{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T07:29:47Z","timestamp":1782890987431,"version":"3.54.5"},"reference-count":45,"publisher":"Informa UK Limited","issue":"7","funder":[{"name":"Clinical Key Program of Fujian Medical University","award":["XK201107"],"award-info":[{"award-number":["XK201107"]}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Clinical and Experimental Hypertension"],"published-print":{"date-parts":[[2017,10,3]]},"DOI":"10.1080\/10641963.2017.1306537","type":"journal-article","created":{"date-parts":[[2017,6,14]],"date-time":"2017-06-14T14:22:31Z","timestamp":1497450151000},"page":"612-618","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":9,"title":["Combined treatment of irbesartan and diltiazem ameliorates endothelium dependent vasodilatation in hypertensives"],"prefix":"10.1080","volume":"39","author":[{"given":"Tingting","family":"Zhou","sequence":"first","affiliation":[{"name":"Fujian Medical University, Fujian Hypertension Research Institute","place":["Fuzhou, P.R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaodong","family":"Huang","sequence":"additional","affiliation":[{"name":"Fujian Hypertension Research Institute, First Affiliated Hospital of Fujian Medical University","place":["Fuzhou, PR China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoqi","family":"Cai","sequence":"additional","affiliation":[{"name":"Fujian Hypertension Research Institute, First Affiliated Hospital of Fujian Medical University","place":["Fuzhou, PR China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liangdi","family":"Xie","sequence":"additional","affiliation":[{"name":"Fujian Hypertension Research Institute, First Affiliated Hospital of Fujian Medical University","place":["Fuzhou, PR China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2017,6,14]]},"reference":[{"issue":"3","key":"e_1_3_4_2_1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2014\/598271","article-title":"Endothelial dysfunction in experimental models of arterial hypertension: Cause or consequence?","volume":"13","author":"Bernatova I.","year":"2014","unstructured":"Bernatova I. Endothelial dysfunction in experimental models of arterial hypertension: Cause or consequence? Biomed Res Int 2014;13(3):1\u201314.","journal-title":"Biomed Res Int"},{"key":"e_1_3_4_3_1","first-page":"2315","article-title":"European guidelines on cardiovascular disease prevention in clinical practice","volume":"37","author":"Royo-Bordonada M\u00c1","year":"2016","unstructured":"Royo-Bordonada M\u00c1, Armario P, Lobos Bejarano JM, et al. European guidelines on cardiovascular disease prevention in clinical practice. Eur Heart J 2016;37:2315\u201381.","journal-title":"Eur Heart J"},{"issue":"1","key":"e_1_3_4_4_1","first-page":"61","article-title":"Vascular endothelial function in salt sensitive and non-salt sensitive subjects","volume":"39","author":"Mu JJ","year":"2011","unstructured":"Mu JJ, Zhang T, Fang Y, et al. Vascular endothelial function in salt sensitive and non-salt sensitive subjects. Zhonghua Xin Xue Guan Bing Za Zhi 2011;39(1):61\u201364.","journal-title":"Zhonghua Xin Xue Guan Bing Za Zhi"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.2147\/VHRM.S16852"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/eht151"},{"issue":"8","key":"e_1_3_4_7_1","first-page":"701","article-title":"Liu LS, on behalf of writing group of 2010 Chinese guidelines for the management of hypertension. Chinese guideline for the management of hypertension","volume":"19","year":"2011","unstructured":"Liu LS, on behalf of writing group of 2010 Chinese guidelines for the management of hypertension. Chinese guideline for the management of hypertension. Chin J Hypertens 2011;19(8):701\u201342.","journal-title":"Chin J Hypertens"},{"issue":"231","key":"e_1_3_4_8_1","first-page":"26","article-title":"State of integral remodeling parameters of target organs in patients with essential hypertension and obesity","author":"Kochueva M","year":"2014","unstructured":"Kochueva M, Sukhonos V, Shalimova A, et al. State of integral remodeling parameters of target organs in patients with essential hypertension and obesity. Georgian Med News 2014;(231):26\u201330.","journal-title":"Georgian Med News"},{"issue":"1","key":"e_1_3_4_9_1","first-page":"27","article-title":"Irbesartan administration therapeutically