{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T14:30:50Z","timestamp":1792679450978,"version":"4.5.0"},"reference-count":53,"publisher":"Informa UK Limited","issue":"1","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["NIH EY020617"],"award-info":[{"award-number":["NIH EY020617"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["P30EY022589"],"award-info":[{"award-number":["P30EY022589"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Drug Delivery"],"published-print":{"date-parts":[[2018,1,1]]},"DOI":"10.1080\/10717544.2018.1486474","type":"journal-article","created":{"date-parts":[[2018,7,11]],"date-time":"2018-07-11T23:23:52Z","timestamp":1531351432000},"page":"1537-1545","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":19,"title":["Porous silicon based intravitreal platform for dual-drug loading and controlled release towards synergistic therapy"],"prefix":"10.1080","volume":"25","author":[{"given":"David","family":"Warther","sequence":"first","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of California, San Diego, CA, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Xiao","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Jacobs Retina Center at Shiley Eye Institute, University of California, San Diego, CA, USA;"},{"name":"Provincial Hospital Affiliated to Shandong University, Jinan City, Shandong Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fangting","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Jacobs Retina Center at Shiley Eye Institute, University of California, San Diego, CA, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuqin","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Jacobs Retina Center at Shiley Eye Institute, University of California, San Diego, CA, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3271-2518","authenticated-orcid":false,"given":"Kristyn","family":"Huffman","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Jacobs Retina Center at Shiley Eye Institute, University of California, San Diego, CA, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William R.","family":"Freeman","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Jacobs Retina Center at Shiley Eye Institute, University of California, San Diego, CA, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Sailor","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of California, San Diego, CA, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingyun","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Jacobs Retina Center at Shiley Eye Institute, University of California, San Diego, CA, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2018,7,11]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199412013312203"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2008.03.017"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1005073"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.16-19729"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2017.01.021"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.3928\/15428877-20100303-06"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1984.01040030470029"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2014-305684"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.5772\/50338"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2007.133587"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.12-11172"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2013.10.019"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2017.09.011"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(01)01269-7"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-005-0017-4"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-2952(98)00307-4"},{"key":"CIT0017","first-page":"119","volume":"8","author":"Grossniklaus HE","year":"2002","journal-title":"Mol Vis"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1089\/jop.2012.0205"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djp052"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.15-18559"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.15-16526"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2014.01.003"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2012.01.008"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.02-1178"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1007\/s004170050284"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.3928\/15428877-20100924-01"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-128X(00)00235-X"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2013-303513"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0002675"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1080\/17425247.2017.1317245"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1992.01080140115038"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0000000000001004"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2013.09.001"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2013.03.046"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1007\/BF02134142"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.2089"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.2147\/OPTH.S115546"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.10-5996"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2012.01.020"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.2217\/nnm.14.97"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1080\/02652040802312572"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.3109\/08820538.2011.570849"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2011-301005"},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2015.01.021"},{"key":"CIT0045","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2014.11.002"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2010.196"},{"key":"CIT0047","first-page":"1351","volume":"123","author":"Wells JA","year":"2016","journal-title":"a comparative effectiveness randomized clinical trial. Ophthalmology"},{"key":"CIT0048","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(98)00115-9"},{"key":"CIT0049","doi-asserted-by":"publisher","DOI":"10.1007\/BF02308080"},{"key":"CIT0050","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemmater.7b03461"},{"key":"CIT0051","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.7b00944"},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.1248\/bpb.29.1999"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0000000000000081"}],"container-title":["Drug Delivery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/10717544.2018.1486474","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/10717544.2018.1486474","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,6]],"date-time":"2020-09-06T11:57:18Z","timestamp":1599393438000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/10717544.2018.1486474"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,1]]},"references-count":53,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,1,1]]}},"alternative-id":["10.1080\/10717544.2018.1486474"],"URL":"https:\/\/doi.org\/10.1080\/10717544.2018.1486474","relation":{},"ISSN":["1071-7544","1521-0464"],"issn-type":[{"value":"1071-7544","type":"print"},{"value":"1521-0464","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1,1]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=idrd20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=idrd20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2018-05-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-05-30","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-06-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-07-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}