{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T21:13:34Z","timestamp":1792098814802,"version":"4.4.0"},"reference-count":83,"publisher":"Informa UK Limited","issue":"8","license":[{"start":{"date-parts":[[2019,4,29]],"date-time":"2019-04-29T00:00:00Z","timestamp":1556496000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Economics"],"published-print":{"date-parts":[[2019,8,3]]},"DOI":"10.1080\/13696998.2019.1606002","type":"journal-article","created":{"date-parts":[[2019,4,10]],"date-time":"2019-04-10T16:05:36Z","timestamp":1554912336000},"page":"766-776","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":13,"title":["A cost-effectiveness analysis of denosumab for the prevention of skeletal-related events in patients with multiple myeloma in four European countries: Austria, Belgium, Greece, and Italy"],"prefix":"10.1080","volume":"22","author":[{"given":"Evangelos","family":"Terpos","sequence":"first","affiliation":[{"name":"Department of Clinical Therapeutics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aurelien","family":"Jamotte","sequence":"additional","affiliation":[{"name":"Global Health Economics, Amgen (Europe) GmbH, Rotkreuz, Switzerland;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Christodoulopoulou","sequence":"additional","affiliation":[{"name":"Global Health Economics, Amgen Inc, Thousand Oaks, CA, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Campioni","sequence":"additional","affiliation":[{"name":"Global Health Economics, Amgen (Europe) GmbH, Rotkreuz, Switzerland;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debajyoti","family":"Bhowmik","sequence":"additional","affiliation":[{"name":"Global Health Economics, Amgen Inc, Thousand Oaks, CA, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa","family":"Kennedy","sequence":"additional","affiliation":[{"name":"Epiphany, Los Angeles, CA, USA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang","family":"Willenbacher","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine V, Innsbruck University Hospital & Oncotyrol, Center for Personalized Cancer Medicine, Innsbruck, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2019,4,29]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1155\/2010\/343089"},{"key":"CIT0002","unstructured":"World Health Organization. International Agency for Cancer Research. Global Cancer Observatory. 2018. [cited 2018 Oct 31]. available from: http:\/\/gco.iarc.fr\/"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2012.47.7901"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.4137\/CGM.S16817"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1111\/ecc.12761"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-008-0487-0"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2007.04.022"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2010.62"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-008-0418-0"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1111\/ejh.13044"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.3111\/13696998.2015.1132225"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1080\/13696998.2018.1457531"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1080\/03007995.2018.1532884"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.4081\/hr.2018.7401"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdu103"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2014.117176"},{"key":"CIT0017","unstructured":"European Medicines Agency. XGEVA (denosumab) summary of product characteristics. 2018. [cited 2018 Nov 29]. Available from: https:\/\/www.ema.europa.eu\/documents\/product-information\/xgeva-epar-product-information_en.pdf"},{"key":"CIT0018","unstructured":"European Medicines Agency. Zometa (zoledronic acid) summary of product characteristics. 2018. [cited 2018 Nov 29]. Available from: https:\/\/www.ema.europa.eu\/documents\/product-information\/zometa-epar-product-information_en.pdf"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdx096"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(18)30072-X"},{"key":"CIT0021","first-page":"CD003188","volume":"12","author":"Mhaskar R","year":"2017","journal-title":"Cochrane Database Syst Rev"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2010.11.020"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.1075"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2015.65.0044"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2017.76.6402"},{"key":"CIT0026","unstructured":"National Comprehensive Cancer Network (NCCN). NCCN guidelines. Multiple myeloma (version 2, 2019). 