{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T21:26:06Z","timestamp":1790285166219,"version":"4.1.0"},"reference-count":75,"publisher":"Informa UK Limited","issue":"3","license":[{"start":{"date-parts":[[2017,5,2]],"date-time":"2017-05-02T00:00:00Z","timestamp":1493683200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["The European Journal of Contraception & Reproductive Health Care"],"published-print":{"date-parts":[[2017,5,4]]},"DOI":"10.1080\/13625187.2017.1317735","type":"journal-article","created":{"date-parts":[[2017,5,2]],"date-time":"2017-05-02T11:32:38Z","timestamp":1493724758000},"page":"183-190","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":40,"title":["Use of cyproterone acetate\/ethinylestradiol in polycystic ovary syndrome: rationale and practical aspects"],"prefix":"10.1080","volume":"22","author":[{"given":"X.","family":"Ruan","sequence":"first","affiliation":[{"name":"Department of Gynecological Endocrinology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University","place":["Beijing, China"]},{"name":"Department of Women\u2019s Health, University Women\u2019s Hospital and Research Centre of Women\u2019s Health, University Clinicum Centre of Tuebingen","place":["Tuebingen, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Kubba","sequence":"additional","affiliation":[{"name":"Community Reproductive and Sexual Healthcare Unit, Guy\u2019s and St. Thomas\u2019 NHS Foundation Trust","place":["London, UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Aguilar","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, University of the Philippines College of Medicine, Center for Advanced Reproductive Medicine, St. Luke\u2019s Medical Center BGC","place":["Manila, Philippines"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.O.","family":"Mueck","sequence":"additional","affiliation":[{"name":"Department of Gynecological Endocrinology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University","place":["Beijing, China"]},{"name":"Department of Women\u2019s Health, University Women\u2019s Hospital and Research Centre of Women\u2019s Health, University Clinicum Centre of Tuebingen","place":["Tuebingen, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2017,5,2]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.4158\/EP15748.DSCPT2"},{"key":"e_1_3_3_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2016.05.003"},{"key":"e_1_3_3_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deh098"},{"key":"e_1_3_3_5_1","unstructured":"National Institutes of Health. Evidence-based methodology workshop on polycystic ovary syndrome December 3\u20135 2012. Executive summary [Internet]. Available from: https:\/\/prevention.nih.gov\/docs\/programs\/pcos\/FinalReport.pdf."},{"key":"e_1_3_3_6_1","doi-asserted-by":"publisher","DOI":"10.2147\/CLEP.S37559"},{"key":"e_1_3_3_7_1","first-page":"111","article-title":"Psychological distress in women with polycystic ovary syndrome from Imam Khomeini Hospital, Tehran","volume":"13","author":"Zafari ZF","year":"2012","unstructured":"Zafari ZF, Jafarabadi M, Naghizadeh MM, et\u00a0al. Psychological distress in women with polycystic ovary syndrome from Imam Khomeini Hospital, Tehran. J Reprod Infertil. 2012;13:111\u2013115.","journal-title":"J Reprod Infertil"},{"key":"e_1_3_3_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmm030"},{"key":"e_1_3_3_9_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2005-0628"},{"key":"e_1_3_3_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2011.09.024"},{"key":"e_1_3_3_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/des042"},{"key":"e_1_3_3_12_1","doi-asserted-by":"publisher","DOI":"10.2147\/IJWH.S11304"},{"key":"e_1_3_3_13_1","first-page":"613","article-title":"Insulin resistance, hypersensitivity of LH, and dual defect hypothesis for the pathogenesis of polycystic ovary syndrome","volume":"84","author":"Poretsky L","year":"1994","unstructured":"Poretsky L, Piper B. Insulin resistance, hypersensitivity of LH, and dual defect hypothesis for the pathogenesis of polycystic ovary syndrome. Obstet Gynecol. 