{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T22:27:48Z","timestamp":1785796068938,"version":"3.56.0"},"reference-count":73,"publisher":"Informa UK Limited","issue":"9","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Opinion on Biological Therapy"],"published-print":{"date-parts":[[2016,9]]},"DOI":"10.1080\/14712598.2016.1196182","type":"journal-article","created":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T23:06:21Z","timestamp":1464822381000},"page":"1125-1134","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":29,"title":["Anti-sense oligonucleotide therapies for the treatment of hyperlipidaemia"],"prefix":"10.1080","volume":"16","author":[{"given":"Anthony S.","family":"Wierzbicki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adie","family":"Viljoen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2016,6,9]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2015.12.1344"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa031766"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1097\/FJC.0b013e3181a8184c"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1210\/en.2008-1512"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0706628"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1517\/13543784.2012.679340"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1039\/c3ra47841f"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.4155\/fmc.15.144"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.75.1.280"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.75.1.285"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-60327-369-5_14"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1111\/imr.12375"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1089\/nat.2015.0598"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0101749"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)61350-5"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)60656-3"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1410489"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehr112"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.04.064"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2008.10.002"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2012.12.023"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000018744.58460.62"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosissup.2012.10.001"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1007\/s40262-014-0224-4"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1007\/s00228-015-1992-y"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aad2195"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)60284-X"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehr148"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/eht549"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacl.2014.12.008"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacl.2014.12.006"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacl.2014.08.002"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.R026658"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.12738"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)61914-5"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2013.124"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1097\/MED.0000000000000237"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehq386"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2009.801"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.09.038"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchf.2015.08.006"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.03.061"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.2174\/138161211795428777"},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.R052258"},{"key":"CIT0045","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.114.304549"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)61252-1"},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1308027"},{"key":"CIT0048","doi-asserted-by":"publisher","DOI":"10.1586\/erc.12.21"},{"key":"CIT0049","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.P021717"},{"key":"CIT0050","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.111.300367"},{"key":"CIT0051","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1400283"},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.M066399"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1400284"},{"key":"CIT0054","first-page":"489","volume":"13","author":"Birch AM","year":"2010","journal-title":"Curr Opin Drug Discov Devel"},{"key":"CIT0055","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2007.09.080"},{"key":"CIT0056","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20783"},{"key":"CIT0057","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M704213200"},{"key":"CIT0058","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21655"},{"key":"CIT0059","doi-asserted-by":"crossref","first-page":"4","DOI":"10.3389\/fendo.2014.00004","volume":"5","author":"Santulli G","year":"2014","journal-title":"Front Endocrinol (Lausanne)"},{"key":"CIT0060","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.P066183"},{"key":"CIT0061","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2015.04.115"},{"key":"CIT0062","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.M054882"},{"key":"CIT0063","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacl.2016.03.091"},{"key":"CIT0064","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2012.11.019"},{"key":"CIT0065","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbalip.2016.02.006"},{"key":"CIT0066","doi-asserted-by":"publisher","DOI":"10.1002\/hep.25846"},{"key":"CIT0067","doi-asserted-by":"publisher","DOI":"10.1038\/nature10486"},{"key":"CIT0068","doi-asserted-by":"publisher","DOI":"10.1172\/JCI57275"},{"key":"CIT0069","doi-asserted-by":"publisher","DOI":"10.1172\/JCI81676"},{"key":"CIT0070","doi-asserted-by":"publisher","DOI":"10.2174\/157016109788340703"},{"key":"CIT0071","doi-asserted-by":"publisher","DOI":"10.1517\/14712598.2013.738663"},{"key":"CIT0072","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.M008961"},{"key":"CIT0073","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.113.002432"}],"container-title":["Expert Opinion on Biological Therapy"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/14712598.2016.1196182","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,9]],"date-time":"2019-09-09T04:10:59Z","timestamp":1568002259000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/14712598.2016.1196182"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6,9]]},"references-count":73,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2016,6,13]]},"published-print":{"date-parts":[[2016,9]]}},"alternative-id":["10.1080\/14712598.2016.1196182"],"URL":"https:\/\/doi.org\/10.1080\/14712598.2016.1196182","relation":{},"ISSN":["1471-2598","1744-7682"],"issn-type":[{"value":"1471-2598","type":"print"},{"value":"1744-7682","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,6,9]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iebt20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iebt20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"}]}}