influences circulating endothelial progenitor cell and microparticl emobilization by involvement of pro-inflammatory cytokines","volume":"711","author":"Georgescu A","year":"2013","unstructured":"Georgescu A, Alexandru N, Nemeczb M, et al. Irbesartan administration therapeutically influences circulating endothelial progenitor cell and microparticl emobilization by involvement of pro-inflammatory cytokines. Cardiovasc Pharmacol 2013;711(1\u20133):27\u201335.","journal-title":"Cardiovasc Pharmacol"},{"key":"e_1_3_4_10_1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-08-0188"},{"key":"e_1_3_4_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajh\/hpt138"},{"key":"e_1_3_4_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(88)90467-6"},{"issue":"8","key":"e_1_3_4_13_1","first-page":"736","article-title":"Relation between serum uric acid and hypertensive LVH","volume":"21","author":"Lin LJ","year":"2013","unstructured":"Lin LJ, Xie LD. Relation between serum uric acid and hypertensive LVH. Chin J Hypertens 2013;21(8):736\u201340.","journal-title":"Chin J Hypertens"},{"key":"e_1_3_4_14_1","doi-asserted-by":"publisher","DOI":"10.4172\/2155-9880.1000416"},{"key":"e_1_3_4_15_1","first-page":"442","article-title":"Relationship between endothelium - dependent vasodilatation and uric acid in essential hypertension patients with left ventricular hypertrophy","volume":"20","author":"Shen YH, Zhang LY, Huang LJ, et al.","year":"2012","unstructured":"Shen YH, Zhang LY, Huang LJ, et al. Relationship between endothelium - dependent vasodilatation and uric acid in essential hypertension patients with left ventricular hypertrophy. Chin J Hypertens 2012;20:442\u201346.","journal-title":"Chin J Hypertens"},{"issue":"6","key":"e_1_3_4_16_1","first-page":"534","article-title":"Effects of diltiazem and fluvastatin on endothelium dependent vasodilatation in mild to moderate essential hypertensives","volume":"18","author":"Liu XH","year":"2010","unstructured":"Liu XH, Chen CL, Huang LJ, Xie LD. Effects of diltiazem and fluvastatin on endothelium dependent vasodilatation in mild to moderate essential hypertensives. Chin J Hypertens 2010;18(6):534\u201338.","journal-title":"Chin J Hypertens"},{"issue":"9","key":"e_1_3_4_17_1","first-page":"830","article-title":"The relationship between vascular overload index and intima media thickness of carotid artery in hypertensive patients","volume":"22","author":"Cai XQ, Zhang LY, Huang XD, et al.","year":"2014","unstructured":"Cai XQ, Zhang LY, Huang XD, et al. The relationship between vascular overload index and intima media thickness of carotid artery in hypertensive patients. Chin J Hypertens 2014;22(9):830\u201335.","journal-title":"Chin J Hypertens"},{"issue":"4","key":"e_1_3_4_18_1","first-page":"365","article-title":"Vasodilatation of anterior artery in essential hypertensive patients with left ventricular hypertrophy","volume":"22","author":"Zhang LY, Chen CL, Huang LJ, et al.","year":"2014","unstructured":"Zhang LY, Chen CL, Huang LJ, et al. Vasodilatation of anterior artery in essential hypertensive patients with left ventricular hypertrophy. Chin J Hypertens 2014;22(4):365\u201370.","journal-title":"Chin J Hypertens"},{"key":"e_1_3_4_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(86)90771-X"},{"issue":"18","key":"e_1_3_4_20_1","first-page":"911","article-title":"Ultrasonic branch of Chinese association for medical association. Guideline for Vascular ultrasound","volume":"10","year":"2009","unstructured":"Ultrasonic branch of Chinese association for medical association. Guideline for Vascular ultrasound. Chin J Ultrasonogr 2009;10(18):911\u201320.","journal-title":"Chin J Ultrasonogr"},{"issue":"18","key":"e_1_3_4_21_1","first-page":"817","article-title":"Endothelial dysfunction has great impacts on the development acute coronary syndrome and fatal cardiovascular events","author":"Tatsuaki M","year":"2008","unstructured":"Tatsuaki M, Ikuo M. Endothelial dysfunction has great impacts on the development acute coronary syndrome and fatal cardiovascular events. Circulation 