{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T14:59:13Z","timestamp":1766415553428,"version":"3.48.0"},"reference-count":18,"publisher":"Informa UK Limited","issue":"11","funder":[{"DOI":"10.13039\/501100003197","name":"Italian Medicines Agency","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003197","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Opinion on Biological Therapy"],"published-print":{"date-parts":[[2025,11,2]]},"DOI":"10.1080\/14712598.2025.2583283","type":"journal-article","created":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T09:07:38Z","timestamp":1761901658000},"page":"1241-1247","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":0,"title":["Ten-year trend of rituximab use for hematological malignancies: a multiregional real-world study using the Italian VALORE distributed database network"],"prefix":"10.1080","volume":"25","author":[{"given":"Federica","family":"Soardo","sequence":"first","affiliation":[{"name":"University of Verona","place":["Verona, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Spini","sequence":"additional","affiliation":[{"name":"University of Verona","place":["Verona, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luca","family":"L\u2019Abbate","sequence":"additional","affiliation":[{"name":"University of Verona","place":["Verona, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiara","family":"Bellitto","sequence":"additional","affiliation":[{"name":"University of Verona","place":["Verona, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giorgia","family":"Pellegrini","sequence":"additional","affiliation":[{"name":"University of Verona","place":["Verona, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ylenia","family":"Ingrasciotta","sequence":"additional","affiliation":[{"name":"University of Verona","place":["Verona, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Paladin","sequence":"additional","affiliation":[{"name":"University of Verona","place":["Verona, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorenzo","family":"di Spazio","sequence":"additional","affiliation":[{"name":"Azienda Provinciale per i Servizi Sanitari","place":["Trento, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annalisa","family":"Campomori","sequence":"additional","affiliation":[{"name":"Azienda Provinciale per i Servizi Sanitari","place":["Trento, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvana Anna Maria","family":"Urru","sequence":"additional","affiliation":[{"name":"Azienda Provinciale per i Servizi Sanitari","place":["Trento, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olivia","family":"Leoni","sequence":"additional","affiliation":[{"name":"Lombardy Regional Epidemiologic Observatory","place":["Milan, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martina","family":"Zanforlini","sequence":"additional","affiliation":[{"name":"Azienda Regionale per l\u2019Innovazione E Gli Acquisti, S.p.A","place":["Milan, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Domenica","family":"Ancona","sequence":"additional","affiliation":[{"name":"Centro Regionale Farmacovigilanza, Regione Puglia","place":["Bari, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Stella","sequence":"additional","affiliation":[{"name":"Centro Regionale Farmacovigilanza, Regione Puglia","place":["Bari, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Cavazzana","sequence":"additional","affiliation":[{"name":"Regione Veneto","place":["Padova, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Angela","family":"Scapin","sequence":"additional","affiliation":[{"name":"Regione Veneto","place":["Padova, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Lopes","sequence":"additional","affiliation":[{"name":"Lazio Regional Health Service","place":["Rome, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valeria","family":"Belleudi","sequence":"additional","affiliation":[{"name":"Lazio Regional Health Service","place":["Rome, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Ledda","sequence":"additional","affiliation":[{"name":"Regione Autonoma della Sardegna","place":["Cagliari, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paolo","family":"Carta","sequence":"additional","affiliation":[{"name":"Regione Autonoma della Sardegna","place":["Cagliari, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola","family":"Rossi","sequence":"additional","affiliation":[{"name":"Friuli-Venezia Giulia Regional Center of Pharmacovigilance","place":["Trieste, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucian","family":"Ejlli","sequence":"additional","affiliation":[{"name":"Friuli-Venezia Giulia Regional Center of Pharmacovigilance","place":["Trieste, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ester","family":"Sapigni","sequence":"additional","affiliation":[{"name":"Emilia-Romagna Regional Center of Pharmacovigilance","place":["Bologna, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aurora","family":"Puccini","sequence":"additional","affiliation":[{"name":"Emilia-Romagna Regional Center of Pharmacovigilance","place":["Bologna, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ugo","family":"Trama","sequence":"additional","affiliation":[{"name":"General Directorate for Health Protection","place":["Naples, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesca Futura","family":"Bernardi","sequence":"additional","affiliation":[{"name":"General