{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T23:08:20Z","timestamp":1793747300930,"version":"4.6.1"},"reference-count":45,"publisher":"Informa UK Limited","issue":"1","license":[{"start":{"date-parts":[[2017,1,1]],"date-time":"2017-01-01T00:00:00Z","timestamp":1483228800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/Licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Drug Delivery"],"published-print":{"date-parts":[[2017,1,1]]},"DOI":"10.1080\/10717544.2017.1279237","type":"journal-article","created":{"date-parts":[[2017,2,9]],"date-time":"2017-02-09T11:02:40Z","timestamp":1486638160000},"page":"558-568","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":43,"title":["Marked augmentation of PLGA nanoparticle-induced metabolically beneficial impact of \u03b3-oryzanol on fuel dyshomeostasis in genetically obese-diabetic\n                    <i>ob\/ob<\/i>\n                    mice"],"prefix":"10.1080","volume":"24","author":[{"given":"Chisayo","family":"Kozuka","sequence":"first","affiliation":[{"name":"Division of Endocrinology, Diabetes and Metabolism, Hematology, Rheumatology (Second Department of Internal Medicine), Graduate School of Medicine and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chigusa","family":"Shimizu-Okabe","sequence":"additional","affiliation":[{"name":"Department of Molecular Anatomy, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chitoshi","family":"Takayama","sequence":"additional","affiliation":[{"name":"Department of Molecular Anatomy, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaku","family":"Nakano","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine and"},{"name":"Department of Cardiovascular Research, Development, and Translational Medicine, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidetaka","family":"Morinaga","sequence":"additional","affiliation":[{"name":"SENTAN Pharma Inc., Fukuoka, Japan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayano","family":"Kinjo","sequence":"additional","affiliation":[{"name":"SENTAN Pharma Inc., Fukuoka, Japan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kotaro","family":"Fukuda","sequence":"additional","affiliation":[{"name":"SENTAN Pharma Inc., Fukuoka, Japan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asuka","family":"Kamei","sequence":"additional","affiliation":[{"name":"Kanagawa Academy of Science and Technology, Kanagawa, Japan, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihito","family":"Yasuoka","sequence":"additional","affiliation":[{"name":"Kanagawa Academy of Science and Technology, Kanagawa, Japan, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Kondo","sequence":"additional","affiliation":[{"name":"Kanagawa Academy of Science and Technology, Kanagawa, Japan, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keiko","family":"Abe","sequence":"additional","affiliation":[{"name":"Kanagawa Academy of Science and Technology, Kanagawa, Japan, and"},{"name":"Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kensuke","family":"Egashira","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine and"},{"name":"Department of Cardiovascular Research, Development, and Translational Medicine, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan,"},{"name":"SENTAN Pharma Inc., Fukuoka, Japan,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroaki","family":"Masuzaki","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Diabetes and Metabolism, Hematology, Rheumatology (Second Department of Internal Medicine), Graduate School of Medicine and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2017,2,9]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.52.7.1716"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2004.07.055"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.110.157032"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1111\/wrr.12404"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2012.01.043"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.R036012"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.1956.tb12060.x"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1038\/scientificamerican0211-40"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1002\/glia.22580"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2010.02.034"},{"key":"CIT0011","doi-asserted-by":"crossref","first-page":"e003872","DOI":"10.1161\/JAHA.116.003872","volume":"5","author":"Ishikita A","year":"2016","journal-title":"J Am Heart Assoc"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0065732"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.5551\/jat.35113"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1111\/bph.13236"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1210\/en.2014-1748"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.2337\/db11-1767"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1016\/j.orcp.2013.02.003"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.108.182584"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2009.01.063"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0504978102"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1016\/S0928-0987(97)10007-0"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1016\/0378-4347(87)80376-6"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1038\/414821a"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2014.00190"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1014296"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2010.215665"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.2217\/nnm-2016-0022"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1023\/A:1015818504906"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.5001\/omj.2012.68"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2008.04.011"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1126\/science.1103160"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1016\/j.tem.2015.07.002"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1002\/jps.21158"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1016\/j.tem.2015.05.007"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1264\/jsme2.ME12115"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2005.11.003"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1016\/j.nano.2010.02.002"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.1023\/A:1018876308346"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114513002432"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.1001\/archinternmed.2010.109"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1093\/intimm\/dxh073"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.1046\/j.1524-475X.2003.11621.x"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.1038\/nature05414"},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2014.09.039"},{"key":"CIT0045","first-page":"e2096","author":"Zmuda EJ","year":"2011","journal-title":"J Vis Exp"}],"container-title":["Drug Delivery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/tandfonline.com\/doi\/pdf\/10.1080\/10717544.2017.1279237","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/10717544.2017.1279237","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,26]],"date-time":"2022-08-26T04:53:59Z","timestamp":1661489639000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/10717544.2017.1279237"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1,1]]},"references-count":45,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1,1]]}},"alternative-id":["10.1080\/10717544.2017.1279237"],"URL":"https:\/\/doi.org\/10.1080\/10717544.2017.1279237","relation":{},"ISSN":["1071-7544","1521-0464"],"issn-type":[{"value":"1071-7544","type":"print"},{"value":"1521-0464","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1,1]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=idrd20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=idrd20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2016-11-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-01-01","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-01-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-02-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}