{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T06:39:15Z","timestamp":1777703955394,"version":"3.51.4"},"reference-count":34,"publisher":"Informa UK Limited","issue":"3","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Leukemia &amp; Lymphoma"],"published-print":{"date-parts":[[2020,2,23]]},"DOI":"10.1080\/10428194.2019.1689391","type":"journal-article","created":{"date-parts":[[2019,11,20]],"date-time":"2019-11-20T06:23:38Z","timestamp":1574231018000},"page":"699-706","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":6,"title":["Cereblon (<i>CRBN<\/i>) gene polymorphisms predict clinical response and progression-free survival in relapsed\/refractory multiple myeloma patients treated with lenalidomide: a pharmacogenetic study from the IMMEnSE consortium"],"prefix":"10.1080","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2772-8870","authenticated-orcid":false,"given":"El\u017cbieta","family":"Iskierka-Ja\u017cd\u017cewska","sequence":"first","affiliation":[{"name":"Department of Hematology, Copernicus Memorial Hospital, Medical University, Lodz, Poland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4261-4583","authenticated-orcid":false,"given":"Federico","family":"Canzian","sequence":"additional","affiliation":[{"name":"German Cancer Research Center (DKFZ), Heidelberg, Germany;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"St\u0119pie\u0144","sequence":"additional","affiliation":[{"name":"Laboratory of Clinical and Transplant Immunology and Genetics, Copernicus Memorial Hospital, Lodz, Poland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Martino","sequence":"additional","affiliation":[{"name":"German Cancer Research Center (DKFZ), Heidelberg, Germany;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniele","family":"Campa","sequence":"additional","affiliation":[{"name":"Department of Biology, University of Pisa, Pisa, Italy;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angelica","family":"Stein","sequence":"additional","affiliation":[{"name":"German Cancer Research Center (DKFZ), Heidelberg, Germany;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ma\u0142gorzata","family":"Krawczyk-Kuli\u015b","sequence":"additional","affiliation":[{"name":"Department of Hematology and BMT, Silesian Medical University Hospital SPSKM, Katowice, Poland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malwina","family":"Rybicka-Ramos","sequence":"additional","affiliation":[{"name":"Department of Hematology, Specialist Hospital No. 1 in Bytom, Bytom, Poland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u0142awomira","family":"Kyrcz-Krzemie\u0144","sequence":"additional","affiliation":[{"name":"Department of Hematology and BMT, Silesian Medical University Hospital SPSKM, Katowice, Poland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aleksandra","family":"Butrym","sequence":"additional","affiliation":[{"name":"Department of Cancer Prevention and Therapy, Wroclaw Medical University, Wroclaw, Poland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grzegorz","family":"Mazur","sequence":"additional","affiliation":[{"name":"Department of Cancer Prevention and Therapy, Wroclaw Medical University, Wroclaw, Poland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Artur","family":"Jurczyszyn","sequence":"additional","affiliation":[{"name":"Department and Clinic of Internal and Occupational Diseases and Hypertension, Wroclaw Medical University, Wroclaw, Poland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daria","family":"Zawirska","sequence":"additional","affiliation":[{"name":"Department and Clinic of Internal and Occupational Diseases and Hypertension, Wroclaw Medical University, Wroclaw, Poland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norbert","family":"Grz\u0105\u015bko","sequence":"additional","affiliation":[{"name":"Department of Haematology, Jagiellonian University Medical College, Cracow, Poland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Waldemar","family":"Tomczak","sequence":"additional","affiliation":[{"name":"Department of Haematooncology and Bone Marrow Transplantation, Medical University of Lublin, Lublin, Poland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edyta","family":"Subocz","sequence":"additional","affiliation":[{"name":"Department of Hematology, Military Institute of Medicine, Warsaw, Poland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marzena","family":"W\u0105tek","sequence":"additional","affiliation":[{"name":"Department of Hematology, Holycross Cancer Center, Kielce, Poland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcin","family":"Pasiarski","sequence":"additional","affiliation":[{"name":"Department of Hematology, Holycross Cancer Center, Kielce, Poland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcin","family":"Rymko","sequence":"additional","affiliation":[{"name":"Department of Hematology, Copernicus Hospital, Torun, Poland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ma\u0142gorzata","family":"Ca\u0142becka","sequence":"additional","affiliation":[{"name":"Department of Hematology, Copernicus Hospital, Torun, Poland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agnieszka","family":"Druzd-Sitek","sequence":"additional","affiliation":[{"name":"Department of Lymphoid Malignancies, Maria Sklodowska-Curie Institute Oncology Centre, Warsaw, Poland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan","family":"Walewski","sequence":"additional","affiliation":[{"name":"Department