{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T21:32:01Z","timestamp":1775079121394,"version":"3.50.1"},"reference-count":92,"publisher":"Informa UK Limited","issue":"9","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Opinion on Drug Safety"],"published-print":{"date-parts":[[2022,9,2]]},"DOI":"10.1080\/14740338.2022.2130892","type":"journal-article","created":{"date-parts":[[2022,9,30]],"date-time":"2022-09-30T16:00:46Z","timestamp":1664553646000},"page":"1143-1160","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":2,"title":["An update on the safety of ixazomib for the treatment of multiple myeloma"],"prefix":"10.1080","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1663-0325","authenticated-orcid":false,"given":"Utkarsh","family":"Goel","sequence":"first","affiliation":[{"name":"Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5392-9284","authenticated-orcid":false,"given":"Shaji","family":"Kumar","sequence":"additional","affiliation":[{"name":"Division of Hematology, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2022,10,5]]},"reference":[{"key":"cit0001","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2013.313"},{"key":"cit0002","unstructured":"FDA. KYPROLIS\u00ae (carfilzomib) for injection, for intravenous use 2012 [cited 2022 July\/20]. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2019\/202714s025lbl.pdf"},{"key":"cit0003","unstructured":"FDA. NINLARO\u00ae (ixazomib) capsules, for oral use 2015 [cited 2022 July\/20]. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2015\/208462lbl.pdf"},{"key":"cit0004","unstructured":"FDA. DARZALEX (daratumumab) injection, for intravenous use 2015 [cited 2022 July\/20]. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2016\/761036s004lbl.pdf"},{"key":"cit0005","unstructured":"FDA. EMPLICITI (elotuzumab) for injection, for intravenous use 2015 [cited 2022 July\/20]. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2015\/761035s000lbl.pdf"},{"key":"cit0006","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.25791"},{"issue":"5","key":"cit0007","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1038\/s41408-020-0311-8","volume":"10","author":"Durie BGM","year":"2020","journal-title":"Blood Cancer J"},{"key":"cit0008","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(21)00466-6"},{"key":"cit0009","unstructured":"FDA. SARCLISA\u00ae (isatuximab-irfc) injection, for intravenous use 2020 [cited 2022 July\/20]. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2021\/761113s003lbl.pdf"},{"key":"cit0010","unstructured":"FDA. XPOVIO\u00ae (selinexor) tablets, for oral use 2019 [cited 2022 July 20]. Available from: hhttps:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2020\/212306s005lbl.pdf"},{"key":"cit0011","unstructured":"FDA. BLENREP (belantamab mafodotin-blmf) for injection, for intravenous use 2020 [cited 2022 July\/20]. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2020\/761158s000lbl.pdf"},{"key":"cit0012","unstructured":"FDA. ABECMA\u00ae(idecabtagene vicleucel), suspension for intravenous infusion 2021 [cited 2022 July\/20]. Available from: https:\/\/www.fda.gov\/media\/147055\/download"},{"key":"cit0013","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2020.7561"},{"key":"cit0014","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.14213"},{"key":"cit0015","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-11-0433"},{"issue":"7","key":"cit0016","first-page":"3071","volume":"61","author":"Hideshima T","year":"2001","journal-title":"Cancer Res"},{"key":"cit0017","doi-asserted-by":"publisher","DOI":"10.1038\/nrm3270"},{"key":"cit0018","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.8-6-508"},{"key":"cit0019","unstructured":"Agency EM. Velcade: EPAR - Product Information. 2021."},{"key":"cit0020","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2002.01.133"},{"issue":"8","key":"cit0021","first-page":"2505","author":"Aghajanian C","year":"2002","journal-title":"Clin Cancer Res"},{"key":"cit0022","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa030288"},{"key":"cit0023","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-11-395749"},{"key":"cit0024","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)31594-X"},{"key":"cit0025","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2012-05-425934"},{"key":"cit0026","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1411321"},{"key":"cit0027","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(15)00464-7"},{"key":"cit0028","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(17)30578-8"},{"key":"cit0029","doi-asserted-by":"publisher","DOI":"10.1053\/j.seminoncol.2016.10.008"},{"key":"cit0030","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(20)30452-6"},{"key":"cit0031","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-07-517276"},{"key":"cit0032","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-016-0548-5"},{"key":"cit0033","doi-asserted-by":"publisher","DOI":"10.1136\/esmoopen-2019-000570"},{"key":"cit0034","doi-asserted-by":"publisher","DOI":"10.2217\/fon.11.42"},{"key":"cit0035","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-09-2766"},{"key":"cit0036","doi-asserted-by":"publisher","DOI":"10.1007\/s10637-015-0230-x"},{"key":"cit0037","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-13-1657"},{"key":"cit0038","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-01-548941"},{"key":"cit0039","doi-asserted-by":"publisher","DOI":"10.1007\/s40262-017-0526-4"},{"key":"cit0040","doi-asserted-by":"publisher","DOI":"10.1002\/jcph.719"},{"key":"cit0041","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1516282"},{