Directorate for Health Protection","place":["Naples, Italy"]},{"name":"University of Campania Luigi Vanvitelli","place":["Naples, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antea Maria Pia","family":"Mangano","sequence":"additional","affiliation":[{"name":"Agenzia Regionale Sanitaria della Regione Marche","place":["Ancona, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Balducci","sequence":"additional","affiliation":[{"name":"Agenzia Regionale Sanitaria della Regione Marche","place":["Ancona, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefania","family":"Spila-Alegiani","sequence":"additional","affiliation":[{"name":"Italian National Institute of Health","place":["Rome, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marco","family":"Massari","sequence":"additional","affiliation":[{"name":"Italian National Institute of Health","place":["Rome, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiara","family":"Alberti","sequence":"additional","affiliation":[{"name":"Azienda Ospedaliera Universitaria Integrata","place":["Verona, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mauro","family":"Krampera","sequence":"additional","affiliation":[{"name":"University of Verona","place":["Verona, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianluca","family":"Trifir\u00f2","sequence":"additional","affiliation":[{"name":"University of Verona","place":["Verona, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2025,11,5]]},"reference":[{"key":"e_1_3_8_2_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2018.00163"},{"key":"e_1_3_8_3_1","doi-asserted-by":"publisher","DOI":"10.18553\/jmcp.2020.26.7.832"},{"key":"e_1_3_8_4_1","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2017-0150"},{"issue":"3","key":"e_1_3_8_5_1","first-page":"148","article-title":"Impact of rituximab (Rituxan) on the treatment of B-cell non-Hodgkin\u2019s lymphoma","volume":"35","author":"Dotan E","year":"2010","unstructured":"Dotan E, Aggarwal C, Smith MR. Impact of rituximab (Rituxan) on the treatment of B-cell non-Hodgkin\u2019s lymphoma. Pharm Ther. 2010;35(3):148\u2013157.","journal-title":"Pharm Ther"},{"key":"e_1_3_8_6_1","unstructured":"mabthera-epar-product-information_it.pdf [Internet]. [cited 2023 May 15 Available from: https:\/\/www.ema.europa.eu\/en\/documents\/product-information\/mabthera-epar-product-information_it.pdf"},{"key":"e_1_3_8_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0229973"},{"key":"e_1_3_8_8_1","doi-asserted-by":"publisher","DOI":"10.2217\/fon-2020-0180"},{"key":"e_1_3_8_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40259-021-00498-3"},{"issue":"2","key":"e_1_3_8_10_1","first-page":"39","article-title":"TheShinISS: un applicativo open-source per la conduzione di analisi distribuite in studi di farmacoepidemiologia di tipo multi-database","volume":"1","author":"Massari M","unstructured":"Massari M, Spila Alegiani S, Da Cas R, et al. TheShinISS: un applicativo open-source per la conduzione di analisi distribuite in studi di farmacoepidemiologia di tipo multi-database. BEN \u2014\u2014-. 1(2):39\u201345.","journal-title":"BEN \u2014\u2014-"},{"key":"e_1_3_8_11_1","unstructured":"Resident population. 2022 [Internet]. [cited 2025 Apr 28 2025]. Available from: https:\/\/demo.istat.it\/app\/?l=en&a=2022&i=POS"},{"key":"e_1_3_8_12_1","unstructured":"Giunta regionale Emilia-Romagna del 13\/11\/2017. 2017 [Internet]. [cited 2025 Apr 28 2025]. Available from: https:\/\/salute.regione.emilia-romagna.it\/ssr\/strumenti-e-informazioni\/ptr\/archivio\/atti-regionali-e-documenti-ptr\/determina-18246-2017"},{"key":"e_1_3_8_13_1","unstructured":"Rapporto OsMed. 2022 [Internet]. [cited 2024 Dec 4]. Available from: https:\/\/www.aifa.gov.it\/documents\/20142\/2143103\/Rapporto-OsMed-2022_EN.pdf"},{"key":"e_1_3_8_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofaf255"},{"key":"e_1_3_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2665-9913(21)00418-5"},{"key":"e_1_3_8_16_1","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13133134"},{"key":"e_1_3_8_17_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1313984"},{"key":"e_1_3_8_18_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2023.1059109"},{"key":"e_1_3_8_19_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2023023568"}],"container-title":["Expert Opinion on Biological Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/14712598.2025.2583283","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,22]],"date-time":"2025-12-22T14:50:44Z","timestamp":1766415044000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/14712598.2025.2583283"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,2]]},"references-count":18,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11,2]]}},"alternative-id":["10.1080\/14712598.2025.2583283"],"URL":"https:\/\/doi.org\/10.1080\/14712598.2025.2583283","relation":{},"ISSN":["1471-2598","1744-7682"],"issn-type":[{"type":"print","value":"1471-2598"},{"type":"electronic","value":"1744-7682"}],"subject":[],"published":{"date-parts":[[2025,11,2]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iebt20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iebt20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2025-06-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-28","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-05","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}