{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T19:40:22Z","timestamp":1778269222290,"version":"3.51.4"},"reference-count":37,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2010,2,18]],"date-time":"2010-02-18T00:00:00Z","timestamp":1266451200000},"content-version":"vor","delay-in-days":2239,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["American J Addict"],"published-print":{"date-parts":[[2004,1,2]]},"abstract":"<jats:p>Little is known about the frequency, severity, and risk factors for disease in drug\u2010 and alcohol\u2010dependent persons without primary medical care. Our aims are to assess the burden of medical illness, identify patient and substance dependence characteristics associated with worse physical health, and compare measures of illness burden in this population. This was accomplished through a cross\u2010sectional study among alcohol\u2010, heroin\u2010 or cocaine\u2010dependent persons without primary medical care who were admitted to an urban inpatient detoxification unit. The mean age of these patients was 35.7 (SD 7.8) years; 76% were male and 46% were Black. Forty\u2010five percent reported being diagnosed with a chronic illness, and 80% had prior medical hospitalizations. The mean age\u2010adjusted SF\u201036 Physical Component Summary (PCS) score was lower than the general U.S. population norm (44.1 vs 50.1; p &lt; 0.001). In multivariable analysis, female gender (adjusted mean change in PCS score: \u22123.71 points, p = .002), problem use of hallucinogens (\u22123.51, p = 0.013), heroin (\u22122.94, p = 0.008), other opiates (\u22123.20, p = .045), living alone (\u22123.15, p = .023), having medical insurance (\u22122.26, p = 0.014) and older age (\u2212.22 points per year, p = 0.001) were associated with worse health. From these data, it seems that alcohol\u2010 and drug\u2010dependent persons without primary medical care have a substantial burden of medical illness compared to age\u2010 and gender\u2010matched U.S. population controls. While the optimal measure of medical illness burden in this population is unclear, a variety of health measures document this medical illness burden in addicted persons.<\/jats:p>","DOI":"10.1080\/10550490490265307","type":"journal-article","created":{"date-parts":[[2004,9,29]],"date-time":"2004-09-29T20:55:56Z","timestamp":1096491356000},"page":"33-45","source":"Crossref","is-referenced-by-count":91,"title":["Burden of Medical Illness in Drug\u2010 and Alcohol\u2010dependent Persons Without Primary Care"],"prefix":"10.1111","volume":"13","author":[{"given":"Israel De","family":"Alba","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey H.","family":"Samet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Saitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2010,2,18]]},"reference":[{"key":"e_1_2_6_2_2","unstructured":"National Household Survey on Drug Abuse 1999.Substance abuse and mental health services administration. 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