2008;(18):817.","journal-title":"Circulation"},{"key":"e_1_3_4_22_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00179.2014"},{"key":"e_1_3_4_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.suc.2014.09.007"},{"key":"e_1_3_4_24_1","doi-asserted-by":"publisher","DOI":"10.5551\/jat.18267"},{"key":"e_1_3_4_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glu180"},{"key":"e_1_3_4_26_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00775.2014"},{"key":"e_1_3_4_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e32836522c3"},{"key":"e_1_3_4_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.27384"},{"key":"e_1_3_4_29_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0090217"},{"issue":"6","key":"e_1_3_4_30_1","first-page":"662","article-title":"Effects of valsartan on the structure and function of vessels in spontaneously hypertensive rats","volume":"8","author":"Wang HJ","year":"2003","unstructured":"Wang HJ, Xie LD, Yao EH, et al. Effects of valsartan on the structure and function of vessels in spontaneously hypertensive rats. Chin J Clin Pharmacol Ther 2003;8(6):662\u201365.","journal-title":"Chin J Clin Pharmacol Ther"},{"key":"e_1_3_4_31_1","doi-asserted-by":"publisher","DOI":"10.2174\/1381612811319130006"},{"key":"e_1_3_4_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2009.09.422"},{"key":"e_1_3_4_33_1","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2013.1263"},{"issue":"1","key":"e_1_3_4_34_1","first-page":"8","article-title":"Effects of valsartan combined with amlodipine or hydrochlorothiazide regimen on blood pressure variation in elderly hypertensive patients","volume":"40","author":"Wu ZB","year":"2012","unstructured":"Wu ZB, Zhang Y, Yu QG, et al. Effects of valsartan combined with amlodipine or hydrochlorothiazide regimen on blood pressure variation in elderly hypertensive patients. Zhonghua Xin Xue Guan Bing Za Zhi 2012;40(1):8\u201313.","journal-title":"Zhonghua Xin Xue Guan Bing Za Zhi"},{"issue":"225","key":"e_1_3_4_35_1","first-page":"72","article-title":"Dynamics the level of visfatin and markers of immune inflammation in hypertensive patients with abdominal obesity using the combination of antihypertensive therapy","author":"Andreeva AA","year":"2013","unstructured":"Andreeva AA. Dynamics the level of visfatin and markers of immune inflammation in hypertensive patients with abdominal obesity using the combination of antihypertensive therapy. Georgian Med News 2013;(225):72\u201377.","journal-title":"Georgian Med News"},{"key":"e_1_3_4_36_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.114.003039"},{"key":"e_1_3_4_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchf.2014.03.016"},{"key":"e_1_3_4_38_1","doi-asserted-by":"publisher","DOI":"10.3892\/br.2013.165"},{"key":"e_1_3_4_39_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehu467"},{"key":"e_1_3_4_40_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.113.03140"},{"key":"e_1_3_4_41_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0113460"},{"key":"e_1_3_4_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-6363(98)00079-0"},{"key":"e_1_3_4_43_1","doi-asserted-by":"publisher","DOI":"10.5603\/KP.2013.0072"},{"key":"e_1_3_4_44_1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-12-0153"},{"key":"e_1_3_4_45_1","doi-asserted-by":"publisher","DOI":"10.3109\/10641963.2012.702833"},{"key":"e_1_3_4_46_1","doi-asserted-by":"publisher","DOI":"10.3109\/10641963.2011.577491"}],"container-title":["Clinical and Experimental Hypertension"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/10641963.2017.1306537","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,2]],"date-time":"2025-05-02T13:08:19Z","timestamp":1746191299000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/10641963.2017.1306537"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,14]]},"references-count":45,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2017,10,3]]}},"alternative-id":["10.1080\/10641963.2017.1306537"],"URL":"https:\/\/doi.org\/10.1080\/10641963.2017.1306537","relation":{},"ISSN":["1064-1963","1525-6006"],"issn-type":[{"value":"1064-1963","type":"print"},{"value":"1525-6006","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6,14]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iceh20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iceh20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2016-09-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-02-20","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-03-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-06-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}