{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,26]],"date-time":"2025-11-26T22:06:46Z","timestamp":1764194806115,"version":"3.40.5"},"reference-count":52,"publisher":"Informa UK Limited","issue":"4","funder":[{"name":"State of S\u00e3o Paulo Research Foundation (FAPESP-Brazil","award":["2013\/08617-7","2016\/22065-5","2017\/20384-9","2018\/25994-2"],"award-info":[{"award-number":["2013\/08617-7","2016\/22065-5","2017\/20384-9","2018\/25994-2"]}]},{"name":"National Council for Scientific and Technological Development (CNPq-Brazil","award":["301832\/2017-0"],"award-info":[{"award-number":["301832\/2017-0"]}]},{"name":"ANID Becas Chile\/Doctorado en el extranjero\/2020","award":["72210489"],"award-info":[{"award-number":["72210489"]}]},{"name":"Coordination of Improvement of Higher Education Personnel (CAPES-Brazil","award":["001"],"award-info":[{"award-number":["001"]}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Preparative Biochemistry &amp; Biotechnology"],"published-print":{"date-parts":[[2024,4]]},"DOI":"10.1080\/10826068.2023.2249100","type":"journal-article","created":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T10:50:08Z","timestamp":1694515808000},"page":"503-513","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":3,"title":["PEGylation versus glycosylation: effect on the thermodynamics and thermostability of crisantaspase"],"prefix":"10.1080","volume":"54","author":[{"given":"Karin","family":"Torres\u2010Obreque","sequence":"first","affiliation":[{"name":"Department of Biochemical and Pharmaceutical Technology, University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo Krebs","family":"Kleingesinds","sequence":"additional","affiliation":[{"name":"Department of Biochemical and Pharmaceutical Technology, University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jo\u00e3o H. P. M.","family":"Santos","sequence":"additional","affiliation":[{"name":"Department of Biochemical and Pharmaceutical Technology, University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gustavo","family":"Carretero","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Institute of Chemistry, University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jheniffer","family":"Rabelo","sequence":"additional","affiliation":[{"name":"Department of Biochemical and Pharmaceutical Technology, University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Attilio","family":"Converti","sequence":"additional","affiliation":[{"name":"Department of Civil, Chemical and Environmental Engineering, Pole of Chemical Engineering, University of Genoa, Genoa, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3385-047X","authenticated-orcid":false,"given":"Gisele","family":"Monteiro","sequence":"additional","affiliation":[{"name":"Department of Biochemical and Pharmaceutical Technology, University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr","given":"Adalberto","family":"Pessoa","sequence":"additional","affiliation":[{"name":"Department of Biochemical and Pharmaceutical Technology, University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlota O.","family":"Rangel-Yagui","sequence":"additional","affiliation":[{"name":"Department of Biochemical and Pharmaceutical Technology, University of S\u00e3o Paulo, S\u00e3o Paulo, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2023,9,12]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/FEBS.16404"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0022154"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms3901"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.01568-17"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1359-6446(05)03575-0"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.DRUDIS.2021.08.009"},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.1590\/s2175-97902018000001009"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0211951"},{"key":"e_1_3_2_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.IJPHARM.2022.121863"},{"key":"e_1_3_2_11_1","doi-asserted-by":"publisher","DOI":"10.1021\/ACS.BIOMAC.0C00517"},{"key":"e_1_3_2_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.ADDR.2021.114079"},{"key":"e_1_3_2_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.procbio.2023.06.006"},{"key":"e_1_3_2_14_1","doi-asserted-by":"publisher","DOI":"10.3389\/FIMMU.2018.02485\/BIBTEX"},{"key":"e_1_3_2_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bej.2020.107516"},{"key":"e_1_3_2_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bej.2020.107750"},{"key":"e_1_3_2_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