1994;84:613\u2013621.","journal-title":"Obstet Gynecol"},{"key":"e_1_3_3_14_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2002-36706"},{"key":"e_1_3_3_15_1","unstructured":"Royal College of Obstetricians and Gynecologists. Long-term consequences of Polycystic Ovary Syndrome. Green-top Guideline No. 33. November 2014 [Internet]. Available from: https:\/\/www.rcog.org.uk\/en\/guidelines-research-services\/guidelines\/gtg33\/"},{"key":"e_1_3_3_16_1","doi-asserted-by":"publisher","DOI":"10.1210\/er.2011-1034"},{"key":"e_1_3_3_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2007.12.022"},{"key":"e_1_3_3_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmr042"},{"key":"e_1_3_3_19_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2265.2000.00884.x"},{"key":"e_1_3_3_20_1","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.24.6.1050"},{"key":"e_1_3_3_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(07)61345-2"},{"key":"e_1_3_3_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2016.09.042"},{"key":"e_1_3_3_23_1","doi-asserted-by":"publisher","DOI":"10.3109\/09513590.2015.1014783"},{"key":"e_1_3_3_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.12558"},{"key":"e_1_3_3_25_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7827-11-56"},{"key":"e_1_3_3_26_1","doi-asserted-by":"publisher","DOI":"10.3109\/09513590.2014.974535"},{"key":"e_1_3_3_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD001895.pub3"},{"key":"e_1_3_3_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(15)00212-0"},{"key":"e_1_3_3_29_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39289.649410.55"},{"key":"e_1_3_3_30_1","doi-asserted-by":"publisher","DOI":"10.2147\/TCRM.S89737"},{"key":"e_1_3_3_31_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2003-031122"},{"key":"e_1_3_3_32_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2265.2002.01603.x"},{"key":"e_1_3_3_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clindermatol.2015.05.010"},{"key":"e_1_3_3_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.humrep.a136243"},{"key":"e_1_3_3_35_1","doi-asserted-by":"publisher","DOI":"10.1186\/1741-7015-8-41"},{"key":"e_1_3_3_36_1","doi-asserted-by":"publisher","DOI":"10.5152\/jtgga.2014.95776"},{"key":"e_1_3_3_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2012.11.019"},{"key":"e_1_3_3_38_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2013-2350"},{"key":"e_1_3_3_39_1","first-page":"1","article-title":"The polycystic ovary syndrome: a position statement from the European society of endocrinology. Eur","volume":"171","author":"Conway G","year":"2014","unstructured":"Conway G, Dewailly D, Diamanti-Kandarakis E, et\u00a0al. The polycystic ovary syndrome: a position statement from the European society of endocrinology. Eur J Endocrinol. 2014;171:1\u201329.","journal-title":"J Endocrinol"},{"key":"e_1_3_3_40_1","first-page":"527","article-title":"Analysis of serum anti-mullerian hormone levels in the main phenotypes of polycystic ovary syndrome","volume":"37","author":"Lijuan W","year":"2016","unstructured":"Lijuan W, Xiangyan R, Yamei C, et\u00a0al. Analysis of serum anti-mullerian hormone levels in the main phenotypes of polycystic ovary syndrome. J Capital Med Univ. 2016;37:527\u2013531.","journal-title":"J Capital Med Univ"},{"key":"e_1_3_3_41_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2010-0828"},{"key":"e_1_3_3_42_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-992931"},{"key":"e_1_3_3_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2014.05.009"},{"key":"e_1_3_3_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(82)90218-6"},{"key":"e_1_3_3_45_1","first-page":"673","article-title":"Biological effects of various doses of ethinyl estradiol in postmenopausal women","volume":"59","author":"Mandel FP","year":"1982","unstructured":"Mandel FP, Geola FL, Lu JKH, et\u00a0al. Biological effects of various doses of ethinyl estradiol in postmenopausal women. Obstet Gynecol. 1982;59:673\u2013679.","journal-title":"Obstet Gynecol"},{"key":"e_1_3_3_46_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dmi046"},{"key":"e_1_3_3_47_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1211261"},{"key":"e_1_3_3_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2003.09.014"},{"key":"e_1_3_3_49_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD004425.pub6"},{"key":"e_1_3_3_50_1","unstructured":"Bitzer J R\u00f6mer T Da Silva Lopes A The use of CPA\/EE in hyperandrogenic skin symptoms \u2013 a review. 2016."