"key":"cit0042","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.14125"},{"key":"cit0043","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.12991"},{"key":"cit0044","doi-asserted-by":"publisher","DOI":"10.1007\/s00280-018-3671-z"},{"key":"cit0045","doi-asserted-by":"publisher","DOI":"10.1002\/jcph.988"},{"key":"cit0046","doi-asserted-by":"publisher","DOI":"10.1007\/s40262-018-0702-1"},{"key":"cit0047","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2017.185991"},{"key":"cit0048","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.15679"},{"key":"cit0049","doi-asserted-by":"publisher","DOI":"10.1007\/s10637-017-0509-1"},{"key":"cit0050","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2014-01-548826"},{"key":"cit0051","doi-asserted-by":"publisher","DOI":"10.1038\/bcj.2015.60"},{"key":"cit0052","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-05-717769"},{"key":"cit0053","doi-asserted-by":"publisher","DOI":"10.1038\/s41408-021-00593-2"},{"key":"cit0054","doi-asserted-by":"publisher","DOI":"10.1038\/s41375-019-0384-1"},{"key":"cit0055","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-11-0476"},{"key":"cit0056","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.21.00972"},{"key":"cit0057","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-017-0501-4"},{"key":"cit0058","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.13653"},{"issue":"1","key":"cit0059","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1186\/s13063-020-04739-8","volume":"21","author":"Hinsley S","year":"2020","journal-title":"Trials"},{"key":"cit0060","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.17504"},{"key":"cit0061","doi-asserted-by":"publisher","DOI":"10.1038\/s41416-019-0581-8"},{"key":"cit0062","doi-asserted-by":"publisher","DOI":"10.1038\/s41375-018-0038-8"},{"key":"cit0063","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.26361"},{"key":"cit0064","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(14)71125-8"},{"key":"cit0065","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2020008787"},{"key":"cit0066","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2021.280394"},{"key":"cit0067","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1611750"},{"key":"cit0068","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(21)00535-0"},{"key":"cit0069","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2018.09.011"},{"issue":"12","key":"cit0070","doi-asserted-by":"crossref","first-page":"2879","DOI":"10.3324\/haematol.2019.240374","volume":"105","author":"Sonja Z","year":"2020","journal-title":"Haematologica"},{"key":"cit0071","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2020-139372"},{"issue":"1","key":"cit0072","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1182\/blood-2021-146040","volume":"138","author":"Perrot A","year":"2021","journal-title":"Blood"},{"key":"cit0073","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2021.0611"},{"key":"cit0074","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.21.01935"},{"key":"cit0075","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.20.03143"},{"key":"cit0076","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)33003-4"},{"key":"cit0077","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2021-150476"},{"key":"cit0078","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.20.02060"},{"key":"cit0079","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.14733"},{"key":"cit0080","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.29.8216"},{"key":"cit0081","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(11)70081-X"},{"key":"cit0082","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(10)70068-1"},{"key":"cit0083","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.7768-21"},{"key":"cit0084","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-020-04234-9"},{"key":"cit0085","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-021-04663-0"},{"key":"cit0086","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.30.8791"},{"key":"cit0087","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-015-0198-1"},{"key":"cit0088","doi-asserted-by":"publisher","DOI":"10.1016\/j.clml.2017.02.024"},{"key":"cit0089","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(20)30756-7"},{"key":"cit0090","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2016.71.1663"},{"key":"cit0091","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1114083"},{"key":"cit0092","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2014.60.2466"}],"container-title":["Expert Opinion on Drug Safety"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/14740338.2022.2130892","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,15]],"date-time":"2022-10-15T06:34:26Z","timestamp":1665815666000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/14740338.2022.2130892"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,2]]},"references-count":92,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2022,9,2]]}},"alternative-id":["10.1080\/14740338.2022.2130892"],"URL":"https:\/\/doi.org\/10.1080\/14740338.2022.2130892","relation":{},"ISSN":["1474-0338","1744-764X"],"issn-type":[{"value":"1474-0338","type":"print"},{"value":"1744-764X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,2]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ieds20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ieds20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2022-04-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-09-27","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-10-05","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}