{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T12:50:46Z","timestamp":1792673446394,"version":"4.5.0"},"reference-count":221,"publisher":"Informa UK Limited","issue":"1","funder":[{"DOI":"10.13039\/100010438","name":"Francis Crick Institute","doi-asserted-by":"publisher","award":["FC0010218"],"award-info":[{"award-number":["FC0010218"]}],"id":[{"id":"10.13039\/100010438","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U01AI115949"],"award-info":[{"award-number":["U01AI115949"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004440","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["203135"],"award-info":[{"award-number":["203135"]}],"id":[{"id":"10.13039\/100004440","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004440","name":"Wellcome Trust","doi-asserted-by":"publisher","award":["104803"],"award-info":[{"award-number":["104803"]}],"id":[{"id":"10.13039\/100004440","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Opinion on Drug Safety"],"published-print":{"date-parts":[[2020,1,2]]},"DOI":"10.1080\/14740338.2020.1694901","type":"journal-article","created":{"date-parts":[[2019,12,6]],"date-time":"2019-12-06T16:50:54Z","timestamp":1575651054000},"page":"23-41","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":47,"title":["Safety implications of combined antiretroviral and anti-tuberculosis drugs"],"prefix":"10.1080","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6900-6086","authenticated-orcid":false,"given":"Maddalena","family":"Cerrone","sequence":"first","affiliation":[{"name":"Department of Medicine, Imperial College London, London, UK"},{"name":"Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine and Department of Medicine, University of Cape Town, Observatory, South Africa"},{"name":"Department of HIV, Chelsea and Westminster Hospital NHS Trust, London, UK"},{"name":"The Francis Crick Institute, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margherita","family":"Bracchi","sequence":"additional","affiliation":[{"name":"Department of HIV, Chelsea and Westminster Hospital NHS Trust, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3508-6719","authenticated-orcid":false,"given":"Sean","family":"Wasserman","sequence":"additional","affiliation":[{"name":"Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine and Department of Medicine, University of Cape Town, Observatory, South Africa"},{"name":"Division of Infectious Diseases and HIV Medicine, Department of Medicine, University of Cape Town, Cape Town, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anton","family":"Pozniak","sequence":"additional","affiliation":[{"name":"Department of HIV, Chelsea and Westminster Hospital NHS Trust, London, UK"},{"name":"The London School of Hygiene & Tropical Medicine, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graeme","family":"Meintjes","sequence":"additional","affiliation":[{"name":"Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine and Department of Medicine, University of Cape Town, Observatory, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1892-4207","authenticated-orcid":false,"given":"Karen","family":"Cohen","sequence":"additional","affiliation":[{"name":"Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, Rondebosch, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2753-1800","authenticated-orcid":false,"given":"Robert J","family":"Wilkinson","sequence":"additional","affiliation":[{"name":"Department of Medicine, Imperial College London, London, UK"},{"name":"Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine and Department of Medicine, University of Cape Town, Observatory, South Africa"},{"name":"The Francis Crick Institute, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2019,12,6]]},"reference":[{"key":"cit0001","unstructured":"WHO Organization. Fact sheets - Tuberculosis [Internet]. 2018 [cited 2019 May 30]. Available from: https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/tuberculosis"},{"key":"cit0002","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/1471-2334-9-46","volume":"9","author":"Zhou J","year":"2009","journal-title":"BMC Infect Dis"},{"key":"cit0003","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1097\/01.qai.0000230521.86964.86","volume":"43","author":"Manosuthi W","year":"2006","journal-title":"JAIDS J Acquir Immune Defic Syndr"},{"key":"cit0004","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.jinf.2005.05.010","volume":"52","author":"Sungkanuparph S","year":"2006","journal-title":"J Infect"},{"key":"cit0005","doi-asserted-by":"crossref","first-page":"e5146","DOI":"10.1097\/MD.0000000000005146","volume":"95","author":"Wang H","year":"2016","journal-title":"Medicine (Baltimore)"},{"key":"cit0006","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1016\/S0140-6736(13)62187-X","volume":"383","author":"Amin J","year":"2014","journal-title":"Lancet"},{"key":"cit0007","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1002\/cpt.156","volume":"98","author":"Dickinson L","year":"2015","journal-title":"Clin Pharmacol Ther"},{"key":"cit0008","volume-title":"Conf. Retrovir. Opportunistic Infect Seattle, 2019 March 4\u20137","author":"Orkin C","year":"2019"},{"key":"cit0009","unstructured":"World Health Organization. WHO global tuberculosis report 2018. [cited 2019 Nov 26]. Available from: https:\/\/reliefweb.int\/sites\/reliefweb.int\/files\/resources\/9789241565646-eng.pdf"},{"key":"cit0010","first-page":"86","volume":"24","author":"Tiberi S","year":"2018","journal-title":"Rev Port Pneumol"},{"key":"cit0011","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1164\/rccm.201001-0077OC","volume":"182","author":"Van Deun A","year":"2010","journal-title":"Am J Respir Crit Care Med"},{"key":"cit0012","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1097\/COH.0000000000000503","volume":"13","author":"Hurtado RM","year":"2018","journal-title":"Curr Opin HIV AIDS"},{"key":"cit0013","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1164\/rccm.200907-0989OC","volume":"181","author":"Gandhi NR","year":"2010","journal-title":"Am J Respir Crit Care Med"},{"key":"cit0014","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.1016\/S0140-6736(06)69573-1","volume":"368","author":"Gandhi NR","year":"2006","journal-title":"Lancet"},{"key":"cit0015","doi-asserted-by":"crossref","first-page":"S63","DOI":"10.1086\/518655","volume":"196","author":"McIlleron H","year":"2007","journal-title":"J Infect Dis"},{"key":"cit0016","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1007\/s00228-011-1166-5","volume":"68","author":"Gengiah TN","year":"2012","journal-title":"Eur J Clin Pharmacol"},{"key":"cit0017","doi-asserted-by":"crossref","first-page":"819","DOI":"10.2165\/00003088-200342090-00003","volume":"42","author":"Niemi M","year":"2003","journal-title":"Clin Pharmacokinet"},{"issue":"2","key":"cit0018","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1097\/MAJ.0b013e31814a586a","volume":"335","author":"Baciewicz AM","year":"2008","journal-title":"Am J Med Sci"},{"key":"cit0019","doi-asserted-by":"crossref","first-page":"2852","DOI":"10.1128\/AAC.01468-08","volume":"53","author":"Wenning LA","year":"2009","journal-title":"Antimicrob Agents Chemother"},{"key":"cit0020","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1172\/JCI6663","volume":"104","author":"Greiner B","year":"1999","journal-title":"J Clin Invest"},{"key":"cit0021","doi-asserted-by":"crossref","first-page":"1670","DOI":"10.1093\/jac\/dkz068","volume":"74","author":"Cerrone M","year":"2019","journal-title":"J Antimicrob Chemother"},{"key":"cit0022","unstructured":"Gilead sciences. Descovy - summary of product characteristics [Internet]. [cited 2019 May 30]. Available from: https:\/\/www.medicines.org.uk\/emc\/product\/2108\/smpc"},{"key":"cit0023","doi-asserted-by":"crossref","first-page":"1492","DOI":"10.1056\/NEJMoa1014181","volume":"365","author":"Gengiah T","year":"2011","journal-title":"N Engl J Med"},{"key":"cit0024","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1056\/NEJMoa1013911","volume":"365","author":"Blanc F-X","year":"2011","journal-title":"N Engl J Med"},{"key":"cit0025","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1056\/NEJMoa1013607","volume":"365","author":"Havlir DV","year":"2011","journal-title":"N Engl J Med"},{"key":"cit0026","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/S1473-3099(14)70733-9","volume":"14","author":"Mfinanga SG","year":"2014","journal-title":"Lancet Infect Dis"},{"key":"cit0027","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1001\/jama.300.5.530","volume":"300","author":"Boulle A","year":"2008","journal-title":"JAMA - J Am Med Assoc"},{"key":"cit0028","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1124\/jpet.103.049601","volume":"306","author":"Ward BA","year":"2003","journal-title":"J Pharmacol Exp Ther"},{"key":"cit0029","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1124\/jpet.106.107573","volume":"319","author":"Itoh M","year":"2006","journal-title":"J Pharmacol Exp Ther"},{"key":"cit0030","doi-asserted-by":"crossref","first-page":"681","DOI":"10.2165\/00003088-200241090-00004","volume":"41","author":"Lopez-Cortes LF","year":"2002","journal-title":"Clin Pharmacokinet"},{"key":"cit0031","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1093\/cid\/cit246","volume":"57","author":"Luetkemeyer AF","year":"2013","journal-title":"Clin Infect Dis"},{"key":"cit0032","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1128\/AAC.02023-12","volume":"57","author":"Manosuthi W","year":"2013","journal-title":"Antimicrob Agents Chemother"},{"key":"cit0033","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1097\/00002030-200101050-00011","volume":"15","author":"Marzolini C","year":"2001","journal-title":"AIDS"},{"key":"cit0034","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1093\/cid\/ciy491","volume":"68","author":"Cerrone M","year":"2019","journal-title":"Clin Infect Dis"},{"issue":"2","key":"cit0035","doi-asserted-by":"crossref","first-page":"ofz035","DOI":"10.1093\/ofid\/ofz035","volume":"6","author":"Kaboggoza JP","year":"2019","journal-title":"Open Forum Infect Dis"},{"key":"cit0036","first-page":"87","volume":"15","author":"Crauwels H","year":"2013","journal-title":"AIDS Rev"},{"key":"cit0037","doi-asserted-by":"crossref","first-page":"25","DOI":"10.2165\/11534740-000000000-00000","volume":"50","author":"Kakuda TN","year":"2011","journal-title":"Clin Pharmacokinet"},{"key":"cit0038","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1007\/s40261-017-0513-4","volume":"37","author":"Yee KL","year":"2017","journal-title":"Clin Drug Investig"},{"key":"cit0039","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1002\/jcph.1103","volume":"58","author":"Khalilieh SG","year":"2018","journal-title":"J Clin Pharmacol"},{"key":"cit0040","unstructured":"ViiV Healthcare UK Ltd. Tivicay, summary of product characteristics [Internet]. 