{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T23:37:07Z","timestamp":1783035427081,"version":"3.54.6"},"reference-count":102,"publisher":"Informa UK Limited","issue":"6","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Opinion on Drug Safety"],"published-print":{"date-parts":[[2022,6,3]]},"DOI":"10.1080\/14740338.2022.2071867","type":"journal-article","created":{"date-parts":[[2022,5,3]],"date-time":"2022-05-03T08:40:29Z","timestamp":1651567229000},"page":"813-831","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":18,"title":["A review of potential neuropathological changes associated with ketamine"],"prefix":"10.1080","volume":"21","author":[{"given":"Danica","family":"Nogo","sequence":"first","affiliation":[{"name":"Mood Disorders Psychopharmacology Unit, University Health Network, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hana","family":"Nazal","sequence":"additional","affiliation":[{"name":"Mood Disorders Psychopharmacology Unit, University Health Network, Ontario, Canada"},{"name":"McMaster University, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuetong","family":"Song","sequence":"additional","affiliation":[{"name":"Mood Disorders Psychopharmacology Unit, University Health Network, Ontario, Canada"},{"name":"University of Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kayla M.","family":"Teopiz","sequence":"additional","affiliation":[{"name":"Mood Disorders Psychopharmacology Unit, University Health Network, Ontario, Canada"},{"name":"University of Toronto, Ontario, Canada"},{"name":"Brain and Cognition Discovery Foundation, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger","family":"Ho","sequence":"additional","affiliation":[{"name":"Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore"},{"name":"Institute for Health Innovation and Technology (Ihealthtech), National University of Singapore, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger S.","family":"McIntyre","sequence":"additional","affiliation":[{"name":"Mood Disorders Psychopharmacology Unit, University Health Network, Ontario, Canada"},{"name":"University of Toronto, Ontario, Canada"},{"name":"Brain and Cognition Discovery Foundation, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leanna M.W.","family":"Lui","sequence":"additional","affiliation":[{"name":"Mood Disorders Psychopharmacology Unit, University Health Network, Ontario, Canada"},{"name":"University of Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua D.","family":"Rosenblat","sequence":"additional","affiliation":[{"name":"Mood Disorders Psychopharmacology Unit, University Health Network, Ontario, Canada"},{"name":"University of Toronto, Ontario, Canada"},{"name":"Brain and Cognition Discovery Foundation, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2022,5,8]]},"reference":[{"key":"cit0001","doi-asserted-by":"publisher","DOI":"10.1186\/1741-7015-9-90"},{"key":"cit0002","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpr.2007.02.005"},{"key":"cit0003","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1997.01830230015002"},{"key":"cit0004","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-publhealth-031912-114409"},{"key":"cit0005","doi-asserted-by":"publisher","DOI":"10.2147\/PPA.S29716"},{"key":"cit0006","doi-asserted-by":"publisher","DOI":"10.1186\/s12888-019-2222-4"},{"key":"cit0007","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2013.10.043"},{"key":"cit0008","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3223(99)00230-9"},{"key":"cit0009","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2020.06.050"},{"key":"cit0010","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2020.07.083"},{"key":"cit0011","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2015.07.037"},{"key":"cit0012","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-3057(01)00693-1"},{"key":"cit0013","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.63.8.856"},{"key":"cit0014","doi-asserted-by":"publisher","DOI":"10.1002\/da.22063"},{"key":"cit0015","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2016.00047"},{"key":"cit0016","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2021.113993"},{"key":"cit0017","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2020.11.020"},{"key":"cit0018","doi-asserted-by":"publisher","DOI":"10.1126\/science.2403696"},{"key":"cit0019","doi-asserted-by":"publisher","DOI":"10.1097\/00001756-199310000-00004"},{"key":"cit0020","doi-asserted-by":"publisher","DOI":"10.1006\/exnr.1993.1153"},{"key":"cit0021","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(95)00842-E"},{"key":"cit0022","doi-asserted-by":"publisher","DOI":"10.1038\/nm0498-460"},{"key":"cit0023","doi-asserted-by":"publisher","DOI":"10.1006\/nbdi.1998.0206"},{"key":"cit0024","doi-asserted-by":"publisher","DOI":"10.3389\/fncir.2018.00037"},{"key":"cit0025","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/7.6.476"},{"key":"cit0026","doi-asserted-by":"publisher","DOI":"10.1038\/srep16778"},{"key":"cit0027","doi-asserted-by":"publisher","DOI":"10.1126\/science.1148045"},{"key":"cit0028","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-007-0708-0"},{"key":"cit0029","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4457-08.2008"},{"key":"cit0030","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbn070"},{"key":"cit0031","doi-asserted-by":"publisher","DOI":"10.1172\/JCI130808"},{"issue":"4","key":"cit0032","first-page":"354","volume":"20","author":"Donegan JJ","year":"2017","journal-title":"Int J Neuropsychopharmacol"},{"key":"cit0033","doi-asserted-by":"publisher","DOI":"10.1172\/JCI130808"},{"key":"cit0034","doi-asserted-by":"publisher","DOI":"10.1021\/bi001290z"},{"issue":"17","key":"cit0035","first-page":"1590","volume":"8","author":"Jin HY","year":"2013","journal-title":"Neural Regen