2018. [cited 2018 Nov 30]. Available from: https:\/\/www.nccn.org\/professionals\/physician_gls\/PDF\/myeloma.pdf"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2012.08.002"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-18-1537"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-018-2941-0"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1016\/j.jval.2016.12.005"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1080\/13696998.2018.1445634"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.3111\/13696998.2013.779921"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1080\/13696998.2017.1328423"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.23164"},{"key":"CIT0035","unstructured":"Statistik Austria. Life tables. 2017. [cited 2018 Nov 20]. Available from: http:\/\/www.statistik.at\/web_de\/statistiken\/menschen_und_gesellschaft\/bevoelkerung\/sterbetafeln\/index.html"},{"key":"CIT0036","unstructured":"European Health and Life Expectancy Information System. Life tables \u2013 Greece. 2015. [cited 2018 Nov 20]. Available from: http:\/\/www.eurohex.eu"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.17265\/2159-5313\/2016.09.003"},{"key":"CIT0038","unstructured":"Statistics Belgium (STATBEL). Life expectancy and life tables. 2017. [cited 2018 Nov 30]. Available from: https:\/\/statbel.fgov.be\/en\/themes\/population\/life-expectancy-and-life-tables#panel-12"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1007\/s10198-012-0443-2"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.3111\/13696998.2012.675380"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.2147\/PPA.S44947"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2004.01.019"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.1007\/s10354-006-0360-z"},{"key":"CIT0044","volume-title":"Belgian guidelines for economic evaluations and budget impact analyses","author":"Cleemput I","year":"2012","edition":"2"},{"key":"CIT0045","unstructured":"National Institute for Health and Care Excellence (United Kingdom). Processing and methods guidance [PMG9]. Guide to the methods of technology appraisal. 2013. [cited 2018 Nov 20]. Available from: https:\/\/www.nice.org.uk\/process\/pmg9\/resources\/guide-to-the-methods-of-technology-appraisal-2013-pdf-2007975843781"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.1177\/009286150103500122"},{"key":"CIT0047","unstructured":"Warenverzeichnis (Austria). Official list price of drugs. 2018. [cited 2018 Nov 20]. Available from: https:\/\/warenverzeichnis.apoverlag.at\/"},{"key":"CIT0048","unstructured":"National Institute for Health and Disability Insurance \u2013 INAMI\u2013RIZIV (Belgium). Reimbursed pharmaceutical drugs: list and reference files. 2018. [cited 2018 Nov 20]. Available from: https:\/\/www.inami.fgov.be\/fr\/themes\/cout-remboursement\/par-mutualite\/medicament-produits-sante\/remboursement\/specialites\/Pages\/specialites-pharmaceutiques-remboursables-listes-fichiers-reference.aspx#.WRA3UlWLS70"},{"key":"CIT0049","unstructured":"Ministry of Health (Greece). Corrected price list for medicines for human use, November 2017. 2018. [cited 2018 Nov 20]. Available from: http:\/\/www.moh.gov.gr\/articles\/times-farmakwn\/deltia-timwn\/5313-laquo-diorthwtiko-deltio-timwn-farmakwn-anthrwpinhs-xrhshs-noembrioy-2017-raquo"},{"key":"CIT0050","unstructured":"Ministry of Health (Greece). Decree 1702\/B\/01.08. 2011. [cited 2018 Nov 20]. Available from: http:\/\/www.moh.gov.gr\/articles\/ken-eswteriko\/710-ypoyrgikes-apofaseis-egkyklioi-g-g?fdl=2431"},{"key":"CIT0051","unstructured":"Codifa (Italy). 2018. [cited 2018 Nov 28]. Available from: https:\/\/www.codifa.it\/"},{"key":"CIT0052","unstructured":"Official Gazette of the Italian Republic. General series. Ordinary supplement. 2013. [cited 2018 Nov 30]. Available from: http:\/\/www.gazzettaufficiale.it\/"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.3111\/13696998.2016.1150852"},{"key":"CIT0054","doi-asserted-by":"publisher","DOI":"10.3111\/13696998.2013.774279"},{"key":"CIT0055","unstructured":"Statistics Belgium (STATBEL). Consumer price index and health index. 2017. [cited 2018 Nov 20]. Available from: https:\/\/statbel.fgov.be\/en\/open-data\/consumer-price-index-and-health-index"},{"key":"CIT0056","unstructured":"European Central Bank. Euro reference exchange rate: Swiss Franc (CHF). Average: 1 January 2017 to 31 December 2017. [cited 2018 Nov 20]. Available from: https:\/\/www.ecb.europa.eu\/stats\/policy_and_exchange_rates\/euro_reference_exchange_rates\/html\/eurofxref-graph-chf.en.html"},{"key":"CIT0057","unstructured":"European Commission. Eurostat. Gross domestic product at market prices. 2017. [cited 2018 Nov 2]. Available from: https:\/\/ec.europa.eu\/eurostat\/tgm\/table.do?tab=table&init=1&language=en&pcode=tec00001&plugin=0&tableSelection=1"},{"key":"CIT0058","unstructured":"European Network for Health Technology Assessment. Methods for health economic evaluations \u2013 a guideline based on current practices in Europe. 