2019 [cited 2019 May 30]. Available from: https:\/\/www.medicines.org.uk\/emc\/product\/5248\/smpc"},{"key":"cit0041","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/S1473-3099(14)70711-X","volume":"14","author":"Grinsztejn B","year":"2014","journal-title":"Lancet Infect Dis"},{"key":"cit0042","author":"Dooley KE","year":"2019","journal-title":"Clin Infect Dis"},{"key":"cit0043","author":"Wang X","year":"2019","journal-title":"Int J Antimicrob Agents"},{"key":"cit0044","unstructured":"Gilead Sciences Ltd. Stribild - summary of product characteristics [Internet]. 2019 [cited 2019 May 30]. Available from: https:\/\/www.medicines.org.uk\/emc\/product\/3154\/smpc"},{"key":"cit0045","volume-title":"Conf. Retrovir. Opportunistic Infect","author":"Custodio JM","year":"2019"},{"key":"cit0046","unstructured":"Gilead Sciences Ltd. Biktarvy - summary of product characteristics [Internet]. [cited 2019 May 27]. Available from: https:\/\/www.medicines.org.uk\/emc\/product\/9313\/smpc"},{"key":"cit0047","first-page":"Abstract 40","volume-title":"Conf. Retrovir. Opportunistic Infect","author":"Zhang H"},{"key":"cit0048","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.01598-10","volume":"55","author":"Decloedt EH","year":"2011","journal-title":"Antimicrob Agents Chemother"},{"key":"cit0049","author":"La Porte CJL","year":"2004","journal-title":"Antimicrob Agents Chemother"},{"key":"cit0050","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1097\/QAI.0000000000000944","volume":"72","author":"Yapa HM","year":"2016","journal-title":"J Acquir Immune Defic Syndr"},{"key":"cit0051","unstructured":"European AIDS Clinical Society. European AIDS clinical society (EACS) guidelines. Version 10 [Internet]. [cited 2019 Nov 26]. Available from: https:\/\/www.eacsociety.org\/files\/2019_guidelines-10.0_final.pdf"},{"key":"cit0052","first-page":"s2","author":"BHIVA","year":"2019","journal-title":"HIV Med"},{"key":"cit0053","unstructured":"Gilead Sciences Ltd. Tybost - summary of product characteristics [Internet]. 2019 [cited 2019 May 30]. Available from: https:\/\/www.medicines.org.uk\/emc\/product\/1277\/smpc."},{"key":"cit0054","volume":"61","author":"Ford SL","year":"2017","journal-title":"Antimicrob Agents Chemother"},{"key":"cit0055","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1056\/NEJMoa1711460","volume":"379","author":"Emu B","year":"2018","journal-title":"N Engl J Med"},{"key":"cit0056","doi-asserted-by":"crossref","first-page":"133","DOI":"10.3109\/00498254.2016.1166532","volume":"47","author":"Yang W","year":"2017","journal-title":"Xenobiotica"},{"key":"cit0057","volume-title":"14th Int. Work. Clin. Pharmacol. HIV Ther","author":"Hruska M","year":"2013"},{"key":"cit0058","doi-asserted-by":"crossref","unstructured":"Adamczyk R, Griffies A, Ravindran P et al. HIV-1 attachment inhibitor prodrug BMS-663068: interactions with rifabutin, with or without ritonavir, in healthy subjects. IAS 2015: 8th IAS Conference on\u00a0HIV Pathogenesis Treatment and Prevention.\u00a0Vancouver, Canada,\u00a018-22 July 2015.","DOI":"10.7448\/IAS.18.5.20479"},{"key":"cit0059","doi-asserted-by":"crossref","DOI":"10.1097\/QAD.0b013e328360dbb4","volume":"27","author":"McIlleron HM","year":"2013","journal-title":"AIDS"},{"key":"cit0060","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1053\/S0882-0546(03)00073-2","volume":"18","author":"COHN D","year":"2003","journal-title":"Semin Respir Infect"},{"key":"cit0061","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1038\/clpt.2011.323","volume":"91","author":"Dooley KE","year":"2012","journal-title":"Clin Pharmacol Ther"},{"key":"cit0062","first-page":"1650","volume":"60","author":"Centers for Disease Control and Prevention (CDC)","year":"2011","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"cit0063","volume-title":"Conf. Retrovir. Opportunistic Infect","author":"Swindells S","year":"2018"},{"key":"cit0064","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.1093\/cid\/civ464","volume":"61","author":"Podany AT","year":"2015","journal-title":"Clin Infect Dis"},{"key":"cit0065","unstructured":"Farenc C, Doroumian S, Cantalloube C, et al. Rifapentine once-weekly dosing effect on efavirenz, emtricitabine and tenofovir PKs. Conference on Retroviruses and Opportunistic Infections,\u00a0March 3-6,\u00a02014. p. 233\u2013234. Available from:\u00a0 http:\/\/www.croiconference.org\/sessions\/rifapentine-once-weekly-dosing-effect-efavirenz-emtricitabine-and-tenofovir-pks\u00a0."},{"key":"cit0066","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1093\/jac\/dkt483","volume":"69","author":"Weiner M","year":"2014","journal-title":"J Antimicrob Chemother"},{"key":"cit0067","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1093\/cid\/ciy082","volume":"67","author":"Brooks KM","year":"2018","journal-title":"Clin Infect Dis"},{"key":"cit0068","first-page":"Abstract number","volume-title":"Conf. Retrovir. Opportunistic Infect; March 4\u20137; Seattle","author":"Dooley KE","year":"2019"},{"key":"cit0069","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1097\/QAD.0b013e328326ca50","volume":"23","author":"Coyne KM","year":"2009","journal-title":"AIDS"},{"key":"cit0070","doi-asserted-by":"crossref","first-page":"1441","DOI":"10.1093\/jac\/dkx004","volume":"72","author":"Naidoo A","year":"2017","journal-title":"J Antimicrob Chemother"},{"key":"cit0071","author":"Schnippel K","year":"2018","journal-title":"Lancet Respir Med"},{"key":"cit0072","doi-asserted-by":"crossref","first-page":"2310","DOI":"10.1093\/jac\/dku171","volume":"69","author":"van