{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T16:23:17Z","timestamp":1778689397517,"version":"3.51.4"},"reference-count":40,"publisher":"Informa UK Limited","issue":"1","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Journal of Enzyme Inhibition and Medicinal Chemistry"],"published-print":{"date-parts":[[2019,1,1]]},"DOI":"10.1080\/14756366.2019.1666836","type":"journal-article","created":{"date-parts":[[2019,9,20]],"date-time":"2019-09-20T03:27:46Z","timestamp":1568950066000},"page":"1697-1710","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":31,"title":["Novel 2-substituted-benzimidazole-6-sulfonamides as carbonic anhydrase inhibitors: synthesis, biological evaluation against isoforms I, II, IX and XII and molecular docking studies"],"prefix":"10.1080","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1000-1376","authenticated-orcid":false,"given":"Ciro","family":"Milite","sequence":"first","affiliation":[{"name":"Department of Pharmacy, Epigenetic Med Chem Lab, University of Salerno","place":["Fisciano (SA), Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4271-5031","authenticated-orcid":false,"given":"Giorgio","family":"Amendola","sequence":"additional","affiliation":[{"name":"DiSTABiF, Universit\u00e0 della Campania Luigi Vanvitelli","place":["Caserta, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3342-702X","authenticated-orcid":false,"given":"Alessio","family":"Nocentini","sequence":"additional","affiliation":[{"name":"NEUROFARBA Department, Sezione di Scienze Farmaceutiche e Nutraceutiche, Universit\u00e0 degli Studi di Firenze","place":["Sesto Fiorentino (Florence), Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0107-2682","authenticated-orcid":false,"given":"Silvia","family":"Bua","sequence":"additional","affiliation":[{"name":"NEUROFARBA Department, Sezione di Scienze Farmaceutiche e Nutraceutiche, Universit\u00e0 degli Studi di Firenze","place":["Sesto Fiorentino (Florence), Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9062-5914","authenticated-orcid":false,"given":"Alessandra","family":"Cipriano","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Epigenetic Med Chem Lab, University of Salerno","place":["Fisciano (SA), Italy"]},{"name":"PhD Program in Drug Discovery and Development, University of Salerno","place":["Fisciano (SA), Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9814-7195","authenticated-orcid":false,"given":"Elisabetta","family":"Barresi","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Universy of Pisa","place":["Pisa, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8960-7858","authenticated-orcid":false,"given":"Alessandra","family":"Feoli","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Epigenetic Med Chem Lab, University of Salerno","place":["Fisciano (SA), Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2181-2142","authenticated-orcid":false,"given":"Ettore","family":"Novellino","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, University Federico II of Naples","place":["Naples, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7897-7917","authenticated-orcid":false,"given":"Federico","family":"Da Settimo","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Universy of Pisa","place":["Pisa, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4262-0323","authenticated-orcid":false,"given":"Claudiu T.","family":"Supuran","sequence":"additional","affiliation":[{"name":"NEUROFARBA Department, Sezione di Scienze Farmaceutiche e Nutraceutiche, Universit\u00e0 degli Studi di Firenze","place":["Sesto Fiorentino (Florence), Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7449-3704","authenticated-orcid":false,"given":"Sabrina","family":"Castellano","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Epigenetic Med Chem Lab, University of Salerno","place":["Fisciano (SA), Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8900-0968","authenticated-orcid":false,"given":"Sandro","family":"Cosconati","sequence":"additional","affiliation":[{"name":"DiSTABiF, Universit\u00e0 della Campania Luigi Vanvitelli","place":["Caserta, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8675-939X","authenticated-orcid":false,"given":"Sabrina","family":"Taliani","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Universy of Pisa","place":["Pisa, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2019,9,20]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"publisher","DOI":"10.1042\/BCJ20160115"},{"key":"e_1_3_3_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrd2467"},{"key":"e_1_3_3_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2007.04.020"},{"key":"e_1_3_3_5_1","doi-asserted-by":"publisher","DOI":"10.2174\/156802607780636690"},{"key":"e_1_3_3_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/13543784.2018.1548608"},{"key":"e_1_3_3_7_1","doi-asserted-by":"publisher","DOI":"10.4155\/fmc.14.68"},{"key":"e_1_3_3_8_1","doi-asserted-by":"publisher","DOI":"10.3109\/14756366.2015.1122001"},{"key":"e_1_3_3_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2016.01.020"},{"key":"e_1_3_3_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2015.06.050"},{"key":"e_1_3_3_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2014.03.041"},{"key":"e_1_3_3_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0223-5234(98)80049-4"},{"key":"e_1_3_3_13_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm2010404"},{"key":"e_1_3_3_14_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm7015705"},{"key":"e_1_3_3_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2009.01.038"},{"key":"e_1_3_3_16_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules21121649"},{"key":"e_1_3_3_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2011.01.016"},{"key":"e_1_3_3_18_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm1013242"},{"key":"e_1_3_3_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)62326-9"},{"key":"e_1_3_3_20_1","doi-asserted-by":"publisher","DOI":"10.1080\/14756366.2018.1428572"},{"key":"e_1_3_3_21_1","doi-asserted-by":"publisher","DOI":"10.1080\/14756366.2017.1405263"},{"key":"e_1_3_3_22_1","doi-asserted-by":"publisher","DOI":"10.1080\/14756366.2017.1356295"},{"key":"e_1_3_3_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200701189"},{"key":"e_1_3_3_24_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm060807n"},{"key":"e_1_3_3_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2003.12.029"},{"key":"e_1_3_3_26_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm9900523"},{"key":"e_1_3_3_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0968-0896(99)00190-X"},{"key":"e_1_3_3_28_1","doi-asserted-by":"publisher","DOI":"10.1080\/14756366.2017.1316720"},{"key":"e_1_3_3_29_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm301625s"},{"key":"e_1_3_3_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0223-5234(97)86179-X"},{"key":"e_1_3_3_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.21256"},{"key":"e_1_3_3_32_1","doi-asserted-by":"publisher","DOI":"10.1021\/ci500209e"},{"key":"e_1_3_3_33_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.5b01343"},{"key":"e_1_3_3_34_1","unstructured":"Schr\u00f6dinger Release 2018-3: Maestro Schr\u00f6dinger (2018)."},{"key":"e_1_3_3_35_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.8b00770"},{"key":"e_1_3_3_36_1","doi-asserted-by":"publisher","DOI":"10.1107\/S0907444910006554"},{"key":"e_1_3_3_37_1","doi-asserted-by":"publisher","DOI":"10.2210\/pdb5MSA\/pdb"},{"key":"e_1_3_3_38_1","doi-asserted-by":"publisher","DOI":"10.1517\/17460441.2010.484460"},{"key":"e_1_3_3_39_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm0495935"},{"key":"e_1_3_3_40_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.8b00670"},{"key":"e_1_3_3_41_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0908301106"}],"container-title":["Journal of Enzyme Inhibition and Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/14756366.2019.1666836","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T08:14:10Z","timestamp":1777450450000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/14756366.2019.1666836"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1,1]]},"references-count":40,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1,1]]}},"alternative-id":["10.1080\/14756366.2019.1666836"],"URL":"https:\/\/doi.org\/10.1080\/14756366.2019.1666836","relation":{},"ISSN":["1475-6366","1475-6374"],"issn-type":[{"value":"1475-6366","type":"print"},{"value":"1475-6374","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1,1]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ienz20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ienz20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2019-07-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-09-05","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-09-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-09-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}