},{"key":"e_1_3_3_51_1","unstructured":"Dianette Summary of Product Characteristics [Internet]. Available from: http:\/\/www.medicines.org.uk\/emc\/medicine\/1814\/SPC\/dianette\/ (last updated 2017)."},{"key":"e_1_3_3_52_1","doi-asserted-by":"publisher","DOI":"10.3109\/09513590009167670"},{"key":"e_1_3_3_53_1","first-page":"548","volume-title":"Gynecol Endocrinol","author":"Wu H","year":"2015","unstructured":"Wu H, Ruan X, Jin J, Mueck AO. Metabolic profile of Diane-35 versus Diane-35 plus metformin in Chinese PCOS women under standardized life-style changes. Gynecol Endocrinol. 2015;31:548--551."},{"key":"e_1_3_3_54_1","first-page":"39S","article-title":"Lipid and lipoprotein changes in relation to oral contraception and hormonal replacement therapy","volume":"49","author":"Burkman RT.","year":"1988","unstructured":"Burkman RT. Lipid and lipoprotein changes in relation to oral contraception and hormonal replacement therapy. Fertil Steril. 1988;49:39S\u201350S.","journal-title":"Fertil Steril"},{"key":"e_1_3_3_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/0010-7824(85)90005-8"},{"key":"e_1_3_3_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(16)32478-4"},{"key":"e_1_3_3_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/0010-7824(86)90065-X"},{"key":"e_1_3_3_58_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199011153232003"},{"key":"e_1_3_3_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(16)32479-6"},{"key":"e_1_3_3_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(90)90578-U"},{"key":"e_1_3_3_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/0010-7824(92)90004-D"},{"key":"e_1_3_3_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)48142-2"},{"key":"e_1_3_3_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(79)92949-0"},{"key":"e_1_3_3_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9681(85)90110-9"},{"key":"e_1_3_3_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9378(88)90199-8"},{"key":"e_1_3_3_66_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2014-3196"},{"key":"e_1_3_3_67_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD010813.pub2"},{"key":"e_1_3_3_68_1","doi-asserted-by":"publisher","DOI":"10.1783\/147118910790291037"},{"key":"e_1_3_3_69_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deg120"},{"key":"e_1_3_3_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2012.08.007"},{"key":"e_1_3_3_71_1","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.120677"},{"key":"e_1_3_3_72_1","doi-asserted-by":"publisher","DOI":"10.1210\/jcem.87.8.8716"},{"key":"e_1_3_3_73_1","volume-title":"Medical eligibility criteria for contraceptive use","author":"World Health Organization.","year":"2015","unstructured":"World Health Organization. Medical eligibility criteria for contraceptive use. 5th ed. Geneva: WHO; 2015.","edition":"5"},{"key":"e_1_3_3_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2012.06.035"},{"key":"e_1_3_3_75_1","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2007-2429"},{"key":"e_1_3_3_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2015.06.030"}],"container-title":["The European Journal of Contraception & Reproductive Health Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/13625187.2017.1317735","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/13625187.2017.1317735","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T13:58:34Z","timestamp":1772719114000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/13625187.2017.1317735"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5,2]]},"references-count":75,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,5,4]]}},"alternative-id":["10.1080\/13625187.2017.1317735"],"URL":"https:\/\/doi.org\/10.1080\/13625187.2017.1317735","relation":{},"ISSN":["1362-5187","1473-0782"],"issn-type":[{"value":"1362-5187","type":"print"},{"value":"1473-0782","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,5,2]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iejc20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iejc20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2016-11-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-04-03","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-04-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-05-02","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}