{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T22:06:02Z","timestamp":1789682762385,"version":"4.0.1"},"reference-count":132,"publisher":"Informa UK Limited","issue":"11","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Opinion on Investigational Drugs"],"published-print":{"date-parts":[[2025,11,2]]},"DOI":"10.1080\/13543784.2025.2586615","type":"journal-article","created":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T07:27:38Z","timestamp":1762414058000},"page":"887-903","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":4,"title":["Sodium channel modulation as a therapeutic strategy for chemotherapy-induced peripheral neurotoxicity"],"prefix":"10.1080","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2223-1574","authenticated-orcid":false,"given":"Sara","family":"Di Girolamo","sequence":"first","affiliation":[{"name":"University of Milano-Bicocca","place":["Monza, Italy"]},{"name":"Milan Center for Neuroscience","place":["Milan, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6936-3852","authenticated-orcid":false,"given":"Giulia","family":"Terribile","sequence":"additional","affiliation":[{"name":"Milan Center for Neuroscience","place":["Milan, Italy"]},{"name":"University of Milano-Bicocca","place":["Monza, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6106-6183","authenticated-orcid":false,"given":"Paola","family":"Alberti","sequence":"additional","affiliation":[{"name":"University of Milano-Bicocca","place":["Monza, Italy"]},{"name":"Fondazione IRCCS","place":["San Gerardo Dei Tintori, Monza, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guido","family":"Cavaletti","sequence":"additional","affiliation":[{"name":"University of Milano-Bicocca","place":["Monza, Italy"]},{"name":"Fondazione IRCCS","place":["San Gerardo Dei Tintori, Monza, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2025,11,12]]},"reference":[{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14246088"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.20.01399"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000012300"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/jns.12097"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mds329"},{"key":"e_1_3_4_8_1","doi-asserted-by":"publisher","DOI":"10.3122\/jabfm.17.5.309"},{"issue":"62","key":"e_1_3_4_9_1","first-page":"3439","article-title":"Nerve excitability assessment in chemotherapy-induced neurotoxicity","volume":"26","author":"Park SB","year":"2012","unstructured":"Park SB, Lin CS, Kiernan MC. Nerve excitability assessment in chemotherapy-induced neurotoxicity. J Vis Exp. 2012 Apr;26(62):3439.","journal-title":"J Vis Exp"},{"key":"e_1_3_4_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2021-328323"},{"key":"e_1_3_4_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdt409"},{"key":"e_1_3_4_12_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2013.54.0914"},{"key":"e_1_3_4_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2019.107905"},{"key":"e_1_3_4_14_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1118058109"},{"key":"e_1_3_4_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2013-305334"},{"key":"e_1_3_4_16_1","doi-asserted-by":"publisher","DOI":"10.4161\/cc.27476"},{"key":"e_1_3_4_17_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2012685118"},{"key":"e_1_3_4_18_1","doi-asserted-by":"publisher","DOI":"10.1053\/sonc.2002.35525"},{"key":"e_1_3_4_19_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1216080109"},{"key":"e_1_3_4_20_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-06-0694"},{"key":"e_1_3_4_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.28234"},{"key":"e_1_3_4_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/jns.12607"},{"key":"e_1_3_4_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00280-012-2006-8"},{"key":"e_1_3_4_24_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00260.2020"},{"key":"e_1_3_4_25_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00052.2017"},{"key":"e_1_3_4_26_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.physiol.61.1.835"},{"key":"e_1_3_4_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2006.01.444"},{"key":"e_1_3_4_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2005.08.002"},{"key":"e_1_3_4_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-41588-3_5"},{"key":"e_1_3_4_30_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-neuro-060909-153234"},{"key":"e_1_3_4_31_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn2023"},{"key":"e_1_3_4_32_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms231710063"},{"key":"e_1_3_4_33_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awp219"},{"key":"e_1_3_4_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn3404"},{"key":"e_1_3_4_35_1","doi-asserted-by":"publisher","DOI":"10.1006\/mcne.2002.1162"},{"key":"e_1_3_4_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2010.08.079"},{"key":"e_1_3_4_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2010.10.002"},{"key":"e_1_3_4_38_1","doi-asserted-by":"publisher","DOI":"10.15252\/embj.201593285"},{"key":"e_1_3_4_39_1","doi-asserted-by":"publisher","DOI":"10.1124\/pr.57.4.4"},{"key":"e_1_3_4_40_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm501981g"},{"key":"e_1_3_4_41_1","doi-asserted-by":"publisher","DOI":"10.1007\/164_2017_48"},{"key":"e_1_3_4_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2010.08.021"},{"key":"e_1_3_4_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2017.04.014"},{"key":"e_1_3_4_44_1","doi-asserted-by":"publisher","DOI":"10.1517\/13543784.16.5.635"},{"key":"e_1_3_4_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2016.08.046"},{"key":"e_1_3_4_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(00)81133-2"},{"key":"e_1_3_4_47_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00024.2004"},{"key":"e_1_3_4_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2022.04.032"},{"key":"e_1_3_4_49_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2014.277582"},{"key":"e_1_3_4_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2020.11.002"},{"key":"e_1_3_4_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2017.11.015"},{"key":"e_1_3_4_52_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0899-17.2017"},{"key":"e_1_3_4_53_1","doi-asserted-by":"publisher","DOI":"10.1177\/1744806917714693"},{"key":"e_1_3_4_54_1","doi-asserted-by":"publisher","DOI":"10.1152\/jn.2001.85.5.2293"},{"key":"e_1_3_4_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurot.2024.e00481"},{"key":"e_1_3_4_56_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awab113"},{"key":"e_1_3_4_57_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awaa208"},{"key":"e_1_3_4_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2023.110944"},{"key":"e_1_3_4_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2015.04.027"},{"key":"e_1_3_4_60_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00210-023-02568-5"},{"key":"e_1_3_4_61_1","doi-asserted-by":"publisher","DOI":"10.1002\/jnr.20873"},{"key":"e_1_3_4_62_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncom.2020.564980"},{"key":"e_1_3_4_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/bs.ctm.2023.09.003"},{"key":"e_1_3_4_64_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25126552"},{"key":"e_1_3_4_65_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0186250"},{"key":"e_1_3_4_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-2999(00)00667-1"},{"key":"e_1_3_4_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2007.07.026"},{"key":"e_1_3_4_68_1","doi-asserted-by":"publisher","DOI":"10.1080\/19336950.2017.1380758"},{"key":"e_1_3_4_69_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1628-04.2004"},{"key":"e_1_3_4_70_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.090034797"},{"key":"e_1_3_4_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2013.05.032"},{"key":"e_1_3_4_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2013.02.027"},{"key":"e_1_3_4_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3959(01)00294-9"},{"key":"e_1_3_4_74_1","doi-asserted-by":"publisher","DOI":"10.1021\/acschemneuro.8b00617"},{"key":"e_1_3_4_75_1","doi-asserted-by":"publisher","DOI":"10.1080\/19336950.2021.2023383"},{"key":"e_1_3_4_76_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.12119"},{"key":"e_1_3_4_77_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature05413"},{"key":"e_1_3_4_78_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2003.047357"},{"key":"e_1_3_4_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ynpai.2021.100082"},{"key":"e_1_3_4_80_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2010.05.019"},{"key":"e_1_3_4_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2007.10.012"},{"key":"e_1_3_4_82_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12264-017-0132-3"},{"key":"e_1_3_4_83_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000000176"},{"key":"e_1_3_4_84_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2217800120"},{"key":"e_1_3_4_85_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.16042"},{"key":"e_1_3_4_86_1","doi-asserted-by":"publisher","DOI":"10.22034\/APJCP.2017.18.11.3157"},{"key":"e_1_3_4_87_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awae071"},{"key":"e_1_3_4_88_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0468-18.2018"},{"key":"e_1_3_4_89_1","doi-asserted-by":"publisher","DOI":"10.2147\/JPR.S207610"},{"key":"e_1_3_4_90_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn3977"},{"key":"e_1_3_4_91_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