{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T22:48:53Z","timestamp":1787006933598,"version":"build-2736575974"},"reference-count":32,"publisher":"Informa UK Limited","issue":"5-6","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Journal of Receptors and Signal Transduction"],"published-print":{"date-parts":[[2019,11,2]]},"DOI":"10.1080\/10799893.2019.1690509","type":"journal-article","created":{"date-parts":[[2019,11,22]],"date-time":"2019-11-22T05:35:20Z","timestamp":1574400920000},"page":"415-433","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":20,"title":["Molecular dynamics guided insight, binding free energy calculations and pharmacophore-based virtual screening for the identification of potential VEGFR2 inhibitors"],"prefix":"10.1080","volume":"39","author":[{"given":"Ekta","family":"Rathi","sequence":"first","affiliation":[{"name":"Department of Pharmaceutical Chemistry, Manipal College of Pharmaceutical Sciences, Manipal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avinash","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Chemistry, Manipal College of Pharmaceutical Sciences, Manipal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suvarna G.","family":"Kini","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Chemistry, Manipal College of Pharmaceutical Sciences, Manipal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2019,11,22]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1021\/jm301085w"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.9-suppl_1-2"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2009.03.091"},{"issue":"2","key":"CIT0004","first-page":"51","volume":"80","author":"Ziello JE","year":"2007","journal-title":"Yale J Biol Med"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1016\/S0968-0004(03)00193-2"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1038\/nm0603-669"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1038\/nchembio799"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1021\/jm400072p"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2015.04.005"},{"key":"CIT0010","first-page":"140","volume":"61","author":"Lu T","year":"2017","journal-title":"J Med Chem"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2006.09.015"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1021\/ci400429g"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.2174\/1568026023393273"},{"issue":"2","key":"CIT0014","first-page":"405","volume":"13","author":"Ebadi A","year":"2014","journal-title":"Iran J Pharm Res"},{"key":"CIT0015","doi-asserted-by":"crossref","unstructured":"Mctigue M, William B, Chen JH, et\u00a0al. Molecular conformations, interactions, and properties associated with drug efficiency and clinical performance among VEGFR TK inhibitors. Proc Natl Acad Sci USA. 2012;109(45):18281\u201318289.","DOI":"10.1073\/pnas.1207759109"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1007\/s10822-013-9644-8"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2015.08.045"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-0285.2006.00384.x"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.1007\/s00044-014-1057-2"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1021\/ci3001277"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jcim.5b00559"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1021\/ci010056s"},{"key":"CIT0023","first-page":"1219","volume":"34","author":"Nicklaus MC","year":"2005","journal-title":"J Chem Inf Model"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1021\/jm051256o"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1021\/jm0306430"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1517\/17460441.2015.1032936"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1186\/2193-1801-2-353"},{"key":"CIT0028","first-page":"37","volume":"8","author":"Gelpi J","year":"2015","journal-title":"Adv Appl Bioinform Chem"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1145\/1188455.1188544"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1021\/ci100275a"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.21666"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1021\/jm060522a"}],"container-title":["Journal of Receptors and Signal Transduction"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/10799893.2019.1690509","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,12,29]],"date-time":"2019-12-29T19:48:06Z","timestamp":1577648886000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/10799893.2019.1690509"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11,2]]},"references-count":32,"journal-issue":{"issue":"5-6","published-print":{"date-parts":[[2019,11,2]]}},"alternative-id":["10.1080\/10799893.2019.1690509"],"URL":"https:\/\/doi.org\/10.1080\/10799893.2019.1690509","relation":{},"ISSN":["1079-9893","1532-4281"],"issn-type":[{"value":"1079-9893","type":"print"},{"value":"1532-4281","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11,2]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=irst20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=irst20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2019-06-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-10-31","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-11-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-11-22","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}