Heeswijk RPG","year":"2014","journal-title":"J Antimicrob Chemother"},{"key":"cit0073","doi-asserted-by":"crossref","first-page":"275","DOI":"10.2165\/00003088-199835040-00002","volume":"35","author":"Hsu A","year":"1998","journal-title":"Clin Pharmacokinet"},{"key":"cit0074","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1124\/dmd.110.037523","author":"Kirby BJ","year":"2011","journal-title":"Drug Metab Dispos"},{"key":"cit0075","doi-asserted-by":"crossref","first-page":"18567","DOI":"10.7448\/IAS.16.1.18567","volume":"16","author":"Usach I","year":"2013","journal-title":"J Int AIDS Soc"},{"key":"cit0076","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1097\/QAI.0b013e3182410503","volume":"59","author":"Dooley KE","year":"2012","journal-title":"J Acquir Immune Defic Syndr"},{"key":"cit0077","doi-asserted-by":"crossref","first-page":"2780","DOI":"10.1128\/AAC.00191-13","volume":"57","author":"Svensson EM","year":"2013","journal-title":"Antimicrob Agents Chemother"},{"key":"cit0078","doi-asserted-by":"crossref","first-page":"6406","DOI":"10.1128\/AAC.03246-14","volume":"58","author":"Svensson EM","year":"2014","journal-title":"Antimicrob Agents Chemother"},{"key":"cit0079","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1093\/jac\/dkv447","volume":"71","author":"Pandie M","year":"2016","journal-title":"J Antimicrob Chemother"},{"key":"cit0080","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1093\/jac\/dks404","volume":"68","author":"Sharma M","year":"2013","journal-title":"J Antimicrob Chemother"},{"key":"cit0081","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.ijantimicag.2016.10.020","volume":"49","author":"Brill MJE","year":"2017","journal-title":"Int J Antimicrob Agents"},{"key":"cit0082","unstructured":"Mesens N, Verbeeck J, Rouan M, et al. Elucidating the role of M2 in the preclinical safety profile of TMC207. 38th Union World Conference on Lung Health, Cape Town, South Africa; 2007. p. 8\u201312. [cited 2019 Nov 26]. Available from: https:\/\/www.theunion.org\/what-we-do\/journals\/ijtld\/body\/Abstract-Book-2007.pdf"},{"key":"cit0083","first-page":"2016","volume-title":"Tuberc. PK 2018; 2018 Oct 23; Netherlands","author":"Tanneau L","year":"2016"},{"key":"cit0084","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1093\/jac\/45.5.557","volume":"45","author":"Ball P","year":"2000","journal-title":"J Antimicrob Chemother"},{"key":"cit0085","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1067\/mcp.2000.111482","volume":"68","author":"D\u00e9molis JL","year":"2000","journal-title":"Clin Pharmacol Ther"},{"key":"cit0086","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1164\/rccm.201410-1801OC","volume":"191","author":"Diacon AH","year":"2015","journal-title":"Am J Respir Crit Care Med"},{"key":"cit0087","volume":"677","author":"Lynch J","year":"2015","journal-title":"Drug Des Devel Ther"},{"key":"cit0088","volume-title":"52nd Intersci. Conf. Antimicrob. Agents Chemother","author":"Dannemann B","year":"2012"},{"key":"cit0089","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1016\/S1473-3099(18)30100-2","volume":"18","author":"Ferlazzo G","year":"2018","journal-title":"Lancet Infect Dis"},{"key":"cit0090","first-page":"1","volume-title":"Conf. Retrovir. Opportunistic Infect","author":"Dooley KE","year":"2019"},{"key":"cit0091","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1124\/dmd.115.064527","volume":"43","author":"Sasahara K","year":"2015","journal-title":"Drug Metab Dispos"},{"key":"cit0092","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1124\/dmd.115.064550","volume":"43","author":"Shimokawa Y","year":"2015","journal-title":"Drug Metab Dispos"},{"key":"cit0093","volume":"37","author":"Sasabe H","year":"2016","journal-title":"Antimicrob Agents Chemother"},{"key":"cit0094","doi-asserted-by":"crossref","first-page":"1727","DOI":"10.1248\/bpb.b14-00311","volume":"37","author":"Shimokawa Y","year":"2014","journal-title":"Biol Pharm Bull"},{"key":"cit0095","first-page":"22","volume-title":"19th Int. AIDS Conf., Washington, DC","author":"Paccaly A","year":"2012"},{"key":"cit0096","doi-asserted-by":"crossref","first-page":"5976","DOI":"10.1128\/AAC.00509-16","volume":"60","author":"Mallikaarjun S","year":"2016","journal-title":"Antimicrob Agents Chemother"},{"key":"cit0097","doi-asserted-by":"crossref","first-page":"5245","DOI":"10.1128\/AAC.03332-14","volume":"58","author":"Dooley KE","year":"2014","journal-title":"Antimicrob Agents Chemother"},{"key":"cit0098","unstructured":"WHO Organization. WHO consolidated guidelines on drug-resistant tuberculosis treatment [Internet]. 2019. [cited 2019 Jul 1]. Available from: https:\/\/www.who.int\/tb\/publications\/2019\/consolidated-guidelines-drug-resistant-TB-treatment\/en\/"},{"key":"cit0099","first-page":"1136","volume":"29","author":"Slatter JG","year":"2001","journal-title":"Drug Metab Dispos"},{"key":"cit0100","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1177\/0091270010366445","volume":"51","author":"Gandelman K","year":"2011","journal-title":"J Clin Pharmacol"},{"key":"cit0101","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1183\/09031936.00001913","volume":"42","author":"Bolhuis MS","year":"2013","journal-title":"Eur Respir J"},{"key":"cit0102","doi-asserted-by":"crossref","DOI":"10.1128\/AAC.02164-18","volume":"63","author":"Wasserman S","year":"2019","journal-title":"Antimicrob Agents