{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T04:56:37Z","timestamp":1785214597348,"version":"3.55.0"},"reference-count":43,"publisher":"Informa UK Limited","issue":"11","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Opinion on Therapeutic Patents"],"published-print":{"date-parts":[[2019,11,2]]},"DOI":"10.1080\/13543776.2019.1669562","type":"journal-article","created":{"date-parts":[[2019,9,18]],"date-time":"2019-09-18T01:06:11Z","timestamp":1568768771000},"page":"881-889","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":39,"title":["An update on PTEN modulators \u2013 a patent review"],"prefix":"10.1080","volume":"29","author":[{"given":"Chandra S.","family":"Boosani","sequence":"first","affiliation":[{"name":"Department of Translational Research, Western University of Health Sciences, Pomona, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Palanikumar","family":"Gunasekar","sequence":"additional","affiliation":[{"name":"Department of Clinical & Translational Science, Creighton University School of Medicine, Omaha, NE, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devendra K.","family":"Agrawal","sequence":"additional","affiliation":[{"name":"Department of Translational Research, Western University of Health Sciences, Pomona, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2019,9,23]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.22.13375"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1038\/nrm3330"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1038\/s41580-018-0015-0"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1517\/13543776.2013.768985"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2015.00024"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1038\/ncb1961"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2013.096438"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2006.11.040"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.C100556200"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.20.14.5010-5018.2000"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M009134200"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1126\/science.1161566"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20131780"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-407178-0.00007-7"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1119449109"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4340-10.2010"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2012.01.004"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1038\/nature10594"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2018.02.012"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1007\/s12154-010-0041-7"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1021\/cb600352f"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2004.03.102"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1111\/bph.13727"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.6271-09.2010"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0030012"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2014.02.039"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2013.02.046"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.09-3473"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.3109\/02713680903374208"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1096\/fj.09-152546"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms14328"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms10068"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.20339"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.1038\/nature04703"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-3299-3_15"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.1080\/01616412.2016.1145915"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-015-0280-1"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.3390\/molecules23020285"},{"key":"CIT0045","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-10-4475"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M505143200"},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1016\/S1534-5807(03)00402-7"},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.093773"},{"key":"CIT0055","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-16-0612"}],"container-title":["Expert Opinion on Therapeutic Patents"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/13543776.2019.1669562","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,28]],"date-time":"2019-10-28T12:07:38Z","timestamp":1572264458000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/13543776.2019.1669562"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,23]]},"references-count":43,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2019,10,14]]},"published-print":{"date-parts":[[2019,11,2]]}},"alternative-id":["10.1080\/13543776.2019.1669562"],"URL":"https:\/\/doi.org\/10.1080\/13543776.2019.1669562","relation":{},"ISSN":["1354-3776","1744-7674"],"issn-type":[{"value":"1354-3776","type":"print"},{"value":"1744-7674","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9,23]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ietp20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ietp20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2019-05-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-09-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-09-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}