{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,4]],"date-time":"2025-07-04T04:06:27Z","timestamp":1751601987428,"version":"3.41.0"},"reference-count":103,"publisher":"Informa UK Limited","issue":"7","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Opinion on Pharmacotherapy"],"published-print":{"date-parts":[[2025,5,3]]},"DOI":"10.1080\/14656566.2025.2492335","type":"journal-article","created":{"date-parts":[[2025,4,11]],"date-time":"2025-04-11T01:30:40Z","timestamp":1744335040000},"page":"863-878","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":0,"title":["Current update on pharmacological strategies of penile cancer"],"prefix":"10.1080","volume":"26","author":[{"given":"Sameer S.","family":"Deshmukh","sequence":"first","affiliation":[{"name":"O\u2019Neal Comprehensive Cancer Center at UAB","place":["Birmingham, USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaustubh S.","family":"Chaudhari","sequence":"additional","affiliation":[{"name":"Dr Vaishampayan Memorial Government Medical College","place":["Solapur, India"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arnab","family":"Basu","sequence":"additional","affiliation":[{"name":"O\u2019Neal Comprehensive Cancer Center at UAB","place":["Birmingham, USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guru P.","family":"Sonpavde","sequence":"additional","affiliation":[{"name":"AdventHealth Central Florida","place":["Orlando, USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2025,4,15]]},"reference":[{"key":"e_1_3_5_2_1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"e_1_3_5_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10552-011-9785-9"},{"key":"e_1_3_5_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-008-0302-z"},{"key":"e_1_3_5_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/MOU.0000000000000581"},{"key":"e_1_3_5_6_1","volume-title":"Penile cancer and penile intraepithelial neoplasia","author":"Engelsgjerd JS","year":"2025","unstructured":"Engelsgjerd JS, Leslie SW, LaGrange CA. Penile cancer and penile intraepithelial neoplasia. Treasure Island (FL): StatPearls; 2025."},{"key":"e_1_3_5_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-021-00246-5"},{"key":"e_1_3_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2013.07.088"},{"key":"e_1_3_5_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00345-008-0310-z"},{"key":"e_1_3_5_10_1","doi-asserted-by":"publisher","DOI":"10.3238\/arztebl.2018.0646"},{"key":"e_1_3_5_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/17588359221127254"},{"key":"e_1_3_5_12_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2022.910335"},{"key":"e_1_3_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ucl.2010.04.003"},{"key":"e_1_3_5_14_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181cdad23"},{"key":"e_1_3_5_15_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18081777"},{"key":"e_1_3_5_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urolonc.2013.08.010"},{"key":"e_1_3_5_17_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-1032-3"},{"key":"e_1_3_5_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3182113402"},{"key":"e_1_3_5_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2014.08.087"},{"key":"e_1_3_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2011.10.149"},{"key":"e_1_3_5_21_1","doi-asserted-by":"publisher","DOI":"10.21037\/tau.2017.06.27"},{"key":"e_1_3_5_22_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23010251"},{"key":"e_1_3_5_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/mc.23185"},{"key":"e_1_3_5_24_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-15-1004"},{"key":"e_1_3_5_25_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-20-4004"},{"key":"e_1_3_5_26_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-15-3134"},{"key":"e_1_3_5_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-018-0736-1"},{"key":"e_1_3_5_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-025-89760-0"},{"key":"e_1_3_5_29_1","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-20-0522"},{"key":"e_1_3_5_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-443-15504-8.00005-3"},{"key":"e_1_3_5_31_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2023.48002"},{"key":"e_1_3_5_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2018.04.004"},{"key":"e_1_3_5_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/cas.16160"},{"key":"e_1_3_5_34_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.34982"},{"key":"e_1_3_5_35_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.29.5477"},{"key":"e_1_3_5_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40487-020-00135-z"},{"key":"e_1_3_5_37_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2013.620"},{"key":"e_1_3_5_38_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.4802"},{"key":"e_1_3_5_39_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23073818"},{"key":"e_1_3_5_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2013.07.012"},{"key":"e_1_3_5_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clgc.2015.08.001"},{"key":"e_1_3_5_42_1","doi-asserted-by":"publisher","DOI":"10.1517\/14712598.2015.993377"},{"key":"e_1_3_5_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2011.08.028"},{"key":"e_1_3_5_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/bju.14013"},{"key":"e_1_3_5_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2011.09.027"},{"key":"e_1_3_5_46_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12032-013-0702-9"},{"key":"e_1_3_5_47_1","doi-asserted-by":"publisher","DOI":"10.1159\/000315432"},{"key":"e_1_3_5_48_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.1055235"},{"key":"e_1_3_5_49_1","doi-asserted-by":"publisher","DOI":"10.1590\/s1677-5538.ibju.2022.99.17"},{"key":"e_1_3_5_50_1","unstructured":"Thomas WPE Abern M Agarwal N et al. Penile cancer version 2.2022. 2022."