{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T23:25:17Z","timestamp":1790378717946,"version":"4.1.0"},"reference-count":60,"publisher":"Informa UK Limited","issue":"9","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Opinion on Investigational Drugs"],"published-print":{"date-parts":[[2025,9,2]]},"DOI":"10.1080\/13543784.2025.2546812","type":"journal-article","created":{"date-parts":[[2025,8,9]],"date-time":"2025-08-09T14:44:36Z","timestamp":1754750676000},"page":"655-663","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":6,"title":["Tirzepatide for metabolic dysfunction-associated steatohepatitis: results from phase II clinical trials and perspectives"],"prefix":"10.1080","volume":"34","author":[{"given":"Stefano","family":"Fiorucci","sequence":"first","affiliation":[{"name":"University of Perugia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ginevra","family":"Urbani","sequence":"additional","affiliation":[{"name":"University of Perugia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2025,8,25]]},"reference":[{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.28431"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2021.02.034"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.plipres.2024.101291"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.livres.2025.01.005"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/HEP.0000000000000852"},{"key":"e_1_3_4_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2017.07.027"},{"key":"e_1_3_4_9_1","doi-asserted-by":"publisher","DOI":"10.36469\/jheor.2024.92223"},{"key":"e_1_3_4_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2019.06.021"},{"key":"e_1_3_4_11_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1003100"},{"key":"e_1_3_4_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(22)00165-0"},{"key":"e_1_3_4_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2022.05.003"},{"key":"e_1_3_4_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/ueg2.12525"},{"key":"e_1_3_4_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/lifemeta\/loae029"},{"key":"e_1_3_4_16_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2309000"},{"key":"e_1_3_4_17_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2036205"},{"key":"e_1_3_4_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2024.12.045"},{"key":"e_1_3_4_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(23)00272-8"},{"key":"e_1_3_4_20_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2304286"},{"key":"e_1_3_4_21_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2413258"},{"key":"e_1_3_4_22_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2401755"},{"key":"e_1_3_4_23_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v30.i48.5205"},{"key":"e_1_3_4_24_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27134315"},{"key":"e_1_3_4_25_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12982-024-00200-2"},{"key":"e_1_3_4_26_1","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.140532"},{"key":"e_1_3_4_27_1","doi-asserted-by":"publisher","DOI":"10.3390\/life12010029"},{"key":"e_1_3_4_28_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2116506119"},{"key":"e_1_3_4_29_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21041219"},{"key":"e_1_3_4_30_1","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgaa863"},{"key":"e_1_3_4_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2024.113499"},{"key":"e_1_3_4_32_1","doi-asserted-by":"publisher","DOI":"10.12997\/jla.2023.12.3.213"},{"key":"e_1_3_4_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.14572"},{"key":"e_1_3_4_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.hsr.2022.100032"},{"key":"e_1_3_4_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmet.2018.09.009"},{"key":"e_1_3_4_36_1","doi-asserted-by":"publisher","DOI":"10.5603\/EP.a2022.0014"},{"key":"e_1_3_4_37_1","unstructured":"Collins L Costello RA. Glucagon-Like Peptide-1 Receptor Agonists. 2024 Feb 29. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025."},{"key":"e_1_3_4_38_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2206038"},{"key":"e_1_3_4_39_1","unstructured":"Farzam K Patel P. Tirzepatide. Treasure Island (FL); 2025."},{"key":"e_1_3_4_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)01324-6"},{"key":"e_1_3_4_41_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2107519"},{"key":"e_1_3_4_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)01443-4"},{"key":"e_1_3_4_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)02188-7"},{"key":"e_1_3_4_44_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2022.0078"},{"key":"e_1_3_4_45_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2023.20294"},{"key":"e_1_3_4_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(22)00188-7"},{"key":"e_1_3_4_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(22)00187-5"},{"key":"e_1_3_4_48_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-023-02344-1"},{"key":"e_1_3_4_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2023.09.007"},{"key":"e_1_3_4_50_1","doi-asserted-by":"publisher","DOI":"10.1111\/dom.15269"},{"key":"e_1_3_4_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(23)01200-X"},{"key":"e_1_3_4_52_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-023-02597-w"},{"key":"e_1_3_4_53_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2023.24945"},{"key":"e_1_3_4_54_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2410819"},{"key":"e_1_3_4_55_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2416394"},{"key":"e_1_3_4_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(22)00070-5"},{"key":"e_1_3_4_57_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2401943"},{"key":"e_1_3_4_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(22)00085-7"},{"key":"e_1_3_4_59_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI146353"},{"key":"e_1_3_4_60_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2301972"},{"key":"e_1_3_4_61_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.18042"},{"key":"e_1_3_4_62_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-024-03018-2"}],"container-title":["Expert Opinion on Investigational Drugs"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/13543784.2025.2546812","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T10:33:07Z","timestamp":1763375587000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/13543784.2025.2546812"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,25]]},"references-count":60,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,9,2]]}},"alternative-id":["10.1080\/13543784.2025.2546812"],"URL":"https:\/\/doi.org\/10.1080\/13543784.2025.2546812","relation":{},"ISSN":["1354-3784","1744-7658"],"issn-type":[{"value":"1354-3784","type":"print"},{"value":"1744-7658","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,25]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ieid20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ieid20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2025-04-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}