2018.01510"},{"key":"e_1_3_4_92_1","doi-asserted-by":"publisher","DOI":"10.1080\/19336950.2015.1079674"},{"key":"e_1_3_4_93_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000006083"},{"key":"e_1_3_4_94_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000004272"},{"key":"e_1_3_4_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sbi.2017.02.002"},{"key":"e_1_3_4_96_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2017.08.001"},{"key":"e_1_3_4_97_1","doi-asserted-by":"publisher","DOI":"10.1177\/1744806920901890"},{"key":"e_1_3_4_98_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00424-024-02980-7"},{"key":"e_1_3_4_99_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-024-00523-z"},{"key":"e_1_3_4_100_1","doi-asserted-by":"publisher","DOI":"10.1111\/papr.12705"},{"key":"e_1_3_4_101_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10637-006-9010-y"},{"key":"e_1_3_4_102_1","doi-asserted-by":"publisher","DOI":"10.1080\/13543784.2020.1728254"},{"key":"e_1_3_4_103_1","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000001136"},{"key":"e_1_3_4_104_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2014.08.014"},{"key":"e_1_3_4_105_1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000249344.99671.d4"},{"key":"e_1_3_4_106_1","doi-asserted-by":"publisher","DOI":"10.1517\/14728222.2016.1162295"},{"key":"e_1_3_4_107_1","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000003425"},{"key":"e_1_3_4_108_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-200207020-00019"},{"key":"e_1_3_4_109_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.23482"},{"key":"e_1_3_4_110_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41582-020-00415-2"},{"key":"e_1_3_4_111_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0161450"},{"key":"e_1_3_4_112_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2017.00852"},{"key":"e_1_3_4_113_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(17)49917-0"},{"key":"e_1_3_4_114_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-neuro-070918-050144"},{"key":"e_1_3_4_115_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2016-313804"},{"key":"e_1_3_4_116_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41587-025-02590-3"},{"key":"e_1_3_4_117_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arabjc.2023.105180"},{"key":"e_1_3_4_118_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i5.1298"},{"key":"e_1_3_4_119_1","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-3347"},{"key":"e_1_3_4_120_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-025-02178-w"},{"key":"e_1_3_4_121_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40122-024-00697-0"},{"key":"e_1_3_4_122_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmr.2025.100090"},{"key":"e_1_3_4_123_1","doi-asserted-by":"publisher","DOI":"10.1039\/D5OB00997A"},{"key":"e_1_3_4_124_1","doi-asserted-by":"publisher","DOI":"10.1124\/molpharm.123.000789"},{"key":"e_1_3_4_125_1","doi-asserted-by":"publisher","DOI":"10.1111\/jns.12337"},{"key":"e_1_3_4_126_1","doi-asserted-by":"publisher","DOI":"10.3390\/toxics11020104"},{"key":"e_1_3_4_127_1","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000001227"},{"key":"e_1_3_4_128_1","doi-asserted-by":"publisher","DOI":"10.1111\/bph.13092"},{"key":"e_1_3_4_129_1","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000003445"},{"key":"e_1_3_4_130_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-020-06834-0"},{"key":"e_1_3_4_131_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-016-3031-5"},{"key":"e_1_3_4_132_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2125.2008.03203.x"},{"key":"e_1_3_4_133_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.seizure.2018.01.002"},{"key":"e_1_3_4_134_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eplepsyres.2021.106627"}],"container-title":["Expert Opinion on Investigational Drugs"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/13543784.2025.2586615","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T06:48:41Z","timestamp":1765262921000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/13543784.2025.2586615"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,2]]},"references-count":132,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11,2]]}},"alternative-id":["10.1080\/13543784.2025.2586615"],"URL":"https:\/\/doi.org\/10.1080\/13543784.2025.2586615","relation":{},"ISSN":["1354-3784","1744-7658"],"issn-type":[{"value":"1354-3784","type":"print"},{"value":"1744-7658","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,2]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ieid20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ieid20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2025-04-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}