{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T12:36:36Z","timestamp":1780576596969,"version":"3.54.1"},"reference-count":53,"publisher":"Informa UK Limited","issue":"3","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Journal of Receptors and Signal Transduction"],"published-print":{"date-parts":[[2017,5,4]]},"DOI":"10.1080\/10799893.2016.1212376","type":"journal-article","created":{"date-parts":[[2016,8,3]],"date-time":"2016-08-03T01:58:57Z","timestamp":1470189537000},"page":"224-238","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":13,"title":["Novel virtual lead identification in the discovery of hematopoietic cell kinase (HCK) inhibitors: application of 3D QSAR and molecular dynamics simulation"],"prefix":"10.1080","volume":"37","author":[{"given":"Rohit","family":"Bavi","sequence":"first","affiliation":[{"name":"Division of Applied Life Science (BK21 Plus Program), Systems and Synthetic Agrobiotech Center (SSAC), Plant Molecular Biology and Biotechnology Research Center (PMBBRC), Research Institute of Natural Science (RINS), Gyeongsang National University (GNU), Jinju, Republic of Korea;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raj","family":"Kumar","sequence":"additional","affiliation":[{"name":"Division of Applied Life Science (BK21 Plus Program), Systems and Synthetic Agrobiotech Center (SSAC), Plant Molecular Biology and Biotechnology Research Center (PMBBRC), Research Institute of Natural Science (RINS), Gyeongsang National University (GNU), Jinju, Republic of Korea;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shailima","family":"Rampogu","sequence":"additional","affiliation":[{"name":"Division of Applied Life Science (BK21 Plus Program), Systems and Synthetic Agrobiotech Center (SSAC), Plant Molecular Biology and Biotechnology Research Center (PMBBRC), Research Institute of Natural Science (RINS), Gyeongsang National University (GNU), Jinju, Republic of Korea;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongseong","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Science Education, Kyungnam University, Masan, Republic of Korea;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong Jung","family":"Kwon","sequence":"additional","affiliation":[{"name":"Department of Chemical Engineering, Kangwon National University, Chunchon, Republic of Korea;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seok Ju","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, College of Medicine, Busan Paik Hospital, Inje University, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keun Woo","family":"Lee","sequence":"additional","affiliation":[{"name":"Division of Applied Life Science (BK21 Plus Program), Systems and Synthetic Agrobiotech Center (SSAC), Plant Molecular Biology and Biotechnology Research Center (PMBBRC), Research Institute of Natural Science (RINS), Gyeongsang National University (GNU), Jinju, Republic of Korea;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2016,8,2]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1126\/science.1075762"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2009.129"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1038\/385602a0"},{"key":"CIT0004","first-page":"475","volume":"4","author":"Silverman L","year":"1993","journal-title":"Cell Growth Differ"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.15.7.3507"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2004.09.171"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1208081"},{"key":"CIT0008","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1182\/blood.V77.4.726.726","volume":"77","author":"Willman CL","year":"1991","journal-title":"Blood"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M201212200"},{"key":"CIT0010","first-page":"3589","volume":"56","author":"Danhauser-Riedl S","year":"1996","journal-title":"Cancer Res"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.C000126200"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2402778"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/cdf562"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcb.2008.03.008"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V96.10.3343"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.52.33260"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2014.02.017"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-04-038943"},{"key":"CIT0019","first-page":"534","volume":"90","author":"Martinelli G","year":"2005","journal-title":"Haematologica"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1038\/nrc2126"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4690-8-3"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.29.17899"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1021\/cb900195c"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2010.01.008"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.1990"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.2174\/0929867013372481"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1021\/jm010360c"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2007.11.014"},{"key":"CIT0029","volume-title":"The principle of experimentation illustrated by a psycho-physical expe, Chapter II","author":"Fischer R.","year":"1966","edition":"8"},{"key":"CIT0030","doi-asserted-by":"crossref","first-page":"S4","DOI":"10.1186\/1471-2105-12-S14-S4","volume":"12","author":"John S","year":"2011","journal-title":"BMC Bioinformatics"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1038\/aps.2015.17"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1021\/ci049844i"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-409X(00)00129-0"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.1996.0897"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2006.08.132"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.20291"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.21816"},{"key":"CIT0038","doi-asserted-by":"crossref","first-page":"014101","DOI":"10.1063\/1.2408420","volume":"126","author":"Bussi G","year":"2007","journal-title":"J Chem Phys"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1063\/1.328693"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-987X(199709)18:12<1463::AID-JCC4>3.0.CO;2-H"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.540130805"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.1063\/1.464397"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.1016\/0263-7855(96)00018-5"},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.1021\/ci100275a"},{"key":"CIT0045","doi-asserted-by":"crossref","first-page":"e46902","DOI":"10.1371\/journal.pone.0046902","volume":"7","author":"Spiliotopoulos D","year":"2012","journal-title":"PLoS One"},{"key":"CIT0046","doi-asserted-by":"crossref","first-page":"e0147190","DOI":"10.1371\/journal.pone.0147190","volume":"11","author":"Bavi R","year":"2016","journal-title":"PLoS One"},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiomed.2016.06.005"},{"key":"CIT0048","doi-asserted-by":"publisher","DOI":"10.1002\/minf.201100135"},{"key":"CIT0049","doi-asserted-by":"publisher","DOI":"10.1023\/A:1007996124545"},{"key":"CIT0050","doi-asserted-by":"publisher","DOI":"10.1021\/jm061277y"},{"key":"CIT0051","doi-asserted-by":"crossref","first-page":"D1075","DOI":"10.1093\/nar\/gkt978","volume":"42","author":"Wang Y","year":"2014","journal-title":"Nucleic Acids Res"},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.1110\/ps.03129704"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.1021\/jm000040d"}],"container-title":["Journal of Receptors and Signal Transduction"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/10799893.2016.1212376","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,5]],"date-time":"2020-09-05T17:51:16Z","timestamp":1599328276000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/10799893.2016.1212376"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,2]]},"references-count":53,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,5,4]]}},"alternative-id":["10.1080\/10799893.2016.1212376"],"URL":"https:\/\/doi.org\/10.1080\/10799893.2016.1212376","relation":{},"ISSN":["1079-9893","1532-4281"],"issn-type":[{"value":"1079-9893","type":"print"},{"value":"1532-4281","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,2]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=irst20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=irst20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2016-05-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-06-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-08-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}