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As part of five\u2010 and ten\u2010year case\u2010control longitudinal family studies of ADHD, responses to the Drug Use Screening Inventory (DUSI) were examined for evidence of self\u2010medication. DUSI data from 90 ADHD probands and 96 control probands were obtained. Thirty\u2010six percent of subjects reported self\u2010medication, 25% used to get high, and 39% had unknown motivation. No significant differences were found between ADHD and controls in motivation. ADHD symptoms did not differ between self\u2010medicators and subjects using to get high. DUSI problem scores were higher in ADHD (versus controls), those using to get high (versus self\u2010medicators), and subjects using alcohol (versus other substances). More than one\u2010third of adolescents and young adults endorsed using cigarettes and substances for self\u2010medication. Studies clarifying the role of self\u2010medication in substance use disorders are necessary.<\/jats:p>","DOI":"10.1080\/10550490601082742","type":"journal-article","created":{"date-parts":[[2007,5,24]],"date-time":"2007-05-24T17:59:50Z","timestamp":1180029590000},"page":"14-23","source":"Crossref","is-referenced-by-count":118,"title":["Do Individuals with ADHD Self\u2010Medicate with Cigarettes and Substances of Abuse? 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