/J.IJBIOMAC.2023.123440"},{"key":"e_1_3_2_18_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0091659"},{"key":"e_1_3_2_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2015.07.043"},{"key":"e_1_3_2_20_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bty1011"},{"key":"e_1_3_2_21_1","doi-asserted-by":"publisher","DOI":"10.1373\/49.5.838"},{"key":"e_1_3_2_22_1","doi-asserted-by":"publisher","DOI":"10.1039\/C9TB00590K"},{"key":"e_1_3_2_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/bmb.21127"},{"key":"e_1_3_2_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11274-019-2731-9"},{"key":"e_1_3_2_25_1","doi-asserted-by":"publisher","DOI":"10.3390\/PHARMACEUTICS14091819\/S1"},{"key":"e_1_3_2_26_1","doi-asserted-by":"publisher","DOI":"10.1097\/00043426-200404000-00002"},{"key":"e_1_3_2_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1582-4934.2012.01547.x"},{"key":"e_1_3_2_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature25465"},{"key":"e_1_3_2_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbiotec.2006.07.037"},{"key":"e_1_3_2_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10637-014-0102-9"},{"key":"e_1_3_2_31_1","first-page":"2423","article-title":"Asparaginases: Biochemical Pharmacology and Modes of Drug Resistance","volume":"32","author":"Avramis V. I.","year":"2012","unstructured":"Avramis, V. I. Asparaginases: Biochemical Pharmacology and Modes of Drug Resistance. Anticancer Res. 2012, 32, 2423\u20132437.","journal-title":"Anticancer Res."},{"key":"e_1_3_2_32_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M116.728485"},{"key":"e_1_3_2_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/bab.1723"},{"key":"e_1_3_2_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bej.2021.108083"},{"key":"e_1_3_2_35_1","doi-asserted-by":"publisher","DOI":"10.1099\/00221287-76-1-85"},{"key":"e_1_3_2_36_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1500851112"},{"key":"e_1_3_2_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/bit.10124"},{"key":"e_1_3_2_38_1","volume-title":"Energetics and Kinetics in Biotechnology","author":"Roels J.","year":"1983","unstructured":"Roels, J. Energetics and Kinetics in Biotechnology; Elsevier Biomedical Press: New York, 1983."},{"key":"e_1_3_2_39_1","doi-asserted-by":"publisher","DOI":"10.1021\/ed019p249.1"},{"key":"e_1_3_2_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bej.2013.09.016"},{"key":"e_1_3_2_41_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10529-016-2083-6"},{"key":"e_1_3_2_42_1","doi-asserted-by":"publisher","DOI":"10.1107\/S0907444902019443"},{"key":"e_1_3_2_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12033-014-9766-9"},{"key":"e_1_3_2_44_1","doi-asserted-by":"publisher","DOI":"10.1021\/bc00027a008"},{"key":"e_1_3_2_45_1","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/1298473"},{"key":"e_1_3_2_46_1","doi-asserted-by":"publisher","DOI":"10.5772\/66296"},{"key":"e_1_3_2_47_1","doi-asserted-by":"publisher","DOI":"10.1021\/ACS.JAFC.2C05712\/ASSET\/IMAGES\/LARGE\/JF2C05712_0010.JPEG"},{"key":"e_1_3_2_48_1","doi-asserted-by":"publisher","DOI":"10.1007\/S00253-023-12443-1\/FIGURES\/5"},{"key":"e_1_3_2_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/febs.12906"},{"key":"e_1_3_2_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfoodeng.2020.109986"},{"key":"e_1_3_2_51_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0021624"},{"key":"e_1_3_2_52_1","doi-asserted-by":"publisher","DOI":"10.1002\/0471267295"},{"key":"e_1_3_2_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2836(92)90121-Y"}],"container-title":["Preparative Biochemistry &amp; Biotechnology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/10826068.2023.2249100","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,31]],"date-time":"2024-03-31T23:10:16Z","timestamp":1711926616000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/10826068.2023.2249100"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,12]]},"references-count":52,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["10.1080\/10826068.2023.2249100"],"URL":"https:\/\/doi.org\/10.1080\/10826068.2023.2249100","relation":{},"ISSN":["1082-6068","1532-2297"],"issn-type":[{"type":"print","value":"1082-6068"},{"type":"electronic","value":"1532-2297"}],"subject":[],"published":{"date-parts":[[2023,9,12]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=lpbb20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=lpbb20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2023-09-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}