{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,16]],"date-time":"2026-08-16T14:13:37Z","timestamp":1786889617155,"version":"build-2736575974"},"reference-count":130,"publisher":"Informa UK Limited","issue":"5","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Opinion on Therapeutic Targets"],"published-print":{"date-parts":[[2020,5,3]]},"DOI":"10.1080\/14728222.2020.1744850","type":"journal-article","created":{"date-parts":[[2020,3,18]],"date-time":"2020-03-18T21:11:26Z","timestamp":1584565886000},"page":"451-462","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":21,"title":["The bone marrow stromal niche: a therapeutic target of hematological myeloid malignancies"],"prefix":"10.1080","volume":"24","author":[{"given":"Lena","family":"Behrmann","sequence":"first","affiliation":[{"name":"Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald University Cancer Center, University Medical Center Hamburg Eppendorf, Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasmin","family":"Wellbrock","sequence":"additional","affiliation":[{"name":"Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald University Cancer Center, University Medical Center Hamburg Eppendorf, Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walter","family":"Fiedler","sequence":"additional","affiliation":[{"name":"Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, Hubertus Wald University Cancer Center, University Medical Center Hamburg Eppendorf, Hamburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2020,3,26]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-09-670224"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2017.197"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-12-304"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1038\/ng0709-766"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2015-07-533588"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1016\/j.leukres.2015.06.017"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(94)00430-S"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3155"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2014.02.018"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1015350108"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1111\/nyas.13016"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1097\/MOH.0000000000000438"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2005.05.026"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1038\/ncb2730"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V97.8.2293"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1038\/nature04247"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2008.10.048"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-08-303800"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.2741\/3913"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1038\/nature02040"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1038\/nature02041"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.090225"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1111\/ejh.12109"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2010.02.001"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V124.21.620.620"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.4061\/2011\/375857"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1080\/14653240600855905"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1038\/nature09262"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.03696"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1016\/j.stemcr.2015.09.018"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1152\/physiol.00025.2005"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1038\/nature15250"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1016\/j.leukres.2015.12.012"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3707"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20150057"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2015.01.026"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20101688"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20101700"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1007\/s11914-018-0442-z"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2014.06.003"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2019.224188"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.178.6.3511"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.25905"},{"key":"CIT0044","first-page":"783","volume":"110","author":"Germing U","year":"2013","journal-title":"Dtsch Arztebl Int"},{"key":"CIT0045","doi-asserted-by":"publisher","DOI":"10.1038\/nature08851"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2011.08.030"},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-017-2725-4"},{"key":"CIT0048","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2016.91"},{"key":"CIT0049","volume":"1","author":"Wang J","year":"2014","journal-title":"Stem Cell Investig"},{"key":"CIT0050","doi-asserted-by":"publisher","DOI":"10.1016\/j.leukres.2003.11.019"},{"key":"CIT0051","doi-asserted-by":"publisher","DOI":"10.1016\/j.exphem.2013.10.002"},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2014.02.014"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(17)30615-0"},{"key":"CIT0054","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-10-696005"},{"key":"CIT0055","doi-asserted-by":"publisher","DOI":"10.1186\/s40364-019-0166-y"},{"key":"CIT0056","doi-asserted-by":"crossref","DOI":"10.1186\/s13045-014-0092-2","volume":"7","author":"Schneider RK","year":"2014","journal-title":"J Hematol Oncol"},{"key":"CIT0057","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-14-3696"},{"key":"CIT0058","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2018-02-834820"},{"key":"CIT0059","doi-asserted-by":"publisher","DOI":"10.1038\/nature13383"},{"key":"CIT0060","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/869242","volume":"2015","author":"Hoermann G","year":"2015","journal-title":"Mediators Inflamm"},{"key":"CIT0061","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2018.00444","volume":"8","author":"Behrmann L","year":"2018","journal-title":"Front Oncol"},{"key":"CIT0062","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1406184"},{"key":"CIT0063","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1592"},{"key":"CIT0064","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-01-202606"},{"key":"CIT0065","doi-asserted-by":"publisher","DOI":"10.1016\/j.exphem.2006.10.012"},{"key":"CIT0066","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.90036","volume":"2","author":"Battula VL","year":"2017","journal-title":"JCI