":",","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yago","family":"Nieto","sequence":"additional","affiliation":[{"name":",","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard E.","family":"Champlin","sequence":"additional","affiliation":[{"name":",","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Borje S.","family":"Andersson","sequence":"additional","affiliation":[{"name":",","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2017,4,10]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pop.2016.07.012"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(93)92411-L"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199512073332305"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)08938-9"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2012.10.029"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2015.06.003"},{"key":"e_1_3_2_8_1","first-page":"3","article-title":"Gemcitabine: preclinical pharmacology and mechanisms of action","volume":"23","author":"Plunkett W","year":"1996","unstructured":"Plunkett W, Huang P, Searcy CE, et\u00a0al. Gemcitabine: preclinical pharmacology and mechanisms of action. Semin Oncol. 1996;23:3\u201315.","journal-title":"Semin Oncol"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/em.20603"},{"key":"e_1_3_2_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exphem.2012.06.001"},{"key":"e_1_3_2_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.30100"},{"key":"e_1_3_2_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-12-436"},{"key":"e_1_3_2_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3342"},{"key":"e_1_3_2_14_1","doi-asserted-by":"publisher","DOI":"10.2174\/187152008784220366"},{"key":"e_1_3_2_15_1","doi-asserted-by":"publisher","DOI":"10.2741\/3297"},{"key":"e_1_3_2_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/emboj.2009.206"},{"key":"e_1_3_2_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gpb.2016.05.001"},{"key":"e_1_3_2_18_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-12-2753"},{"key":"e_1_3_2_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(16)30376-X"},{"key":"e_1_3_2_20_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1105535"},{"key":"e_1_3_2_21_1","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2015-0319"},{"key":"e_1_3_2_22_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1506859"},{"key":"e_1_3_2_23_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2014.60.0320"},{"key":"e_1_3_2_24_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-01-265769"},{"key":"e_1_3_2_25_1","doi-asserted-by":"publisher","DOI":"10.1097\/MNM.0b013e32834a369b"},{"key":"e_1_3_2_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.leukres.2009.08.014"},{"key":"e_1_3_2_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/bcj.2013.69"},{"key":"e_1_3_2_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2008.316"},{"key":"e_1_3_2_29_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.10.5858"},{"key":"e_1_3_2_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/35043058"},{"key":"e_1_3_2_31_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12915-014-0094-0"},{"key":"e_1_3_2_32_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.128272"},{"key":"e_1_3_2_33_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm805"},{"key":"e_1_3_2_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/35013083"},{"key":"e_1_3_2_35_1","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/20.22.6530"},{"key":"e_1_3_2_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(01)00195-7"},{"key":"e_1_3_2_37_1","doi-asserted-by":"publisher","DOI":"10.1128\/mcb.14.1.68-76.1994"},{"key":"e_1_3_2_38_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.18.6.3563"},{"key":"e_1_3_2_39_1","doi-asserted-by":"publisher","DOI":"10.1042\/BJ20090942"},{"key":"e_1_3_2_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80434-1"},{"key":"e_1_3_2_41_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1207205"},{"key":"e_1_3_2_42_1","doi-asserted-by":"publisher","DOI":"10.1038\/17135"},{"key":"e_1_3_2_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exphem.2013.04.009"},{"key":"e_1_3_2_44_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-61779-382-0_12"},{"key":"e_1_3_2_45_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112355200"},{"key":"e_1_3_2_46_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1203129"},{"key":"e_1_3_2_47_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.095000"},{"key":"e_1_3_2_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2012.05.011"},{"key":"e_1_3_2_49_1","first-page":"2386","article-title":"Effects of 2-chloro-9-(2-deoxy-2-fluoro-beta-d-arabinofuranosyl)adenine on K562 cellular metabolism and the inhibition of human ribonucleotide reductase and DNA polymerases by its 5\u2032-triphosphate","volume":"51","author":"Parker WB","year":"1991","unstructured":"Parker WB, Shaddix SC, Chang CH, et\u00a0al. Effects of 2-chloro-9-(2-deoxy-2-fluoro-beta-d-arabinofuranosyl)adenine on K562 cellular metabolism and the inhibition of human ribonucleotide reductase and DNA polymerases by its 5\u2032-triphosphate. Cancer Res. 1991;51:2386\u20132394.","journal-title":"Cancer Res"},{"key":"e_1_3_2_50_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj3420249"},{"key":"e_1_3_2_51_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom3010001"},{"key":"e_1_3_2_52_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M210992200"},{"key":"e_1_3_2_53_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0749.2007.00414.x"},{"key":"e_1_3_2_54_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10637-011-9682-9"},{"key":"e_1_3_2_55_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2011.8"},{"key":"e_1_3_2_56_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2014.345"},{"key":"e_1_3_2_57_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-09-1245"},{"key":"e_1_3_2_58_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-11-1227"},{"key":"e_1_3_2_59_1","doi-asserted-by":"publisher","DOI":"10.1002\/hon.1020"}],"container-title":["Leukemia &amp; Lymphoma"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/10428194.2017.1306647","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T16:44:15Z","timestamp":1772729055000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/10428194.2017.1306647"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,10]]},"references-count":58,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2017,11,2]]}},"alternative-id":["10.1080\/10428194.2017.1306647"],"URL":"https:\/\/doi.org\/10.1080\/10428194.2017.1306647","relation":{},"ISSN":["1042-8194","1029-2403"],"issn-type":[{"value":"1042-8194","type":"print"},{"value":"1029-2403","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4,10]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ilal20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ilal20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2017-01-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-03-01","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-03-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-04-10","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}