{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T13:01:19Z","timestamp":1774789279046,"version":"3.50.1"},"reference-count":81,"publisher":"Informa UK Limited","issue":"5","funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"crossref","award":["Master&s degree fellowship"],"award-info":[{"award-number":["Master&s degree fellowship"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Opinion on Therapeutic Patents"],"published-print":{"date-parts":[[2019,5,4]]},"DOI":"10.1080\/13543776.2019.1608181","type":"journal-article","created":{"date-parts":[[2019,4,24]],"date-time":"2019-04-24T11:46:49Z","timestamp":1556106409000},"page":"327-337","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":9,"title":["Patent landscape of molecular and cellular targeted therapies for recessive dystrophic epidermolysis bullosa"],"prefix":"10.1080","volume":"29","author":[{"given":"Mariel","family":"Dourado Alcorte","sequence":"first","affiliation":[{"name":"NUCEL - School of Medicine, University of Sao Paulo, S\u00e3o Paulo, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mari Cleide","family":"Sogayar","sequence":"additional","affiliation":[{"name":"NUCEL - School of Medicine, University of Sao Paulo, S\u00e3o Paulo, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcos Angelo","family":"Demasi","sequence":"additional","affiliation":[{"name":"NUCEL - School of Medicine, University of Sao Paulo, S\u00e3o Paulo, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2019,4,24]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.02.004"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2003.05315.x"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.16.6931"},{"key":"CIT0004","volume":"89","author":"Ryyninen J","year":"1992","journal-title":"J Clin Invest"},{"key":"CIT0005","doi-asserted-by":"crossref","first-page":"13706","DOI":"10.1016\/S0021-9258(19)76484-9","volume":"262","author":"LunstrumS GP","year":"1987","journal-title":"J Biol Chem"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1007\/s00441-009-0844-4"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1016\/j.matbio.2014.04.006"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1007\/b103821"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.02780"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.biochem.77.032207.120833"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12365129"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1016\/S0945-053X(98)00007-9"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1002\/humu.21651"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1002\/humu.21551"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1016\/j.det.2009.10.020"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2008.09.035"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.2147\/CCID.S54681"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2016.2473"},{"key":"CIT0019","first-page":"41","volume":"8","author":"Soro L","year":"2015","journal-title":"J Clin Aesthet Dermatol"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1517\/21678707.2013.774274"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1093\/hropen\/hoy024\/5304018"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2016.07.004"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2017.12.003"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2015.158"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.3109\/14653241003587637"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1016\/0142-9612(91)90207-Q"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2018.04.028"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.14974.1"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2008.78"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.12599"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.5582\/irdr.2017.01005"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0910501"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)61897-8"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1089\/wound.2011.0282"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1016\/j.trsl.2015.05.008"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3009540"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.15588"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.1172\/JCI200317193"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1089\/hum.2010.023"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2004.05.016"},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2012.101"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.1038\/gt.2016.57"},{"key":"CIT0054","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkx669"},{"key":"CIT0055","doi-asserted-by":"publisher","DOI":"10.1038\/mtna.2016.3"},{"key":"CIT0056","doi-asserted-by":"publisher","DOI":"10.1089\/104303401753153947"},{"key":"CIT0057","doi-asserted-by":"publisher","DOI":"10.1038\/JID.2015.364"},{"key":"CIT0058","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-62703-761-7_16"},{"key":"CIT0059","doi-asserted-by":"publisher","DOI":"10.1038\/nm1063"},{"key":"CIT0060","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2008.234"},{"key":"CIT0061","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2013.87"},{"key":"CIT0062","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2013.10"},{"key":"CIT0065","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2015.291"},{"key":"CIT0069","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5700435"},{"key":"CIT0070","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-61779-767-5_15"},{"key":"CIT0071","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2016.07.029"},{"key":"CIT0072","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2018.10.011"},{"key":"CIT0078","doi-asserted-by":"publisher","DOI":"10.1089\/oli.2006.16.83"},{"key":"CIT0079","doi-asserted-by":"publisher","DOI":"10.1038\/sj.clpt.6100012"},{"key":"CIT0082","doi-asserted-by":"publisher","DOI":"10.1038\/277146a0"},{"key":"CIT0083","doi-asserted-by":"publisher","DOI":"10.1172\/JCI7866"},{"key":"CIT0084","doi-asserted-by":"publisher","DOI":"10.1038\/nm1197-1280"},{"key":"CIT0085","doi-asserted-by":"publisher","DOI":"10.1002\/ana.1023"},{"key":"CIT0087","doi-asserted-by":"publisher","DOI":"10.1039\/C4MD00081A"},{"key":"CIT0092","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2017.05.011"},{"key":"CIT0093","doi-asserted-by":"publisher","DOI":"10.1038\/nature05756"},{"key":"CIT0096","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-014-0287-4"},{"key":"CIT0097","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(14)70100-6"},{"key":"CIT0098","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)31611-2"},{"key":"CIT0099","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2014.140"},{"key":"CIT0100","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.1001593"},{"key":"CIT0101","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2013.137"},{"key":"CIT0102","doi-asserted-by":"publisher","DOI":"10.1172\/JCI86799"},{"key":"CIT0103","doi-asserted-by":"publisher","DOI":"10.1016\/j.omtn.2018.10.002"},{"key":"CIT0104","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3765"},{"key":"CIT0105","doi-asserted-by":"publisher","DOI":"10.1089\/nat.2013.0454"},{"key":"CIT0106","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1614775114"},{"key":"CIT0107","doi-asserted-by":"publisher","DOI":"10.1016\/j.omtn.2018.01.009"},{"key":"CIT0108","doi-asserted-by":"publisher","DOI":"10.1002\/wrna.1347"},{"key":"CIT0109","doi-asserted-by":"publisher","DOI":"10.1172\/JCI92707"},{"key":"CIT0110","doi-asserted-by":"publisher","DOI":"10.1186\/s10020-018-0024-7"},{"key":"CIT0111","doi-asserted-by":"publisher","DOI":"10.1111\/jwip.12098"}],"container-title":["Expert Opinion on Therapeutic Patents"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/13543776.2019.1608181","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,9,16]],"date-time":"2022-09-16T19:30:02Z","timestamp":1663356602000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/13543776.2019.1608181"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,24]]},"references-count":81,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2019,5,8]]},"published-print":{"date-parts":[[2019,5,4]]}},"alternative-id":["10.1080\/13543776.2019.1608181"],"URL":"https:\/\/doi.org\/10.1080\/13543776.2019.1608181","relation":{},"ISSN":["1354-3776","1744-7674"],"issn-type":[{"value":"1354-3776","type":"print"},{"value":"1744-7674","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,24]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ietp20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ietp20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2019-01-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-04-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-04-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}