{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:56:56Z","timestamp":1792785416090,"version":"4.5.0"},"reference-count":72,"publisher":"Informa UK Limited","issue":"3","license":[{"start":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T00:00:00Z","timestamp":1780531200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T00:00:00Z","timestamp":1780531200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1080\/policies-text-data-mining"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["INST 58219\/40-1 FUGG"],"award-info":[{"award-number":["INST 58219\/40-1 FUGG"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["1117240, 70113041"],"award-info":[{"award-number":["1117240, 70113041"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"publisher","award":["(CANTAR) project NW21-062 \"Netzwerke 2021\""],"award-info":[{"award-number":["(CANTAR) project NW21-062 \"Netzwerke 2021\""]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"name":"German Research Foundation","award":["413326622, SFB1430"],"award-info":[{"award-number":["413326622, SFB1430"]}],"id":[{"id":"https:\/\/ror.org\/018mejw64","id-type":"ROR","asserted-by":"crossref"}]},{"name":"German Research Foundation","award":["424228829 and SFB1530"],"award-info":[{"award-number":["424228829 and SFB1530"]}],"id":[{"id":"https:\/\/ror.org\/018mejw64","id-type":"ROR","asserted-by":"crossref"}]},{"name":"German Research Foundation","award":["455784452, RE 2246\/17-1 \u2013 553375105"],"award-info":[{"award-number":["455784452, RE 2246\/17-1 \u2013 553375105"]}],"id":[{"id":"https:\/\/ror.org\/018mejw64","id-type":"ROR","asserted-by":"crossref"}]},{"name":"German Cancer Aid","award":["1117240, 70113041"],"award-info":[{"award-number":["1117240, 70113041"]}],"id":[{"id":"https:\/\/ror.org\/01wxdd722","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Mildred Scheel Nachwuchszentrum","award":["70113307"],"award-info":[{"award-number":["70113307"]}]},{"name":"German Ministry of Education and Research","award":["e:Med Consortium InCa"],"award-info":[{"award-number":["e:Med Consortium InCa"]}]},{"name":"German Ministry of Education and Research","award":["grant 01ZX1901 and 01ZX2201A"],"award-info":[{"award-number":["grant 01ZX1901 and 01ZX2201A"]}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Amyloid"],"published-print":{"date-parts":[[2026,7,3]]},"DOI":"10.1080\/13506129.2026.2679153","type":"journal-article","created":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T16:33:16Z","timestamp":1780590796000},"page":"381-395","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":1,"title":["RNA-based full length immunoglobulin light chain sequencing reveals lambda constant domain mutations with potential implications for thermodynamic stability in light chain amyloidosis"],"prefix":"10.1080","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-3341-4759","authenticated-orcid":false,"given":"Eyad","family":"Naser","sequence":"first","affiliation":[{"name":"Institute of Molecular Biology, University Duisburg-Essen","place":["Essen, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Oubari","sequence":"additional","affiliation":[{"name":"Department of Hematology and Stem Cell Transplantation, University Hospital Essen","place":["Essen, Essen, Germany"]},{"name":"West German Amyloidosis Center, University Hospital Essen","place":["Essen, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josefine","family":"Jakob","sequence":"additional","affiliation":[{"name":"Department of Medicine II, Hematology\/Oncology, Goethe University","place":["Frankfurt, Germany"]},{"name":"Frankfurt Cancer Institute (FCI), Goethe University","place":["Frankfurt am Main, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bj\u00f6rn","family":"H\u00e4upl","sequence":"additional","affiliation":[{"name":"Department of Medicine II, Hematology\/Oncology, Goethe University","place":["Frankfurt, Germany"]},{"name":"Frankfurt Cancer Institute (FCI), Goethe University","place":["Frankfurt am Main, Germany"]},{"name":"German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK)","place":["Heidelberg, Germany"]},{"name":"German Cancer Consortium (DKTK), partner site Frankfurt\/Mainz, a partnership between DKFZ and UCT Frankfurt-Marburg, Germany","place":["Frankfurt am Main, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bettina","family":"Budeus","sequence":"additional","affiliation":[{"name":"Medical Faculty, Institute for Cell Biology (Cancer Research), University Duisburg-Essen","place":["Essen, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernd","family":"Walkenfort","sequence":"additional","affiliation":[{"name":"Imaging Center Essen, Electron Microscopy Unit, Faculty of Medicine, University Duisburg-Essen","place":["Essen, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie","family":"Nowakowski","sequence":"additional","affiliation":[{"name":"Institute of Molecular Biology, University Duisburg-Essen","place":["Essen, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriele","family":"Hessler","sequence":"additional","affiliation":[{"name":"Institute