Chemother"},{"key":"cit0103","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1183\/09031936.00188114","volume":"46","author":"Hughes J","year":"2015","journal-title":"Eur Respir J"},{"key":"cit0104","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1097\/00002030-199814000-00004","author":"Brinkman K","year":"1998","journal-title":"AIDS"},{"key":"cit0105","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1080\/14787210.2016.1225498","author":"Wasserman S","year":"2016","journal-title":"Expert Rev Anti Infect Ther"},{"key":"cit0106","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1086\/501356","volume":"42","author":"De Vriese AS","year":"2006","journal-title":"Clin Infect Dis"},{"key":"cit0107","doi-asserted-by":"crossref","first-page":"74","DOI":"10.2165\/00003088-198916020-00002","author":"Holdiness MR","year":"1989","journal-title":"Clin Pharmacokinet"},{"key":"cit0108","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.tube.2015.08.004","volume":"96","author":"Te Brake LHM","year":"2016","journal-title":"Tuberculosis"},{"key":"cit0109","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1248\/bpb.b15-00313","volume":"38","author":"Shimokawa Y","year":"2015","journal-title":"Biol Pharm Bull"},{"key":"cit0110","doi-asserted-by":"crossref","first-page":"3168","DOI":"10.1128\/AAC.02278-13","volume":"58","author":"Horita Y","year":"2014","journal-title":"Antimicrob Agents Chemother"},{"key":"cit0111","doi-asserted-by":"crossref","first-page":"26","DOI":"10.5588\/ijtld.17.0615","volume":"22","author":"Maartens G","year":"2017","journal-title":"Int J Tuberc Lung Dis"},{"key":"cit0112","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1186\/s12879-016-1933-0","volume":"16","author":"Schnippel K","year":"2016","journal-title":"BMC Infect Dis"},{"key":"cit0113","doi-asserted-by":"crossref","first-page":"e40781","DOI":"10.1371\/journal.pone.0040781","volume":"7","author":"Isaakidis P","year":"2012","journal-title":"PLoS One"},{"key":"cit0114","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/s40264-015-0267-y","volume":"38","author":"Ramachandran G","year":"2015","journal-title":"Drug Saf"},{"key":"cit0115","doi-asserted-by":"crossref","first-page":"43","DOI":"10.4102\/sajhivmed.v12i1.214","volume":"12","author":"Kenyon C","year":"2017","journal-title":"South Afr J HIV Med"},{"key":"cit0116","first-page":"1","volume":"2012","author":"Neuman MG","year":"2012","journal-title":"Int J Hepatol"},{"key":"cit0117","doi-asserted-by":"crossref","first-page":"105","DOI":"10.4236\/jtr.2016.43013","volume":"04","author":"Munivenkatappa S","year":"2016","journal-title":"J Tuberc Res"},{"key":"cit0118","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1590\/2359-3997000000023","volume":"59","author":"Silva GARD","year":"2015","journal-title":"Arch Endocrinol Metab"},{"key":"cit0119","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1007\/s00204-019-02407-8","volume":"93","author":"Hong H","year":"2019","journal-title":"Arch Toxicol"},{"key":"cit0120","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1111\/j.1440-1746.2007.05207.x","volume":"23","author":"Tostmann A","year":"2008","journal-title":"J Gastroenterol Hepatol"},{"key":"cit0121","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1111\/j.1440-1746.2007.05207.x","volume":"23","author":"Tostmann A","year":"2008","journal-title":"J Gastroenterol Hepatol"},{"key":"cit0122","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1164\/rccm.201105-0850OC","volume":"185","author":"Singanayagam A","year":"2012","journal-title":"Am J Respir Crit Care Med"},{"key":"cit0123","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1186\/s12879-017-2330-z","volume":"17","author":"Abbara A","year":"2017","journal-title":"BMC Infect Dis"},{"key":"cit0124","doi-asserted-by":"crossref","first-page":"e94271","DOI":"10.1371\/journal.pone.0094271","volume":"9","author":"Yimer G","year":"2014","journal-title":"PLoS One"},{"key":"cit0125","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1177\/2150131916642431","volume":"7","author":"Saha A","year":"2016","journal-title":"J Prim Care Community Heal"},{"key":"cit0126","doi-asserted-by":"crossref","first-page":"506","DOI":"10.7196\/SAMJ.5650","volume":"102","author":"Schutz C","year":"2012","journal-title":"South Afr Med J"},{"key":"cit0127","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/j.1440-1746.2012.07279.x","volume":"28","author":"Devarbhavi H","year":"2013","journal-title":"J Gastroenterol Hepatol"},{"key":"cit0128","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1164\/rccm.200510-1666ST","volume":"174","author":"Saukkonen JJ","year":"2006","journal-title":"Am J Respir Crit Care Med"},{"key":"cit0129","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.jceh.2012.12.001","author":"Ramappa V","year":"2013","journal-title":"J Clin Exp Hepatol"},{"key":"cit0130","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1055\/s-0028-1085703","volume":"29","author":"El-Sadr W","year":"2008","journal-title":"Semin Respir Crit Care Med"},{"key":"cit0131","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1136\/thx.2006.058867","volume":"61","author":"Breen RAM","year":"2006","journal-title":"Thorax"},{"key":"cit0132","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1258\/ijsa.2008.008361","volume":"20","author":"Marks DJB","year":"2009","journal-title":"Int J STD AIDS"},{"key":"cit0133","author":"Polo M","year":"2015","journal-title":"BrJ Pharmacol"},{"key":"cit0134","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1097\/QAD.0b013e32814e6b08","volume":"21","author":"Hoffmann