of Lymphoid Malignancies, Maria Sklodowska-Curie Institute Oncology Centre, Warsaw, Poland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcin","family":"Kruszewski","sequence":"additional","affiliation":[{"name":"Department of Hematology, University Hospital, Bydgoszcz, Poland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ma\u0142gorzata","family":"Ra\u017any","sequence":"additional","affiliation":[{"name":"Department of Haematology, Rydygier Memorial Hospital, Cracow, Poland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jan Maciej","family":"Zaucha","sequence":"additional","affiliation":[{"name":"Department of Oncological Propaedeutics, Medical University of Gdansk, Gdansk, Poland;"},{"name":"Gdynia Oncology Center, Gdynia, Poland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marek","family":"Dudzi\u0144ski","sequence":"additional","affiliation":[{"name":"Rzeszow Regional Hospital, Rzeszow, Poland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pawe\u0142","family":"Gaj","sequence":"additional","affiliation":[{"name":"Laboratory of Human Cancer Genetics, Centre of New Technologies, University of Warsaw, Warsaw, Poland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tadeusz","family":"Robak","sequence":"additional","affiliation":[{"name":"Department of Hematology, Copernicus Memorial Hospital, Medical University, Lodz, Poland;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krzysztof","family":"Warzocha","sequence":"additional","affiliation":[{"name":"Department of Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krzysztof","family":"Jamroziak","sequence":"additional","affiliation":[{"name":"Department of Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2019,11,20]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199911183412102"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa070596"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa070594"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2016.66.7295"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-07-364315"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-02-700872"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1080\/10428194.2016.1180685"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1126\/science.1177319"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-05-356063"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.55.3.335"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.3109\/10428190903350405"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2403058"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.3892\/mco.2014.307"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2012.119"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-02-557819"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1126\/science.1244851"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1126\/science.1244917"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1038\/bcj.2015.66"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-02-698092"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.12338"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1016\/j.leukres.2013.08.015"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1016\/j.clml.2016.08.007"},{"key":"CIT0023","first-page":"931","volume":"120","author":"Klimowicz A","year":"2012","journal-title":"Blood (ASH Annual Meeting Abstracts)"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-014-2063-7"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1080\/10428194.2018.1466290"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1080\/10428194.2018.1485915"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-11-611426"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.12622"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2013.315"},{"key":"CIT0030","first-page":"625","volume":"40","author":"Martino A","year":"2012","journal-title":"Int J Oncol"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1038\/sj.hdy.6800717"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.25307"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1007\/s00005-016-0442-6"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1016\/j.leukres.2015.10.007"}],"container-title":["Leukemia &amp; Lymphoma"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/10428194.2019.1689391","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,2,17]],"date-time":"2020-02-17T05:18:01Z","timestamp":1581916681000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/10428194.2019.1689391"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,20]]},"references-count":34,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,2,23]]}},"alternative-id":["10.1080\/10428194.2019.1689391"],"URL":"https:\/\/doi.org\/10.1080\/10428194.2019.1689391","relation":{},"ISSN":["1042-8194","1029-2403"],"issn-type":[{"value":"1042-8194","type":"print"},{"value":"1029-2403","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,20]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ilal20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ilal20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2019-06-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-10-16","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-10-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-11-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}