of Molecular Biology, University Duisburg-Essen","place":["Essen, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudine","family":"K\u00fchn","sequence":"additional","affiliation":[{"name":"Institute of Molecular Biology, University Duisburg-Essen","place":["Essen, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mike","family":"Hasenberg","sequence":"additional","affiliation":[{"name":"Imaging Center Essen, Electron Microscopy Unit, Faculty of Medicine, University Duisburg-Essen","place":["Essen, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Oellerich","sequence":"additional","affiliation":[{"name":"Department of Medicine II, Hematology\/Oncology, Goethe University","place":["Frankfurt, Germany"]},{"name":"Frankfurt Cancer Institute (FCI), Goethe University","place":["Frankfurt am Main, Germany"]},{"name":"German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK)","place":["Heidelberg, Germany"]},{"name":"German Cancer Consortium (DKTK), partner site Frankfurt\/Mainz, a partnership between DKFZ and UCT Frankfurt-Marburg, Germany","place":["Frankfurt am Main, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans Christian","family":"Reinhardt","sequence":"additional","affiliation":[{"name":"Department of Hematology and Stem Cell Transplantation, University Hospital Essen","place":["Essen, Essen, Germany"]},{"name":"West German Cancer Center, University Hospital Essen","place":["Essen, Germany"]},{"name":"German Cancer Consortium (DKTK), Partner Site Essen\/D\u00fcsseldorf, University Hospital Essen","place":["Essen, Germany"]},{"name":"Center for Molecular Biotechnology, University Hospital Essen","place":["Essen, Germany"]},{"name":"National Center for Tumor Diseases (NCT-West)","place":["Essen, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Carpinteiro","sequence":"additional","affiliation":[{"name":"Institute of Molecular Biology, University Duisburg-Essen","place":["Essen, Germany"]},{"name":"Department of Hematology and Stem Cell Transplantation, University Hospital Essen","place":["Essen, Essen, Germany"]},{"name":"West German Amyloidosis Center, University Hospital Essen","place":["Essen, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2026,6,4]]},"reference":[{"key":"e_1_3_4_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2796.1992.tb00631.x"},{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199709253371306"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-018-0034-3"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2012-12-473066"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2011.38.5724"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-01-0390"},{"key":"e_1_3_4_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/ejh.13681"},{"key":"e_1_3_4_9_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.71.10.4027"},{"key":"e_1_3_4_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(81)90399-8"},{"key":"e_1_3_4_11_1","doi-asserted-by":"publisher","DOI":"10.1107\/s0907444902004183"},{"key":"e_1_3_4_12_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.14.7017"},{"key":"e_1_3_4_13_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-10-743997"},{"key":"e_1_3_4_14_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-01-0114"},{"key":"e_1_3_4_15_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-05-355784"},{"key":"e_1_3_4_16_1","doi-asserted-by":"publisher","DOI":"10.1080\/13506129.2023.2295221"},{"key":"e_1_3_4_17_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M804822200"},{"key":"e_1_3_4_18_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.275.3.1570"},{"key":"e_1_3_4_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbc.2021.100334"},{"key":"e_1_3_4_20_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi991131j"},{"key":"e_1_3_4_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-16953-7"},{"key":"e_1_3_4_22_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.RA118.004142"},{"key":"e_1_3_4_23_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M114.585638"},{"key":"e_1_3_4_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbapap.2016.01.009"},{"key":"e_1_3_4_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/febs.14181"},{"key":"e_1_3_4_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2025.169468"},{"key":"e_1_3_4_27_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-12-618108"},{"key":"e_1_3_4_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-023-04574-y"},{"key":"e_1_3_4_29_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.16.9547"},{"key":"e_1_3_4_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0925-4439(99)00019-8"},{"key":"e_1_3_4_31_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi101351c"},{"key":"e_1_3_4_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2025.168958"},{"key":"e_1_3_4_33_1","doi-asserted-by":"publisher","DOI":"10.1093\/biomethods\/bpae074"},{"key":"e_1_3_4_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.26684"},{"key":"e_1_3_4_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2021.10.017"},{"key":"e_1_3_4_36_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gky066"},{"key":"e_1_3_4_37_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1006583"},{"key":"e_1_3_4_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2016.093"},{"key":"e_1_3_4_39_1","doi-asserted-by":"publisher","DOI":"10.14806\/ej.17.1.200"},{"key":"e_1_3_4_40_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.3364"},{"key":"e_1_3_4_41_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41592-020-01041-y"},{"key":"e_1_3_4_42_1","doi-asserted-by":"publisher","DOI":"10.1080\/10409238.2021.1937926"},{"issue":"2","key":"e_1_3_4_43_1","first-page":"284","article-title":"Binding