CJ","year":"2007","journal-title":"AIDS"},{"key":"cit0135","doi-asserted-by":"crossref","first-page":"596","DOI":"10.5588\/ijtld.11.0591","volume":"16","author":"Keshavjee S","year":"2012","journal-title":"Int J Tuberc Lung Dis"},{"key":"cit0136","first-page":"1373","author":"T\u00f6r\u00fcn T","year":"2005","journal-title":"Int J Tuberc Lung Dis"},{"key":"cit0137","doi-asserted-by":"crossref","first-page":"800","DOI":"10.5588\/ijtld.15.0668","volume":"20","author":"Lee SS","year":"2016","journal-title":"Int J Tuberc Lung Dis"},{"key":"cit0138","first-page":"e7482","volume":"96","author":"Yang TW","year":"2017","journal-title":"Med(USA)"},{"key":"cit0139","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1016\/S0929-6646(10)60141-6","volume":"109","author":"Hsu HL","year":"2010","journal-title":"J Formos Med Assoc"},{"key":"cit0140","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1093\/jac\/dkt446","volume":"69","author":"Chien JY","year":"2014","journal-title":"J Antimicrob Chemother"},{"key":"cit0141","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1007\/s13181-010-0047-0","volume":"6","author":"de Bus L","year":"2010","journal-title":"J Med Toxicol"},{"key":"cit0142","doi-asserted-by":"crossref","first-page":"37","DOI":"10.2146\/ajhp130165","volume":"71","author":"Alshammari TM","year":"2014","journal-title":"Am J Health Syst Pharm"},{"key":"cit0143","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1093\/cid\/ciu786","volume":"60","author":"Guglielmetti L","year":"2015","journal-title":"Clin Infect Dis"},{"key":"cit0144","doi-asserted-by":"crossref","first-page":"113","DOI":"10.4102\/sajhivmed.v14i3.63","volume":"14","author":"Jong E","year":"2013","journal-title":"South Afr J HIV Med"},{"key":"cit0145","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1093\/cid\/ciw566","author":"Nahid P","year":"2016","journal-title":"Clin Infect Dis"},{"key":"cit0146","doi-asserted-by":"crossref","first-page":"2083","DOI":"10.2217\/pgs.15.144","author":"Shi J","year":"2015","journal-title":"Pharmacogenomics"},{"key":"cit0147","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/s12072-008-9085-y","volume":"2","author":"Makhlouf HA","year":"2008","journal-title":"Hepatol Int"},{"key":"cit0148","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.ijid.2014.06.020","volume":"28","author":"Mo P","year":"2014","journal-title":"Int J Infect Dis"},{"key":"cit0149","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1007\/s13365-011-0044-3","volume":"17","author":"Robertson K","year":"2011","journal-title":"J Neurovirol"},{"key":"cit0150","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1212\/WNL.0b013e3181f4d5bb","volume":"75","author":"Vivithanaporn P","year":"2010","journal-title":"Neurology"},{"key":"cit0151","doi-asserted-by":"crossref","first-page":"655","DOI":"10.2165\/11534340-000000000-00000","volume":"2","author":"Kass JS","year":"2010","journal-title":"CNS Drugs"},{"key":"cit0152","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.jctube.2015.11.002","author":"Mafukidze AT","year":"2016","journal-title":"J Clin Tuberc Other Mycobact Dis"},{"key":"cit0153","first-page":"PA2710","author":"Tiwari M","year":"2015","journal-title":"Eur Respir Soc"},{"key":"cit0154","first-page":"1122","volume":"4","author":"Baum MK","year":"1991","journal-title":"J Acquir Immune Defic Syndr"},{"key":"cit0155","volume":"63","author":"Daley CL","year":"2016","journal-title":"Clin Infect Dis"},{"key":"cit0156","first-page":"56","author":"Chan RYC","year":"2006","journal-title":"Chest"},{"key":"cit0157","first-page":"542","volume":"6","author":"Mustak H","year":"2013","journal-title":"Int J Ophthalmol"},{"key":"cit0158","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1136\/bjo.2006.102541","volume":"91","author":"Javaheri M","year":"2007","journal-title":"Br J Ophthalmol"},{"key":"cit0159","doi-asserted-by":"crossref","first-page":"e0162138","DOI":"10.1371\/journal.pone.0162138","volume":"11","author":"Mehta S","year":"2016","journal-title":"PLoS One"},{"key":"cit0160","first-page":"347","volume":"7","author":"Shin SS","year":"2003","journal-title":"Int J Tuberc Lung Dis"},{"key":"cit0161","doi-asserted-by":"crossref","first-page":"24","DOI":"10.7196\/samj.6455","volume":"104","author":"Conradie F","year":"2014","journal-title":"South Afr Med J"},{"key":"cit0162","doi-asserted-by":"crossref","first-page":"4","DOI":"10.24875\/AIDSRev.19000023","volume":"21","author":"Hoffmann C","year":"2019","journal-title":"AIDS Rev"},{"key":"cit0163","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1586\/14787210.2016.1157469","author":"Gaida R","year":"2016","journal-title":"Expert Rev Anti Infect Ther"},{"key":"cit0164","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1186\/1471-2334-13-261","volume":"13","author":"Mukonzo JK","year":"2013","journal-title":"BMC Infect Dis"},{"key":"cit0165","doi-asserted-by":"crossref","first-page":"149","DOI":"10.4103\/1817-1737.43083","volume":"3","author":"Prasad R","year":"2009","journal-title":"Ann Thorac Med"},{"key":"cit0166","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.5588\/ijtld.12.0863","author":"Hwang TJ","year":"2013","journal-title":"Int J Tuberc Lung Dis"},{"key":"cit0167","author":"Walmsley SL","year":"2013","journal-title":"N Engl J Med"},{"issue":"13","key":"cit0168","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1016\/j.jacc.2015.12.063","volume":"67","author":"Schwartz