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Thirty\u2010eight percent of enrolled subjects were retained for two years. Ninety\u2010one percent of urine samples had no evidence of opioid use, and patient satisfaction was high. Serum transaminases remained stable from baseline. No serious adverse events related to treatment occurred. We conclude that select opioid\u2010dependent patients exhibit moderate levels of retention in primary care office\u2010based treatment.<\/jats:p>","DOI":"10.1080\/10550490701860971","type":"journal-article","created":{"date-parts":[[2008,4,8]],"date-time":"2008-04-08T09:25:49Z","timestamp":1207646749000},"page":"116-120","source":"Crossref","is-referenced-by-count":135,"title":["Long\u2010Term Treatment with Buprenorphine\/Naloxone in Primary Care: Results at 2\u20135 Years"],"prefix":"10.1111","volume":"17","author":[{"given":"David A.","family":"Fiellin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brent A.","family":"Moore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lynn E.","family":"Sullivan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William 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