2015. [cited 2018 Nov 5]. Available from: https:\/\/www.eunethta.eu\/wp-content\/uploads\/2018\/03\/Methods_for_health_economic_evaluations.pdf"},{"key":"CIT0059","doi-asserted-by":"publisher","DOI":"10.2471\/BLT.14.138206"},{"key":"CIT0060","doi-asserted-by":"publisher","DOI":"10.1186\/1478-7547-1-8"},{"key":"CIT0061","doi-asserted-by":"publisher","DOI":"10.1093\/heapol\/czw096"},{"key":"CIT0062","unstructured":"Orphanet. Orphanet report series: rare diseases collection. Rare disease registries in Europe. 2018. [cited 2018 Nov 8]. Available from: https:\/\/www.orpha.net\/orphacom\/cahiers\/docs\/GB\/Registries.pdf"},{"key":"CIT0063","doi-asserted-by":"publisher","DOI":"10.1016\/j.healthpol.2017.03.009"},{"key":"CIT0064","unstructured":"Institute for Clinical or Economic Review (ICER). Assessing the effectiveness and value of drugs for rare conditions: a technical brief for the ICER orphan drug assessment & pricing summit. 2017. [cited 2018 Nov 5]. Available from: https:\/\/icer-review.org\/wp-content\/uploads\/2017\/02\/ICER_Assessing-the-Value-of-Drugs-for-Rare-Conditions_051017.pdf"},{"key":"CIT0065","unstructured":"National Institute for Health and Care Excellence (United Kingdom). NICE and NHS England consultation on changes to the arrangements for evaluating and funding drugs and other health technologies assessed through NICE\u2019s technology appraisal and highly specialised technologies programmes. 2017. [cited 2018 Nov 5]. Available from: https:\/\/www.nice.org.uk\/Media\/Default\/About\/what-we-do\/NICE-guidance\/NICE-technology-appraisals\/board-paper-TA-HST-consultation-mar-17-HST-only.pdf"},{"key":"CIT0066","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.14193"},{"key":"CIT0067","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-018-4133-1"},{"key":"CIT0068","doi-asserted-by":"publisher","DOI":"10.1111\/ecc.12490"},{"key":"CIT0069","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2017.00384"},{"key":"CIT0070","unstructured":"European Commission. Mapping of HTAs methodologies in EU and Norway. 2017. [cited 2018 Nov 5]. Available from: https:\/\/ec.europa.eu\/health\/sites\/health\/files\/technology_assessment\/docs\/2018_mapping_methodologies_en.pdf"},{"key":"CIT0071","first-page":"25","volume":"4","author":"Yfantopoulos J","year":"2013","journal-title":"Forum Clin Oncol"},{"key":"CIT0072","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-013-1790-y"},{"key":"CIT0073","doi-asserted-by":"publisher","DOI":"10.1586\/14737167.2016.1123624"},{"key":"CIT0074","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2017.73.7437"},{"key":"CIT0075","doi-asserted-by":"publisher","DOI":"10.3111\/13696998.2012.719054"},{"key":"CIT0076","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2012.04.008"},{"key":"CIT0077","doi-asserted-by":"publisher","DOI":"10.3310\/hta17290"},{"key":"CIT0078","doi-asserted-by":"publisher","DOI":"10.1016\/j.clbc.2012.04.001"},{"key":"CIT0079","doi-asserted-by":"publisher","DOI":"10.18553\/jmcp.2011.17.8.621"},{"key":"CIT0080","doi-asserted-by":"publisher","DOI":"10.1586\/erp.12.31"},{"key":"CIT0081","doi-asserted-by":"publisher","DOI":"10.1136\/ejhpharm-2012-000235"},{"key":"CIT0082","doi-asserted-by":"publisher","DOI":"10.1080\/17474086.2018.1437345"},{"key":"CIT0083","doi-asserted-by":"publisher","DOI":"10.1016\/j.jval.2015.02.001"}],"container-title":["Journal of Medical Economics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/tandfonline.com\/doi\/pdf\/10.1080\/13696998.2019.1606002","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/13696998.2019.1606002","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,14]],"date-time":"2022-10-14T07:26:39Z","timestamp":1665732399000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/13696998.2019.1606002"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,29]]},"references-count":83,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2019,8,3]]}},"alternative-id":["10.1080\/13696998.2019.1606002"],"URL":"https:\/\/doi.org\/10.1080\/13696998.2019.1606002","relation":{},"ISSN":["1369-6998","1941-837X"],"issn-type":[{"value":"1369-6998","type":"print"},{"value":"1941-837X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,29]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ijme20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ijme20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2019-02-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-03-27","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-04-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-04-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}