{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T13:16:52Z","timestamp":1791379012963,"version":"4.3.2"},"reference-count":38,"publisher":"Informa UK Limited","issue":"1","license":[{"start":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T00:00:00Z","timestamp":1770076800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Journal of Medical Economics"],"published-print":{"date-parts":[[2026,12,31]]},"DOI":"10.1080\/13696998.2026.2618930","type":"journal-article","created":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T16:16:26Z","timestamp":1770135386000},"page":"308-318","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":1,"title":["Economic burden of non-transfusion-dependent thalassemia in the United States"],"prefix":"10.1080","volume":"29","author":[{"given":"Arielle L.","family":"Langer","sequence":"first","affiliation":[{"name":"Division of Hematology, Brigham and Women\u2019s Hospital, Harvard Medical School","place":["Boston, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amey","family":"Rane","sequence":"additional","affiliation":[{"name":"Agios Pharmaceuticals, Inc.","place":["Cambridge, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keely S.","family":"Gilroy","sequence":"additional","affiliation":[{"name":"Agios Pharmaceuticals, Inc.","place":["Cambridge, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Zhao","sequence":"additional","affiliation":[{"name":"Agios Pharmaceuticals, Inc.","place":["Cambridge, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise","family":"Lombard","sequence":"additional","affiliation":[{"name":"Agios Pharmaceuticals, Inc.","place":["Cambridge, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolyn R.","family":"Lew","sequence":"additional","affiliation":[{"name":"Merative","place":[", Ann Arbor, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sujit","family":"Sheth","sequence":"additional","affiliation":[{"name":"Division of Pediatric Hematology and Oncology, Department of Pediatrics, Weill Cornell Medical College","place":["New York, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2026,2,3]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.1179\/102453312X13336169155295"},{"key":"e_1_3_3_3_1","volume-title":"Guidelines for the management of transfusion dependent thalassaemia (TDT)","author":"Cappellini MD","year":"2021","unstructured":"Cappellini MD, Farmakis D, Porter J, et al. Guidelines for the management of transfusion dependent thalassaemia (TDT). 4th ed. Nicosia (Cyprus): Thalassaemia International Federation; 2021.","edition":"4"},{"key":"e_1_3_3_4_1","volume-title":"Guidelines for the management of non-transfusion-dependent \u03b2-thalasemia","author":"Taher A","year":"2023","unstructured":"Taher A, Musallam KM, Cappellini MD. Guidelines for the management of non-transfusion-dependent \u03b2-thalasemia. 3rd ed. Nicosia (Cyprus): Thalassaemia International Federation; 2023.","edition":"3"},{"key":"e_1_3_3_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra2021838"},{"issue":"4","key":"e_1_3_3_6_1","first-page":"339","article-title":"Alpha and beta thalassemia","volume":"80","author":"Muncie HL","year":"2009","unstructured":"Muncie HL, Campbell J. Alpha and beta thalassemia. Am Fam Physician. 2009;80(4):339\u2013344.","journal-title":"Am Fam Physician"},{"key":"e_1_3_3_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.blre.2023.101165"},{"key":"e_1_3_3_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.26056"},{"key":"e_1_3_3_9_1","volume-title":"Thalassaemia International Federation","author":"Amid A","year":"2023","unstructured":"Amid A, Lal A, Coates TD, et al. Guidelines for the management of \u03b1-thalassaemia. Nicosia (Cyprus): Thalassaemia International Federation. 2023."},{"key":"e_1_3_3_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/ejh.13512"},{"key":"e_1_3_3_11_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.27006"},{"key":"e_1_3_3_12_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1404415"},{"key":"e_1_3_3_13_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/727905"},{"key":"e_1_3_3_14_1","doi-asserted-by":"publisher","DOI":"10.3109\/07853890.2015.1091942"},{"key":"e_1_3_3_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/HS9.0000000000000806"},{"key":"e_1_3_3_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.25584"},{"key":"e_1_3_3_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.blre.2018.02.001"},{"key":"e_1_3_3_18_1","unstructured":"Reblozyl. Summary of product characteristics. Available from: https:\/\/www.ema.europa.eu\/en\/documents\/product-information\/reblozyl-epar-product-information_en.pdf."},{"key":"e_1_3_3_19_1","unstructured":"Reblozyl. Highlights of prescribing information. 2020. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2020\/761136orig2lbl.pdf."},{"key":"e_1_3_3_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/hs9.0000000000000732"},{"key":"e_1_3_3_21_1","doi-asserted-by":"publisher","DOI":"10.3390\/medicina58101496"},{"key":"e_1_3_3_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-022-07663-6"},{"key":"e_1_3_3_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/jha2.282"},{"key":"e_1_3_3_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/trf.16636"},{"key":"e_1_3_3_25_1","doi-asserted-by":"publisher","DOI":"10.1080\/13696998.2023.2235928"},{"key":"e_1_3_3_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1705287"},{"key":"e_1_3_3_27_1","doi-asserted-by":"publisher","DOI":"10.1177\/10105395231197909"},{"key":"e_1_3_3_28_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-020-02160-3"},{"key":"e_1_3_3_29_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13023-021-01791-8"},{"key":"e_1_3_3_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-020-03958-y"},{"key":"e_1_3_3_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-020-04370-2"},{"key":"e_1_3_3_32_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-021-04456-5"},{"key":"e_1_3_3_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcmd.2015.05.011"},{"key":"e_1_3_3_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.26428"},{"key":"e_1_3_3_35_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V130.Suppl_1.2094"},{"key":"e_1_3_3_36_1","unstructured":"U.S. Bureau of Labor Statistics. Consumer price index for all urban consumers CPI inflation calculator. 2024. Available from: https:\/\/www.bls.gov\/data\/inflation_calculator.htm."},{"key":"e_1_3_3_37_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V130.Suppl_1.3368"},{"key":"e_1_3_3_38_1","doi-asserted-by":"publisher","DOI":"10.1111\/nyas.15100"},{"key":"e_1_3_3_39_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2022-167265"}],"container-title":["Journal of Medical Economics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/13696998.2026.2618930","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T16:16:28Z","timestamp":1770135388000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/13696998.2026.2618930"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,3]]},"references-count":38,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,12,31]]}},"alternative-id":["10.1080\/13696998.2026.2618930"],"URL":"https:\/\/doi.org\/10.1080\/13696998.2026.2618930","relation":{},"ISSN":["1369-6998","1941-837X"],"issn-type":[{"value":"1369-6998","type":"print"},{"value":"1941-837X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,3]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ijme20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ijme20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2025-10-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-22","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}