PJ","year":"2016","journal-title":"J Am Coll Cardiol"},{"key":"cit0169","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1089\/aid.2013.0061","volume":"29","author":"Moreno T","year":"2013","journal-title":"AIDS Res Hum Retroviruses"},{"key":"cit0170","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1097\/COH.0000000000000408","volume":"12","author":"McIntosh RC","year":"2017","journal-title":"Curr Opin HIV AIDS"},{"key":"cit0171","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1136\/heartjnl-2018-313667","volume":"105","author":"Wu KC","year":"2019","journal-title":"Heart"},{"key":"cit0172","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1007\/s15010-017-1053-9","volume":"45","author":"Reinsch N","year":"2017","journal-title":"Infection"},{"key":"cit0173","doi-asserted-by":"crossref","first-page":"539","DOI":"10.2459\/JCM.0000000000000436","volume":"18","author":"Gili S","year":"2017","journal-title":"J Cardiovasc Med"},{"key":"cit0174","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1111\/j.1365-2125.2008.03332.x","volume":"67","author":"Charbit B","year":"2009","journal-title":"Br J Clin Pharmacol"},{"key":"cit0175","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1345\/aph.1A454","volume":"36","author":"Castillo R","year":"2002","journal-title":"Ann Pharmacother"},{"key":"cit0176","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1086\/516614","volume":"44","author":"Chinello P","year":"2007","journal-title":"Clin Infect Dis"},{"key":"cit0177","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1111\/jce.13032","volume":"27","author":"Abdelhady AM","year":"2016","journal-title":"J Cardiovasc Electrophysiol"},{"key":"cit0178","doi-asserted-by":"crossref","first-page":"e67","DOI":"10.1086\/511875","volume":"44","author":"Ly T","year":"2007","journal-title":"Clin Infect Dis"},{"key":"cit0179","unstructured":"Janssen-Cilag Ltd. Edurant - summary of product characteristics [Internet]. 2019. [cited 2019 Jul 1]. Available from: https:\/\/www.medicines.org.uk\/emc\/product\/4968\/smpc"},{"key":"cit0180","unstructured":"World Health Organization. Companion handbook to the WHO guidelines for the programmatic management of drug-resistance tuberculosis [Internet]. 2014. [cited 2019 Jul 1]. Available from: https:\/\/www.who.int\/tb\/publications\/pmdt_companionhandbook\/en\/."},{"key":"cit0181","doi-asserted-by":"crossref","first-page":"54","DOI":"10.5415\/apallergy.2014.4.1.54","volume":"4","author":"Yunihastuti E","year":"2014","journal-title":"Asia Pac Allergy"},{"key":"cit0182","doi-asserted-by":"crossref","first-page":"1670","DOI":"10.1056\/NEJM199306103282304","volume":"328","author":"Coopman SA","year":"2002","journal-title":"N Engl J Med"},{"key":"cit0183","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1586\/eri.12.13","author":"Lehloenya RJ","year":"2012","journal-title":"Expert Rev Anti Infect Ther"},{"key":"cit0184","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1016\/0140-6736(91)92447-A","volume":"337","author":"Nunn P","year":"1991","journal-title":"Lancet"},{"key":"cit0185","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1136\/adc.68.5.665","volume":"68","author":"Chintu C","year":"1993","journal-title":"Arch Dis Child"},{"key":"cit0186","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1111\/j.1365-2125.2010.03784.x","volume":"71","author":"Chaponda M","year":"2011","journal-title":"Br J Clin Pharmacol"},{"key":"cit0187","doi-asserted-by":"crossref","first-page":"338","DOI":"10.5588\/ijtld.16.0425","volume":"21","author":"Boonyagars L","year":"2017","journal-title":"Int J Tuberc Lung Dis"},{"key":"cit0188","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1097\/COH.0000000000000502","volume":"13","author":"Walker NF","year":"2018","journal-title":"Curr Opin HIV AIDS"},{"key":"cit0189","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.2217\/fmb.15.9","volume":"10","author":"Namale PE","year":"2015","journal-title":"Future Microbiol"},{"key":"cit0190","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1097\/QAI.0000000000000030","volume":"65","author":"Luetkemeyer AF","year":"2014","journal-title":"JAIDS J Acquir Immune Defic Syndr"},{"key":"cit0191","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1007\/s11908-013-0378-5","volume":"15","author":"Bahr N","year":"2013","journal-title":"Curr Infect Dis Rep"},{"key":"cit0192","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1177\/2325957415599210","volume":"14","author":"Abay SM","year":"2015","journal-title":"J Int Assoc Provid AIDS Care"},{"key":"cit0193","doi-asserted-by":"crossref","first-page":"32","DOI":"10.7326\/M14-2979","volume":"163","author":"Uthman OA","year":"2015","journal-title":"Ann Intern Med"},{"key":"cit0194","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/QAD.0b013e32833dfc68","volume":"24","author":"Meintjes G","year":"2010","journal-title":"AIDS"},{"key":"cit0195","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1056\/NEJMoa1800762","volume":"379","author":"Meintjes G","year":"2018","journal-title":"N Engl J Med"},{"key":"cit0196","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1097\/COH.0000000000000445","author":"Hill AM","year":"2018","journal-title":"Curr Opin HIV AIDS"},{"key":"cit0197","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.ijid.2014.12.014","volume":"32","author":"Bates M","year":"2015","journal-title":"Int J Infect Dis"},{"key":"cit0198","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1056\/NEJMoa1811867","volume":"380","author":"Nunn AJ","year":"2019","journal-title":"N Engl J Med"},{"key":"cit0199","unstructured":"Accord-UK Ltd. Levofloxacin, Summary of Product Characteristics. 