{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T05:26:16Z","timestamp":1784265976010,"version":"3.55.0"},"reference-count":28,"publisher":"Informa UK Limited","issue":"1","license":[{"start":{"date-parts":[[2016,12,9]],"date-time":"2016-12-09T00:00:00Z","timestamp":1481241600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"This study was supported by Project of Traditional Chinese Medicine Administration of Shandong Province, China","award":["No.: 2013-231"],"award-info":[{"award-number":["No.: 2013-231"]}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Pharmaceutical Biology"],"published-print":{"date-parts":[[2017,1]]},"DOI":"10.1080\/13880209.2016.1247879","type":"journal-article","created":{"date-parts":[[2016,12,19]],"date-time":"2016-12-19T02:17:48Z","timestamp":1482113868000},"page":"450-455","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":43,"title":["Effects and mechanisms of pirfenidone, prednisone and acetylcysteine on pulmonary fibrosis in rat idiopathic pulmonary fibrosis models"],"prefix":"10.1080","volume":"55","author":[{"given":"Wencheng","family":"Yu","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine, The Affiliated Hospital of Qingdao University, Qingdao, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Laiwu City People\u2019s Hospital, Laiwu, China;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoxia","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Unit, The Affiliated Hospital of Qingdao University, Qingdao, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2016,12,9]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI114808"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.taap.2007.11.012"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.23791"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.1999.276.2.L311"},{"key":"e_1_3_2_6_1","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/S0022-3565(24)35110-9","article-title":"Effects of pirfenidone on transforming growth factor-beta gene expression at the transcriptional level in bleomycin hamster model of lung fibrosis","volume":"291","author":"Iyer S","year":"1999","unstructured":"Iyer S, Gurujeyalakshmi G, Giri S. 1999. Effects of pirfenidone on transforming growth factor-beta gene expression at the transcriptional level in bleomycin hamster model of lung fibrosis. J Pharmacol Exp Ther. 291:367\u2013373.","journal-title":"J Pharmacol Exp Ther"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.00108s4751"},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.1006\/meth.2001.1262"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.124.4_MeetingAbstracts.116S-b"},{"key":"e_1_3_2_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-2999(02)01758-2"},{"key":"e_1_3_2_11_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.10.5419"},{"key":"e_1_3_2_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2008.06.046"},{"key":"e_1_3_2_13_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.163.6.2006064"},{"key":"e_1_3_2_14_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.0000081743.35125.05"},{"key":"e_1_3_2_15_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0034-1393036"},{"key":"e_1_3_2_16_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1113354"},{"key":"e_1_3_2_17_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M008340200"},{"key":"e_1_3_2_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(92)90143-Z"},{"key":"e_1_3_2_19_1","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2011-0349OC"},{"key":"e_1_3_2_20_1","unstructured":"Sun R. 2003. Translocation of caveolin-1 induced by shearing stress in endothelial cells. Awarded Papers of the 7th Beijing youth science and technology paper award competition."},{"key":"e_1_3_2_21_1","first-page":"893","article-title":"Bleomycin-induced interstitial pulmonary disease in the nude, athymic mouse 1, 2","volume":"120","author":"Szapiel SV","year":"1979","unstructured":"Szapiel SV, Elson NA, Fulmer JD, Hunninghake GW, Crystal RG. 1979. Bleomycin-induced interstitial pulmonary disease in the nude, athymic mouse 1, 2. Am Rev Respir Dis. 120:893\u2013899.","journal-title":"Am Rev Respir Dis"},{"key":"e_1_3_2_22_1","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00005209"},{"key":"e_1_3_2_23_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.med.55.091902.103810"},{"key":"e_1_3_2_24_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2009.117580"},{"key":"e_1_3_2_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2008.01.036"},{"key":"e_1_3_2_26_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20061536"},{"key":"e_1_3_2_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)62351-6"},{"key":"e_1_3_2_28_1","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2010.091117"},{"key":"e_1_3_2_29_1","doi-asserted-by":"publisher","DOI":"10.1006\/excr.1998.4379"}],"container-title":["Pharmaceutical Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/tandfonline.com\/doi\/pdf\/10.1080\/13880209.2016.1247879","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/13880209.2016.1247879","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T18:34:20Z","timestamp":1749839660000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/13880209.2016.1247879"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12,9]]},"references-count":28,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1]]}},"alternative-id":["10.1080\/13880209.2016.1247879"],"URL":"https:\/\/doi.org\/10.1080\/13880209.2016.1247879","relation":{},"ISSN":["1388-0209","1744-5116"],"issn-type":[{"value":"1388-0209","type":"print"},{"value":"1744-5116","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,12,9]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iphb20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iphb20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2016-03-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-10-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-12-09","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}