{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T16:25:00Z","timestamp":1788625500809,"version":"build-2803163510"},"reference-count":0,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2000,1,1]],"date-time":"2000-01-01T00:00:00Z","timestamp":946684800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Infectious Diseases in Obstetrics and Gynecology"],"published-print":{"date-parts":[[2004,1]]},"abstract":"<jats:p><jats:italic>Objective:<\/jats:italic> To compare the Affirm VPIII Microbial Identification Test for detection and identification of <jats:italic>Candida<\/jats:italic>\nspecies, <jats:italic>Gardnerella vaginalis<\/jats:italic>  and <jats:italic>Trichomonas vaginalis<\/jats:italic>  to clinical and microscopic criteria commonly used to\ndiagnose vaginitis.<\/jats:p><jats:p><jats:italic>Methods:<\/jats:italic> Women that were symptomatic for vaginitis\/vaginosis and asymptomatic women being seen for\nroutine obstetric or gynecological care were included in this study. Women treated with antibiotics or\nantifungals within one week or women who had douched within 24 hours were excluded. Two vaginal swab\nspecimens were simultaneously obtained from each patient, one swab was placed in sterile physiological saline\nfor immediate microscopic wet mount examination and KOH testing. The other swab was placed in the Affirm\ncollection tube for Affirm VPIII testing based on previously demonstrated methods.<\/jats:p><jats:p><jats:italic>Results:<\/jats:italic> The Affirm assay was significantly more likely to identify <jats:italic>Gardnerella<\/jats:italic> and <jats:italic>Candida<\/jats:italic>  than wet mount.\n190 (45%) were positive for <jats:italic>Gardnerella<\/jats:italic> by Affirm compared to 58 (14%) by wet mount; 45 (11%) were\npositive for <jats:italic>Candida<\/jats:italic> by Affirm compared to 31 (7%) by wet mount; and 30 (7%) were positive for\n<jats:italic>Trichomonas<\/jats:italic> by Affirm compared to 23 (5%) by wet mount. Symptomatic women were significantly more\nlikely to be positive by Affirm only (23% vs. 10%), wet mount only (3% vs. 2%) or Affirm and wet mount\n(15% vs. 1%). Asymptomatic women were significantly more likely to be negative for Affirm and wet mount\n(43% vs. 5%).<\/jats:p><jats:p><jats:italic>Conclusions:<\/jats:italic>  The Affirm VPIII test is a more sensitive diagnostic test for detection and identification of\nsymptomatic vaginitis\/vaginosis than conventional clinical examination and wet mount testing.<\/jats:p>","DOI":"10.1080\/1064744042000210375","type":"journal-article","created":{"date-parts":[[2004,6,10]],"date-time":"2004-06-10T16:08:12Z","timestamp":1086883692000},"page":"17-21","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":89,"title":["Clinical Evaluation of Af\ufb01rm VPIII in the Detection andIdenti\ufb01cation of <i>Trichomonas vaginalis<\/i>, <i>Gardnerella vaginalis<\/i>, and <i>Candida<\/i> Species in Vaginitis\/Vaginosis"],"prefix":"10.1155","volume":"12","author":[{"given":"Haywood L.","family":"Brown","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deanna D.","family":"Fuller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lori T.","family":"Jasper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas E.","family":"Davis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin D.","family":"Wright","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2003,9,29]]},"container-title":["Infectious Diseases in Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/idog\/2004\/934876.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1080\/1064744042000210375","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T19:54:32Z","timestamp":1723060472000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1080\/1064744042000210375"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,9,29]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2004,1]]}},"alternative-id":["10.1080\/1064744042000210375"],"URL":"https:\/\/doi.org\/10.1080\/1064744042000210375","archive":["Portico"],"relation":{},"ISSN":["1064-7449"],"issn-type":[{"value":"1064-7449","type":"print"}],"subject":[],"published":{"date-parts":[[2003,9,29]]},"assertion":[{"value":"2003-03-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2003-09-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2003-09-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}