2019. [cited 2019 Jul 1]. Available from:\u00a0 https:\/\/www.medicines.org.uk\/emc\/product\/4625\/smpc"},{"key":"cit0200","unstructured":"Bayer plc. Avelox - summary of product characteristics [Internet]. 2019 [cited 2019 Jul 7]. Available from: https:\/\/www.medicines.org.uk\/emc\/product\/6771\/smpc"},{"key":"cit0201","unstructured":"Janssen-Cilag Ltd. Sirturo 100 mg - summary of product characteristics [Internet]. 2019 [cited 2019 Jul 7]. Available from: https:\/\/www.medicines.org.uk\/emc\/product\/3560\/smpc"},{"key":"cit0202","unstructured":"Pfizer. Zyvox 600 mg - summary of product characteristics [Internet]. 2018 [cited 2019 Jul 7]. Available from: https:\/\/www.medicines.org.uk\/emc\/product\/1688\/smpc."},{"key":"cit0203","unstructured":"Novartis. Lamprene - highlights of prescribing information [Internet]. 2016 [cited 2019 Jul 7]. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2016\/019500s013lbl.pdf"},{"key":"cit0204","unstructured":"King Pharmaceuticals Ltd. Cycloserine - summary of product characteristics [Internet]. 2018 [cited 2019 Jul 7]. Available from: https:\/\/www.medicines.org.uk\/emc\/product\/2252\/smpc."},{"key":"cit0205","unstructured":"Macleods Pharmaceuticals Limited. Terizidone - summary of product characteristics [Internet]. 2018 [cited 2019 Jul 7]. Available from: https:\/\/extranet.who.int\/prequal\/sites\/default\/files\/TB303part4v1.pdf."},{"key":"cit0206","unstructured":"Hospira UK Ltd. Amikacin [Internet]. 2015 [cited 2019 Jul 7]. Available from: https:\/\/www.medicines.org.uk\/emc\/product\/3784\/smpc."},{"key":"cit0207","unstructured":"Wyeth Pharmaceuticals Inc. Trecator [Internet]. 2018. [cited 2019 Jul 1]. Available from: http:\/\/labeling.pfizer.com\/showlabeling.aspx?id=473."},{"key":"cit0208","unstructured":"Micro Labs Ltd. Protionamide [Internet]. 2016 [cited 2019 Jul 7]. Available from: https:\/\/extranet.who.int\/prequal\/sites\/default\/files\/TB239part4v02.pdf"},{"key":"cit0209","unstructured":"Otsuka Novel Products GmbH. Deltyba [Internet]. 2019 [cited 2019 Jul 7]. Available from: https:\/\/www.medicines.org.uk\/emc\/product\/5413\/smpc"},{"key":"cit0210","unstructured":"Lucane Pharma. Granupas [Internet]. [cited 2019 Jul 7]. Available from: http:\/\/ec.europa.eu\/health\/documents\/community-register\/2018\/20181218143055\/anx_143055_en.pdf"},{"key":"cit0211","unstructured":"Merck Sharp & Dohme Limited. Primaxin [Internet]. 2018 [cited 2019 Jul 7]. Available from: https:\/\/www.medicines.org.uk\/emc\/product\/1515\/smpc."},{"key":"cit0212","unstructured":"Pfizer Limited. Meronem [Internet]. 2019 [cited 2019 Jul 7]. Available from: https:\/\/www.medicines.org.uk\/emc\/product\/6731\/smpc."},{"key":"cit0213","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1093\/cid\/cis410","volume":"55","author":"Mayer KH","year":"2012","journal-title":"Clin Infect Dis"},{"key":"cit0214","unstructured":"World Health Organization. Latent TB infection: updated and consolidated guidelines for programmatic management. 2018. [cited 2019 Nov 25]. Available from: https:\/\/www.who.int\/tb\/publications\/2018\/latent-tuberculosis-infection\/en\/."},{"key":"cit0215","volume-title":"Conf. Retrovir. Opportunistic Infect","author":"Gupta A","year":"2018"},{"key":"cit0216","volume-title":"Conf. Retrovir. Opportunistic Infect","author":"Salazar-Austin N","year":"2019"},{"key":"cit0217","unstructured":"WHO Organization. Statement on DTG [Internet]. 2018. [cited 2019 May 30]. Available from: https:\/\/www.who.int\/hiv\/WHO_q-and-a-DTG-21may2018.pdf?ua=1"},{"key":"cit0218","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1056\/NEJMc1807653","volume":"379","author":"Zash R","year":"2018","journal-title":"N Engl J Med"},{"key":"cit0219","volume-title":"Conf. Retrovir. Opportunistic Infect; March 4\u20137; Seattle","author":"Hare CB","year":"2019"},{"key":"cit0220","doi-asserted-by":"crossref","first-page":"125","DOI":"10.5588\/ijtld.17.0486","volume":"22","author":"Swindells S","year":"2018","journal-title":"Int J Tuberc Lung Dis"},{"key":"cit0221","unstructured":"Nicole C, Ammerman EN. Long-acting injectables for TB prevention in people living with HIV: prospects and challenges. 2019."}],"container-title":["Expert Opinion on Drug Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/14740338.2020.1694901","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,22]],"date-time":"2021-04-22T13:48:23Z","timestamp":1619099303000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/14740338.2020.1694901"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,6]]},"references-count":221,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1,2]]}},"alternative-id":["10.1080\/14740338.2020.1694901"],"URL":"https:\/\/doi.org\/10.1080\/14740338.2020.1694901","relation":{},"ISSN":["1474-0338","1744-764X"],"issn-type":[{"value":"1474-0338","type":"print"},{"value":"1744-764X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12,6]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ieds20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ieds20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2019-07-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-11-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-12-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}