{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T02:12:04Z","timestamp":1791771124642,"version":"4.3.4"},"reference-count":62,"publisher":"Informa UK Limited","issue":"1","license":[{"start":{"date-parts":[[2026,1,2]],"date-time":"2026-01-02T00:00:00Z","timestamp":1767312000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001184","name":"Cure Cancer Australia","doi-asserted-by":"crossref","award":["GNT1184339"],"award-info":[{"award-number":["GNT1184339"]}],"id":[{"id":"10.13039\/501100001184","id-type":"DOI","asserted-by":"crossref"}]},{"name":"US Department of Defense Congressionally Directed Medical Research Program","award":["W81XWH2110496"],"award-info":[{"award-number":["W81XWH2110496"]}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Opinion on Investigational Drugs"],"published-print":{"date-parts":[[2026,1,2]]},"DOI":"10.1080\/13543784.2026.2616752","type":"journal-article","created":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T08:56:38Z","timestamp":1768553798000},"page":"9-18","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":4,"title":["KIF18A inhibition and its rising role in cancer therapy trials: from bench to bedside"],"prefix":"10.1080","volume":"35","author":[{"given":"Jia Q.","family":"Truong","sequence":"first","affiliation":[{"name":"RMIT University","place":["Melbourne, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tal","family":"Galper","sequence":"additional","affiliation":[{"name":"RMIT University","place":["Melbourne, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica K.","family":"Holien","sequence":"additional","affiliation":[{"name":"RMIT University","place":["Melbourne, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2026,1,22]]},"reference":[{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2024.01.009"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceb.2006.10.002"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gde.2022.101913"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-024-01767-7"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sbi.2020.11.003"},{"key":"e_1_3_4_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2009.09.055"},{"key":"e_1_3_4_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb2994"},{"key":"e_1_3_4_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3310"},{"key":"e_1_3_4_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers17040685"},{"key":"e_1_3_4_12_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0027471"},{"key":"e_1_3_4_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00412-020-00736-7"},{"key":"e_1_3_4_14_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1712169114"},{"key":"e_1_3_4_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2009.12.049"},{"key":"e_1_3_4_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10555-024-10225-3"},{"key":"e_1_3_4_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2011.07.022"},{"key":"e_1_3_4_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2012.02.013"},{"key":"e_1_3_4_19_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200909005"},{"key":"e_1_3_4_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2007.02.036"},{"key":"e_1_3_4_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2007.11.014"},{"key":"e_1_3_4_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-55300-z"},{"key":"e_1_3_4_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/emboj.2010.220"},{"key":"e_1_3_4_24_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.1c02030"},{"key":"e_1_3_4_25_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2021.708900"},{"key":"e_1_3_4_26_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom13020326"},{"key":"e_1_3_4_27_1","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.917352"},{"key":"e_1_3_4_28_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12957-018-1342-5"},{"key":"e_1_3_4_29_1","doi-asserted-by":"publisher","DOI":"10.1002\/iub.2030"},{"key":"e_1_3_4_30_1","doi-asserted-by":"publisher","DOI":"10.21037\/tcr.2019.09.38"},{"key":"e_1_3_4_31_1","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2016.3335"},{"key":"e_1_3_4_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.25916"},{"key":"e_1_3_4_33_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-019-5554-z"},{"key":"e_1_3_4_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/bgq134"},{"key":"e_1_3_4_35_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2022.852049"},{"key":"e_1_3_4_36_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-23-0816"},{"key":"e_1_3_4_37_1","doi-asserted-by":"publisher","DOI":"10.1038\/s43018-023-00699-5"},{"key":"e_1_3_4_38_1","unstructured":"Payton MN. KIF18A inhibitors for treatment of neoplastic diseases. 2021."},{"key":"e_1_3_4_39_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-21447-2"},{"key":"e_1_3_4_40_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-03114-6"},{"key":"e_1_3_4_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2020.09.009"},{"key":"e_1_3_4_42_1","doi-asserted-by":"publisher","DOI":"10.1177\/1947601909358184"},{"key":"e_1_3_4_43_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2414963121"},{"key":"e_1_3_4_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ydbio.2015.03.011"},{"key":"e_1_3_4_45_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200904510"},{"key":"e_1_3_4_46_1","doi-asserted-by":"publisher","DOI":"10.1021\/cb500789h"},{"key":"e_1_3_4_47_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.RA120.013703"},{"key":"e_1_3_4_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2012.10.016"},{"key":"e_1_3_4_49_1","article-title":"Volastra vies for the next big synthetic lethality target","author":"Armstrong M","year":"2024","unstructured":"Armstrong M. Volastra vies for the next big synthetic lethality target. OncologyPipeline. 2024. Available from: https:\/\/www.oncologypipeline.com\/apexonco\/volastra-vies-next-big-synthetic-lethality-target","journal-title":"OncologyPipeline"},{"key":"e_1_3_4_50_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms232213777"},{"key":"e_1_3_4_51_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2025.43.16_suppl.3012"},{"key":"e_1_3_4_52_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23116049"},{"issue":"3","key":"e_1_3_4_53_1","first-page":"155","article-title":"Current management of thrombocytopenia in chronic liver disease","volume":"15","author":"Brown RS","year":"2019","unstructured":"Brown RS. Current management of thrombocytopenia in chronic liver disease. Gastroenterol Hepatol (NY). 2019;15(3):155\u2013157.","journal-title":"Gastroenterol Hepatol (NY)"},{"key":"e_1_3_4_54_1","doi-asserted-by":"publisher","DOI":"10.7861\/clinmedicine.16-6-s104"},{"key":"e_1_3_4_55_1","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.2011.58"},{"key":"e_1_3_4_56_1","doi-asserted-by":"publisher","DOI":"10.1158\/1538-7445.AM2023-4482"},{"key":"e_1_3_4_57_1","doi-asserted-by":"publisher","DOI":"10.1158\/1538-7445.AM2024-664"},{"key":"e_1_3_4_58_1","doi-asserted-by":"publisher","DOI":"10.1158\/1538-7445.AM2024-5946"},{"key":"e_1_3_4_59_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jcim.2c01191"},{"key":"e_1_3_4_60_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.5c00549"},{"key":"e_1_3_4_61_1","doi-asserted-by":"publisher","DOI":"10.1002\/mco2.265"},{"key":"e_1_3_4_62_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-14754-6"},{"key":"e_1_3_4_63_1","unstructured":"P\u00e9rez-Melero C. KSP inhibitors as antimitotic agents. (1873\u20134294 (Electronic))."},{"key":"e_1_3_4_64_1","doi-asserted-by":"publisher","DOI":"10.1021\/jp107255t"}],"container-title":["Expert Opinion on Investigational Drugs"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/13543784.2026.2616752","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T12:49:59Z","timestamp":1770382199000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/13543784.2026.2616752"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,2]]},"references-count":62,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1,2]]}},"alternative-id":["10.1080\/13543784.2026.2616752"],"URL":"https:\/\/doi.org\/10.1080\/13543784.2026.2616752","relation":{},"ISSN":["1354-3784","1744-7658"],"issn-type":[{"value":"1354-3784","type":"print"},{"value":"1744-7658","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,2]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ieid20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ieid20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2025-07-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-11","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-22","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}