{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:56:39Z","timestamp":1792785399933,"version":"4.5.0"},"reference-count":39,"publisher":"Informa UK Limited","issue":"1","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"National Key Research and Development Plan","award":["2016YFC1101201"],"award-info":[{"award-number":["2016YFC1101201"]}]},{"DOI":"10.13039\/501100001809","name":"the National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31901735"],"award-info":[{"award-number":["31901735"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"the National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31600807"],"award-info":[{"award-number":["31600807"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"the Provincial Natural Science Foundation of Zhejiang, China","award":["LY19H120002"],"award-info":[{"award-number":["LY19H120002"]}]},{"DOI":"10.13039\/100007835","name":"Wenzhou Medical University","doi-asserted-by":"publisher","award":["K171204"],"award-info":[{"award-number":["K171204"]}],"id":[{"id":"10.13039\/100007835","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Drug Delivery"],"published-print":{"date-parts":[[2020,1]]},"DOI":"10.1080\/10717544.2020.1748759","type":"journal-article","created":{"date-parts":[[2020,4,30]],"date-time":"2020-04-30T05:14:40Z","timestamp":1588223680000},"page":"556-564","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":38,"title":["Localized co-delivery of CNTF and FK506 using a thermosensitive hydrogel for retina ganglion cells protection after traumatic optic nerve injury"],"prefix":"10.1080","volume":"27","author":[{"given":"Dongmei","family":"Wang","sequence":"first","affiliation":[{"name":"School of Ophthalmology &amp; Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengmeng","family":"Luo","sequence":"additional","affiliation":[{"name":"School of Ophthalmology &amp; Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, China"},{"name":"Wenzhou Institute, University of Chinese Academy of Science, Wenzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baoshan","family":"Huang","sequence":"additional","affiliation":[{"name":"School of Ophthalmology &amp; Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, China"},{"name":"Wenzhou Institute, University of Chinese Academy of Science, Wenzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wa","family":"Gao","sequence":"additional","affiliation":[{"name":"School of Ophthalmology &amp; Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Jiang","sequence":"additional","affiliation":[{"name":"School of Ophthalmology &amp; Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Li","sequence":"additional","affiliation":[{"name":"School of Ophthalmology &amp; Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, China"},{"name":"State Key Laboratory of Ophthalmology, Optometry and Visual Science, Wenzhou Medical University, Wenzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6592-1682","authenticated-orcid":false,"given":"Kaihui","family":"Nan","sequence":"additional","affiliation":[{"name":"School of Ophthalmology &amp; Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, China"},{"name":"State Key Laboratory of Ophthalmology, Optometry and Visual Science, Wenzhou Medical University, Wenzhou, China"},{"name":"Wenzhou Institute, University of Chinese Academy of Science, Wenzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8284-9988","authenticated-orcid":false,"given":"Sen","family":"Lin","sequence":"additional","affiliation":[{"name":"School of Ophthalmology &amp; Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, China"},{"name":"State Key Laboratory of Ophthalmology, Optometry and Visual Science, Wenzhou Medical University, Wenzhou, China"},{"name":"Wenzhou Institute, University of Chinese Academy of Science, Wenzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2020,4,30]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2011.11.002"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2015.11.036"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2018.11.006"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2009.07.019"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn2038"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-008045046-9.01018-4"},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/IJG.0b013e3181d787e5"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2017.04.109"},{"key":"e_1_3_2_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2010.02.026"},{"key":"e_1_3_2_11_1","first-page":"1859","article-title":"Microglial cell activation in traumatic optic neuropathy (TON)","volume":"52","author":"Fatteh N","year":"2011","unstructured":"Fatteh N, Ibrahim A, Liou G. (2011). Microglial cell activation