{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T07:29:34Z","timestamp":1778743774089,"version":"3.51.4"},"reference-count":0,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Infectious Diseases in Obstetrics and Gynecology"],"published-print":{"date-parts":[[2003,1]]},"abstract":"<jats:p><jats:italic>Objective:<\/jats:italic> Isolation of <jats:italic>Trichosporon<\/jats:italic> species from vaginal secretions is a rare event, and no data are available on\nits pathogenic role. A case series is presented to determine the pathogenic role of <jats:italic>Trichosporon<\/jats:italic> species in\nvulvovaginal infections.<\/jats:p><jats:p><jats:italic>Methods:<\/jats:italic> We performed a retrospective chart review of patients seen in the W.S.U. Vaginitis Clinic in order\nto identify patients from whom <jats:italic>Trichosporon<\/jats:italic>  species were isolated.<\/jats:p><jats:p><jats:italic>Results:<\/jats:italic> Between 1986 and 2001, a total of 13 patients had a total of 18 positive vaginal cultures for <jats:italic>Trichosporon<\/jats:italic> species. All 18 vaginal isolates were <jats:italic>T. inkin<\/jats:italic>. In general, positive vaginal cultures were accompanied by low\nyeast colony counts. Four out of 18 positive <jats:italic>T. inkin<\/jats:italic> cultures were obtained from visits by asymptomatic patients.\nOf the remaining 14 positive <jats:italic>T. inkin<\/jats:italic> cultures from patients with symptoms, nine out of 14 cultures had other\ndiagnoses (<jats:italic>Candida albicans<\/jats:italic>, six cases; bacterial vaginosis, two cases; <jats:italic>Trichomonas<\/jats:italic>, one case). Five positive <jats:italic>T. inkin<\/jats:italic>\ncultures were obtained from visits at which patients had symptoms and no associated diagnosis. In only one of the\nfive episodes could we establish a clear pathogenic role for <jats:italic>Trichosporon<\/jats:italic>. In this case the patient was treated with\nboric acid and had resolution of symptoms and a negative culture at follow\u2010up. <jats:italic>In-vitro<\/jats:italic> susceptibility tests revealed\nthat <jats:italic>T. inkin<\/jats:italic> was resistant to flucytosine and susceptible to all topical and oral azoles.<\/jats:p><jats:p><jats:italic>Conclusions:<\/jats:italic><jats:italic>T. inkin<\/jats:italic> is occasionally found in vulvovaginal cultures and is usually a non\u2010pathogen. Transient\ncolonization tended to occur in women, usually of African\u2014American origin, with major perturbations in vaginal\nflora (bacterial vaginosis and trichomoniasis) and increased pH. Pathogenic consequences of <jats:italic>Trichosporon<\/jats:italic> colonization\nappear to be rare.<\/jats:p>","DOI":"10.1080\/10647440300025510","type":"journal-article","created":{"date-parts":[[2005,9,7]],"date-time":"2005-09-07T05:29:38Z","timestamp":1126070978000},"page":"131-133","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Vulvovaginal Trichosporonosis"],"prefix":"10.1155","volume":"11","author":[{"given":"Paul","family":"Makela","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Debbie","family":"Leaman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jack D.","family":"Sobel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2003,3,17]]},"container-title":["Infectious Diseases in Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/idog\/2003\/683908.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1080\/10647440300025510","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T21:13:43Z","timestamp":1723065223000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1080\/10647440300025510"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,1]]},"references-count":0,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2003,1]]}},"alternative-id":["10.1080\/10647440300025510"],"URL":"https:\/\/doi.org\/10.1080\/10647440300025510","archive":["Portico"],"relation":{},"ISSN":["1064-7449"],"issn-type":[{"value":"1064-7449","type":"print"}],"subject":[],"published":{"date-parts":[[2003,1]]},"assertion":[{"value":"2002-09-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2003-03-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2003-03-17","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}