{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T22:54:50Z","timestamp":1787007290168,"version":"build-2736575974"},"reference-count":77,"publisher":"Informa UK Limited","issue":"1","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Opinion on Biological Therapy"],"published-print":{"date-parts":[[2020,1,2]]},"DOI":"10.1080\/14712598.2020.1677603","type":"journal-article","created":{"date-parts":[[2019,10,14]],"date-time":"2019-10-14T06:02:24Z","timestamp":1571032944000},"page":"15-22","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":23,"title":["The role of PIGF blockade in the treatment of colorectal cancer: overcoming the pitfalls"],"prefix":"10.1080","volume":"20","author":[{"given":"Teresa","family":"Macarulla","sequence":"first","affiliation":[{"name":"Vall d\u00b4Hebron University Hospital (HUVH) and Vall d\u2019Hebron Institute of Oncology (VHIO), Universitat Aut\u00f2noma de Barcelona, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara","family":"Montagut","sequence":"additional","affiliation":[{"name":"Hospital del Mar, Barcelona, Spain"},{"name":"Institut Mar d\u2019Investigacions M\u00e8diques (IMIM), Barcelona, Spain"},{"name":"Universitat Pompeu Fabra, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco Javier","family":"S\u00e1nchez-Martin","sequence":"additional","affiliation":[{"name":"Institut Mar d\u2019Investigacions M\u00e8diques (IMIM), Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00f3nica","family":"Granja","sequence":"additional","affiliation":[{"name":"Hospital Clinico San Carlos, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helena","family":"Verdaguer","sequence":"additional","affiliation":[{"name":"Vall d\u00b4Hebron University Hospital (HUVH) and Vall d\u2019Hebron Institute of Oncology (VHIO), Universitat Aut\u00f2noma de Barcelona, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Sastre","sequence":"additional","affiliation":[{"name":"Hospital Clinico San Carlos, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josep","family":"Tabernero","sequence":"additional","affiliation":[{"name":"Vall d\u00b4Hebron University Hospital (HUVH) and Vall d\u2019Hebron Institute of Oncology (VHIO), Universitat Aut\u00f2noma de Barcelona, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2019,10,16]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdy033"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21442"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdw235"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.25516"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.4MR0316-102R"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.2174\/1566524033479465"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2011.02.013"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i15.4189"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1038\/nm0603-669"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M008055200"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1038\/nrm1911"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.52.12.2959"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.107.158022"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1016\/j.exphem.2004.03.005"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1201545"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjp.0706347"},{"key":"CIT0017","first-page":"1207","volume":"61","author":"Hiratsuka S","year":"2001","journal-title":"Cancer Res"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-11-3423"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.4137\/CMO.S7432"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.2174\/157488408784293705"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a006502"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(00)01246-1"},{"key":"CIT0023","first-page":"3:972","author":"Cudmore MJ","year":"2012","journal-title":"Nat Commun"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.108.171504"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.2174\/1389450116666150325231555"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2011.12.026"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.16.9.4604"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1210\/er.2003-0027"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1038\/nrc2524"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1111\/cas.13585"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1007\/s11010-017-3145-3"},{"key":"CIT0032","first-page":"239","volume":"38","author":"Soukup V","year":"2018","journal-title":"Anticancer Res"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-011-1761-9"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.3906\/sag-1509-80"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.3892\/ijo.2016.3362"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1038\/nm884"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1038\/nature10144"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.1517\/14728222.2012.656092"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1038\/380435a0"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.1038\/87904"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1038\/nm740"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.1038\/nature04186"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.1038\/nm731"},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.1177\/1758834016676703"},{"key":"CIT0045","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2012-0003"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2006.09.6305"},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(12)70477-1"},{"key":"CIT0048","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2008.16.3212"},{"key":"CIT0049","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2005.09.005"},{"key":"CIT0050","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.259re1"},{"key":"CIT0051","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.24.8252"},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.1811"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.1007\/s10147-011-0331-2"},{"key":"CIT0054","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2011.85"},{"key":"CIT0055","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0077117"},{"key":"CIT0056","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2007.08.038"},{"key":"CIT0057","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2010.02.039"},{"key":"CIT0058","first-page":"1370","volume":"70","author":"Rizzo C","year":"2010","journal-title":"AACR"},{"key":"CIT0059","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-12-2911"},{"key":"CIT0060","doi-asserted-by":"publisher","DOI":"10.1007\/s10456-011-9249-6"},{"key":"CIT0061","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.172398299"},{"key":"CIT0062","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1432908100"},{"key":"CIT0063","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2011.12.008"},{"key":"CIT0064","doi-asserted-by":"publisher","DOI":"10.1007\/s10456-012-9328-3"},{"key":"CIT0065","doi-asserted-by":"publisher","DOI":"10.4161\/cbt.10.12.14009"},{"key":"CIT0066","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-13-0753"},{"key":"CIT0067","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2012.42.8201"},{"key":"CIT0068","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2014.10.019"},{"key":"CIT0069","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2013.09.013"},{"key":"CIT0070","doi-asserted-by":"publisher","DOI":"10.1200\/jco.2015.33.3_suppl.638"},{"key":"CIT0071","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2017.35.4_suppl.592"},{"key":"CIT0072","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2017.35.15_suppl.3538"},{"key":"CIT0073","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(15)70127-0"},{"key":"CIT0074","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdx767"},{"key":"CIT0075","doi-asserted-by":"publisher","DOI":"10.1517\/13543784.2012.684752"},{"key":"CIT0076","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)61900-X"},{"key":"CIT0077","doi-asserted-by":"crossref","first-page":"478P","DOI":"10.1093\/annonc\/mdy281.026","volume":"29","author":"Mata Velasco E","year":"2018","journal-title":"Ann Oncol"}],"container-title":["Expert Opinion on Biological Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/14712598.2020.1677603","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,12,4]],"date-time":"2019-12-04T10:08:54Z","timestamp":1575454134000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/14712598.2020.1677603"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,16]]},"references-count":77,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1,2]]}},"alternative-id":["10.1080\/14712598.2020.1677603"],"URL":"https:\/\/doi.org\/10.1080\/14712598.2020.1677603","relation":{},"ISSN":["1471-2598","1744-7682"],"issn-type":[{"value":"1471-2598","type":"print"},{"value":"1744-7682","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,16]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iebt20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iebt20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2019-06-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-10-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-10-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}