in traumatic optic neuropathy (TON). Inves Ophth Vis Sci 52:1859.","journal-title":"Inves Ophth Vis Sci"},{"key":"e_1_3_2_12_1","doi-asserted-by":"publisher","DOI":"10.1523\/ENEURO.0331-16.2016"},{"key":"e_1_3_2_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2012.06.005"},{"key":"e_1_3_2_14_1","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2011.1928"},{"key":"e_1_3_2_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/jb\/mvw009"},{"key":"e_1_3_2_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2005.02.019"},{"key":"e_1_3_2_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2009.09.004"},{"key":"e_1_3_2_18_1","first-page":"1442","article-title":"Chitosan temperature-sensitive gel loaded with drug microspheres has excellent effectiveness, biocompatibility and safety as an ophthalmic drug delivery system","volume":"15","author":"Kong X","year":"2017","unstructured":"Kong X, Xu W, Zhang C, et\u00a0al. (2017). Chitosan temperature-sensitive gel loaded with drug microspheres has excellent effectiveness, biocompatibility and safety as an ophthalmic drug delivery system. Exp Ther Med 15:1442\u20131448.","journal-title":"Exp Ther Med"},{"key":"e_1_3_2_19_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsbiomaterials.8b00803"},{"key":"e_1_3_2_20_1","doi-asserted-by":"publisher","DOI":"10.1039\/C5TB00736D"},{"key":"e_1_3_2_21_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.9b13851"},{"key":"e_1_3_2_22_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12274-017-1928-1"},{"key":"e_1_3_2_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10856-018-6149-y"},{"key":"e_1_3_2_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcn.2009.03.002"},{"key":"e_1_3_2_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00396-014-3276-y"},{"key":"e_1_3_2_26_1","first-page":"2500","article-title":"Tacrolimus reduces scar formation and promotes sciatic nerve regeneration","volume":"7","author":"Que J","year":"2012","unstructured":"Que J, Cao Q, Sui T. (2012). Tacrolimus reduces scar formation and promotes sciatic nerve regeneration. Neural Regen Res 7:2500\u20132506.","journal-title":"Neural Regen Res"},{"key":"e_1_3_2_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2013.56"},{"key":"e_1_3_2_28_1","first-page":"3460","article-title":"Retrograde axonal transport of BDNF in retinal ganglion cells is blocked by acute IOP elevation in rats","volume":"41","author":"Quigley HA","year":"2000","unstructured":"Quigley HA, McKinnon SJ, Zack DJ, et\u00a0al. (2000). Retrograde axonal transport of BDNF in retinal ganglion cells is blocked by acute IOP elevation in rats. Invest Ophth Vis Sci 41:3460\u20133466.","journal-title":"Invest Ophth Vis Sci"},{"key":"e_1_3_2_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0173(00)00028-X"},{"key":"e_1_3_2_30_1","doi-asserted-by":"publisher","DOI":"10.4103\/1673-5374.175038"},{"key":"e_1_3_2_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2019.05.004"},{"key":"e_1_3_2_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2017.07.017"},{"key":"e_1_3_2_33_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.8b13077"},{"key":"e_1_3_2_34_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.13-12683"},{"key":"e_1_3_2_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2011.11.031"},{"key":"e_1_3_2_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2017.05.003"},{"key":"e_1_3_2_37_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.5b00287"},{"key":"e_1_3_2_38_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00109-012-0925-9"},{"key":"e_1_3_2_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2014.06.005"},{"key":"e_1_3_2_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2014.09.094"}],"container-title":["Drug Delivery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/10717544.2020.1748759","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T09:06:27Z","timestamp":1719911187000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/10717544.2020.1748759"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,1]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1]]}},"alternative-id":["10.1080\/10717544.2020.1748759"],"URL":"https:\/\/doi.org\/10.1080\/10717544.2020.1748759","relation":{},"ISSN":["1071-7544","1521-0464"],"issn-type":[{"value":"1071-7544","type":"print"},{"value":"1521-0464","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,1]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=idrd20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=idrd20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2019-12-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-03-25","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-04-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}