{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T23:58:16Z","timestamp":1772755096684,"version":"3.50.1"},"reference-count":77,"publisher":"Informa UK Limited","issue":"9","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Opinion on Drug Safety"],"published-print":{"date-parts":[[2017,9,2]]},"DOI":"10.1080\/14740338.2017.1344213","type":"journal-article","created":{"date-parts":[[2017,6,19]],"date-time":"2017-06-19T13:16:02Z","timestamp":1497878162000},"page":"1079-1088","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":8,"title":["The safety of Bruton\u2019s tyrosine kinase inhibitors for the treatment of chronic lymphocytic leukemia"],"prefix":"10.1080","volume":"16","author":[{"given":"Phu N.","family":"Tran","sequence":"first","affiliation":[{"name":"Division of Hematology-Oncology, University of California Irvine, Orange, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan","family":"O\u2019Brien","sequence":"additional","affiliation":[{"name":"Division of Hematology-Oncology, University of California Irvine, Orange, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2017,6,23]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21332"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-10-386417"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2012-05-423194"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-05-284984"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1084\/jem.194.11.1639"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-06-1683"},{"issue":"6","key":"CIT0008","doi-asserted-by":"crossref","first-page":"1580","DOI":"10.1182\/blood.V85.6.1580.bloodjournal8561580","volume":"85","author":"Dohner H","year":"1995","journal-title":"Blood"},{"issue":"11","key":"CIT0009","doi-asserted-by":"crossref","first-page":"4342","DOI":"10.1182\/blood.V91.11.4342","volume":"91","author":"Cordone I","year":"1998","journal-title":"Blood"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(20010115)91:2<285::AID-CNCR1000>3.0.CO;2-X"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200012283432602"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2015-05-647578"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-01-546150"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2012-02-362624"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.43.30644"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2172-2-4"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M009137200"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20011866"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.immunol.021908.132649"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.2217\/fon.14.51"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1004594107"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-01-328484"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-15-1965"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1111\/sji.12333"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1215637"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1007\/s00280-015-2708-9"},{"key":"CIT0029","doi-asserted-by":"crossref","unstructured":"Mikudina B, Goodall M, Adler AI. NICE guidance on ibrutinib for previously treated chronic lymphocytic leukaemia and untreated chronic lymphocytic leukaemia in the presence of 17p deletion or TP53 mutation. The\u00a0Lancet Oncology. 2017;18(3):289\u2013290.","DOI":"10.1016\/S1470-2045(17)30062-1"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1509388"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1400376"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(16)30212-1"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1038\/bcj.2017.5"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2015.273"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1159\/000452437"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-09-527853"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(15)00465-9"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-10-604272"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-04-1142"},{"issue":"5","key":"CIT0041","first-page":"1663","volume":"95","author":"Oda A","year":"2000","journal-title":"Blood"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-01-011817"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-06-583294"},{"key":"CIT0045","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.14660"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)00667-4"},{"key":"CIT0047","author":"Yun S","journal-title":"Clin Lymphoma Myeloma Leuk"},{"key":"CIT0048","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.24715"},{"key":"CIT0049","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2014.218"},{"key":"CIT0051","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.30596"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.14540"},{"key":"CIT0054","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1509981"},{"key":"CIT0056","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1315226"},{"key":"CIT0057","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1513257"},{"key":"CIT0058","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2009.26.4556"},{"key":"CIT0059","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-06-507947"},{"key":"CIT0060","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2015-04-639203"},{"key":"CIT0061","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-06-722991"},{"key":"CIT0062","volume":"78","author":"de J\u00e9sus Ngoma P","year":"2015","journal-title":"Acta Gastroenterol Belg"},{"key":"CIT0063","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-08-591875"},{"key":"CIT0064","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-16-1431"},{"key":"CIT0065","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-10-606038"},{"key":"CIT0066","doi-asserted-by":"publisher","DOI":"10.1080\/10428194.2017.1292353"},{"key":"CIT0067","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1400029"},{"key":"CIT0069","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-09-693598"},{"key":"CIT0070","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-06-719294"},{"key":"CIT0071","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms11589"},{"key":"CIT0072","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-09-603670"},{"issue":"8","key":"CIT0073","doi-asserted-by":"crossref","first-page":"12953","DOI":"10.18632\/oncotarget.14588","volume":"8","author":"Guo A","year":"2017","journal-title":"Oncotarget"},{"key":"CIT0074","doi-asserted-by":"publisher","DOI":"10.3109\/10428194.2015.1022770"},{"issue":"23","key":"CIT0075","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1182\/blood.V126.23.497.497","volume":"126","author":"Lampson BL","year":"2015","journal-title":"Blood"},{"key":"CIT0076","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000525"},{"key":"CIT0077","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000522"},{"key":"CIT0081","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.33.8061"},{"key":"CIT0082","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-06-093906"},{"key":"CIT0083","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2015-06-651125"},{"key":"CIT0084","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2015-05-647925"},{"key":"CIT0085","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2015-09-667675"},{"issue":"5","key":"CIT0086","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1245\/s10434-016-5649-6","volume":"28","author":"Mato A","year":"2017","journal-title":"Ann Oncol"},{"key":"CIT0087","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-05-716977"},{"issue":"22","key":"CIT0088","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1182\/blood.V128.22.637.637","volume":"128","author":"Jones J","year":"2016","journal-title":"Blood"},{"key":"CIT0089","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2015-08-634816"}],"container-title":["Expert Opinion on Drug Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/14740338.2017.1344213","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,10]],"date-time":"2020-10-10T11:03:36Z","timestamp":1602327816000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/14740338.2017.1344213"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6,23]]},"references-count":77,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2017,7,24]]},"published-print":{"date-parts":[[2017,9,2]]}},"alternative-id":["10.1080\/14740338.2017.1344213"],"URL":"https:\/\/doi.org\/10.1080\/14740338.2017.1344213","relation":{},"ISSN":["1474-0338","1744-764X"],"issn-type":[{"value":"1474-0338","type":"print"},{"value":"1744-764X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,6,23]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ieds20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ieds20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"}]}}