{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T05:41:58Z","timestamp":1790919718876,"version":"4.1.0"},"reference-count":47,"publisher":"Informa UK Limited","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Free Radical Research"],"published-print":{"date-parts":[[2005,8]]},"DOI":"10.1080\/10715760500145069","type":"journal-article","created":{"date-parts":[[2005,9,7]],"date-time":"2005-09-07T03:47:14Z","timestamp":1126064834000},"page":"865-874","source":"Crossref","is-referenced-by-count":37,"title":["Effect of arachidonic, eicosapentaenoic and docosahexaenoic acids on the oxidative status of C6 glioma cells"],"prefix":"10.1080","volume":"39","author":[{"given":"Fabiana","family":"Leonardi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucilla","family":"Attorri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita Di","family":"Benedetto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonella Di","family":"Biase","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Sanchez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirella","family":"Nardini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serafina","family":"Salvati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2009,7,7]]},"reference":[{"key":"CIT0001","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/0361-9230(93)90180-J","volume":"32","author":"Relton JK","year":"1993","journal-title":"Brain Res Bull"},{"key":"CIT0002","first-page":"307","volume":"60","author":"Leaf A","year":"1999","journal-title":"Voskuyl RA. Functional and electrophysiologic effects of polyunsaturated fatty acids on excitable tissues: Heart and brain. Prosta-glandins Leukot Essent Fatty Acids"},{"key":"CIT0003","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.1093\/emboj\/19.8.1784","volume":"19","author":"Lauritzen I","year":"2000","journal-title":"EMBO J"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4522(01)00473-0"},{"key":"CIT0005","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.plefa.2003.08.020","volume":"69","author":"Peet M","year":"2003","journal-title":"Prostaglandins Leukot Essent Fatty Acids"},{"key":"CIT0006","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/S0095-5108(18)31110-2","volume":"7","author":"Mead PB","year":"1980","journal-title":"Chin Perinatol"},{"key":"CIT0007","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1006\/abio.1996.9990","volume":"1","author":"Liu Y","year":"1997","journal-title":"Anal Biochem"},{"key":"CIT0008","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1126\/science.7901908","volume":"262","author":"Coyle JT","year":"1993","journal-title":"Science"},{"key":"CIT0009","first-page":"28294","volume":"278","author":"Marques C","year":"2003","journal-title":"Eckert A. Neurotoxic mechanisms caused by the Alzheimer's disease-linked Swedish amyloid precursor protein mutation: Oxidative stress, caspase and the JNK pathway. J Biol Chem"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-4159.1998.71052112.x"},{"key":"CIT0012","first-page":"261","volume":"251","author":"Gilgun-Sherki Y","year":"2004","journal-title":"DJ. The role of oxidative stress in the pathogenesis of multiple sclerosis: The need for effective antioxidant therapy. J Neurol"},{"key":"CIT0013","first-page":"342","volume":"43","author":"Bourre JM","year":"1984","journal-title":"Alterations in the fatty acid composition of rat brain cells (neurons, astrocytes, and oligodendrocytes) and of subcellular fractions (myelin and synaptosomes) induced by a diet devoid of n - 3 fatty acids. J Neurochem"},{"key":"CIT0014","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/0955-2863(93)90080-G","volume":"4","author":"Salvati S","year":"1993","journal-title":"J Nutr Biochem"},{"key":"CIT0015","first-page":"1596","volume":"74","author":"Brand A","year":"2000","journal-title":"N-methyl bases of ethanolamine prevent apoptotic cell death induced by oxidative stress in cells of oligodendroglia origin. J Neurochem"},{"key":"CIT0016","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1002\/glia.10246","volume":"43","author":"Ramos KL","year":"2003","journal-title":"Glia"},{"key":"CIT0017","first-page":"G338\u2013G348","volume":"282","author":"Takahashi M","year":"2002","journal-title":"Fish oil feeding alters liver gene expressions to defend against PPAR-alpha activation and ROS production. Am J Physiol Gastrointest Liver Physiol"},{"key":"CIT0018","first-page":"188","volume":"20","author":"Frost GH","year":"1989","journal-title":"Glial progenitor growth factor assay using rat glioma cells. Trans Am Soc Neurochem"},{"key":"CIT0019","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1002\/jnr.490410310","volume":"41","author":"Coyle DE","year":"1995","journal-title":"J Neurosci Res"},{"key":"CIT0020","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/0020-711X(89)90295-4","volume":"21","author":"de Almeida AF","year":"1989","journal-title":"Int J Biochem"},{"key":"CIT0021","first-page":"313","volume":"216","author":"Ghibelli L","year":"1995","journal-title":"Non oxidative loss of glutatione in apoptosis via GSH extrusion. Biochem Biophys Res Commun"},{"key":"CIT0022","doi-asserted-by":"crossref","first-page":"1910","DOI":"10.4049\/jimmunol.130.4.1910","volume":"130","author":"Bass DA","year":"1983","journal-title":"J Immunol"},{"key":"CIT0023","first-page":"257","volume":"174","author":"Bernheim F","year":"1948","journal-title":"The reaction between thiobarbituric acid and the oxidant products of certain lipids. J Biol Chem"},{"key":"CIT0024","first-page":"229","volume":"89","author":"Tarpey