{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T07:17:52Z","timestamp":1790061472213,"version":"4.0.1"},"reference-count":46,"publisher":"Informa UK Limited","issue":"1","license":[{"start":{"date-parts":[[2023,3,23]],"date-time":"2023-03-23T00:00:00Z","timestamp":1679529600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Mechanisms of the Protective Effects of Tilianin Against Myocardium Ischemia\/Reperfusion Injury Through Ox-CaMKII-mediated Mitochondrial Regulating Pathway","award":["81760045"],"award-info":[{"award-number":["81760045"]}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Clinical and Experimental Hypertension"],"published-print":{"date-parts":[[2023,12,31]]},"DOI":"10.1080\/10641963.2023.2192444","type":"journal-article","created":{"date-parts":[[2023,3,23]],"date-time":"2023-03-23T09:00:13Z","timestamp":1679562013000},"update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":47,"title":["Hirsutine ameliorates myocardial ischemia-reperfusion injury through improving mitochondrial function via CaMKII pathway"],"prefix":"10.1080","volume":"45","author":[{"given":"Wen","family":"Jiang","sequence":"first","affiliation":[{"name":"Department of Pharmacy, The Sixth Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxiang","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Laboratory, The Sixth Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaomei","family":"Pan","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, The Sixth Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jieyu","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, The Sixth Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, The Sixth Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junhui","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, The Sixth Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2023,3,23]]},"reference":[{"key":"e_1_3_5_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12964-021-00786-z"},{"key":"e_1_3_5_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11010-020-03842-3"},{"key":"e_1_3_5_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12265-019-09886-1"},{"key":"e_1_3_5_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-03105-2"},{"key":"e_1_3_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)62001-8"},{"key":"e_1_3_5_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra071667"},{"key":"e_1_3_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2015.09.023"},{"key":"e_1_3_5_9_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00028.2018"},{"key":"e_1_3_5_10_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2014030288"},{"key":"e_1_3_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2016.03.015"},{"key":"e_1_3_5_12_1","doi-asserted-by":"publisher","DOI":"10.1042\/CS20180510"},{"key":"e_1_3_5_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.13330"},{"issue":"2","key":"e_1_3_5_14_1","first-page":"97","article-title":"Pharmacological actions of Uncaria alkaloids, rhynchophylline and isorhynchophylline","volume":"24","author":"Shi J-S","year":"2003","unstructured":"Shi J-S, J-X Y, Chen X-P, R-X X. Pharmacological actions of Uncaria alkaloids, rhynchophylline and isorhynchophylline. Acta Pharmacol Sin. 2003;24(2):97\u2013101.","journal-title":"Acta Pharmacol Sin"},{"key":"e_1_3_5_15_1","doi-asserted-by":"publisher","DOI":"10.1211\/0022357991772853"},{"key":"e_1_3_5_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2010.09.057"},{"key":"e_1_3_5_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13046-019-1201-4"},{"key":"e_1_3_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2022.102288"},{"key":"e_1_3_5_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2012.07.010"},{"key":"e_1_3_5_20_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom10081167"},{"key":"e_1_3_5_21_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/4235405"},{"key":"e_1_3_5_22_1","doi-asserted-by":"publisher","DOI":"10.3390\/life11111123"},{"key":"e_1_3_5_23_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2019.00381"},{"key":"e_1_3_5_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2021.174603"},{"key":"e_1_3_5_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2006.07.007"},{"key":"e_1_3_5_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.21138"},{"key":"e_1_3_5_27_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-022-01553-1"},{"key":"e_1_3_5_28_1","doi-asserted-by":"publisher","DOI":"10.5935\/abc.20180008"},{"key":"e_1_3_5_29_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI62874"},{"key":"e_1_3_5_30_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0119477"},{"key":"e_1_3_5_31_1","doi-asserted-by":"publisher","DOI":"10.1093\/jpp\/rgab151"},{"key":"e_1_3_5_32_1","doi-asserted-by":"publisher","DOI":"10.1177\/10742484211031327"},{"key":"e_1_3_5_33_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2020.607813"},{"key":"e_1_3_5_34_1","doi-asserted-by":"publisher","DOI":"10.4061\/2011\/693761"},{"key":"e_1_3_5_35_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2017.00296"},{"key":"e_1_3_5_36_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12866-020-1711-4"},{"key":"e_1_3_5_37_1","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/3137329"},{"key":"e_1_3_5_38_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2016.00362"},{"key":"e_1_3_5_39_1","doi-asserted-by":"publisher","DOI":"10.1021\/cb500856c"},{"key":"e_1_3_5_40_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.01138.2006"},{"key":"e_1_3_5_41_1","doi-asserted-by":"publisher","DOI":"10.1021\/tx9003193"},{"key":"e_1_3_5_42_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10495-013-0835-5"},{"key":"e_1_3_5_43_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/9421019"},{"key":"e_1_3_5_44_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-006-8014-y"},{"key":"e_1_3_5_45_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.279.5348.227"},{"key":"e_1_3_5_46_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000069686.31472.C5"},{"key":"e_1_3_5_47_1","doi-asserted-by":"publisher","DOI":"10.3892\/ijmm.2020.4823"}],"container-title":["Clinical and Experimental Hypertension"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/10641963.2023.2192444","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,29]],"date-time":"2023-11-29T11:24:09Z","timestamp":1701257049000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/10641963.2023.2192444"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3,23]]},"references-count":46,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,12,31]]}},"alternative-id":["10.1080\/10641963.2023.2192444"],"URL":"https:\/\/doi.org\/10.1080\/10641963.2023.2192444","relation":{},"ISSN":["1064-1963","1525-6006"],"issn-type":[{"value":"1064-1963","type":"print"},{"value":"1525-6006","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,3,23]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iceh20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iceh20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2023-01-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-03-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-03-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2192444"}}