Res"},{"key":"cit0036","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2019.00287"},{"key":"cit0037","doi-asserted-by":"publisher","DOI":"10.1096\/fj.201902135R"},{"key":"cit0038","doi-asserted-by":"publisher","DOI":"10.1126\/science.1835799"},{"key":"cit0039","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2020.00927"},{"key":"cit0040","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/618127"},{"key":"cit0041","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5849(99)00152-5"},{"key":"cit0042","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/89.5.739"},{"key":"cit0043","doi-asserted-by":"publisher","DOI":"10.31887\/DCNS.2000.2.3\/jnewcomer"},{"key":"cit0044","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.00108s3383"},{"key":"cit0045","doi-asserted-by":"publisher","DOI":"10.1177\/0192623310397557"},{"key":"cit0046","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awt162"},{"key":"cit0047","doi-asserted-by":"publisher","DOI":"10.1016\/S0079-6123(05)50015-3"},{"key":"cit0048","doi-asserted-by":"publisher","DOI":"10.1126\/science.2660263"},{"key":"cit0049","doi-asserted-by":"publisher","DOI":"10.1038\/s41398-018-0321-5"},{"key":"cit0050","doi-asserted-by":"publisher","DOI":"10.1038\/tp.2015.136"},{"key":"cit0051","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-014-8798-2"},{"key":"cit0052","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2018.09.031"},{"key":"cit0053","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00079.2008"},{"key":"cit0054","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhu293"},{"key":"cit0055","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2004.03.039"},{"key":"cit0056","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2016.01.023"},{"key":"cit0057","doi-asserted-by":"publisher","DOI":"10.1038\/s41380-020-0740-6"},{"key":"cit0058","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2017.03.010"},{"key":"cit0059","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2019.00372"},{"key":"cit0060","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2013.06.040"},{"key":"cit0061","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2013.02.011"},{"key":"cit0062","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxlet.2019.08.023"},{"key":"cit0063","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxlet.2010.01.008"},{"key":"cit0064","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2013.02.008"},{"key":"cit0065","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0187198"},{"key":"cit0066","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjp.0703479"},{"key":"cit0067","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2004.07.009"},{"key":"cit0068","doi-asserted-by":"publisher","DOI":"10.1213\/00000539-200102000-00016"},{"key":"cit0069","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-8993(01)03338-8"},{"key":"cit0070","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbb.2018.07.003"},{"key":"cit0071","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijdevneu.2009.06.010"},{"key":"cit0072","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbb.2006.05.010"},{"key":"cit0073","doi-asserted-by":"publisher","DOI":"10.3389\/fnana.2013.00023"},{"key":"cit0074","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.5419-08.2009"},{"key":"cit0075","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2004.03.006"},{"key":"cit0076","doi-asserted-by":"publisher","DOI":"10.1177\/1759091420925356"},{"key":"cit0077","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2012.02.046"},{"key":"cit0078","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2005.07.007"},{"key":"cit0079","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-2010-1221"},{"key":"cit0080","first-page":"23","volume-title":"Handbook of clinical neurology","volume":"166","author":"Rolls ET","year":"2019"},{"key":"cit0081","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-444-64196-0.00005-4"},{"key":"cit0082","doi-asserted-by":"publisher","DOI":"10.1007\/s10571-004-6918-7"},{"key":"cit0083","doi-asserted-by":"publisher","DOI":"10.1016\/0165-0270(89)90150-7"},{"key":"cit0084","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0773.1995.tb01041.x"},{"key":"cit0085","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.20705"},{"key":"cit0086","doi-asserted-by":"publisher","DOI":"10.4103\/1673-5374.121696"},{"key":"cit0087","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2020.01784"},{"key":"cit0088","first-page":"268","author":"M\u00fcller VI","year":"2013","journal-title":"Front Hum Neurosci"},{"key":"cit0089","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2012.00323"},{"key":"cit0090","doi-asserted-by":"publisher","DOI":"10.4306\/pi.2017.14.4.441"},{"key":"cit0091","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2007.05.033"},{"key":"cit0092","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2013.10.044"},{"key":"cit0093","doi-asserted-by":"publisher","DOI":"10.1016\/j.nlm.2014.05.003"},{"key":"cit0094","doi-asserted-by":"publisher","DOI":"10.1006\/nimg.1999.0489"},{"key":"cit0095","first-page":"119","volume-title":"Handbook of clinical Neurology","volume":"151","author":"Dieterich M","year":"2018"},{"key":"cit0096","doi-asserted-by":"publisher","DOI":"10.1556\/2060.106.2019.10"},{"key":"cit0097","doi-asserted-by":"publisher","DOI":"10.1053\/j.sult.2010.03.006"},{"key":"cit0098","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.31640"},{"key":"cit0099","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2511080924"},{"key":"cit0100","doi-asserted-by":"publisher","DOI":"10.1177\/1533317507308779"},{"key":"cit0101","doi-asserted-by":"publisher","DOI":"10.1177\/0192623320960705"},{"key":"cit0102","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2016.06.027"}],"container-title":["Expert Opinion on Drug Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/14740338.2022.2071867","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,25]],"date-time":"2022-08-25T12:57:31Z","timestamp":1661432251000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/14740338.2022.2071867"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5,8]]},"references-count":102,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022,6,3]]}},"alternative-id":["10.1080\/14740338.2022.2071867"],"URL":"https:\/\/doi.org\/10.1080\/14740338.2022.2071867","relation":{},"ISSN":["1474-0338","1744-764X"],"issn-type":[{"value":"1474-0338","type":"print"},{"value":"1744-764X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,5,8]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ieds20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ieds20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2021-11-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-26","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-05-08","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}