of serum amyloid P-component (SAP) by amyloid fibrils","volume":"38","author":"Pepys MB","year":"1979","unstructured":"Pepys MB, Dyck RF, de Beer FC, et al. Binding of serum amyloid P-component (SAP) by amyloid fibrils. Clin Exp Immunol. 1979;38(2):284\u2013293.","journal-title":"Clin Exp Immunol"},{"key":"e_1_3_4_44_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0264407"},{"key":"e_1_3_4_45_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-024-07487-w"},{"key":"e_1_3_4_46_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkq399"},{"key":"e_1_3_4_47_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201701761"},{"key":"e_1_3_4_48_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btaf064"},{"key":"e_1_3_4_49_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12859-019-2923-1"},{"key":"e_1_3_4_50_1","first-page":"252","volume-title":"4th International Conference on Computational Physics (PC 92)","author":"Bekker HBH","year":"1993","unstructured":"Bekker HBH, Dijkstra EJ, Achterop S, et al. Gromacs: a parallel computer for molecular dynamics simulations. In: deGroot RA NJ, editor. 4th International Conference on Computational Physics (PC 92). Czech Republic: World Scientific Publishing; 1993. p. 252\u2013256."},{"key":"e_1_3_4_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.softx.2015.06.001"},{"key":"e_1_3_4_52_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.20090"},{"key":"e_1_3_4_53_1","doi-asserted-by":"publisher","DOI":"10.1021\/ct900549r"},{"key":"e_1_3_4_54_1","doi-asserted-by":"publisher","DOI":"10.1002\/prot.22711"},{"key":"e_1_3_4_55_1","doi-asserted-by":"publisher","DOI":"10.1002\/prot.340100306"},{"key":"e_1_3_4_56_1","doi-asserted-by":"publisher","DOI":"10.1111\/febs.16805"},{"key":"e_1_3_4_57_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-3083.1998.00352.x"},{"key":"e_1_3_4_58_1","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1998.9508"},{"key":"e_1_3_4_59_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41375-022-01599-w"},{"key":"e_1_3_4_60_1","doi-asserted-by":"publisher","DOI":"10.1111\/febs.16182"},{"key":"e_1_3_4_61_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-26553-9"},{"key":"e_1_3_4_62_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41375-020-0940-8"},{"key":"e_1_3_4_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2020.10.005"},{"key":"e_1_3_4_64_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1817538116"},{"key":"e_1_3_4_65_1","doi-asserted-by":"publisher","DOI":"10.1080\/13506129.2022.2095618"},{"key":"e_1_3_4_66_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-21126-2"},{"key":"e_1_3_4_67_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-09032-0"},{"key":"e_1_3_4_68_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-09133-w"},{"key":"e_1_3_4_69_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-50686-2"},{"key":"e_1_3_4_70_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.10935"},{"key":"e_1_3_4_71_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1817567116"},{"key":"e_1_3_4_72_1","doi-asserted-by":"publisher","DOI":"10.3390\/hemato2040042"},{"key":"e_1_3_4_73_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-08609-z"}],"container-title":["Amyloid"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/13506129.2026.2679153","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/full-xml\/10.1080\/13506129.2026.2679153","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/13506129.2026.2679153","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T14:34:20Z","timestamp":1790087660000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/13506129.2026.2679153"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,4]]},"references-count":72,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,7,3]]}},"alternative-id":["10.1080\/13506129.2026.2679153"],"URL":"https:\/\/doi.org\/10.1080\/13506129.2026.2679153","relation":{},"ISSN":["1350-6129","1744-2818"],"issn-type":[{"value":"1350-6129","type":"print"},{"value":"1744-2818","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,4]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iamy20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iamy20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2026-02-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-06","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-04","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}