MM","year":"2001","journal-title":"Nitric oxide, superoxide, hydrogen peroxide, and peroxynitrite. Circ Res"},{"key":"CIT0025","first-page":"236","volume":"179","author":"Neuschwander-Tetri BA","year":"1989","journal-title":"Glutathione measurement by high performance liquid chromatography separation and fluorimetric detection of glutathione- orthophthaldehyde adduct. Anal Biochem"},{"key":"CIT0026","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0076-6879(84)05016-3","volume":"105","author":"Aebi H","year":"1984","journal-title":"Methods Enz"},{"key":"CIT0027","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1073\/pnas.82.5.1465","volume":"82","author":"Battistuzzi G","year":"1985","journal-title":"Proc Natl Acad Sci USA"},{"key":"CIT0028","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","volume":"72","author":"Bradford MM","year":"1976","journal-title":"Anal Biochem"},{"key":"CIT0029","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1042\/bj2490351","volume":"249","author":"Garg ML","year":"1988","journal-title":"Biochem J"},{"key":"CIT0030","first-page":"169","volume":"31","author":"Froyland L","year":"1996","journal-title":"Chronic administration of eicosapentaenoic acid and docosahexaenoic acid as ethyl esters reduced plasma chole-sterol and changed the fatty acid composition in rat blood and organs. Lipids"},{"key":"CIT0032","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1007\/s11745-997-0139-4","volume":"32","author":"Calviello G","year":"1997","journal-title":"Lipids"},{"key":"CIT0033","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1194\/jlr.M200120-JLR200","volume":"43","author":"Innis SM","year":"2002","journal-title":"J Lipid Res"},{"key":"CIT0034","first-page":"1481","volume":"41","author":"Udilova N","year":"2003","journal-title":"Induction of lipid peroxidation in biomem-branes by dietary oil components. Food Chem Toxicol"},{"key":"CIT0036","first-page":"793","volume":"378","author":"Cooper AJ","year":"1997","journal-title":"Biol Chem"},{"key":"CIT0037","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1046\/j.1365-2362.1999.00447.x","volume":"29","author":"Hall AG","year":"1999","journal-title":"Eur J Chin Investig"},{"key":"CIT0038","doi-asserted-by":"crossref","first-page":"1965","DOI":"10.1046\/j.1471-4159.1995.64051965.x","volume":"64","author":"Bolanos JP","year":"1995","journal-title":"J Neurochem"},{"key":"CIT0039","first-page":"895","volume":"30","author":"Delton-Vandenbroucke I","year":"2001","journal-title":"Dual regulation of glutathione peroxidase by docosahexaenoic acid in endothelial cells depending on concentration and vascular bed origin. Free Radic Biol Med"},{"key":"CIT0040","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0009-8981(03)00086-X","volume":"331","author":"Walranda S","year":"2003","journal-title":"Clin Chim Acta"},{"key":"CIT0041","doi-asserted-by":"crossref","first-page":"91S","DOI":"10.1042\/bst019091s","volume":"19","author":"Finnen M","year":"1991","journal-title":"Biochem Soc Trans"},{"key":"CIT0043","first-page":"84","volume":"76","author":"Wakatsuki A","year":"1999","journal-title":"Relation to arachidonic acid peroxidation. Biol Neonate"},{"key":"CIT0044","first-page":"3581","volume":"80","author":"Corey EJ","year":"1983","journal-title":"Docosahexaenoic acid is a strong inhibitor of prostaglandin but not leukotriene bio-synthesis. Proc Natl Acad Sci USA"},{"key":"CIT0046","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1146\/annurev.bi.52.070183.003431","volume":"52","author":"Meister A","year":"1983","journal-title":"Annu Rev Biochem"},{"key":"CIT0047","first-page":"660","volume":"262","author":"Kirkman HN","year":"1987","journal-title":"The function of catalase-bound NADPH. J Biol Chem"},{"key":"CIT0048","doi-asserted-by":"crossref","first-page":"2750","DOI":"10.1074\/jbc.274.5.2750","volume":"274","author":"Salvemini F","year":"1999","journal-title":"J Biol Chem"},{"key":"CIT0049","doi-asserted-by":"crossref","first-page":"20804","DOI":"10.1074\/jbc.M202387200","volume":"277","author":"Lonergan PE","year":"2002","journal-title":"J Biol Chem"},{"key":"CIT0050","first-page":"2457","volume":"14","author":"Wang X","year":"2003","journal-title":"Neuroprotec-tive effect of docosahexaenoic acid on glutamate-induced cytotoxicity in rat hippocampal cultures. NeuroReport"},{"key":"CIT0051","doi-asserted-by":"crossref","first-page":"2252","DOI":"10.1167\/iovs.02-0901","volume":"44","author":"Rotstein NP","year":"2003","journal-title":"Investig Ophthalmol Vis Sci"},{"key":"CIT0052","first-page":"113","volume":"7","author":"Salvati S","year":"1996","journal-title":"Effect of dietary oils on brain enzymatic activities (2'-3'-cyclic nucleotide 3'-phos-phodiesterase and acetylcholinesterase) and muscarinic receptor sites in growing rats. J Nutr Biochem"}],"container-title":["Free Radical Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/10715760500145069","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,4]],"date-time":"2023-05-04T10:55:22Z","timestamp":1683197722000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/full\/10.1080\/10715760500145069"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,8]]},"references-count":47,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2009,7,7]]},"published-print":{"date-parts":[[2005,8]]}},"alternative-id":["10.1080\/10715760500145069"],"URL":"https:\/\/doi.org\/10.1080\/10715760500145069","relation":{},"ISSN":["1071-5762","1029-2470"],"issn-type":[{"value":"1071-5762","type":"print"},{"value":"1029-2470","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,8]]}}}