{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T01:46:51Z","timestamp":1780710411183,"version":"3.54.1"},"reference-count":71,"publisher":"Informa UK Limited","issue":"7","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Pharmaceutical Development and Technology"],"published-print":{"date-parts":[[2019,8,9]]},"DOI":"10.1080\/10837450.2019.1602631","type":"journal-article","created":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T11:18:16Z","timestamp":1554117496000},"page":"824-838","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":15,"title":["Formulation of sustained release bioadhesive minitablets containing solid dispersion of levofloxacin for once daily ocular use"],"prefix":"10.1080","volume":"24","author":[{"given":"Ahmed","family":"Abd El-Bary","sequence":"first","affiliation":[{"name":"Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Howida","family":"Kamal Ibrahim","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Balqees Saeed","family":"Haza\u2019a","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4377-3420","authenticated-orcid":false,"given":"Ibrahim","family":"Al Sharabi","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt;"},{"name":"Department of Pharmaceutics, College of Pharmacy, King Khalid University, Abha, Kingdom of Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2019,4,26]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.3109\/10837450903479988"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1016\/0378-5173(94)00273-8"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-5173(02)00059-5"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpb.2008.09.028"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-5173(03)00288-6"},{"key":"CIT0006","volume-title":"Aulton\u2019s pharmaceutics: the design and manufacture of medicines","author":"Aulton ME","year":"2017","edition":"5"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-47691-9_1"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1016\/j.powtec.2011.12.046"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1007\/s13346-011-0018-2"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.3109\/03639049009104410"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.3109\/03639041003718030"},{"key":"CIT0012","volume-title":"Strategies to modify the drug release from pharmaceutical systems","author":"Bruschi ML","year":"2015"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2011.08.129"},{"key":"CIT0014","volume-title":"Stability study of levofloxacin 750\u2009mg\/30\u2009ml IV vials","author":"CARAS.","year":"2012"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2008.02.011"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpb.2006.09.001"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1007\/s10973-005-7131-8"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-3659(96)01523-4"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2015.09.064"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.3109\/10837450903262017"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2009.04.038"},{"key":"CIT0022","first-page":"377","volume":"82","author":"Draize JH","year":"1944","journal-title":"J Pharmacol Exp Ther"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.3109\/03639045.2015.1070171"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2004.07.033"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsps.2014.02.009"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1016\/0168-3659(95)00086-0"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.3109\/10837450902967947"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1002\/jps.23200"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-5173(00)00508-1"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.3109\/1061186X.2010.504268"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.4103\/0975-7406.149810"},{"key":"CIT0032","first-page":"155","volume":"2","author":"Hamzah MM","year":"2010","journal-title":"Drug Invent Today"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1208\/pt070116"},{"key":"CIT0034","volume-title":"Stability testing of new drug substances and products Q1A (R2)","author":"ICH","year":"2003"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1081\/DDC-120003860"},{"key":"CIT0036","first-page":"1","author":"Katara R","year":"2018","journal-title":"Pharm Dev Technol"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-3659(01)00441-2"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-3659(98)00122-9"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1080\/10837450.2016.1193191"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1099-0518(19990701)37:13<2061::AID-POLA20>3.0.CO;2-Y"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2005.07.005"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.1002\/ddr.20317"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.3109\/10717544.2010.509366"},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.3109\/03639048309048545"},{"key":"CIT0045","first-page":"665","volume":"3","author":"Mohamed MI","year":"2011","journal-title":"J Chem Pharm Res"},{"key":"CIT0046","first-page":"64","volume":"20","author":"Moore JW","year":"1996","journal-title":"Pharm Technol"},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1111\/jphp.12131"},{"key":"CIT0048","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2006.02.038"},{"key":"CIT0049","doi-asserted-by":"publisher","DOI":"10.1023\/A:1016048021064"},{"key":"CIT0050","doi-asserted-by":"publisher","DOI":"10.1208\/s12249-009-9326-y"},{"key":"CIT0051","doi-asserted-by":"publisher","DOI":"10.1080\/10837450.2017.1328693"},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.1208\/pt0802045"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.2478\/v10007-012-0002-5"},{"key":"CIT0054","doi-asserted-by":"publisher","DOI":"10.1517\/17425247.2013.772977"},{"key":"CIT0055","doi-asserted-by":"publisher","DOI":"10.3109\/10717544.2010.509364"},{"key":"CIT0056","doi-asserted-by":"publisher","DOI":"10.1016\/0168-3659(87)90034-4"},{"key":"CIT0057","doi-asserted-by":"publisher","DOI":"10.1016\/0168-3659(87)90035-6"},{"key":"CIT0058","doi-asserted-by":"publisher","DOI":"10.1016\/0169-409X(95)00013-W"},{"key":"CIT0059","volume-title":"Handbook of pharmaceutical excipients","author":"Rowe RC","year":"2009"},{"key":"CIT0060","doi-asserted-by":"crossref","first-page":"600","DOI":"10.3109\/10837450.2015.1035728","volume":"21","author":"Saher O","year":"2016","journal-title":"Pharm Dev Technol"},{"key":"CIT0061","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2005.07.003"},{"key":"CIT0062","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2013.10.072"},{"key":"CIT0063","doi-asserted-by":"publisher","DOI":"10.1007\/BF03218364"},{"key":"CIT0064","doi-asserted-by":"publisher","DOI":"10.1081\/DDC-100101318"},{"key":"CIT0065","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2005.07.001"},{"key":"CIT0066","doi-asserted-by":"publisher","DOI":"10.1163\/156856201753395743"},{"key":"CIT0067","unstructured":"Test No. 405: Acute Eye Irritation\/Corrosion. 2017. OECD guidelines for the testing of chemicals, section 4. Paris, France: Organisation for Economic Cooperation and Development (OECD)."},{"key":"CIT0068","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2008.06.025"},{"key":"CIT0069","doi-asserted-by":"publisher","DOI":"10.1080\/10717540500459308"},{"key":"CIT0070","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2005.02.026"},{"key":"CIT0071","first-page":"57","volume-title":"Pharmacologic therapy of ocular disease","author":"Yavuz B","year":"2017"}],"container-title":["Pharmaceutical Development and Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/10837450.2019.1602631","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,5]],"date-time":"2020-12-05T04:03:28Z","timestamp":1607141008000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/10837450.2019.1602631"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,26]]},"references-count":71,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2019,6,4]]},"published-print":{"date-parts":[[2019,8,9]]}},"alternative-id":["10.1080\/10837450.2019.1602631"],"URL":"https:\/\/doi.org\/10.1080\/10837450.2019.1602631","relation":{},"ISSN":["1083-7450","1097-9867"],"issn-type":[{"value":"1083-7450","type":"print"},{"value":"1097-9867","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,26]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iphd20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iphd20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2017-10-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-03-29","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-03-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-04-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}