Insight"},{"key":"CIT0067","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2011.09.053"},{"key":"CIT0068","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2014.06.020"},{"key":"CIT0069","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V95.8.2637"},{"key":"CIT0070","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2017.11.006"},{"key":"CIT0071","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2017.08.001"},{"key":"CIT0072","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2014.109"},{"key":"CIT0073","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V89.6.1870"},{"key":"CIT0074","doi-asserted-by":"crossref","DOI":"10.3390\/cells8040312","volume":"8","author":"Terao T","year":"2019","journal-title":"Cells"},{"key":"CIT0075","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-14-1059"},{"key":"CIT0076","doi-asserted-by":"publisher","DOI":"10.1016\/j.exphem.2009.09.008"},{"key":"CIT0077","doi-asserted-by":"crossref","DOI":"10.1186\/s13046-016-0405-0","volume":"35","author":"Zhai Y","year":"2016","journal-title":"J Exp Clin Cancer Res"},{"key":"CIT0078","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-08-734798"},{"key":"CIT0079","doi-asserted-by":"publisher","DOI":"10.1038\/ncb3625"},{"key":"CIT0080","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.12246"},{"key":"CIT0081","doi-asserted-by":"publisher","DOI":"10.1586\/17474086.2014.958464"},{"key":"CIT0082","doi-asserted-by":"publisher","DOI":"10.2217\/imt-2016-0001"},{"key":"CIT0083","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-03-206672"},{"key":"CIT0084","doi-asserted-by":"publisher","DOI":"10.1038\/cdd.2014.89"},{"key":"CIT0085","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2015.05.007"},{"key":"CIT0086","doi-asserted-by":"publisher","DOI":"10.1038\/nm1483"},{"key":"CIT0087","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.8687"},{"key":"CIT0088","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-06-511527"},{"key":"CIT0089","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2013.06.009"},{"key":"CIT0090","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2012.02.018"},{"key":"CIT0091","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3364"},{"key":"CIT0092","doi-asserted-by":"publisher","DOI":"10.7150\/thno.5150"},{"key":"CIT0093","doi-asserted-by":"publisher","DOI":"10.1007\/s12254-014-0142-z"},{"key":"CIT0094","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2005.05.058"},{"key":"CIT0095","doi-asserted-by":"publisher","DOI":"10.1200\/jco.2014.32.15_suppl.7082"},{"key":"CIT0096","doi-asserted-by":"publisher","DOI":"10.2174\/156800911798073078"},{"key":"CIT0097","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2404632"},{"key":"CIT0098","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-03-0627"},{"key":"CIT0099","doi-asserted-by":"publisher","DOI":"10.2147\/CMAR.S168610"},{"key":"CIT0100","doi-asserted-by":"publisher","DOI":"10.1038\/s41375-018-0312-9"},{"key":"CIT0101","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V126.23.1004.1004"},{"key":"CIT0102","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2019.37.15_suppl.TPS7066"},{"key":"CIT0103","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V118.21.82.82"},{"key":"CIT0104","doi-asserted-by":"publisher","DOI":"10.1177\/2040620715619307"},{"key":"CIT0105","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V128.22.5220.5220"},{"key":"CIT0106","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-13-2159"},{"key":"CIT0107","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3239"},{"key":"CIT0108","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-07-4079"},{"key":"CIT0109","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-09-0547"},{"key":"CIT0110","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-02-337691"},{"key":"CIT0111","doi-asserted-by":"publisher","DOI":"10.1097\/MOH.0000000000000401"},{"key":"CIT0112","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-08-523548"},{"key":"CIT0113","doi-asserted-by":"publisher","DOI":"10.1038\/s41388-018-0288-y"},{"key":"CIT0114","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0137345"},{"key":"CIT0115","doi-asserted-by":"publisher","DOI":"10.1016\/j.leukres.2013.04.008"},{"key":"CIT0116","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2019.37.15_suppl.7009"},{"key":"CIT0117","doi-asserted-by":"crossref","DOI":"10.1186\/s12915-019-0670-4","volume":"17","author":"Stuani L","year":"2019","journal-title":"BMC Biol"},{"key":"CIT0118","doi-asserted-by":"publisher","DOI":"10.1126\/science.1147949"},{"key":"CIT0119","doi-asserted-by":"publisher","DOI":"10.1111\/ejh.12711"},{"key":"CIT0120","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-14-3378"},{"key":"CIT0121","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-11591-1"},{"key":"CIT0122","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-019-1104-8"},{"key":"CIT0123","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2019000176"},{"key":"CIT0124","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2019.04.040"},{"key":"CIT0126","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-1971-z"},{"key":"CIT0127","doi-asserted-by":"crossref","DOI":"10.3390\/diseases6020042","volume":"6","author":"Lundstrom K","year":"2018","journal-title":"Diseases"},{"key":"CIT0128","doi-asserted-by":"publisher","DOI":"10.15252\/emmm.201506078"},{"key":"CIT0129","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2017.088"},{"key":"CIT0130","doi-asserted-by":"publisher","DOI":"10.1016\/j.stemcr.2017.09.014"},{"key":"CIT0131","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2013.10.010"}],"container-title":["Expert Opinion on Therapeutic Targets"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/14728222.2020.1744850","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,20]],"date-time":"2020-04-20T23:27:49Z","timestamp":1587425269000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/14728222.2020.1744850"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3,26]]},"references-count":130,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,5,3]]}},"alternative-id":["10.1080\/14728222.2020.1744850"],"URL":"https:\/\/doi.org\/10.1080\/14728222.2020.1744850","relation":{},"ISSN":["1472-8222","1744-7631"],"issn-type":[{"value":"1472-8222","type":"print"},{"value":"1744-7631","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3,26]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iett20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iett20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2019-12-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-03-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-03-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}