{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T22:33:43Z","timestamp":1777674823271,"version":"3.51.4"},"reference-count":57,"publisher":"Informa UK Limited","issue":"1","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"FAR funds"},{"name":"Italian Ministry for Instruction, University and Research"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Journal of Enzyme Inhibition and Medicinal Chemistry"],"published-print":{"date-parts":[[2019,1,1]]},"DOI":"10.1080\/14756366.2019.1611801","type":"journal-article","created":{"date-parts":[[2019,5,10]],"date-time":"2019-05-10T06:07:49Z","timestamp":1557468469000},"page":"1051-1061","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":15,"title":["Fibrate-based\n                    <i>N<\/i>\n                    -acylsulphonamides targeting carbonic anhydrases: synthesis, biochemical evaluation, and docking studies"],"prefix":"10.1080","volume":"34","author":[{"given":"Alessandra","family":"Ammazzalorso","sequence":"first","affiliation":[{"name":"Department of Pharmacy, \u201cG. d\u2019Annunzio\u201d University of Chieti-Pescara","place":["Chieti, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8698-9440","authenticated-orcid":false,"given":"Simone","family":"Carradori","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, \u201cG. d\u2019Annunzio\u201d University of Chieti-Pescara","place":["Chieti, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1470-7192","authenticated-orcid":false,"given":"Andrea","family":"Angeli","sequence":"additional","affiliation":[{"name":"Laboratorio di Chimica Bioinorganica, Universit\u00e0 degli Studi di Firenze","place":["Florence, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atilla","family":"Akdemir","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Faculty of Pharmacy, Computer-Aided Drug Discovery Laboratory, Bezmialem Vakif University","place":["Istanbul, Turkey"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"De Filippis","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, \u201cG. d\u2019Annunzio\u201d University of Chieti-Pescara","place":["Chieti, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marialuigia","family":"Fantacuzzi","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, \u201cG. d\u2019Annunzio\u201d University of Chieti-Pescara","place":["Chieti, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Letizia","family":"Giampietro","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, \u201cG. d\u2019Annunzio\u201d University of Chieti-Pescara","place":["Chieti, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Maccallini","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, \u201cG. d\u2019Annunzio\u201d University of Chieti-Pescara","place":["Chieti, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosa","family":"Amoroso","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, \u201cG. d\u2019Annunzio\u201d University of Chieti-Pescara","place":["Chieti, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4262-0323","authenticated-orcid":false,"given":"Claudiu T.","family":"Supuran","sequence":"additional","affiliation":[{"name":"Laboratorio di Chimica Bioinorganica, Universit\u00e0 degli Studi di Firenze","place":["Florence, Italy"]},{"name":"Neurofarba Department, Section of Pharmaceutical and Nutriceutical Sciences, Universit\u00e0 degli Studi di Firenze","place":["Florence, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2019,5,10]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrd2467"},{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.4155\/fmc.14.68"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.2174\/1385272822666180122153839"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/cbdd.13043"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm1013693"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.04227-14"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3048"},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.5b00698"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsinfecdis.6b00021"},{"key":"e_1_3_2_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2014.02.054"},{"key":"e_1_3_2_11_1","doi-asserted-by":"publisher","DOI":"10.1021\/ol034212n"},{"key":"e_1_3_2_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2015.04.076"},{"key":"e_1_3_2_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/cbdd.13026"},{"key":"e_1_3_2_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2017.11.014"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.3109\/14756366.2012.672983"},{"key":"e_1_3_2_14_3","doi-asserted-by":"publisher","DOI":"10.1080\/14756366.2016.1235042"},{"key":"e_1_3_2_15_1","doi-asserted-by":"publisher","DOI":"10.3109\/14756366.2015.1128427"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1080\/14756366.2016.1244533"},{"key":"e_1_3_2_16_1","doi-asserted-by":"publisher","DOI":"10.1080\/14756366.2016.1235040"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1080\/14756366.2017.1316720"},{"key":"e_1_3_2_17_1","doi-asserted-by":"publisher","DOI":"10.3109\/14756366.2012.658788"},{"key":"e_1_3_2_18_1","doi-asserted-by":"publisher","DOI":"10.1021\/cr200176r"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1080\/13543776.2018.1523897"},{"key":"e_1_3_2_18_3","doi-asserted-by":"publisher","DOI":"10.1080\/14756366.2017.1344236"},{"key":"e_1_3_2_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2014.12.054"},{"key":"e_1_3_2_20_1","doi-asserted-by":"publisher","DOI":"10.1080\/14756366.2018.1446432"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1080\/14756366.2017.1354857"},{"key":"e_1_3_2_21_1","doi-asserted-by":"publisher","DOI":"10.1039\/c1cc14575d"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0223-5234(97)86179-X"},{"key":"e_1_3_2_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2011.06.028"},{"key":"e_1_3_2_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2012.10.019"},{"key":"e_1_3_2_24_1","doi-asserted-by":"publisher","DOI":"10.2174\/157340641001131226123613"},{"key":"e_1_3_2_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2014.06.003"},{"key":"e_1_3_2_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2014.07.014"},{"key":"e_1_3_2_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/prot.22234"},{"key":"e_1_3_2_28_1","doi-asserted-by":"publisher","DOI":"10.3109\/14756366.2014.892936"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1080\/14756366.2018.1499628"},{"key":"e_1_3_2_28_3","doi-asserted-by":"publisher","DOI":"10.1080\/14756366.2017.1380638"},{"key":"e_1_3_2_29_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0178995"},{"key":"e_1_3_2_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.25648"},{"key":"e_1_3_2_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2016.02.064"},{"key":"e_1_3_2_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)62326-9"},{"key":"e_1_3_2_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2017.08.009"},{"key":"e_1_3_2_34_1","doi-asserted-by":"publisher","DOI":"10.1080\/17460441.2017.1253677"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1042\/BCJ20160115"},{"key":"e_1_3_2_34_3","doi-asserted-by":"publisher","DOI":"10.1038\/nrd3554"},{"key":"e_1_3_2_34_4","doi-asserted-by":"publisher","DOI":"10.2174\/1568016043477305"},{"key":"e_1_3_2_34_5","doi-asserted-by":"publisher","DOI":"10.1080\/14756366.2018.1515933"},{"key":"e_1_3_2_35_1","doi-asserted-by":"publisher","DOI":"10.3109\/14756366.2015.1122001"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1080\/14756360500141911"},{"key":"e_1_3_2_35_3","doi-asserted-by":"publisher","DOI":"10.1002\/jps.2600830603"},{"key":"e_1_3_2_35_4","doi-asserted-by":"publisher","DOI":"10.3109\/14756366.2015.1059333"},{"key":"e_1_3_2_35_5","doi-asserted-by":"publisher","DOI":"10.1080\/14756366.2017.1349764"},{"key":"e_1_3_2_36_1","doi-asserted-by":"publisher","DOI":"10.1517\/13543776.13.10.1545"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1021\/jm060807n"},{"key":"e_1_3_2_36_3","doi-asserted-by":"publisher","DOI":"10.1080\/14756366.2016.1243536"},{"key":"e_1_3_2_36_4","doi-asserted-by":"publisher","DOI":"10.1080\/14756366.2016.1235043"}],"container-title":["Journal of Enzyme Inhibition and Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/tandfonline.com\/doi\/pdf\/10.1080\/14756366.2019.1611801","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/14756366.2019.1611801","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T08:13:43Z","timestamp":1777450423000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/14756366.2019.1611801"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,1]]},"references-count":57,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1,1]]}},"alternative-id":["10.1080\/14756366.2019.1611801"],"URL":"https:\/\/doi.org\/10.1080\/14756366.2019.1611801","relation":{},"ISSN":["1475-6366","1475-6374"],"issn-type":[{"value":"1475-6366","type":"print"},{"value":"1475-6374","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1,1]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ienz20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ienz20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2019-03-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-04-17","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-04-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-05-10","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}