{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T22:04:19Z","timestamp":1790373859364,"version":"4.1.0"},"reference-count":76,"publisher":"Informa UK Limited","issue":"10","funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81870698"],"award-info":[{"award-number":["81870698"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Changjiang Scholars and Innovative Research Team","award":["IRT13082"],"award-info":[{"award-number":["IRT13082"]}]},{"name":"CAMS Innovation Fund for Medical Sciences","award":["2019-I2M-5-022"],"award-info":[{"award-number":["2019-I2M-5-022"]}]},{"name":"Beijing Municipal Science and Technology Project","award":["Z181100001618002"],"award-info":[{"award-number":["Z181100001618002"]}]},{"name":"Beijing Municipal Administration of Hospitals\u2019 Mission Plan","award":["SML20150203"],"award-info":[{"award-number":["SML20150203"]}]},{"name":"Beijing Municipal Administration of Hospitals\u2019 Dengfeng plan","award":["DFL20190202"],"award-info":[{"award-number":["DFL20190202"]}]},{"name":"Dongcheng District Outstanding Talent Nurturing Program","award":["2022-dchrcpyzz-3"],"award-info":[{"award-number":["2022-dchrcpyzz-3"]}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Opinion on Investigational Drugs"],"published-print":{"date-parts":[[2023,10,3]]},"DOI":"10.1080\/13543784.2023.2273502","type":"journal-article","created":{"date-parts":[[2023,10,19]],"date-time":"2023-10-19T09:50:16Z","timestamp":1697709016000},"page":"909-919","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":11,"title":["Current and emerging biological therapies for Chronic rhinosinusitis with nasal polyps with type 2 inflammation"],"prefix":"10.1080","volume":"32","author":[{"given":"Zeyi","family":"Jin","sequence":"first","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China"},{"name":"Beijing Institute of Otolaryngology, Beijing Laboratory of Allergic Diseases, Beijing Key Laboratory of Nasal Diseases, Key Laboratory of Otolaryngology Head and Neck Surgery, Ministry of Education, Capital Medical University, Beijing, China"},{"name":"Research Unit of Diagnosis and Treatment of Chronic Nasal Diseases, Chinese Academy of Medical Sciences, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing","family":"Yan","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China"},{"name":"Beijing Institute of Otolaryngology, Beijing Laboratory of Allergic Diseases, Beijing Key Laboratory of Nasal Diseases, Key Laboratory of Otolaryngology Head and Neck Surgery, Ministry of Education, Capital Medical University, Beijing, China"},{"name":"Research Unit of Diagnosis and Treatment of Chronic Nasal Diseases, Chinese Academy of Medical Sciences, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luo","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China"},{"name":"Beijing Institute of Otolaryngology, Beijing Laboratory of Allergic Diseases, Beijing Key Laboratory of Nasal Diseases, Key Laboratory of Otolaryngology Head and Neck Surgery, Ministry of Education, Capital Medical University, Beijing, China"},{"name":"Research Unit of Diagnosis and Treatment of Chronic Nasal Diseases, Chinese Academy of Medical Sciences, Beijing, China"},{"name":"Department of Allergy, Beijing TongRen Hospital, Capital Medical University, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengshuo","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, China"},{"name":"Beijing Institute of Otolaryngology, Beijing Laboratory of Allergic Diseases, Beijing Key Laboratory of Nasal Diseases, Key Laboratory of Otolaryngology Head and Neck Surgery, Ministry of Education, Capital Medical University, Beijing, China"},{"name":"Research Unit of Diagnosis and Treatment of Chronic Nasal Diseases, Chinese Academy of Medical Sciences, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2023,10,25]]},"reference":[{"key":"e_1_3_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2016.04.012"},{"key":"e_1_3_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.13042"},{"key":"e_1_3_5_5_1","doi-asserted-by":"publisher","DOI":"10.4193\/Rhin20.401"},{"key":"e_1_3_5_6_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pathol-052016-100401"},{"key":"e_1_3_5_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22741"},{"key":"e_1_3_5_8_1","doi-asserted-by":"publisher","DOI":"10.4193\/Rhin19.184"},{"key":"e_1_3_5_9_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22487"},{"key":"e_1_3_5_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22146"},{"key":"e_1_3_5_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26391"},{"key":"e_1_3_5_12_1","doi-asserted-by":"publisher","DOI":"10.4193\/Rhino15.271"},{"key":"e_1_3_5_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.23035"},{"key":"e_1_3_5_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-023-07856-7"},{"key":"e_1_3_5_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-022-07497-2"},{"key":"e_1_3_5_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2022.02.016"},{"key":"e_1_3_5_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/1744666X.2020.1723417"},{"key":"e_1_3_5_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/14656566.2018.1527904"},{"key":"e_1_3_5_19_1","doi-asserted-by":"publisher","DOI":"10.2174\/1872213X09666150223115303"},{"key":"e_1_3_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)31881-1"},{"key":"e_1_3_5_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2020.05.032"},{"key":"e_1_3_5_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(21)00097-7"},{"key":"e_1_3_5_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.15507"},{"key":"e_1_3_5_24_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2015.19330"},{"key":"e_1_3_5_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2023.102076"},{"key":"e_1_3_5_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2012.07.047"},{"key":"e_1_3_5_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2011.07.056"},{"key":"e_1_3_5_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2017.05.044"},{"key":"e_1_3_5_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/cea.13852"},{