{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:57:12Z","timestamp":1792785432075,"version":"4.5.0"},"reference-count":13,"publisher":"Informa UK Limited","issue":"1","license":[{"start":{"date-parts":[[2024,3,18]],"date-time":"2024-03-18T00:00:00Z","timestamp":1710720000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"Bristol Myers Squibb"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Economics"],"published-print":{"date-parts":[[2024,12,31]]},"DOI":"10.1080\/13696998.2024.2323903","type":"journal-article","created":{"date-parts":[[2024,2,29]],"date-time":"2024-02-29T03:07:07Z","timestamp":1709176027000},"page":"463-472","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":10,"title":["Post-approval indications and clinical trials for cardiovascular drugs: some implications of the US Inflation Reduction Act"],"prefix":"10.1080","volume":"27","author":[{"given":"Henry","family":"Grabowski","sequence":"first","affiliation":[{"name":"Department of Economics (Emeritus), Duke University","place":["Durham, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Genia","family":"Long","sequence":"additional","affiliation":[{"name":"Analysis Group, Inc","place":["Boston, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2024,3,18]]},"reference":[{"key":"e_1_3_5_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000001123"},{"key":"e_1_3_5_3_1","unstructured":"Ward C Ewald E Koenig K et\u00a0al. Prevalence and health care expenditures among Medicare beneficiaries aged 65 years and over with heart conditions. Medicare Current Beneficiary Survey data highlight. 2017. https:\/\/www.cms.gov\/Research-Statistics-Data-and-Systems\/Research\/MCBS\/Downloads\/HeartConditions_DataBrief_2017.pdf"},{"key":"e_1_3_5_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41581-019-0244-2"},{"key":"e_1_3_5_5_1","unstructured":"Avalere Health. Updated reconciliation package changes drugs eligible for negotiation. 2022. https:\/\/avalere.com\/insights\/updated-reconciliation-package-changes-drugs-eligible-for-negotiation"},{"key":"e_1_3_5_6_1","unstructured":"Congressional Budget Office. How CBO Estimated the Budgetary Impact of Key Prescription Drug Provisions in the 2022 Reconciliation Act. 2023. https:\/\/www.cbo.gov\/system\/files\/2023-02\/58850-IRA-Drug-Provs.pdf"},{"key":"e_1_3_5_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/13696998.2021.1952795"},{"key":"e_1_3_5_8_1","doi-asserted-by":"publisher","DOI":"10.1377\/hlthaff.2024.00202"},{"key":"e_1_3_5_9_1","unstructured":"ClinicalTrials.gov. Protocol registration data element definitions for interventional and observational studies. 2024. https:\/\/clinicaltrials.gov\/policy\/protocol-definitions"},{"key":"e_1_3_5_10_1","unstructured":"Berger B et\u00a0al. Regulatory approval and expanded market size. NBER Working Paper No. 28889 2021. https:\/\/www.nber.org\/system\/files\/working_papers\/w28889\/w28889.pdf"},{"key":"e_1_3_5_11_1","unstructured":"Longo N. Partnership for Health Analytic Research. Implications of the Inflation Reduction Act price setting provisions on post-approval indications for small molecule medicines 2023. https:\/\/www.pharllc.com\/wp-content\/uploads\/2023\/05\/Implications-of-the-IRA-on-Post-Approval-Small-Molecules-2006-2012_Final.pdf."},{"key":"e_1_3_5_12_1","unstructured":"Long N. New government price setting policy threatens post-approval research. (Blog post) November 10 2022. https:\/\/catalyst.phrma.org\/new-government-price-setting-policy-threatens-post-approval-research"},{"key":"e_1_3_5_13_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2307563"},{"key":"e_1_3_5_14_1","unstructured":"Quantitative Life Sciences. Clinical development success rates and contributing factors 2011-2020. 2021. https:\/\/www.bio.org\/clinical-development-success-rates-and-contributing-factors-2011-2020"}],"container-title":["Journal of Medical Economics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/13696998.2024.2323903","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T06:46:05Z","timestamp":1772779565000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/13696998.2024.2323903"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,18]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,12,31]]}},"alternative-id":["10.1080\/13696998.2024.2323903"],"URL":"https:\/\/doi.org\/10.1080\/13696998.2024.2323903","relation":{},"ISSN":["1369-6998","1941-837X"],"issn-type":[{"value":"1369-6998","type":"print"},{"value":"1941-837X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,18]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ijme20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ijme20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2024-02-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-02-22","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-02-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-18","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}