{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T19:48:00Z","timestamp":1793908080162,"version":"4.8.0"},"reference-count":25,"publisher":"Informa UK Limited","issue":"1","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Pharmaceutical Biology"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1080\/13880209.2021.1979595","type":"journal-article","created":{"date-parts":[[2021,9,28]],"date-time":"2021-09-28T21:23:35Z","timestamp":1632864215000},"page":"1324-1331","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":44,"title":["Isovitexin alleviates acute gouty arthritis in rats by inhibiting inflammation via the TLR4\/MyD88\/NF-\u03baB pathway"],"prefix":"10.1080","volume":"59","author":[{"given":"Xiujiang","family":"Sun","sequence":"first","affiliation":[{"name":"Department of Orthopedics, Yantaishan Hospital, Yantai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Traumatology, Dezhou Hospital of Traditional Chinese Medicine, Dezhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyi","family":"Qu","sequence":"additional","affiliation":[{"name":"Clinical Teaching and Research Section, Yantai Nursing School, Yantai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenguang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Joint Surgery, the Second Hospital of Shandong University, Jinan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2021,9,28]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/35021228"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.3892\/br.2014.224"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19092729"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.2147\/JIR.S299557"},{"issue":"2","key":"e_1_3_2_6_1","first-page":"CD005521","article-title":"Systemic corticosteroids for acute gout","volume":"2","author":"Janssens HJ","year":"2008","unstructured":"Janssens HJ, Lucassen PL, Van de Laar FA, Janssen M, Van de Lisdonk EH. 2008. Systemic corticosteroids for acute gout. Cochrane Database Syst Rev. 2(2):CD005521.","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.1863"},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.02650"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.174.8.5016"},{"key":"e_1_3_2_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.21238"},{"key":"e_1_3_2_11_1","doi-asserted-by":"publisher","DOI":"10.7150\/ijbs.13188"},{"key":"e_1_3_2_12_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules24173161"},{"key":"e_1_3_2_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/icb.2009.89"},{"key":"e_1_3_2_14_1","doi-asserted-by":"publisher","DOI":"10.1021\/np070351s"},{"key":"e_1_3_2_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00281-013-0361-0"},{"key":"e_1_3_2_16_1","doi-asserted-by":"publisher","DOI":"10.3109\/14397595.2013.874732"},{"key":"e_1_3_2_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-013-2856-3"},{"key":"e_1_3_2_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2019.104351"},{"key":"e_1_3_2_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2009.10.005"},{"key":"e_1_3_2_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature01991"},{"key":"e_1_3_2_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/emermed-2017-207129.1"},{"key":"e_1_3_2_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/ar2143"},{"key":"e_1_3_2_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-015-0554-0"},{"key":"e_1_3_2_24_1","doi-asserted-by":"publisher","DOI":"10.1248\/bpb.b16-00756"},{"key":"e_1_3_2_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2016.12.012"},{"key":"e_1_3_2_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpba.2014.08.033"}],"container-title":["Pharmaceutical Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/13880209.2021.1979595","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,25]],"date-time":"2024-03-25T16:17:44Z","timestamp":1711383464000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/13880209.2021.1979595"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":25,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1080\/13880209.2021.1979595"],"URL":"https:\/\/doi.org\/10.1080\/13880209.2021.1979595","relation":{},"ISSN":["1388-0209","1744-5116"],"issn-type":[{"value":"1388-0209","type":"print"},{"value":"1744-5116","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iphb20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iphb20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2020-11-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-09-07","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-09-28","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}