},{"key":"e_1_3_5_51_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1501824"},{"key":"e_1_3_5_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2016.09.088"},{"key":"e_1_3_5_53_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.22.02894"},{"key":"e_1_3_5_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annonc.2020.07.002"},{"key":"e_1_3_5_55_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2020.38.6_suppl.TPS7"},{"key":"e_1_3_5_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0007-4551(20)30282-4"},{"key":"e_1_3_5_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crimmu.2022.05.003"},{"key":"e_1_3_5_58_1","doi-asserted-by":"publisher","DOI":"10.1159\/000503254"},{"key":"e_1_3_5_59_1","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.33328"},{"key":"e_1_3_5_60_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2012.00021"},{"key":"e_1_3_5_61_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.20.01652"},{"key":"e_1_3_5_62_1","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdy551"},{"key":"e_1_3_5_63_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2024.42.16_suppl.5009"},{"key":"e_1_3_5_64_1","volume-title":"Trials in Progress Poster Session C: Renal Cell Cancer; Adrenal, Penile, Urethral, and Testicular Cancers. 2024 ASCO Genitourinary Symposium","author":"Amit Bahl EF","year":"2025","unstructured":"Amit Bahl EF, Ashurst L, Renninson E, et al. A phase II trial of cemiplimab alone or in combination with standard of care chemotherapy in locally advanced or metastatic penile carcinoma (EPIC trial). In: Trials in Progress Poster Session C: Renal Cell Cancer; Adrenal, Penile, Urethral, and Testicular Cancers. 2024 ASCO Genitourinary Symposium; San Francisco; 2025."},{"key":"e_1_3_5_65_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2022.40.16_suppl.5037"},{"key":"e_1_3_5_66_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra072067"},{"key":"e_1_3_5_67_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrg816"},{"key":"e_1_3_5_68_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells10040814"},{"key":"e_1_3_5_69_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.809761"},{"key":"e_1_3_5_70_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2019.00385"},{"key":"e_1_3_5_71_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2023.41.16_suppl.9125"},{"key":"e_1_3_5_72_1","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/20.24.6969"},{"key":"e_1_3_5_73_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.646384"},{"key":"e_1_3_5_74_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2020.00732"},{"key":"e_1_3_5_75_1","doi-asserted-by":"publisher","DOI":"10.1080\/21645515.2018.1551671"},{"key":"e_1_3_5_76_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2002788"},{"key":"e_1_3_5_77_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1188049"},{"key":"e_1_3_5_78_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41585-022-00617-x"},{"key":"e_1_3_5_79_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI32446"},{"key":"e_1_3_5_80_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-020-01225-1"},{"key":"e_1_3_5_81_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2024.1352805"},{"key":"e_1_3_5_82_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-022-00947-7"},{"key":"e_1_3_5_83_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1814213"},{"key":"e_1_3_5_84_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.20.03489"},{"key":"e_1_3_5_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euros.2022.12.008"},{"key":"e_1_3_5_86_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40262-024-01369-0"},{"key":"e_1_3_5_87_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2035807"},{"key":"e_1_3_5_88_1","doi-asserted-by":"publisher","DOI":"10.1177\/2515135518763280"},{"key":"e_1_3_5_89_1","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-20-1209"},{"issue":"2","key":"e_1_3_5_90_1","first-page":"A553","article-title":"523\u2005Preliminary clinical experience with XmAb20717, a PD-1 x CTLA-4 bispecific antibody, in patients with advanced solid tumors","volume":"9","author":"Shum E","year":"2021","unstructured":"Shum E, Reilley M, Najjar Y, et al. 523\u2005Preliminary clinical experience with XmAb20717, a PD-1 x CTLA-4 bispecific antibody, in patients with advanced solid tumors. J Immunother Cancer. 2021;9(Suppl 2):A553\u2013A553.","journal-title":"J Immunother Cancer"},{"key":"e_1_3_5_91_1","doi-asserted-by":"publisher","DOI":"10.1158\/1538-7445.AM2018-2784"},{"key":"e_1_3_5_92_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2008.063149"},{"key":"e_1_3_5_93_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-12-2606"},{"key":"e_1_3_5_94_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2018.4051"},{"key":"e_1_3_5_95_1","doi-asserted-by":"publisher","DOI":"10.1158\/1538-7445.AM2022-3284"},{"key":"e_1_3_5_96_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2022.829520"},{"key":"e_1_3_5_97_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10637-017-0495-3"},{"key":"e_1_3_5_98_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2020.38.15_suppl.3515"},{"key":"e_1_3_5_99_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2019.04.006"},{"key":"e_1_3_5_100_1","doi-asserted-by":"publisher","DOI":"10.2217\/fon-2019-0633"},{"key":"e_1_3_5_101_1","doi-asserted-by":"publisher","DOI":"10.1200\/OP.23.00585"},{"key":"e_1_3_5_102_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djad155"},{"key":"e_1_3_5_103_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41585-021-00557-y"},{"key":"e_1_3_5_104_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajur.2022.03.006"}],"container-title":["Expert Opinion on Pharmacotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/14656566.2025.2492335","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T12:54:22Z","timestamp":1751547262000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/14656566.2025.2492335"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,15]]},"references-count":103,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,5,3]]}},"alternative-id":["10.1080\/14656566.2025.2492335"],"URL":"https:\/\/doi.org\/10.1080\/14656566.2025.2492335","relation":{},"ISSN":["1465-6566","1744-7666"],"issn-type":[{"type":"print","value":"1465-6566"},{"type":"electronic","value":"1744-7666"}],"subject":[],"published":{"date-parts":[[2025,4,15]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ieop20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ieop20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2025-01-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-04-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}