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The retention index in the treatment was from 80% in the sixth month, and 65% after one year. The patients were followed\u2010up for 1 year after discharge. For 6 months after discharge 55.4% were still returning for follow\u2010up visits and 20.8% after 1 year, all of them remaining abstinent to opioids. It is concluded that the programme is safe for the patients and shows a better retention index than programmes using oral antagonists, with an improved compliance (negative urine analysis) compared to the latter.<\/jats:p>","DOI":"10.1080\/13556210310001646402","type":"journal-article","created":{"date-parts":[[2004,1,26]],"date-time":"2004-01-26T18:49:13Z","timestamp":1075142953000},"page":"429-438","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":32,"title":["Maintenance treatment with depot opioid antagonists in subcutaneous implants: an alternative in the treatment of opioid dependence"],"prefix":"10.1111","volume":"8","author":[{"given":"JE","family":"Carre\u00f1o","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"CE","family":"Alvarez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"GI","family":"San Narciso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"MT","family":"Bascar\u00e1n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"D\u00edaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Bobes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,6,9]]},"reference":[{"key":"e_1_2_1_2_2","volume-title":"American Psychiatric Association (APA) Psychiatric Self\u2010Assessment and Review [Spanish translation]","year":"2000"},{"key":"e_1_2_1_3_2","unstructured":"AsplerR HardingWMCost\u2010effectiveness analysis of drug abuse treatment: current status and recommendations for future research 1991; In Background papers on drug abuse financing and services approach.Drug Abuse Services Research Series no. 1 DHHS publication (ADM)91\u201317777."},{"key":"e_1_2_1_4_2","unstructured":"Fern\u00e1ndezJJEvoluci\u00f3n hist\u00f3rica de los programmeas de mantenimiento con agonistas opi\u00e1ceos [Historical evolution of maintenance programmes with opiate agonists]1999; pp.19\u201346In:Fern\u00e1ndezJJMarina editors Manual de los tratamientos de mantenimiento con opi\u00e1ceos 1st edn."},{"key":"e_1_2_1_5_2","unstructured":"TorrensMDelMoralETratamiento de los trastornos por adicci\u00f3n a sustancias? 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