"key":"e_1_3_5_30_1","doi-asserted-by":"publisher","DOI":"10.1177\/19458924211009429"},{"key":"e_1_3_5_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2021.08.030"},{"key":"e_1_3_5_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1081-1206(10)63281-4"},{"key":"e_1_3_5_33_1","doi-asserted-by":"publisher","DOI":"10.1093\/intimm\/dxp102"},{"key":"e_1_3_5_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/alr.22994"},{"key":"e_1_3_5_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2019.102286"},{"key":"e_1_3_5_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2015.12.1324"},{"key":"e_1_3_5_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2019.105819"},{"key":"e_1_3_5_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2010.04.004"},{"key":"e_1_3_5_39_1","doi-asserted-by":"publisher","DOI":"10.1080\/1744666X.2021.1847083"},{"key":"e_1_3_5_40_1","doi-asserted-by":"publisher","DOI":"10.4193\/Rhin22.489"},{"key":"e_1_3_5_41_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2222.1999.00542.x"},{"key":"e_1_3_5_42_1","doi-asserted-by":"publisher","DOI":"10.4193\/Rhin19.439"},{"key":"e_1_3_5_43_1","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2014.28.4033"},{"key":"e_1_3_5_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.15002"},{"key":"e_1_3_5_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.14526"},{"key":"e_1_3_5_46_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-022-00735-y"},{"key":"e_1_3_5_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2019.04.101"},{"key":"e_1_3_5_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2013.04.005"},{"key":"e_1_3_5_49_1","doi-asserted-by":"publisher","DOI":"10.1159\/000346929"},{"key":"e_1_3_5_50_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-022-01679-2"},{"key":"e_1_3_5_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(21)00226-5"},{"key":"e_1_3_5_52_1","first-page":"1","article-title":"What place will tezepelumab hold in the treatment paradigm in chronic rhinosinusitis?","volume":"21","author":"Favier V","year":"2023","unstructured":"Favier V, Charriot J, Crampette L, et al. What place will tezepelumab hold in the treatment paradigm in chronic rhinosinusitis? Expert Rev Clin Immunol. 2023 May;21:1\u20135.","journal-title":"Expert Rev Clin Immunol"},{"issue":"3","key":"e_1_3_5_53_1","first-page":"329","article-title":"Reslizumab, a humanized anti-IL-5 mAb for the treatment of eosinophil-mediated inflammatory conditions","volume":"11","author":"Walsh GM","year":"2009","unstructured":"Walsh GM. Reslizumab, a humanized anti-IL-5 mAb for the treatment of eosinophil-mediated inflammatory conditions. Curr Opin Mol Ther. 2009 Jun;11(3):329\u2013336.","journal-title":"Curr Opin Mol Ther"},{"key":"e_1_3_5_54_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-016-0583-2"},{"key":"e_1_3_5_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2006.05.031"},{"key":"e_1_3_5_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2005.09.015"},{"key":"e_1_3_5_57_1","doi-asserted-by":"publisher","DOI":"10.1111\/imr.12552"},{"key":"e_1_3_5_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2009.02.026"},{"key":"e_1_3_5_59_1","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/9155080"},{"key":"e_1_3_5_60_1","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2015.29.4176"},{"key":"e_1_3_5_61_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.12667"},{"key":"e_1_3_5_62_1","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2016-208772"},{"key":"e_1_3_5_63_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-016-4260-6"},{"key":"e_1_3_5_64_1","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24462"},{"key":"#cr-split#-e_1_3_5_65_1.1","unstructured":"ClinicalTrials.Gov [internet]. Bethesda (MD) United States: National Library of Medicine. [updated 2022 May 19"},{"key":"#cr-split#-e_1_3_5_65_1.2","unstructured":"cited 2023 Oct 8]. Available from: https:\/\/clinicaltrials.gov\/study\/NCT02743871"},{"key":"e_1_3_5_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2021.03.044"},{"key":"e_1_3_5_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2022.08.015"},{"key":"e_1_3_5_68_1","doi-asserted-by":"publisher","DOI":"10.1038\/nri3737"},{"key":"e_1_3_5_69_1","doi-asserted-by":"publisher","DOI":"10.1097\/ACI.0000000000000234"},{"key":"e_1_3_5_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2007.10.004"},{"key":"e_1_3_5_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2020.08.001"},{"key":"e_1_3_5_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2021.09.009"},{"key":"e_1_3_5_73_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.14892"},{"key":"e_1_3_5_74_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.15074"},{"key":"e_1_3_5_75_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anai.2019.12.001"},{"key":"e_1_3_5_76_1","doi-asserted-by":"publisher","DOI":"10.1080\/1744666X.2023.2207822"},{"key":"e_1_3_5_77_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(21)00223-X"}],"container-title":["Expert Opinion on Investigational Drugs"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/13543784.2023.2273502","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,24]],"date-time":"2024-09-24T18:30:47Z","timestamp":1727202647000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/13543784.2023.2273502"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,3]]},"references-count":76,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2023,10,3]]}},"alternative-id":["10.1080\/13543784.2023.2273502"],"URL":"https:\/\/doi.org\/10.1080\/13543784.2023.2273502","relation":{},"ISSN":["1354-3784","1744-7658"],"issn-type":[{"value":"1354-3784","type":"print"},{"value":"1744-7658","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,3]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ieid20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ieid20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2023-08-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-10-11","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-10-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}