{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T06:37:47Z","timestamp":1769150267149,"version":"3.49.0"},"reference-count":60,"publisher":"Informa UK Limited","issue":"12","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Opinion on Pharmacotherapy"],"published-print":{"date-parts":[[2020,8,12]]},"DOI":"10.1080\/14656566.2020.1763304","type":"journal-article","created":{"date-parts":[[2020,6,16]],"date-time":"2020-06-16T15:53:29Z","timestamp":1592322809000},"page":"1399-1405","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":14,"title":["An evaluation of dimethyl fumarate for the treatment of relapsing remitting multiple sclerosis"],"prefix":"10.1080","volume":"21","author":[{"given":"Cristina","family":"Valencia-Sanchez","sequence":"first","affiliation":[{"name":"Department of Neurology, Mayo Clinic Arizona,  Mayo Foundation for Medical Education and Research , Scottsdale, AZ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan L.","family":"Carter","sequence":"additional","affiliation":[{"name":"Department of Neurology, Mayo Clinic Arizona,  Mayo Foundation for Medical Education and Research , Scottsdale, AZ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2020,6,16]]},"reference":[{"key":"cit0001","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200009283431307"},{"key":"cit0002","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000000768"},{"key":"cit0003","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000005347"},{"key":"cit0004","doi-asserted-by":"publisher","DOI":"10.1177\/1352458517751049"},{"key":"cit0005","unstructured":"Medications . National multiple sclerosis society. [Last cited 2019 Nov 16 ]; Available at https:\/\/www.nationalmssociety.org\/Treating-MS\/Medications"},{"key":"cit0006","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-019-09395-w"},{"key":"cit0007","doi-asserted-by":"publisher","DOI":"10.1007\/s40263-018-0541-5"},{"key":"cit0008","doi-asserted-by":"publisher","DOI":"10.1111\/j.1610-0387.2012.07996.x"},{"key":"cit0009","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2006.01292.x"},{"key":"cit0010","doi-asserted-by":"publisher","DOI":"10.1002\/med.21567"},{"key":"cit0011","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2018.07.001"},{"key":"cit0012","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2018.00005"},{"key":"cit0013","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2011.02.017"},{"key":"cit0014","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awq386"},{"key":"cit0015","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2017.09.009"},{"key":"cit0016","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.383380"},{"key":"cit0017","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-015-1422-3"},{"key":"cit0018","doi-asserted-by":"publisher","DOI":"10.1172\/JCI72151"},{"key":"cit0019","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5700686"},{"key":"cit0020","doi-asserted-by":"publisher","DOI":"10.1126\/science.aan4665"},{"key":"cit0021","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1601532"},{"key":"cit0022","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000007262"},{"key":"cit0023","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-019-0521-4"},{"key":"cit0024","doi-asserted-by":"publisher","DOI":"10.1002\/acn3.411"},{"key":"cit0025","doi-asserted-by":"publisher","DOI":"10.1177\/1352458517707069"},{"key":"cit0026","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1601649"},{"key":"cit0027","doi-asserted-by":"publisher","DOI":"10.1177\/1352458517703799"},{"key":"cit0028","doi-asserted-by":"publisher","DOI":"10.1177\/1352458517717088"},{"key":"cit0029","unstructured":"Biogen . Tecfidera (Biogen Inc.): FDA package insert. 2019; [Last cited 2019 Nov 16 ]; Available at https:\/\/medlibrary.org\/lib\/rx\/meds\/tecfidera\/"},{"key":"cit0030","doi-asserted-by":"publisher","DOI":"10.1007\/s11910-013-0394-8"},{"key":"cit0031","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)61619-0"},{"key":"cit0032","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1114287"},{"key":"cit0033","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1206328"},{"key":"cit0034","doi-asserted-by":"publisher","DOI":"10.1517\/14656566.2013.826190"},{"key":"cit0035","doi-asserted-by":"publisher","DOI":"10.1111\/ene.13272"},{"key":"cit0036","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2017.06.012"},{"key":"cit0037","doi-asserted-by":"publisher","DOI":"10.1177\/1352458516649037"},{"key":"cit0038","doi-asserted-by":"publisher","DOI":"10.1177\/2055217317715485"},{"key":"cit0039","doi-asserted-by":"publisher","DOI":"10.1212\/CPJ.0000000000000487"},{"key":"cit0040","doi-asserted-by":"publisher","DOI":"10.1080\/03007995.2016.1248380"},{"key":"cit0041","doi-asserted-by":"publisher","DOI":"10.1185\/03007995.2013.863755"},{"key":"cit0042","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000005772"},{"key":"cit0043","doi-asserted-by":"publisher","DOI":"10.1016\/j.msard.2016.06.001"},{"key":"cit0044","doi-asserted-by":"publisher","DOI":"10.1007\/s40120-017-0064-x"},{"key":"cit0045","doi-asserted-by":"publisher","DOI":"10.1016\/j.msard.2018.09.038"},{"key":"cit0046","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2016-013430"},{"key":"cit0047","doi-asserted-by":"publisher","DOI":"10.1016\/j.msard.2016.10.010"},{"key":"cit0048","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2018-319831"},{"key":"cit0049","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2013.08.009"},{"key":"cit0050","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2015.03.028"},{"key":"cit0051","doi-asserted-by":"publisher","DOI":"10.7224\/1537-2073.2014-101"},{"key":"cit0052","doi-asserted-by":"publisher","DOI":"10.1177\/1756286418768775"},{"key":"cit0053","doi-asserted-by":"publisher","DOI":"10.1212\/CPJ.0000000000000238"},{"key":"cit0054","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc1415408"},{"key":"cit0055","doi-asserted-by":"publisher","DOI":"10.1016\/j.msard.2017.01.006"},{"key":"cit0056","doi-asserted-by":"publisher","DOI":"10.1212\/NXI.0000000000000274"},{"key":"cit0057","doi-asserted-by":"publisher","DOI":"10.1177\/1352458519852100"},{"key":"cit0058","doi-asserted-by":"publisher","DOI":"10.1177\/1352458518786075"},{"key":"cit0059","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2019.01.007"},{"key":"cit0060","unstructured":"[cited 2020 Apr 15]. Available from: https:\/\/www.ema.europa.eu\/en\/medicines\/human\/EPAR\/tecfidera"}],"container-title":["Expert Opinion on Pharmacotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/14656566.2020.1763304","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,14]],"date-time":"2020-08-14T16:16:10Z","timestamp":1597421770000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/14656566.2020.1763304"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,16]]},"references-count":60,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2020,8,12]]}},"alternative-id":["10.1080\/14656566.2020.1763304"],"URL":"https:\/\/doi.org\/10.1080\/14656566.2020.1763304","relation":{},"ISSN":["1465-6566","1744-7666"],"issn-type":[{"value":"1465-6566","type":"print"},{"value":"1744-7666","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,6,16]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ieop20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ieop20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2019-11-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-04-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}